JP2023544797A5 - - Google Patents

Info

Publication number
JP2023544797A5
JP2023544797A5 JP2023521295A JP2023521295A JP2023544797A5 JP 2023544797 A5 JP2023544797 A5 JP 2023544797A5 JP 2023521295 A JP2023521295 A JP 2023521295A JP 2023521295 A JP2023521295 A JP 2023521295A JP 2023544797 A5 JP2023544797 A5 JP 2023544797A5
Authority
JP
Japan
Prior art keywords
days
pharmaceutical composition
approximately
hours
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023521295A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023544797A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/053759 external-priority patent/WO2022076549A1/en
Publication of JP2023544797A publication Critical patent/JP2023544797A/ja
Publication of JP2023544797A5 publication Critical patent/JP2023544797A5/ja
Pending legal-status Critical Current

Links

JP2023521295A 2020-10-07 2021-10-06 脈絡膜上投与用の、高粘度製剤などの製剤 Pending JP2023544797A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063088826P 2020-10-07 2020-10-07
US63/088,826 2020-10-07
US202163147527P 2021-02-09 2021-02-09
US63/147,527 2021-02-09
PCT/US2021/053759 WO2022076549A1 (en) 2020-10-07 2021-10-06 Formulations for suprachoroidal administration such as high viscosity formulations

Publications (2)

Publication Number Publication Date
JP2023544797A JP2023544797A (ja) 2023-10-25
JP2023544797A5 true JP2023544797A5 (https=) 2024-03-06

Family

ID=78516913

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023521295A Pending JP2023544797A (ja) 2020-10-07 2021-10-06 脈絡膜上投与用の、高粘度製剤などの製剤

Country Status (8)

Country Link
US (1) US20240024508A1 (https=)
EP (1) EP4225270A1 (https=)
JP (1) JP2023544797A (https=)
AU (1) AU2021358048A1 (https=)
CA (1) CA3198372A1 (https=)
MX (1) MX2023004035A (https=)
TW (1) TW202228648A (https=)
WO (1) WO2022076549A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3727468A4 (en) 2017-12-19 2021-09-22 Akouos, Inc. AAV-MEDIATED THERAPEUTIC ANTIBODIES DELIVERY TO THE INTERNAL EAR
EP3886946A1 (en) 2019-06-05 2021-10-06 Regeneron Pharmaceuticals, Inc. Devices and methods for precision dose delivery
IL303317A (en) 2020-12-01 2023-07-01 Akouos Inc ANTI-NATURAL ANTIBODY STRUCTURES AND RELATED METHODS FOR THE TREATMENT OF SYMPTOMS ASSOCIATED WITH VESTIBULAR SWANNOMA
TW202345913A (zh) * 2022-04-06 2023-12-01 美商銳進科斯生物股份有限公司 用於脈絡膜上投與之調配物諸如凝膠調配物
IL319873A (en) 2022-09-30 2025-05-01 Regenxbio Inc Treatment of eye diseases with recombinant viral vectors containing anti-VEGF FAB
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device
WO2024238867A1 (en) 2023-05-16 2024-11-21 Regenxbio Inc. Vectorized anti-complement antibodies and administration thereof
TW202548025A (zh) 2024-04-08 2025-12-16 美商銳進科斯生物股份有限公司 載體化抗補體抗體與補體劑及其投與

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2379166C (en) 1999-08-09 2013-03-26 Targeted Genetics Corporation Enhancement of expression of a single-stranded, heterologous nucleotide sequence from recombinant viral vectors by designing the sequence such that it forms instrastrand base pairs
MX359371B (es) 2001-11-13 2018-09-25 Univ Pennsylvania Un metodo para detectar y/o identificar secuencias del virus adeno-asociado y aislamiento de secuencias novedosas identificadas de ese modo.
PT1453547T (pt) 2001-12-17 2016-12-28 Univ Pennsylvania Sequências do vírus adeno-associado (aav) do serotipo 8, vetores contendo as mesmas, e utilizações destas
EP2345731B1 (en) 2003-09-30 2015-10-21 The Trustees of the University of Pennsylvania Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof
ES2525067T3 (es) 2005-04-07 2014-12-17 The Trustees Of The University Of Pennsylvania Método de incremento de la función de un vector de AAV
JP4495210B2 (ja) 2005-06-09 2010-06-30 パナソニック株式会社 振幅誤差補償装置及び直交度誤差補償装置
US8734809B2 (en) 2009-05-28 2014-05-27 University Of Massachusetts AAV's and uses thereof
US8927514B2 (en) 2010-04-30 2015-01-06 City Of Hope Recombinant adeno-associated vectors for targeted treatment
US8628966B2 (en) 2010-04-30 2014-01-14 City Of Hope CD34-derived recombinant adeno-associated vectors for stem cell transduction and systemic therapeutic gene transfer
WO2012057363A1 (ja) 2010-10-27 2012-05-03 学校法人自治医科大学 神経系細胞への遺伝子導入のためのアデノ随伴ウイルスビリオン
WO2012109570A1 (en) 2011-02-10 2012-08-16 The University Of North Carolina At Chapel Hill Viral vectors with modified transduction profiles and methods of making and using the same
CN105755044A (zh) 2011-04-22 2016-07-13 加利福尼亚大学董事会 具有变异衣壳的腺相关病毒病毒体及其使用方法
ES2857773T5 (es) 2011-08-24 2024-06-04 Univ Leland Stanford Junior Nuevas proteínas de la cápside de AAV para la transferencia de ácidos nucleicos
WO2013170078A1 (en) 2012-05-09 2013-11-14 Oregon Health & Science University Adeno associated virus plasmids and vectors
CA2905952A1 (en) 2013-03-13 2014-10-02 The Children's Hospital Of Philadelphia Adeno-associated virus vectors and methods of use thereof
ES2739288T3 (es) 2013-09-13 2020-01-30 California Inst Of Techn Recuperación selectiva
CN106232618A (zh) 2013-10-11 2016-12-14 马萨诸塞眼科耳科诊所 预测祖先病毒序列的方法及其用途
WO2015164757A1 (en) 2014-04-25 2015-10-29 Oregon Health & Science University Methods of viral neutralizing antibody epitope mapping
CN107249522B (zh) 2014-09-19 2021-04-20 奥叙拉尔有限公司 眼科递送装置
KR20240005973A (ko) 2016-04-15 2024-01-12 리젠엑스바이오 인크. 완전히-인간형의 번역후 변형된 항-VEGF Fab를 이용한 눈 질환의 치료
US10912883B2 (en) 2017-11-04 2021-02-09 Altaviz, Llc Gas-powered fluid injection system

Similar Documents

Publication Publication Date Title
JP7733706B2 (ja) 血管新生眼疾患を処置するためのvegfアンタゴニストの使用
JP2023544797A5 (https=)
US20240024508A1 (en) Formulations for suprachoroidal administration such as high viscosity formulations
US20230414788A1 (en) Formulations for suprachoroidal administration such as gel formulations
US20230372538A1 (en) Formulations for suprachoroidal administration such as formulations with aggregate formation
EP4027983B1 (en) Treatment of ocular neovascular diseases using aav2 variants encoding aflibercept
TW202117016A (zh) 使用編碼阿柏西普(aflibercept)之aav2變異體治療眼睛新生血管性疾病的方法
KR20240145489A (ko) 아플리베르셉트를 코딩하는 aav2 변이체를 사용하여 안구 신생혈관 질환을 치료하는 방법
EP4682163A2 (en) Method of reducing cst fluctuation in neovascular amd by a recombinant adeno-associated virus
US20250339555A1 (en) Formulations for suprachoroidal administration such as formulations with aggregate formation
JP2024148177A (ja) アフリベルセプトをコードするaav2バリアントを使用する眼内血管新生疾患を処置する方法
US20260034243A1 (en) Pharmaceutical composition comprising a recombinant adeno-associated virus vector with an expression cassette encoding a transgene for suprachoroidal administration
CN116546975A (zh) 用于脉络膜上施用的制剂诸如高粘度制剂
CN116635004A (zh) 用于脉络膜上施用的制剂如凝胶制剂
CN116601299A (zh) 用于脉络膜上施用的制剂诸如具有聚集体形成的制剂
WO2023196835A1 (en) Formulations for suprachoroidal administration such as gel formulations
HK40130210A (en) Method of reducing cst fluctuation in neovascular amd by a recombinant adeno-associated virus