JP2023546453A - 眼障害を処置するための化合物および方法 - Google Patents
眼障害を処置するための化合物および方法 Download PDFInfo
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- JP2023546453A JP2023546453A JP2023524276A JP2023524276A JP2023546453A JP 2023546453 A JP2023546453 A JP 2023546453A JP 2023524276 A JP2023524276 A JP 2023524276A JP 2023524276 A JP2023524276 A JP 2023524276A JP 2023546453 A JP2023546453 A JP 2023546453A
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- substituted
- alkyl
- radical
- heteroalkyl
- pharmaceutically acceptable
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- 229960004889 salicylic acid Drugs 0.000 description 1
- 229960004499 scopolamine hydrobromide Drugs 0.000 description 1
- WTGQALLALWYDJH-MOUKNHLCSA-N scopolamine hydrobromide (anhydrous) Chemical compound Br.C1([C@@H](CO)C(=O)O[C@H]2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 WTGQALLALWYDJH-MOUKNHLCSA-N 0.000 description 1
- 229940116351 sebacate Drugs 0.000 description 1
- CXMXRPHRNRROMY-UHFFFAOYSA-L sebacate(2-) Chemical compound [O-]C(=O)CCCCCCCCC([O-])=O CXMXRPHRNRROMY-UHFFFAOYSA-L 0.000 description 1
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- 150000003335 secondary amines Chemical class 0.000 description 1
- 229940065287 selenium compound Drugs 0.000 description 1
- 150000003343 selenium compounds Chemical class 0.000 description 1
- 229910000338 selenium disulfide Inorganic materials 0.000 description 1
- JNMWHTHYDQTDQZ-UHFFFAOYSA-N selenium sulfide Chemical compound S=[Se]=S JNMWHTHYDQTDQZ-UHFFFAOYSA-N 0.000 description 1
- 229960005265 selenium sulfide Drugs 0.000 description 1
- 150000003346 selenoethers Chemical class 0.000 description 1
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- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 208000015891 sexual disease Diseases 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
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- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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US202063094793P | 2020-10-21 | 2020-10-21 | |
US63/094,793 | 2020-10-21 | ||
US202163170988P | 2021-04-05 | 2021-04-05 | |
US63/170,988 | 2021-04-05 | ||
PCT/IB2021/000707 WO2022084738A2 (en) | 2020-10-21 | 2021-10-20 | Compounds and methods for the treatment of ocular disorders |
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JP2023546453A true JP2023546453A (ja) | 2023-11-02 |
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JP2023524276A Pending JP2023546453A (ja) | 2020-10-21 | 2021-10-20 | 眼障害を処置するための化合物および方法 |
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EP (1) | EP4232149A2 (ko) |
JP (1) | JP2023546453A (ko) |
KR (1) | KR20230110515A (ko) |
AU (1) | AU2021363702A1 (ko) |
CA (1) | CA3196145A1 (ko) |
IL (1) | IL302173A (ko) |
MX (1) | MX2023004537A (ko) |
WO (1) | WO2022084738A2 (ko) |
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JP2022530322A (ja) | 2019-04-18 | 2022-06-29 | アズーラ オフサルミックス エルティーディー. | 眼障害を処置するための化合物および方法 |
US11459351B1 (en) | 2021-04-05 | 2022-10-04 | Azura Ophthalmics Ltd. | Compounds and methods for the treatment of ocular disorders |
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WO2003070173A2 (en) * | 2002-02-15 | 2003-08-28 | Sympore Gmbh | Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof |
CN114007625A (zh) * | 2019-04-18 | 2022-02-01 | 阿祖拉眼科有限公司 | 用于治疗眼病的化合物和方法 |
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2021
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- 2021-10-20 KR KR1020237016470A patent/KR20230110515A/ko unknown
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- 2021-10-20 IL IL302173A patent/IL302173A/en unknown
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- 2021-10-20 EP EP21882226.0A patent/EP4232149A2/en active Pending
- 2021-10-20 CA CA3196145A patent/CA3196145A1/en active Pending
- 2021-10-20 MX MX2023004537A patent/MX2023004537A/es unknown
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IL302173A (en) | 2023-06-01 |
EP4232149A2 (en) | 2023-08-30 |
AU2021363702A9 (en) | 2024-02-08 |
WO2022084738A3 (en) | 2022-06-30 |
CA3196145A1 (en) | 2022-04-28 |
MX2023004537A (es) | 2023-06-15 |
KR20230110515A (ko) | 2023-07-24 |
WO2022084738A2 (en) | 2022-04-28 |
AU2021363702A1 (en) | 2023-06-15 |
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