JP2023535595A5 - - Google Patents

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Publication number
JP2023535595A5
JP2023535595A5 JP2023505376A JP2023505376A JP2023535595A5 JP 2023535595 A5 JP2023535595 A5 JP 2023535595A5 JP 2023505376 A JP2023505376 A JP 2023505376A JP 2023505376 A JP2023505376 A JP 2023505376A JP 2023535595 A5 JP2023535595 A5 JP 2023535595A5
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JP
Japan
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JP2023505376A
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Japanese (ja)
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JP2023535595A (ja
JP7832924B2 (ja
JPWO2022023450A5 (https=
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Priority claimed from PCT/EP2021/071219 external-priority patent/WO2022023450A1/en
Publication of JP2023535595A publication Critical patent/JP2023535595A/ja
Publication of JP2023535595A5 publication Critical patent/JP2023535595A5/ja
Publication of JPWO2022023450A5 publication Critical patent/JPWO2022023450A5/ja
Application granted granted Critical
Publication of JP7832924B2 publication Critical patent/JP7832924B2/ja
Active legal-status Critical Current
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JP2023505376A 2020-07-28 2021-07-28 縮合二環式raf阻害剤のキラル合成 Active JP7832924B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063057531P 2020-07-28 2020-07-28
US63/057,531 2020-07-28
PCT/EP2021/071219 WO2022023450A1 (en) 2020-07-28 2021-07-28 Chiral synthesis of fused bicyclic raf inhibitors

Publications (4)

Publication Number Publication Date
JP2023535595A JP2023535595A (ja) 2023-08-18
JP2023535595A5 true JP2023535595A5 (https=) 2024-08-06
JPWO2022023450A5 JPWO2022023450A5 (https=) 2024-08-06
JP7832924B2 JP7832924B2 (ja) 2026-03-18

Family

ID=77564067

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023505376A Active JP7832924B2 (ja) 2020-07-28 2021-07-28 縮合二環式raf阻害剤のキラル合成

Country Status (10)

Country Link
US (2) US20220041595A1 (https=)
EP (1) EP4188923A1 (https=)
JP (1) JP7832924B2 (https=)
KR (1) KR20230058630A (https=)
CN (1) CN116348465B (https=)
AU (1) AU2021318923A1 (https=)
CA (1) CA3187393A1 (https=)
IL (1) IL300110A (https=)
MX (1) MX2023001274A (https=)
WO (1) WO2022023450A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023535790A (ja) 2020-07-28 2023-08-21 ジャズ ファーマシューティカルズ アイルランド リミテッド 縮合二環式raf阻害薬及びその使用方法
CN114921508B (zh) * 2022-07-22 2022-10-11 常熟药明康德新药开发有限公司 (r)-6-羟基色满-3-羧酸的生物催化制备方法
JP2025539426A (ja) 2022-11-29 2025-12-05 ジャズ ファーマシューティカルズ アイルランド リミテッド (s)-5-((3-(4-(4-フルオロフェニル)-1h-イミダゾール-2-イル)クロマン-6-イル)オキシ)-3,4-ジヒドロ-1,8-ナフチリジン-2(1h)-オンの結晶形態
EP4665725A2 (en) * 2023-02-17 2025-12-24 Jazz Pharmaceuticals Ireland Limited Methods of treating solid tumors with mitogen activated protein kinase (mapk) pathway alterations

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DE3611229A1 (de) 1986-04-04 1987-10-08 Basf Ag Verfahren zur herstellung von feinverteilten, pulverfoermigen carotinoidpraeparaten
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