JP2024105436A5 - - Google Patents
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- JP2024105436A5 JP2024105436A5 JP2024075642A JP2024075642A JP2024105436A5 JP 2024105436 A5 JP2024105436 A5 JP 2024105436A5 JP 2024075642 A JP2024075642 A JP 2024075642A JP 2024075642 A JP2024075642 A JP 2024075642A JP 2024105436 A5 JP2024105436 A5 JP 2024105436A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- patient
- composition according
- affected skin
- trunk
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 16
- 206010047642 Vitiligo Diseases 0.000 claims 5
- 210000003141 lower extremity Anatomy 0.000 claims 4
- 239000002144 L01XE18 - Ruxolitinib Substances 0.000 claims 3
- HFNKQEVNSGCOJV-OAHLLOKOSA-N ruxolitinib Chemical compound C1([C@@H](CC#N)N2N=CC(=C2)C=2C=3C=CNC=3N=CN=2)CCCC1 HFNKQEVNSGCOJV-OAHLLOKOSA-N 0.000 claims 3
- 229960000215 ruxolitinib Drugs 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 230000001815 facial effect Effects 0.000 claims 2
- 239000012458 free base Substances 0.000 claims 2
- 239000006071 cream Substances 0.000 claims 1
- 239000007764 o/w emulsion Substances 0.000 claims 1
- 238000001126 phototherapy Methods 0.000 claims 1
- 229960002539 ruxolitinib phosphate Drugs 0.000 claims 1
- JFMWPOCYMYGEDM-XFULWGLBSA-N ruxolitinib phosphate Chemical compound OP(O)(O)=O.C1([C@@H](CC#N)N2N=CC(=C2)C=2C=3C=CNC=3N=CN=2)CCCC1 JFMWPOCYMYGEDM-XFULWGLBSA-N 0.000 claims 1
Applications Claiming Priority (26)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962859584P | 2019-06-10 | 2019-06-10 | |
| US201962859506P | 2019-06-10 | 2019-06-10 | |
| US201962859601P | 2019-06-10 | 2019-06-10 | |
| US201962859495P | 2019-06-10 | 2019-06-10 | |
| US201962859532P | 2019-06-10 | 2019-06-10 | |
| US62/859,532 | 2019-06-10 | ||
| US62/859,601 | 2019-06-10 | ||
| US62/859,495 | 2019-06-10 | ||
| US62/859,506 | 2019-06-10 | ||
| US62/859,584 | 2019-06-10 | ||
| US201962894564P | 2019-08-30 | 2019-08-30 | |
| US201962894514P | 2019-08-30 | 2019-08-30 | |
| US201962894541P | 2019-08-30 | 2019-08-30 | |
| US201962894581P | 2019-08-30 | 2019-08-30 | |
| US201962894496P | 2019-08-30 | 2019-08-30 | |
| US62/894,581 | 2019-08-30 | ||
| US62/894,514 | 2019-08-30 | ||
| US62/894,496 | 2019-08-30 | ||
| US62/894,564 | 2019-08-30 | ||
| US62/894,541 | 2019-08-30 | ||
| US201962911845P | 2019-10-07 | 2019-10-07 | |
| US62/911,845 | 2019-10-07 | ||
| US202062967879P | 2020-01-30 | 2020-01-30 | |
| US62/967,879 | 2020-01-30 | ||
| JP2022521405A JP7532511B2 (ja) | 2019-06-10 | 2020-06-10 | Ｊａｋ阻害剤による尋常性白斑の局所治療 |
| PCT/US2020/036985 WO2020252012A1 (en) | 2019-06-10 | 2020-06-10 | Topical treatment of vitiligo by a jak inhibitor |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022521405A Division JP7532511B2 (ja) | 2019-06-10 | 2020-06-10 | Ｊａｋ阻害剤による尋常性白斑の局所治療 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024105436A JP2024105436A (ja) | 2024-08-06 |
| JP2024105436A5 true JP2024105436A5 (https=) | 2025-01-20 |
Family
ID=73651112
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022521405A Active JP7532511B2 (ja) | 2019-06-10 | 2020-06-10 | Ｊａｋ阻害剤による尋常性白斑の局所治療 |
| JP2024075642A Pending JP2024105436A (ja) | 2019-06-10 | 2024-05-08 | Ｊａｋ阻害剤による尋常性白斑の局所治療 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022521405A Active JP7532511B2 (ja) | 2019-06-10 | 2020-06-10 | Ｊａｋ阻害剤による尋常性白斑の局所治療 |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US20200405627A1 (https=) |
| EP (1) | EP3982971A4 (https=) |
| JP (2) | JP7532511B2 (https=) |
| AU (2) | AU2020290995B2 (https=) |
| CA (1) | CA3150975A1 (https=) |
| IL (1) | IL290637A (https=) |
| MA (1) | MA56215A (https=) |
| TW (1) | TW202112377A (https=) |
| WO (1) | WO2020252012A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102821964B1 (ko) | 2017-11-03 | 2025-06-19 | 어클라리스 쎄라퓨틱스, 인코포레이티드 | 치환된 피롤로피리미딘 jak 억제제 및 이의 제조 및 사용 방법 |
| CN119080779A (zh) | 2018-08-10 | 2024-12-06 | 阿克拉瑞斯治疗股份有限公司 | 吡咯并嘧啶itk抑制剂 |
| JP7532511B2 (ja) | 2019-06-10 | 2024-08-13 | インサイト・コーポレイション | Ｊａｋ阻害剤による尋常性白斑の局所治療 |
| WO2022061351A1 (en) * | 2020-09-16 | 2022-03-24 | Incyte Corporation | Topical treatment of vitiligo |
| TW202302104A (zh) * | 2021-02-18 | 2023-01-16 | 美商阿克拉里斯醫療股份有限公司 | Jak 1/3抑制劑的局部配方及其用於治療異位性皮膚炎和其他皮膚狀況之用法 |
| CN117279915A (zh) * | 2021-02-18 | 2023-12-22 | 阿克拉瑞斯治疗股份有限公司 | Jak1/3抑制剂的局部制剂及其用于特异性皮炎和其他皮肤病况的治疗的方法 |
| EP4389114A4 (en) * | 2021-08-19 | 2025-09-03 | Zhuhai United Laboratories Co Ltd | LOCAL TOPICAL FORMULATION CONTAINING A JAK INHIBITOR OR A SALT THEREOF OR A CRYSTALLINE FORM THEREOF, PREPARATION METHOD THEREOF AND CORRESPONDING APPLICATION |
| CN115869321A (zh) | 2021-09-28 | 2023-03-31 | 杭州中美华东制药有限公司 | 一种芦可替尼组合物及其制备方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5521184A (en) | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
| PT1107964E (pt) | 1998-08-11 | 2010-06-11 | Novartis Ag | Derivados de isoquinolina com actividade inibidora da angiogénese |
| US6133031A (en) | 1999-08-19 | 2000-10-17 | Isis Pharmaceuticals Inc. | Antisense inhibition of focal adhesion kinase expression |
| GB9905075D0 (en) | 1999-03-06 | 1999-04-28 | Zeneca Ltd | Chemical compounds |
| GB0004890D0 (en) | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
| BR0212760A (pt) | 2001-09-19 | 2004-12-07 | Aventis Pharma Sa | Compostos quìmicos |
| DE60213842T2 (de) | 2001-10-30 | 2007-09-06 | Novartis Ag | Staurosporin-derivate als hemmer der flt3-rezeptor-tyrosinkinase-wirkung |
| PE20040522A1 (es) | 2002-05-29 | 2004-09-28 | Novartis Ag | Derivados de diarilurea dependientes de la cinasa de proteina |
| GB0215676D0 (en) | 2002-07-05 | 2002-08-14 | Novartis Ag | Organic compounds |
| EP1542768A1 (en) | 2002-09-20 | 2005-06-22 | Alcon, Inc. | Use of cytokine synthesis inhibitors for the treatment of dry eye disorders |
| TWI335913B (en) | 2002-11-15 | 2011-01-11 | Vertex Pharma | Diaminotriazoles useful as inhibitors of protein kinases |
| UA80767C2 (en) | 2002-12-20 | 2007-10-25 | Pfizer Prod Inc | Pyrimidine derivatives for the treatment of abnormal cell growth |
| GB0305929D0 (en) | 2003-03-14 | 2003-04-23 | Novartis Ag | Organic compounds |
| AR045944A1 (es) | 2003-09-24 | 2005-11-16 | Novartis Ag | Derivados de isoquinolina 1.4-disustituidas |
| AU2005309019A1 (en) | 2004-11-24 | 2006-06-01 | Novartis Ag | Combinations of JAK inhibitors and at least one of Bcr-Abl, Flt-3, FAK or RAF kinase inhibitors |
| SG10202003901UA (en) | 2005-12-13 | 2020-05-28 | Incyte Holdings Corp | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors |
| KR20150036210A (ko) | 2007-06-13 | 2015-04-07 | 인사이트 코포레이션 | 야누스 키나제 억제제（Ｒ）―３―（４―（７Ｈ―피롤로［２，３－ｄ］피리미딘―4―일）―1Ｈ―피라졸―1―일）―３―사이클로펜틸프로판니트릴의 염 |
| PE20130216A1 (es) | 2010-05-21 | 2013-02-27 | Incyte Corp | Formulacion topica para un inhibidor de jak |
| AU2017358703A1 (en) | 2016-11-10 | 2019-05-09 | Galapagos Nv | Compounds and pharmaceutical compositions thereof for the treatment of inflammatory diseases |
| US11957931B2 (en) | 2017-04-26 | 2024-04-16 | Yale University | Compositions and methods for treating vitiligo |
| US20190060311A1 (en) | 2017-08-24 | 2019-02-28 | Aclaris Therapeutics, Inc. | Compositions and methods for treatment of vitiligo |
| MA52655A (fr) | 2018-03-30 | 2021-02-17 | Incyte Corp | Biomarqueurs pour maladie cutanée inflammatoire |
| CN111374639A (zh) | 2018-12-28 | 2020-07-07 | 陈柏龄 | 败血症的菌种预测系统与方法 |
| US20210030672A1 (en) | 2019-06-10 | 2021-02-04 | Incyte Corporation | Topical treatment of vitiligo by a jak inhibitor |
| JP7532511B2 (ja) * | 2019-06-10 | 2024-08-13 | インサイト・コーポレイション | Ｊａｋ阻害剤による尋常性白斑の局所治療 |
-
2020
- 2020-06-10 JP JP2022521405A patent/JP7532511B2/ja active Active
- 2020-06-10 US US16/897,927 patent/US20200405627A1/en not_active Abandoned
- 2020-06-10 EP EP20823024.3A patent/EP3982971A4/en active Pending
- 2020-06-10 AU AU2020290995A patent/AU2020290995B2/en active Active
- 2020-06-10 CA CA3150975A patent/CA3150975A1/en active Pending
- 2020-06-10 US US16/897,923 patent/US11602536B2/en active Active
- 2020-06-10 MA MA056215A patent/MA56215A/fr unknown
- 2020-06-10 WO PCT/US2020/036985 patent/WO2020252012A1/en not_active Ceased
- 2020-06-10 TW TW109119535A patent/TW202112377A/zh unknown
-
2022
- 2022-02-15 IL IL290637A patent/IL290637A/en unknown
- 2022-07-08 US US17/860,884 patent/US11590138B2/en active Active
- 2022-12-08 US US18/077,315 patent/US12233067B2/en active Active
-
2024
- 2024-05-08 JP JP2024075642A patent/JP2024105436A/ja active Pending
-
2026
- 2026-01-21 AU AU2026200410A patent/AU2026200410A1/en active Pending
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