JP2023527531A5 - - Google Patents
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- Publication number
- JP2023527531A5 JP2023527531A5 JP2022573182A JP2022573182A JP2023527531A5 JP 2023527531 A5 JP2023527531 A5 JP 2023527531A5 JP 2022573182 A JP2022573182 A JP 2022573182A JP 2022573182 A JP2022573182 A JP 2022573182A JP 2023527531 A5 JP2023527531 A5 JP 2023527531A5
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- JP
- Japan
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- concentration
- antigen
- antibody
- binding fragment
- medium according
- Prior art date
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010476302.1 | 2020-05-29 | ||
| CN202010476302 | 2020-05-29 | ||
| PCT/CN2021/096585 WO2021239083A1 (zh) | 2020-05-29 | 2021-05-28 | 肿瘤浸润淋巴细胞的种子细胞培养基及其应用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023527531A JP2023527531A (ja) | 2023-06-29 |
| JP2023527531A5 true JP2023527531A5 (enExample) | 2024-05-29 |
| JP7785699B2 JP7785699B2 (ja) | 2025-12-15 |
Family
ID=78745647
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022573182A Active JP7785699B2 (ja) | 2020-05-29 | 2021-05-28 | 腫瘍浸潤リンパ球の種細胞培地及びその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230226111A1 (enExample) |
| EP (1) | EP4159843A4 (enExample) |
| JP (1) | JP7785699B2 (enExample) |
| KR (1) | KR20230019460A (enExample) |
| CN (1) | CN115698267A (enExample) |
| WO (1) | WO2021239083A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20240156910A1 (en) * | 2021-03-16 | 2024-05-16 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Til enhancement via ex vivo stimulation with cd40 agonists |
| CN120769904A (zh) * | 2023-02-27 | 2025-10-10 | 上海君赛生物科技有限公司 | 表达膜结合细胞因子的肿瘤浸润淋巴细胞 |
| CN117025530B (zh) * | 2023-10-10 | 2023-12-12 | 再少年(北京)生物科技有限公司 | 用肿瘤坏死因子受体超家族激动剂扩增肿瘤浸润淋巴细胞（til）的方法 |
| CN121227626A (zh) * | 2024-06-26 | 2025-12-30 | 广州百吉生物制药有限公司 | 一种肿瘤浸润淋巴细胞体外扩增方法 |
| CN119410579B (zh) * | 2024-12-02 | 2026-03-17 | 中国医学科学院输血研究所 | 一种培养nk细胞的方法及应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103374548A (zh) * | 2012-04-27 | 2013-10-30 | 上海诺昊亚医学诊断技术有限公司 | 一种肿瘤浸润淋巴细胞的高效扩增培养液 |
| US11071754B2 (en) * | 2013-03-11 | 2021-07-27 | Case Western Reserve University | Method of generating tumor-specific T cells |
| US20170044496A1 (en) * | 2014-04-10 | 2017-02-16 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Enhanced Expansion of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy |
| CN105713878A (zh) | 2015-12-21 | 2016-06-29 | 杭州特马赛生物技术有限公司 | 一种体外扩增cd8+t细胞的方法 |
| US12048717B2 (en) * | 2016-06-03 | 2024-07-30 | University of Pittsburgh—of the Commonwealth System of Higher Education | Use of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1α) agonists to improve ex vivo expansion of tumor infiltrating lymphocytes (TILS) |
| CN105969731B (zh) * | 2016-07-29 | 2019-10-22 | 青岛市中心医院 | 一种利用恶性胸腹水大量制备高杀伤活性til细胞的方法 |
| KR102576042B1 (ko) | 2016-10-11 | 2023-09-07 | 아게누스 인코포레이티드 | 항-lag-3 항체 및 이의 사용 방법 |
| PL3532607T3 (pl) | 2016-10-26 | 2024-07-01 | Iovance Biotherapeutics, Inc. | Restymulacja kriokonserwowanych limfocytów naciekających guza nowotworowego |
| CN106754703B (zh) * | 2016-12-26 | 2018-03-16 | 浙江丹晖生物科技有限公司 | 一种til细胞体外扩增培养基组合和培养方法 |
| KR102903340B1 (ko) * | 2017-01-06 | 2025-12-26 | 이오반스 바이오테라퓨틱스, 인크. | 종양 괴사 인자 수용체 슈퍼패밀리 (tnfrsf) 효능제를 사용한 종양 침윤 림프구 (til)의 확장 및 til과 tnfrsf 효능제의 치료 조합물 |
| JOP20190224A1 (ar) * | 2017-03-29 | 2019-09-26 | Iovance Biotherapeutics Inc | عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي |
| AU2018243571B2 (en) * | 2017-03-31 | 2024-03-07 | The Board Of Trustees Of The Leland Standford Junior University | Methods of treating T cell exhaustion by inhibiting or modulating T cell receptor signaling |
| WO2019086711A1 (en) * | 2017-11-06 | 2019-05-09 | Ludwig Institute For Cancer Research Ltd | Method for expansion of lymphocytes |
| JP7447011B2 (ja) | 2018-03-28 | 2024-03-11 | ボード オブ リージェンツ ザ ユニヴァーシティ オブ テキサス システム | エフェクターｔ細胞をリプログラムするためのヒストン修飾因子の使用 |
| CN109609451B (zh) * | 2019-01-24 | 2023-02-03 | 清华大学 | 体外快速扩增肾癌的肿瘤浸润淋巴细胞的方法 |
| CN110938594A (zh) * | 2019-09-12 | 2020-03-31 | 夏建川 | 一种功能增强型til细胞的培养方法 |
-
2021
- 2021-05-28 WO PCT/CN2021/096585 patent/WO2021239083A1/zh not_active Ceased
- 2021-05-28 CN CN202180038540.7A patent/CN115698267A/zh active Pending
- 2021-05-28 KR KR1020227046117A patent/KR20230019460A/ko active Pending
- 2021-05-28 EP EP21811798.4A patent/EP4159843A4/en active Pending
- 2021-05-28 JP JP2022573182A patent/JP7785699B2/ja active Active
- 2021-05-28 US US18/000,122 patent/US20230226111A1/en active Pending
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