JP2023528220A - がんを含む加齢関連疾患の治療法として使用するためのミトコンドリア由来ペプチドおよびそのアナログ - Google Patents

がんを含む加齢関連疾患の治療法として使用するためのミトコンドリア由来ペプチドおよびそのアナログ Download PDF

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JP2023528220A
JP2023528220A JP2022569147A JP2022569147A JP2023528220A JP 2023528220 A JP2023528220 A JP 2023528220A JP 2022569147 A JP2022569147 A JP 2022569147A JP 2022569147 A JP2022569147 A JP 2022569147A JP 2023528220 A JP2023528220 A JP 2023528220A
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mitochondrial
cancer
seq
peptide
nosh
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JP2023528220A5 (https=
Inventor
ピンカス コーエン
ケルビン イェン
ス－ジョン キム
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ユニバーシティ オブ サザン カリフォルニア
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2022569147A 2020-05-15 2021-05-14 がんを含む加齢関連疾患の治療法として使用するためのミトコンドリア由来ペプチドおよびそのアナログ Pending JP2023528220A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063025495P 2020-05-15 2020-05-15
US63/025,495 2020-05-15
PCT/US2021/032641 WO2021231988A2 (en) 2020-05-15 2021-05-14 Mitochondrial-derived peptides and analogs thereof for use as a therapy for age-related diseases including cancer

Publications (2)

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JP2023528220A true JP2023528220A (ja) 2023-07-04
JP2023528220A5 JP2023528220A5 (https=) 2024-05-20

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JP2022569147A Pending JP2023528220A (ja) 2020-05-15 2021-05-14 がんを含む加齢関連疾患の治療法として使用するためのミトコンドリア由来ペプチドおよびそのアナログ

Country Status (8)

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US (1) US12577281B2 (https=)
EP (1) EP4149511B1 (https=)
JP (1) JP2023528220A (https=)
KR (1) KR20230019112A (https=)
CN (1) CN115697373A (https=)
CA (1) CA3181427A1 (https=)
MX (1) MX2022014123A (https=)
WO (1) WO2021231988A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115697373A (zh) 2020-05-15 2023-02-03 南加利福尼亚大学 线粒体衍生肽和其类似物作为包括癌症的年龄相关性疾病的治疗的用途
WO2026021591A1 (zh) * 2024-07-26 2026-01-29 南京安吉生物科技有限公司 一种新型调节能量代谢的微肽mp29及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016514681A (ja) * 2013-03-15 2016-05-23 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 代謝と細胞生存を調節するミトコンドリア由来のペプチドｍｏｔｓ３

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9419553D0 (en) * 1994-09-27 1994-11-16 Univ Bristol Polypeptides and their use in the treatment of auto-immune disease
JP2004520803A (ja) 2000-04-21 2004-07-15 コリクサ コーポレイション 尋常性挫瘡の治療および診断のための組成物および方法
CN101586112B (zh) * 2009-06-19 2011-06-22 中国科学院上海有机化学研究所 诺丝七肽的生物合成基因簇
EP3022222A4 (en) * 2013-07-18 2017-06-07 Eutropics Pharmaceuticals, Inc. Differential bh3 mitochondrial profiling
BR112016027911A2 (pt) * 2014-05-28 2017-10-24 Evogene Ltd polinucleotídeos isolados, polipeptídeos e métodos de uso dos mesmos para aumento da tolerância ao estresse abiótico, biomassa e produção da planta
CA3026458A1 (en) * 2016-06-24 2017-12-28 University Of Southern California Mentsh analogs as therapeutics for diabetes, obesity, and their associated diseases and complications
US11208443B2 (en) * 2017-02-14 2021-12-28 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. NAF-1 derived peptides and uses thereof
CN115697373A (zh) 2020-05-15 2023-02-03 南加利福尼亚大学 线粒体衍生肽和其类似物作为包括癌症的年龄相关性疾病的治疗的用途

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016514681A (ja) * 2013-03-15 2016-05-23 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 代謝と細胞生存を調節するミトコンドリア由来のペプチドｍｏｔｓ３

Also Published As

Publication number Publication date
WO2021231988A3 (en) 2022-02-24
WO2021231988A2 (en) 2021-11-18
KR20230019112A (ko) 2023-02-07
CN115697373A (zh) 2023-02-03
CA3181427A1 (en) 2021-11-18
US12577281B2 (en) 2026-03-17
EP4149511B1 (en) 2026-03-25
MX2022014123A (es) 2022-12-08
US20230167161A1 (en) 2023-06-01
EP4149511A2 (en) 2023-03-22
EP4149511A4 (en) 2024-05-22

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