JP2023552862A - ピリド［２，３－ｄ］イミダゾール誘導体、および皮膚疾患の処置のためのｉｔｋの阻害剤としてのそれらの使用 - Google Patents

ピリド［２，３－ｄ］イミダゾール誘導体、および皮膚疾患の処置のためのｉｔｋの阻害剤としてのそれらの使用 Download PDF

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JP2023552862A
JP2023552862A JP2023535824A JP2023535824A JP2023552862A JP 2023552862 A JP2023552862 A JP 2023552862A JP 2023535824 A JP2023535824 A JP 2023535824A JP 2023535824 A JP2023535824 A JP 2023535824A JP 2023552862 A JP2023552862 A JP 2023552862A
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methyl
mmol
mixture
pharmaceutically acceptable
preparation
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JP2023552862A5 (enExample
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ウィリアム ベーグレイ スコット
カシミロ－ガルシア アグスティン
エリザベス デヴォーレン ジェニファー
アルドリン デニー ラージャ
スティーブン ゲルステンベルガー ブライアン
リン リー キャサリン
エルドリッジ ラヴァーイング フランク
ディネシュクマール パリーク ミハイル
ウォルター ストローバック ジョセフ
イシドロ トゥルヒージョ ジョン
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ファイザー・インク
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2023535824A 2020-12-15 2021-12-13 ピリド［２，３－ｄ］イミダゾール誘導体、および皮膚疾患の処置のためのｉｔｋの阻害剤としてのそれらの使用 Pending JP2023552862A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063125671P 2020-12-15 2020-12-15
US63/125,671 2020-12-15
PCT/IB2021/061645 WO2022130175A1 (en) 2020-12-15 2021-12-13 Pyrido[2,3-d]imidazole derivatives and their use as inhibitors of itk for the teatment of skin disease

Publications (2)

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JP2023552862A true JP2023552862A (ja) 2023-12-19
JP2023552862A5 JP2023552862A5 (enExample) 2024-11-06

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JP2023535824A Pending JP2023552862A (ja) 2020-12-15 2021-12-13 ピリド［２，３－ｄ］イミダゾール誘導体、および皮膚疾患の処置のためのｉｔｋの阻害剤としてのそれらの使用

Country Status (5)

Country Link
US (1) US20240124439A1 (enExample)
EP (1) EP4263538A1 (enExample)
JP (1) JP2023552862A (enExample)
CA (1) CA3205023A1 (enExample)
WO (1) WO2022130175A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3205020A1 (en) * 2020-12-15 2022-06-23 Pfizer Inc. Benzimidazole derivatives and their use as inhibitors of itk for the treatment of skin disease
WO2024123175A1 (en) 2022-12-06 2024-06-13 Erasmus University Medical Center Rotterdam Compositions for treating immune checkpoint blockade therapy resistant cancers

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004016270A1 (en) * 2002-08-14 2004-02-26 Astrazeneca Ab USE OF Itk INHIBITORS FOR THE TREATMENT OF MAST CELL-DRIVEN OR BASOPHIL-DRIVEN DISEASES
JP2005509633A (ja) * 2001-10-26 2005-04-14 アベンティス・ファーマスーティカルズ・インコーポレイテツド ベンゾイミダゾールおよび類縁体および蛋白キナーゼ阻害剤としてのその使用
JP2011132222A (ja) * 2009-11-25 2011-07-07 Japan Tobacco Inc インドール化合物及びその医薬用途
WO2013026201A1 (zh) * 2011-08-24 2013-02-28 厦门硅田系统工程有限公司 新型rfid标签微能量采集控制装置
WO2014041518A1 (en) * 2012-09-14 2014-03-20 Glenmark Pharmaceuticals S.A. Thienopyrrole derivatives as itk inhibitors
WO2016010108A1 (ja) * 2014-07-18 2016-01-21 塩野義製薬株式会社 含窒素複素環誘導体およびそれらを含有する医薬組成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2287971T3 (es) 1997-08-11 2007-12-16 Pfizer Products Inc. Dispersiones farmaceuticas solidas con biodisponibilidad incrementada.
WO2013026021A2 (en) * 2011-08-18 2013-02-21 Buck Institute For Research On Aging Trka as a target for inhibiting app cleavage and/or progression of alzheimer's disease

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005509633A (ja) * 2001-10-26 2005-04-14 アベンティス・ファーマスーティカルズ・インコーポレイテツド ベンゾイミダゾールおよび類縁体および蛋白キナーゼ阻害剤としてのその使用
WO2004016270A1 (en) * 2002-08-14 2004-02-26 Astrazeneca Ab USE OF Itk INHIBITORS FOR THE TREATMENT OF MAST CELL-DRIVEN OR BASOPHIL-DRIVEN DISEASES
JP2011132222A (ja) * 2009-11-25 2011-07-07 Japan Tobacco Inc インドール化合物及びその医薬用途
WO2013026201A1 (zh) * 2011-08-24 2013-02-28 厦门硅田系统工程有限公司 新型rfid标签微能量采集控制装置
WO2014041518A1 (en) * 2012-09-14 2014-03-20 Glenmark Pharmaceuticals S.A. Thienopyrrole derivatives as itk inhibitors
WO2016010108A1 (ja) * 2014-07-18 2016-01-21 塩野義製薬株式会社 含窒素複素環誘導体およびそれらを含有する医薬組成物

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CA3205023A1 (en) 2022-06-23
US20240124439A1 (en) 2024-04-18
EP4263538A1 (en) 2023-10-25
WO2022130175A1 (en) 2022-06-23

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