JP2023541639A5 - - Google Patents
Info
- Publication number
- JP2023541639A5 JP2023541639A5 JP2023516798A JP2023516798A JP2023541639A5 JP 2023541639 A5 JP2023541639 A5 JP 2023541639A5 JP 2023516798 A JP2023516798 A JP 2023516798A JP 2023516798 A JP2023516798 A JP 2023516798A JP 2023541639 A5 JP2023541639 A5 JP 2023541639A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- acid acyl
- linker
- acyl conjugate
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063079179P | 2020-09-16 | 2020-09-16 | |
| US63/079,179 | 2020-09-16 | ||
| PCT/EP2021/075386 WO2022058386A1 (en) | 2020-09-16 | 2021-09-15 | Oligonucleotides conjugated to fatty acids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023541639A JP2023541639A (ja) | 2023-10-03 |
| JP2023541639A5 true JP2023541639A5 (https=) | 2024-09-24 |
Family
ID=77989771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023516798A Pending JP2023541639A (ja) | 2020-09-16 | 2021-09-15 | 脂肪酸にコンジュゲートしたオリゴヌクレオチド |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20250270248A1 (https=) |
| EP (1) | EP4213883A1 (https=) |
| JP (1) | JP2023541639A (https=) |
| CN (1) | CN116133691A (https=) |
| WO (1) | WO2022058386A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023039522A1 (en) * | 2021-09-10 | 2023-03-16 | Guardian Therapeutics, Llc | Fatty acid conjugates of nucleic acids |
| WO2025054459A1 (en) * | 2023-09-08 | 2025-03-13 | Dicerna Pharmaceuticals, Inc. | Rnai oligonucleotide conjugates |
| AU2024353921A1 (en) * | 2023-09-27 | 2026-04-16 | Neuro3 Therapeutics (Suzhou) Ltd. | Novel sirna constructs, therapeutics, and modifications |
| WO2025250382A1 (en) * | 2024-05-31 | 2025-12-04 | University Of Rochester | Method and compositions for aptamer mediated delivery of therapeutics |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210052631A1 (en) * | 2015-09-25 | 2021-02-25 | Ionis Pharmaceuticals, Inc. | Conjugated antisense compounds and their use |
| KR20190123351A (ko) * | 2017-03-22 | 2019-10-31 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 개질된 올리고뉴클레오티드 및 이의 치료 용도 |
| JP7665509B2 (ja) * | 2018-05-11 | 2025-04-21 | アルファ アノマリック エスアエス | ７’－５’－アルファ－アノマー二環式糖ヌクレオシドを含むオリゴヌクレオチドコンジュゲート |
| WO2021046497A2 (en) * | 2019-09-06 | 2021-03-11 | Shen Haifa | Orally delivered therapeutical composition and use thereof |
-
2021
- 2021-09-15 WO PCT/EP2021/075386 patent/WO2022058386A1/en not_active Ceased
- 2021-09-15 CN CN202180062514.8A patent/CN116133691A/zh active Pending
- 2021-09-15 EP EP21782452.3A patent/EP4213883A1/en active Pending
- 2021-09-15 JP JP2023516798A patent/JP2023541639A/ja active Pending
- 2021-09-15 US US18/245,422 patent/US20250270248A1/en active Pending
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