JP2024123220A5 - - Google Patents
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- Publication number
- JP2024123220A5 JP2024123220A5 JP2024102853A JP2024102853A JP2024123220A5 JP 2024123220 A5 JP2024123220 A5 JP 2024123220A5 JP 2024102853 A JP2024102853 A JP 2024102853A JP 2024102853 A JP2024102853 A JP 2024102853A JP 2024123220 A5 JP2024123220 A5 JP 2024123220A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- fak inhibitor
- use according
- fak
- release
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 31
- 229940124783 FAK inhibitor Drugs 0.000 claims 17
- 238000013268 sustained release Methods 0.000 claims 4
- 239000012730 sustained-release form Substances 0.000 claims 4
- 239000000017 hydrogel Substances 0.000 claims 3
- 239000011148 porous material Substances 0.000 claims 3
- 102000016621 Focal Adhesion Protein-Tyrosine Kinases Human genes 0.000 claims 2
- 108010067715 Focal Adhesion Protein-Tyrosine Kinases Proteins 0.000 claims 2
- 230000035876 healing Effects 0.000 claims 2
- SRSXLGNVWSONIS-UHFFFAOYSA-N benzenesulfonic acid Chemical class OS(=O)(=O)C1=CC=CC=C1 SRSXLGNVWSONIS-UHFFFAOYSA-N 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- 230000037390 scarring Effects 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862672513P | 2018-05-16 | 2018-05-16 | |
| US62/672,513 | 2018-05-16 | ||
| US201962848515P | 2019-05-15 | 2019-05-15 | |
| US62/848,515 | 2019-05-15 | ||
| JP2020564323A JP7585045B2 (ja) | 2018-05-16 | 2019-05-16 | 瘢痕形成の減少の為の接着斑キナーゼ阻害剤の制御されたヒドロゲル送達 |
| PCT/US2019/032697 WO2019222520A1 (en) | 2018-05-16 | 2019-05-16 | Controlled hydrogel delivery of focal adhesion kinase inhibitor for decreased scar formation |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020564323A Division JP7585045B2 (ja) | 2018-05-16 | 2019-05-16 | 瘢痕形成の減少の為の接着斑キナーゼ阻害剤の制御されたヒドロゲル送達 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024123220A JP2024123220A (ja) | 2024-09-10 |
| JP2024123220A5 true JP2024123220A5 (https=) | 2024-12-19 |
Family
ID=68540759
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020564323A Active JP7585045B2 (ja) | 2018-05-16 | 2019-05-16 | 瘢痕形成の減少の為の接着斑キナーゼ阻害剤の制御されたヒドロゲル送達 |
| JP2024102853A Pending JP2024123220A (ja) | 2018-05-16 | 2024-06-26 | 瘢痕形成の減少の為の接着斑キナーゼ阻害剤の制御されたヒドロゲル送達 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020564323A Active JP7585045B2 (ja) | 2018-05-16 | 2019-05-16 | 瘢痕形成の減少の為の接着斑キナーゼ阻害剤の制御されたヒドロゲル送達 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US12178940B2 (https=) |
| EP (1) | EP3793589B1 (https=) |
| JP (2) | JP7585045B2 (https=) |
| CN (1) | CN112384238A (https=) |
| AU (2) | AU2019269608B2 (https=) |
| CA (1) | CA3100352A1 (https=) |
| ES (1) | ES2980620T3 (https=) |
| WO (1) | WO2019222520A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019222520A1 (en) * | 2018-05-16 | 2019-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Controlled hydrogel delivery of focal adhesion kinase inhibitor for decreased scar formation |
| CN115335121A (zh) * | 2020-03-26 | 2022-11-11 | 斯坦福大学托管董事会 | 用于组织再生的方法及其试剂盒 |
| WO2022191812A1 (en) * | 2021-03-08 | 2022-09-15 | National Cheng Kung University | Method of facilitating wound-induced hair follicle neogenesis, tissue regeneration and reducing wound stiffness |
| WO2023009439A1 (en) * | 2021-07-30 | 2023-02-02 | The Board Of Trustees Of The Leland Stanford Junior University | Mechanotransduction disruption mediation in skin grafting methods and compositions for use in practicing the same |
| CN120981256A (zh) * | 2023-02-24 | 2025-11-18 | 陶特纳集团研究与发展有限责任公司 | 伤口敷料组件 |
| TW202528357A (zh) * | 2023-12-08 | 2025-07-16 | 美商普瑞諾生物科技公司 | 用於降低瘢痕形成及治療皮膚傷口之方法及組成物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3973420B2 (ja) * | 2001-12-28 | 2007-09-12 | ライフケア技研株式会社 | 創傷被覆材の製造方法 |
| US8062661B2 (en) * | 2003-12-11 | 2011-11-22 | Teikoku Pharma Usa, Inc. | Methods and compositions for treating skin wounds |
| EP2054089B1 (en) | 2006-08-03 | 2018-12-26 | The Board of Trustees of the Leland Stanford Junior University | Devices and bandages for the treatment or prevention of scars and/or keloids and methods and kits therefor |
| US9636362B2 (en) * | 2010-03-04 | 2017-05-02 | The Board Of Trustees Of The Leland Stanford Junior University | Pullulan regenerative matrix |
| CN103313732B (zh) | 2010-11-12 | 2017-07-25 | 日产化学工业株式会社 | 含有脂质肽型胶凝剂和高分子化合物的凝胶片 |
| US9655967B2 (en) * | 2011-12-09 | 2017-05-23 | The Board Of Trustees Of The Leland Stanford Junior University | Inhibition of focal adhesion kinase for control of scar tissue formation |
| US20140072613A1 (en) * | 2012-09-10 | 2014-03-13 | Cynthia Lander | Compositions and Methods for Treating Cutaneous Scarring |
| WO2019222520A1 (en) * | 2018-05-16 | 2019-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Controlled hydrogel delivery of focal adhesion kinase inhibitor for decreased scar formation |
-
2019
- 2019-05-16 WO PCT/US2019/032697 patent/WO2019222520A1/en not_active Ceased
- 2019-05-16 US US17/049,359 patent/US12178940B2/en active Active
- 2019-05-16 JP JP2020564323A patent/JP7585045B2/ja active Active
- 2019-05-16 EP EP19803736.8A patent/EP3793589B1/en active Active
- 2019-05-16 ES ES19803736T patent/ES2980620T3/es active Active
- 2019-05-16 CN CN201980045397.7A patent/CN112384238A/zh active Pending
- 2019-05-16 CA CA3100352A patent/CA3100352A1/en active Pending
- 2019-05-16 AU AU2019269608A patent/AU2019269608B2/en active Active
-
2024
- 2024-06-26 JP JP2024102853A patent/JP2024123220A/ja active Pending
-
2025
- 2025-07-03 AU AU2025205095A patent/AU2025205095A1/en active Pending
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