JP2023527311A5 - - Google Patents
Info
- Publication number
- JP2023527311A5 JP2023527311A5 JP2022571187A JP2022571187A JP2023527311A5 JP 2023527311 A5 JP2023527311 A5 JP 2023527311A5 JP 2022571187 A JP2022571187 A JP 2022571187A JP 2022571187 A JP2022571187 A JP 2022571187A JP 2023527311 A5 JP2023527311 A5 JP 2023527311A5
- Authority
- JP
- Japan
- Prior art keywords
- bispecific
- individualized
- cell
- binding chain
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063027629P | 2020-05-20 | 2020-05-20 | |
| US63/027,629 | 2020-05-20 | ||
| US202063121079P | 2020-12-03 | 2020-12-03 | |
| US63/121,079 | 2020-12-03 | ||
| PCT/IB2021/000340 WO2021234453A1 (en) | 2020-05-20 | 2021-05-19 | Bispecific personalized aptamers |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023527311A JP2023527311A (ja) | 2023-06-28 |
| JP2023527311A5 true JP2023527311A5 (https=) | 2024-05-28 |
| JP7753256B2 JP7753256B2 (ja) | 2025-10-14 |
Family
ID=76845262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022571187A Active JP7753256B2 (ja) | 2020-05-20 | 2021-05-19 | 二重特異性個別化アプタマー |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230193285A1 (https=) |
| EP (1) | EP4153750A1 (https=) |
| JP (1) | JP7753256B2 (https=) |
| CN (1) | CN116419763A (https=) |
| IL (1) | IL298347A (https=) |
| WO (1) | WO2021234453A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7837345B2 (ja) | 2020-12-03 | 2026-03-30 | アーミューン リミテッド | Tリンパ球結合アプタマー |
| US20250215380A1 (en) * | 2023-12-31 | 2025-07-03 | Trenchant BioSystems, Inc. | Optimized geometric design of a cell processing cassette |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10100316B2 (en) * | 2002-11-21 | 2018-10-16 | Archemix Llc | Aptamers comprising CPG motifs |
| JP2007525177A (ja) | 2003-04-21 | 2007-09-06 | アーケミックス コーポレイション | 血小板由来増殖因子に対する安定化アプタマーおよび腫瘍治療剤としてのそれらの使用 |
| WO2010060030A1 (en) * | 2008-11-24 | 2010-05-27 | Arizona Board Of Regents, A Body Corporate Of The State Of Arizona | Tlr ligand-nucleic acid nanostructure as a novel immune modulatory agent and method of using the same |
| WO2010144295A1 (en) * | 2009-06-09 | 2010-12-16 | University Of Miami | Aptamer-targeted costimulatory ligand aptamer |
| US11219635B2 (en) * | 2016-02-19 | 2022-01-11 | City Of Hope | Bi-specific aptamer |
| WO2018144854A1 (en) * | 2017-02-02 | 2018-08-09 | Caris Science, Inc. | Targeted oligonucleotides |
| CN107483987B (zh) | 2017-06-30 | 2020-02-07 | 武汉斗鱼网络科技有限公司 | 一种视频流地址的鉴权方法及装置 |
| WO2020065404A2 (en) * | 2018-09-28 | 2020-04-02 | Augmanity Nano Ltd | Methods and compositions for selection of functional aptamers |
-
2021
- 2021-05-19 CN CN202180060284.1A patent/CN116419763A/zh active Pending
- 2021-05-19 IL IL298347A patent/IL298347A/en unknown
- 2021-05-19 WO PCT/IB2021/000340 patent/WO2021234453A1/en not_active Ceased
- 2021-05-19 JP JP2022571187A patent/JP7753256B2/ja active Active
- 2021-05-19 EP EP21739769.4A patent/EP4153750A1/en active Pending
- 2021-05-19 US US17/926,067 patent/US20230193285A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2022204601B2 (en) | Methods for enhancing efficacy of therapeutic immune cells | |
| US10662427B2 (en) | Compositions and methods for inhibiting gene expression of LPA | |
| RU2744194C2 (ru) | Иммунотерапия рака | |
| EP2491123B1 (en) | Single molecule nucleic acid nanoparticles | |
| CN110914431B (zh) | 经人工操纵的免疫细胞 | |
| JP4843177B2 (ja) | 遺伝子の阻害剤またはサプレッサーおよびその遺伝子の発現産物に結合する分子を含有する混合物 | |
| CN113164507A (zh) | 由多个寡核苷酸构成的通过与靶标的互补相互作用调控基因表达的多靶向核酸构建体 | |
| JP2023527311A5 (https=) | ||
| JP2024512608A5 (https=) | ||
| EP4362984A1 (en) | Compositions and methods for treating cancers | |
| JP7043114B2 (ja) | 細胞を活性化させるための方法およびキット | |
| JP7753256B2 (ja) | 二重特異性個別化アプタマー | |
| AU2022340804A1 (en) | Compositions and methods for treating cancers | |
| IL299855A (en) | Inhibitors of line1 and uses thereof | |
| EP3974531A1 (en) | Asymmetric sirna inhibiting expression of pd-1 | |
| JP2023553193A5 (https=) | ||
| US11053503B2 (en) | Methods and means of generating IL-17 associated antitumor effector cells by inhibition of NR2F6 inhibition | |
| JP7837345B2 (ja) | Tリンパ球結合アプタマー | |
| Chen et al. | Synthetic immunity to break down the bottleneck of cancer immunotherapy | |
| US20230285558A1 (en) | Engineered t cells and tumor-infiltrating lymphocytes to increase tumor killing | |
| WO2025079599A1 (ja) | サブセットレベルで細胞を標的化可能な担体およびその製造方法 | |
| WO2026076302A1 (en) | Novel method to generate "metabolically-fit" til for cancer immunotherapy | |
| CN118159299A (zh) | 用于治疗癌症的组合物和方法 | |
| CN117280033A (zh) | T-淋巴细胞结合适体 | |
| HK40027138A (en) | Artificially manipulated immune cell |