JP2023537982A - フィターゼ変異体及びそれをコードするポリヌクレオチド - Google Patents

フィターゼ変異体及びそれをコードするポリヌクレオチド Download PDF

Info

Publication number
JP2023537982A
JP2023537982A JP2023509774A JP2023509774A JP2023537982A JP 2023537982 A JP2023537982 A JP 2023537982A JP 2023509774 A JP2023509774 A JP 2023509774A JP 2023509774 A JP2023509774 A JP 2023509774A JP 2023537982 A JP2023537982 A JP 2023537982A
Authority
JP
Japan
Prior art keywords
phytase
seq
polypeptide
variant
identity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023509774A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023537982A5 (https=
Inventor
ビン イェスパ
コウウレー スコウ ラース
ホンシアオ チャイ
チエン チャン
サンティゴサ エステル
ソルバラ ジョゼ－オタビオ
アンヌ カトリーヌ シャルロット セオン オレリア
ルイーズ ウォーク キャリー
Original Assignee
ノボザイムス アクティーゼルスカブ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ノボザイムス アクティーゼルスカブ filed Critical ノボザイムス アクティーゼルスカブ
Publication of JP2023537982A publication Critical patent/JP2023537982A/ja
Publication of JP2023537982A5 publication Critical patent/JP2023537982A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/14—Pretreatment of feeding-stuffs with enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/20—Animal feeding-stuffs from material of animal origin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/20—Animal feeding-stuffs from material of animal origin
    • A23K10/22—Animal feeding-stuffs from material of animal origin from fish
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A23K20/147—Polymeric derivatives, e.g. peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/174—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/20—Inorganic substances, e.g. oligoelements
    • A23K20/30—Oligoelements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/25—Shaping or working-up of animal feeding-stuffs by extrusion
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/30—Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03008—3-Phytase (3.1.3.8)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81—Aquaculture, e.g. of fish
    • Y02A40/818—Alternative feeds for fish, e.g. in aquacultures

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Husbandry (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Birds (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Insects & Arthropods (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
JP2023509774A 2020-08-13 2021-08-13 フィターゼ変異体及びそれをコードするポリヌクレオチド Pending JP2023537982A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP20190917.3 2020-08-13
EP20190917 2020-08-13
EP20201328 2020-10-12
EP20201328.0 2020-10-12
CNPCT/CN2021/081613 2021-03-18
CN2021081613 2021-03-18
EP21172706.0 2021-05-07
EP21172706 2021-05-07
PCT/EP2021/072591 WO2022034211A1 (en) 2020-08-13 2021-08-13 Phytase variants and polynucleotides encoding same

Publications (2)

Publication Number Publication Date
JP2023537982A true JP2023537982A (ja) 2023-09-06
JP2023537982A5 JP2023537982A5 (https=) 2024-08-26

Family

ID=77666470

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023509774A Pending JP2023537982A (ja) 2020-08-13 2021-08-13 フィターゼ変異体及びそれをコードするポリヌクレオチド

Country Status (11)

Country Link
US (2) US12037613B2 (https=)
EP (1) EP4196575A1 (https=)
JP (1) JP2023537982A (https=)
KR (1) KR20230050402A (https=)
AU (1) AU2021324389A1 (https=)
BR (1) BR112023002578A2 (https=)
CA (1) CA3189083A1 (https=)
CL (3) CL2023000385A1 (https=)
MX (1) MX2023001397A (https=)
PE (1) PE20231568A1 (https=)
WO (1) WO2022034211A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4536009A1 (en) * 2022-06-08 2025-04-16 DSM IP Assets B.V. Means and methods for reducing phosphorus secretion by fish
JP7850115B2 (ja) * 2023-09-15 2026-04-22 セトラスホールディングス株式会社 きのこ培養基用添加剤及びきのこ培養基の製造方法
WO2025217017A1 (en) 2024-04-08 2025-10-16 Novozymes A/S Compositions and methods for increasing phosphorous availability

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011117396A2 (en) * 2010-03-26 2011-09-29 Novozymes A/S Thermostable phytase variants

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ237549A (en) 1990-03-23 1993-06-25 Gist Brocades Nv Production of enhanced levels of enzymes in the seeds of transgenic plants and the use of these seeds
US6395966B1 (en) 1990-08-09 2002-05-28 Dekalb Genetics Corp. Fertile transgenic maize plants containing a gene encoding the pat protein
FI932561L (fi) 1990-12-05 1993-06-04 Novo Nordisk As Proteiner med foeraendrade epitoper och foerfaranden foer deras framstaellning
DK91192D0 (da) 1992-07-10 1992-07-10 Novo Nordisk As Protein
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
DE4422198C2 (de) 1994-06-24 1997-08-28 Audi Ag Verfahren zum Steuern der elektrischen Beheizung eines Katalysators
CN101659926A (zh) 1994-06-30 2010-03-03 诺沃奇梅兹有限公司 非毒性、非产毒性、非致病性镰孢属表达系统及所用启动子和终止子
WO1996016177A1 (en) 1994-11-24 1996-05-30 Novo Nordisk A/S A process for producing polypeptides with reduced allergenicity
FI972443A7 (fi) 1994-12-07 1997-06-09 Novozymes As Polypeptidi, jonka allergeenisuus on vähentynyt
CN1159208A (zh) 1995-07-28 1997-09-10 吉斯特·布罗卡迪斯股份有限公司 盐稳定化酶制剂
CA2277618A1 (en) 1997-01-10 1998-07-16 Novo Nordisk A/S Enzyme coupled with polymeric molecules for skin care
JP2001511162A (ja) 1997-02-06 2001-08-07 ノボ ノルディスク アクティーゼルスカブ 付加され、そして／又は除去された付着基を有するポリペプチド−ポリマー結合体
GB2340834B (en) 1997-06-04 2001-06-06 Dsm Nv High-activity phytase compositions
ATE375387T1 (de) 1997-06-25 2007-10-15 Novozymes As Modifiziertes polypeptid
NZ330940A (en) 1997-07-24 2000-02-28 F Production of consensus phytases from fungal origin using computer programmes
EP1117771B1 (en) 1998-10-02 2003-04-23 Novozymes A/S Solid phytase compositions
AU6078899A (en) 1998-10-13 2000-05-01 Novozymes A/S A modified polypeptide with reduced immune response
ATE365210T1 (de) 1998-10-30 2007-07-15 Novozymes As Glykosylierte proteine mit reduzierter allergenität
ES2220114T3 (es) 1998-10-30 2004-12-01 Novozymes A/S Variantes de proteinas poco alergenicas.
DE19922753A1 (de) 1999-05-18 2000-11-23 Basf Ag Enzym-Instantformulierungen für die Tierernährung
DE19929257A1 (de) 1999-06-25 2000-12-28 Basf Ag Polymerbeschichtete, granulierte enzymhaltige Futtermittelzusätze und Verfahren zu deren Herstellung
FR2798049B1 (fr) 1999-09-08 2001-12-21 Marcel Tardeglio Siege obtenu par pliage de materiau
CA2395266C (en) 2000-02-08 2009-04-14 F. Hoffmann-La Roche Ag Use of acid-stable subtilisin proteases in animal feed
EP1259630A1 (en) 2000-02-23 2002-11-27 Novozymes A/S Fermentation with a phytase
EP1280817A2 (en) 2000-04-28 2003-02-05 Novozymes A/S Production and use of protein variants having modified immunogenecity
US7151204B2 (en) 2001-01-09 2006-12-19 Monsanto Technology Llc Maize chloroplast aldolase promoter compositions and methods for use thereof
WO2002090384A2 (en) 2001-05-04 2002-11-14 Novozymes A/S Antimicrobial polypeptide from aspergillus niger
EP1448595B1 (en) 2001-11-20 2006-10-18 Novozymes A/S Antimicrobial polypeptides from pseudoplectania nigrella
AU2002349297A1 (en) 2001-12-03 2003-06-17 Kobenhavns Amt Statin-like compounds
US7442398B2 (en) 2003-03-25 2008-10-28 Republic Of National Fisheries Research And Development Institute Phytase produced from Citrobacter braakii
DK2258209T3 (da) 2004-09-27 2015-08-31 Novozymes As Phytasegranuler i dyrefoder
EP1797178B1 (en) 2004-10-04 2012-09-12 DuPont Nutrition Biosciences ApS Citrobacter freundii phytase and homologues
AR050895A1 (es) 2004-10-04 2006-11-29 Novozymes As Polipeptidos que tienen actividad de fitasa y polinucleotidos que los codifican
GB0422052D0 (en) 2004-10-04 2004-11-03 Dansico As Enzymes
MX2008012632A (es) 2006-04-04 2008-10-13 Novozymes As Variantes de fitasa.
ES2577430T3 (es) 2006-08-07 2016-07-14 Novozymes A/S Gránulos de enzima para pienso para animales
ES2636369T3 (es) 2008-09-26 2017-10-05 Novozymes A/S Variantes de fitasa de Hafnia
CA2794244C (en) 2010-03-26 2019-03-12 Novozymes A/S Thermostable phytase variants
CA2794113A1 (en) 2010-03-26 2011-09-29 Novozymes A/S Thermostable phytase variants
AR084894A1 (es) 2011-02-18 2013-07-10 Danisco Composicion de aditivo para pienso
EP4501130A3 (en) 2017-09-01 2025-04-23 Novozymes A/S Animal feed additives comprising a polypeptide having protease activity and uses thereof
CN118440920A (zh) 2018-05-30 2024-08-06 南京百斯杰生物工程有限公司 植酸酶突变体
US10995325B2 (en) 2019-03-21 2021-05-04 Fornia Biosolutions, Inc. Additional phytase variants and methods
CN110724676B (zh) 2019-10-21 2021-09-07 广东溢多利生物科技股份有限公司 一种植酸酶突变体及其载体与应用

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011117396A2 (en) * 2010-03-26 2011-09-29 Novozymes A/S Thermostable phytase variants

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
野菜 - WIKIPEDIA［ONLINE], vol. 2020年6月23日保存［2025年10月10日 検索］, JPN6025043372, ISSN: 0005717771 *

Also Published As

Publication number Publication date
AU2021324389A1 (en) 2023-02-02
PE20231568A1 (es) 2023-10-04
CL2024002694A1 (es) 2025-04-11
KR20230050402A (ko) 2023-04-14
BR112023002578A2 (pt) 2023-03-14
MX2023001397A (es) 2023-03-03
CA3189083A1 (en) 2022-02-17
US20240360426A1 (en) 2024-10-31
EP4196575A1 (en) 2023-06-21
WO2022034211A1 (en) 2022-02-17
US20220049230A1 (en) 2022-02-17
CL2024002358A1 (es) 2025-01-17
CL2023000385A1 (es) 2023-09-29
US12037613B2 (en) 2024-07-16

Similar Documents

Publication Publication Date Title
EP2001999B1 (en) Phytase variants
US8206962B2 (en) Hafnia phytase variants
CA3105079C (en) Thermostable phytase variants
EP2553091B1 (en) Thermostable phytase variants
US9173421B2 (en) Thermostable phytase variants
US20240360426A1 (en) Phytase Variants and Polynucleotides Encoding Same
CN116209766A (zh) 植酸酶变体和编码其的多核苷酸

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20240809

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20240809

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20251028

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20260109

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20260428