JP2024044566A - Cleaning composition containing etofenprox - Google Patents

Abstract

[Problem] To provide a cleaning composition. In particular, to provide a cleaning composition suitable for direct application to animals, application in foam form, and use without rinsing, which can also have insect repellent or insecticidal functions. [Solution] To prepare a cleaning composition containing etofenprox, a lower alcohol, and polyoxyethylene hydrogenated castor oil having an HLB of 7.0 to 14.5. Such a cleaning composition may further contain an additional nonionic surfactant and/or amphoteric surfactant. [Selected Figure] None

Description

The present invention relates to cleaning compositions for use primarily on animals, such as pets and livestock. More specifically, the present invention relates to cleaning compositions that contain etofenprox and are suitable for application in foam form.

Pests that attach to animals that interact with humans, such as pets or livestock, can transmit diseases that cause serious symptoms to these animals, or cause allergies or harmful effects to humans. be. For controlling these pests, there are known pest control agents that are mainly applied by dropping, spraying, or coating on the body surfaces of pets and livestock.

Pyrethroid compounds or combinations of pyrethroid compounds with other compounds are widely used as active ingredients in such cleaning compositions (Patent Document 1).

JP2020-007238A

In recent years, the aging of pets has progressed, and the number of households raising elderly animals such as senior dogs and cats is increasing. For such animals, there is a great need to keep the body clean and prevent damage from fleas and ticks, but owners and caregivers are struggling with how to do so. Many dogs and cats inherently dislike water, and the use of water is stressful for such individuals. In particular, ordinary shampoos that are washed away with water are a heavy burden for elderly dogs and cats. Therefore, there is a demand for a cleaning composition that can be used as a so-called dry shampoo for animals that does not use water while controlling or eliminating pests. In addition, by making it a dry shampoo, no wastewater is generated when rinsing, and domestic wastewater can be minimized, making it an environmentally friendly composition from the perspective of the SDGs.

An object of the present invention is to provide a cleaning composition that can be applied in the form of a foam to animals targeted for pest control, has a good feeling of use, and has excellent stability.

As a result of intensive studies to solve this problem, the present inventors added etofenprox, a lower alcohol, and polyoxyethylene hydrogenated castor oil with an HLB of 7.0 to 14.5, and adjusted their concentrations. The inventors have discovered that by doing so, it is possible to prepare a cleaning composition that can form a good foam upon application, and have completed the present invention.

That is, the present invention provides the following cleaning composition.
[1].
Etofenprox 0.05w/w% or more and 0.6w/w% or less;
Lower alcohol 10w/w% or more and 39w/w% or less; and polyoxyethylene hydrogenated castor oil with HLB 7.0 to 14.5 3w/w% or more and 7.5w/w% or less;
A cleaning composition containing the following, which is discharged in the form of a foam.
[2]
The cleaning composition according to [1], wherein the lower alcohol is ethanol.
[3]
The cleaning composition according to [1] or [2], further comprising a nonionic surfactant other than polyoxyethylene hydrogenated castor oil with an HLB of 7.0 to 14.5.
[4]
The cleaning composition according to any one of [1] to [3], wherein the nonionic surfactant is coconut oil fatty acid diethanolamide.
[5]
The cleaning composition according to any one of [1] to [4], further comprising an amphoteric surfactant.
[6]
Etofenprox 0.05w/w% or more and 0.6w/w% or less;
Lower alcohol 10w/w% or more and 39w/w% or less; and polyoxyethylene hydrogenated castor oil with HLB 7.0 to 14.5 3w/w% or more and 7.5w/w% or less;
A cleaning product for animals, comprising a cleaning composition containing:
[7]
The animal cleaning product according to [6], which is a dry shampoo.

The present invention provides a cleaning composition that can be formed into a good foam when applied.

In this specification, the unit of content "w/w%" is synonymous with "g/100g."

[Cleaning composition]
The cleaning composition of the present invention is a cleaning composition containing etofenprox, a lower alcohol, and polyoxyethylene hydrogenated castor oil with an HLB of 7.0 to 14.5.

(Etofenprox)
Etofenprox means 2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzyl ether.
Etofenprox can be any active stereoisomer or mixture.

In the cleaning composition of the present invention, the content of etofenprox relative to the total amount of the cleaning composition is 0.05 w/w% or more and 0.6 w/w% or less, preferably 0.1 w/w% or more and 0.45 w/w% or less, and more preferably 0.2 w/w% or more and 0.4 w/w% or less.

(Lower alcohol)
In the cleaning composition of the present invention, the cleaning effect and quick-drying property can be improved and the foam properties can be adjusted by adding a lower alcohol. Here, the lower alcohol refers to an alcohol having 1 to 5 carbon atoms, and for example, ethanol, isopropanol, or a combination thereof is preferable. As the lower alcohol, ethanol is more preferable.

In the cleaning composition of the present invention, the content of lower alcohol relative to the total amount of the cleaning composition is preferably 10 w/w% or more and 39 w/w% or less, and 12 w/w% or more and 35 w/w% or less. The following is more preferable, and 15 w/w% or more and 32 w/w% or less is even more preferable.

(Polyoxyethylene hydrogenated castor oil)
The cleaning composition of the present invention contains polyoxyethylene hydrogenated castor oil having an HLB of 7.0 to 14.5. By using such polyoxyethylene hydrogenated castor oil, the stability of the formulation can be maintained and the foam properties can be adjusted.

In the cleaning composition of the present invention, the content of polyoxyethylene hydrogenated castor oil having an HLB of 7.0 to 14.5 relative to the total amount of the cleaning composition is 3 w/w% or more and 7.5 w/w% or less, preferably 4 w/w% or more and 7.5 w/w% or less, and more preferably 5 w/w% or more and 7 w/w% or less.

(Nonionic Surfactant)
The cleaning composition of the present invention may contain, in addition to etofenprox, lower alcohol, and polyoxyethylene hydrogenated castor oil having an HLB of 7.0 to 14.5, a nonionic surfactant other than polyoxyethylene hydrogenated castor oil having an HLB of 7.0 to 14.5. Examples of such nonionic surfactants include polyoxyethylene alkyl ethers, polyoxyethylene alkylphenyl ethers, polyoxyethylene fatty acid esters, polyoxyethylene sorbitan fatty acid esters, sorbitan fatty acid esters, fatty acid monoglycerides, sucrose fatty acid esters, higher fatty acid alkanols, coconut oil fatty acid diethanolamides, fatty acid alkanolamides, and amine oxides.

Among these, although not limited, it is preferable to use, for example, coconut oil fatty acid diethanolamide.

Furthermore, the above nonionic surfactants can be used alone or in combination of two or more kinds.

In the cleaning composition of the present invention, the content of nonionic surfactants other than polyoxyethylene hydrogenated castor oil having an HLB of 7.0 to 14.5 relative to the total amount of the cleaning composition is preferably 0.01 w/w% or more and 15 w/w% or less in the cleaning composition.

(Ampholytic surfactant)
The cleaning composition of the present invention can also contain an amphoteric surfactant in addition to etofenprox, a lower alcohol, and polyoxyethylene hydrogenated castor oil having an HLB of 7.0 to 14.5. Examples of such amphoteric surfactants include, but are not limited to, amino-type or betaine-type amphoteric surfactants, sulfonic acid-type amphoteric surfactants, and sulfobetaine-type amphoteric surfactants. Among these, although not limited, fatty acid aminopropyl betaine is preferred, and aminopropyl betaine laurate is more preferred.
Furthermore, the above amphoteric surfactants can be used alone or in combination of two or more.

In the cleaning composition of the present invention, the content of the amphoteric surfactant relative to the total amount of the cleaning composition is preferably 0.01 w/w% or more and 15 w/w% or less.

(Polyhydric alcohol)
The cleaning composition of the present invention can also contain a polyhydric alcohol in addition to etofenprox, a lower alcohol, and polyoxyethylene hydrogenated castor oil having an HLB of 7.0 to 14.5. Such polyhydric alcohols include, but are not limited to, 1,3-butylene glycol, dipropylene glycol, polyethylene glycol, propylene glycol or glycerin. Among these, 1,3-butylene glycol is preferred, although it is not limited.
Furthermore, the above polyhydric alcohols can be used alone or in combination of two or more.

(component ratio)
In the cleaning composition of the present invention, the ratio of polyoxyethylene hydrogenated castor oil with an HLB of 7.0 to 14.5 to etofenprox is 5 parts by mass or more and 150 parts by mass or less per 1 part by mass of etofenprox. It is preferably 8 parts by mass or more and 100 parts by mass or less, even more preferably 10 parts by mass or more and 50 parts by mass or less, and even more preferably 12 parts by mass or more and 40 parts by mass or less.

(water)
The cleaning composition of the present invention may be a liquid composition containing water. The water may be purified water such as ion-exchanged water, ordinary tap water, industrial water, or the like.
The content of water in the total amount of the cleaning composition is preferably 40 w/w % or more and 85 w/w % or less, and more preferably 53 w/w % or more and 76 w/w % or less.

(pest)
Pests as referred to in this specification are not limited to, but particularly include fleas (including fleas that parasitize dogs, cats, etc.), mites (including ticks, chiggers, oribatid mites, scabies mites, and cat mites), or parasitic or blood-sucking pests such as lice, mosquitoes, etc. Particularly preferred pests to be controlled are fleas, mites, and mosquitoes.

(animal)
The animals of the present invention include various animals such as various pets, livestock, and poultry. In particular, pets such as dogs, cats, rabbits, and hamsters, livestock and poultry such as cows, horses, pigs, and chickens are mentioned. Of these, dogs and cats are preferred. The cleaning compositions of the present invention can be applied to, but are not limited to, senior dogs or cats (e.g., individuals over 7 years old or over 8 years old, more generally over 9 years old or over 10 years old), or sick animals. It can also be preferably used for.

(pH)
The cleaning composition of the present invention preferably has a liquid pH of 3 to 10 from the viewpoint of component stability or safety. More preferably, the cleaning composition has a pH of 4 to 8. The pH of the cleaning composition can be measured at 25° C. using a commercially available pH meter (for example, model F-52 (registered trademark) manufactured by Horiba, Ltd.).

(viscosity)
The cleaning composition of the present invention is prepared at 25°C and SPINDLE No. 1 from the viewpoint of component stability. The viscosity of M1 at 100 rpm is preferably about 0.5 to 1000 mpa·s, more preferably about 3 to 100 mpa·s. The viscosity of the cleaning composition can be measured at 25° C. using a commercially available viscometer (for example, model TVB-10M, manufactured by Toki Sangyo Co., Ltd.).

(Other ingredients)
The cleaning composition of the present invention may contain optional components as appropriate, so long as they do not impair the effects of the present invention. Examples of optional components include pest control (including insect repellent and insecticidal) components other than etofenprox, insect growth inhibitors, rinse agents, moisturizing agents, static electricity inhibitors (antistatic agents), pH adjusters, silicone compounds, chelating agents, anti-redeposition agents, polymers, preservatives, antibacterial agents, germicides, natural product extracts, dispersants, antioxidants, thickeners, viscosity reducers, stabilizers, deodorants, fragrances, and colorants.

Examples of pH adjusters include, but are not limited to, citric acid, phosphoric acid, sodium citrate, sodium phosphate, sodium bicarbonate, triethanolamine, ammonia, potassium hydroxide, sodium hydroxide, etc.

(Applications, etc.)
The cleaning composition of the present invention is a liquid composition intended to be applied in foam form. The cleaning composition of the present invention can preferably be applied to the body surface of animals such as pets, although it is not limited thereto, and is particularly suitably used widely from the entire hair surface to the hair roots. Furthermore, it can also be used on areas where there is no hair, such as the paw pads. More specifically, it can be used on the entire front paws, entire hind paws, toes, back, abdomen, head, etc. of the animal. By applying the cleaning composition of the present invention in the form of a foam, it can have the feel and ease of handling peculiar to foam. Therefore, when the foam is applied to the animal's body surface, it can also provide a good feeling of use on human hand skin. The cleaning composition of the present invention is particularly preferably used as a dry shampoo that does not rinse off. Furthermore, it can be used, for example, to remove tear stains, sebum stains, and other stains, and to care for paw pads, and can also have insect repellent and insecticidal functions.

Further, the method of using the cleaning composition of the present invention can be, for example, the following method. That is, once a day, once every 3 days, once a week, once every two weeks, once a month, apply an appropriate amount (for example, about 1 to 20 g) in the form of a foam to the entire animal's body or It can be applied only partially.

(container)
The cleaning composition of the present invention is preferably contained in a foam-discharging container. The foam-discharging container is preferably a squeeze foamer container, a pump foamer container, a trigger spray pump, or a foam-discharging aerosol container containing a propellant, and more preferably a pump foamer container. The container is provided with a porous membrane for forming foam, and foam is formed by passing the liquid cleaning composition through the porous membrane.

When the cleaning composition of the present invention is filled into a container together with a propellant, it is also possible to use a foaming aerosol container, which can directly apply the foam formed after spraying from the container to the animal's body. Carbon dioxide (carbon dioxide gas), nitrogen, liquefied petroleum gas (LPG), etc. can also be used as the propellant.

The material of the container into which the cleaning composition of the present invention is filled is not particularly limited, but examples include containers made of polyolefin resin, PET resin, acrylic resin, polyester resin, aerosol cans, aerosol resin containers, etc.

[Production method]
The cleaning composition of the present invention can be produced by mixing the raw materials by a known method, which may include a sterilization step or a filtration step, if necessary.

Next, the present invention will be specifically explained using examples, but the present invention is not limited to the following examples. Note that the unit of each component amount in the table is w/w% unless otherwise specified in the table.

The components listed in Table 1 were mixed and stirred at room temperature to obtain a cleaning composition.

[1] Properties and Stability Evaluation Test The properties of the composition were evaluated by checking the state immediately after production. Visually, a clear (or transparent) state with no insoluble matter such as crystals was rated as ○, and a state in which turbidity or insoluble matter such as crystals was observed was rated as ×. The results are shown in Table 1.

Specifically, the stability test was conducted by preparing each composition, transferring it to a 50 ml glass container, sealing the container, and allowing it to stand at 5°C. After 24 hours, the sample was taken out from the 5°C storage to room temperature, and the state of the solution at that time was visually observed. Visually, a clear (or transparent) state with no insoluble matter such as crystals was rated as ○, and a state in which turbidity or insoluble matter such as crystals was observed was rated as ×. The results are also shown in Table 1.

[2] Foaming Evaluation Test 100 ml of each composition was filled into a foaming container (100 ml capacity). The foaming container used was a pump foamer pump and a container manufactured by Yoshino Kogyosho Co., Ltd.
At room temperature and humidity, 0.9 g of each composition was dispensed and applied onto the hand. The foam that was generated was evaluated as ◯ if it was confirmed that the foam was generated and maintained for at least 5 seconds without falling off the hand, and as × if the foam was insufficient or the foam was not maintained for 5 seconds. The results are also shown in Table 1.

[3] Evaluation of Feeling in Use Each composition filled in a container in the same manner as in [2] above was applied to a test piece of fur and the condition of the fur after use was examined.
Specifically, at room temperature and humidity, about 3 g of each composition was dispensed onto a test fur (real fox fur) and applied to the entire surface by hand. After use, the composition was rated as ◯ if the fur was not dry or stiff and was in good condition, and rated as × if the fur was dry or stiff or was in poor condition. The results are shown in Table 1.

As a result of the test, the composition of the embodiment showed a clear appearance and outstanding stability both immediately after preparation and after storage at 5°C, compared to the composition of the comparative example.

Furthermore, it was found that the compositions of the examples had better foaming properties than the compositions of the comparative examples.

A test using test fur showed that the composition of the example had an excellent feel when used. In addition, the composition of the comparative example had a poor foam state and poor stability, so it was not possible to confirm the feeling of use on fur.

Claims (7)

Etofenprox 0.05 w/w% or more and 0.6 w/w% or less;
Lower alcohol: 10% w/w or more and 39% w/w or less; and Polyoxyethylene hydrogenated castor oil having an HLB of 7.0 to 14.5: 3% w/w or more and 7.5% w/w or less;
A cleaning composition comprising the above, the cleaning composition being intended to be discharged in the form of foam. The cleaning composition according to claim 1, wherein the lower alcohol is ethanol. The cleaning composition according to claim 1, further comprising a nonionic surfactant other than polyoxyethylene hydrogenated castor oil with an HLB of 7.0 to 14.5. The cleaning composition according to claim 3, wherein the nonionic surfactant is coconut oil fatty acid diethanolamide. The cleaning composition according to claim 1, further comprising an amphoteric surfactant. Etofenprox 0.05w/w% or more and 0.6w/w% or less;
Lower alcohol 10w/w% or more and 39w/w% or less; and polyoxyethylene hydrogenated castor oil with HLB 7.0 to 14.5 3w/w% or more and 7.5w/w% or less;
A cleaning product for animals, comprising a cleaning composition containing: 7. The animal cleaning product of claim 6 which is a dry shampoo.