CN116419763A - 双特异性个性化适体 - Google Patents

双特异性个性化适体 Download PDF

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Publication number
CN116419763A
CN116419763A CN202180060284.1A CN202180060284A CN116419763A CN 116419763 A CN116419763 A CN 116419763A CN 202180060284 A CN202180060284 A CN 202180060284A CN 116419763 A CN116419763 A CN 116419763A
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China
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aptamer
bispecific
cancer
personalised
cell
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CN202180060284.1A
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Chinese (zh)
Inventor
G·尼夫
I·卡米-利维
Y·阿米尔
E·拉维
N·斯卡尔卡
N·齐洛尼-哈宁
Z·波德
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Aomiao Co ltd
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Aomiao Co ltd
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Publication of CN116419763A publication Critical patent/CN116419763A/zh
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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CN202180060284.1A 2020-05-20 2021-05-19 双特异性个性化适体 Pending CN116419763A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063027629P 2020-05-20 2020-05-20
US63/027,629 2020-05-20
US202063121079P 2020-12-03 2020-12-03
US63/121,079 2020-12-03
PCT/IB2021/000340 WO2021234453A1 (en) 2020-05-20 2021-05-19 Bispecific personalized aptamers

Publications (1)

Publication Number Publication Date
CN116419763A true CN116419763A (zh) 2023-07-11

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CN202180060284.1A Pending CN116419763A (zh) 2020-05-20 2021-05-19 双特异性个性化适体

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US (1) US20230193285A1 (https=)
EP (1) EP4153750A1 (https=)
JP (1) JP7753256B2 (https=)
CN (1) CN116419763A (https=)
IL (1) IL298347A (https=)
WO (1) WO2021234453A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7837345B2 (ja) 2020-12-03 2026-03-30 アーミューン リミテッド Ｔリンパ球結合アプタマー
US20250215380A1 (en) * 2023-12-31 2025-07-03 Trenchant BioSystems, Inc. Optimized geometric design of a cell processing cassette

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10100316B2 (en) * 2002-11-21 2018-10-16 Archemix Llc Aptamers comprising CPG motifs
JP2007525177A (ja) 2003-04-21 2007-09-06 アーケミックス コーポレイション 血小板由来増殖因子に対する安定化アプタマーおよび腫瘍治療剤としてのそれらの使用
WO2010060030A1 (en) * 2008-11-24 2010-05-27 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Tlr ligand-nucleic acid nanostructure as a novel immune modulatory agent and method of using the same
WO2010144295A1 (en) * 2009-06-09 2010-12-16 University Of Miami Aptamer-targeted costimulatory ligand aptamer
US11219635B2 (en) * 2016-02-19 2022-01-11 City Of Hope Bi-specific aptamer
WO2018144854A1 (en) * 2017-02-02 2018-08-09 Caris Science, Inc. Targeted oligonucleotides
CN107483987B (zh) 2017-06-30 2020-02-07 武汉斗鱼网络科技有限公司 一种视频流地址的鉴权方法及装置
WO2020065404A2 (en) * 2018-09-28 2020-04-02 Augmanity Nano Ltd Methods and compositions for selection of functional aptamers

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Publication number Publication date
JP2023527311A (ja) 2023-06-28
EP4153750A1 (en) 2023-03-29
WO2021234453A1 (en) 2021-11-25
US20230193285A1 (en) 2023-06-22
JP7753256B2 (ja) 2025-10-14
IL298347A (en) 2023-01-01

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