JP2023521036A5 - - Google Patents
Info
- Publication number
- JP2023521036A5 JP2023521036A5 JP2022560245A JP2022560245A JP2023521036A5 JP 2023521036 A5 JP2023521036 A5 JP 2023521036A5 JP 2022560245 A JP2022560245 A JP 2022560245A JP 2022560245 A JP2022560245 A JP 2022560245A JP 2023521036 A5 JP2023521036 A5 JP 2023521036A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pharmaceutically acceptable
- acceptable salt
- salt form
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025102055A JP2025120501A (ja) | 2020-04-03 | 2025-06-18 | がんの治療で使用するためのミルダメチニブ及びリフィラフェニブの同時投与 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063005153P | 2020-04-03 | 2020-04-03 | |
| US63/005,153 | 2020-04-03 | ||
| PCT/US2021/025551 WO2021202981A1 (en) | 2020-04-03 | 2021-04-02 | Co-administration of mirdametinib and lifirafenib for use in treating cancers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025102055A Division JP2025120501A (ja) | 2020-04-03 | 2025-06-18 | がんの治療で使用するためのミルダメチニブ及びリフィラフェニブの同時投与 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023521036A JP2023521036A (ja) | 2023-05-23 |
| JP2023521036A5 true JP2023521036A5 (enExample) | 2024-04-11 |
| JP7748386B2 JP7748386B2 (ja) | 2025-10-02 |
Family
ID=75674969
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022560245A Active JP7748386B2 (ja) | 2020-04-03 | 2021-04-02 | がんの治療で使用するためのミルダメチニブ及びリフィラフェニブの同時投与 |
| JP2025102055A Pending JP2025120501A (ja) | 2020-04-03 | 2025-06-18 | がんの治療で使用するためのミルダメチニブ及びリフィラフェニブの同時投与 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025102055A Pending JP2025120501A (ja) | 2020-04-03 | 2025-06-18 | がんの治療で使用するためのミルダメチニブ及びリフィラフェニブの同時投与 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US12667560B2 (enExample) |
| EP (1) | EP4125842B1 (enExample) |
| JP (2) | JP7748386B2 (enExample) |
| KR (1) | KR20230048476A (enExample) |
| CN (1) | CN116194095B (enExample) |
| AU (1) | AU2021246141A1 (enExample) |
| BR (1) | BR112022019914A2 (enExample) |
| CA (1) | CA3174223A1 (enExample) |
| CL (1) | CL2022002682A1 (enExample) |
| CO (1) | CO2022015891A2 (enExample) |
| DK (1) | DK4125842T3 (enExample) |
| ES (1) | ES2985012T3 (enExample) |
| FI (1) | FI4125842T3 (enExample) |
| HU (1) | HUE067894T2 (enExample) |
| IL (1) | IL296878A (enExample) |
| MX (1) | MX2022012351A (enExample) |
| PE (1) | PE20231211A1 (enExample) |
| PL (1) | PL4125842T3 (enExample) |
| PT (1) | PT4125842T (enExample) |
| TW (1) | TWI893097B (enExample) |
| WO (1) | WO2021202981A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL4125842T3 (pl) | 2020-04-03 | 2024-10-14 | Beigene, Ltd. | Równoczesne podawanie mirdametynibu i lifirafenibu do stosowania w leczeniu nowotworów |
| US20230293464A1 (en) * | 2022-03-17 | 2023-09-21 | SpringWorks Therapeutics Inc. | Treatment of pancreatic ductal adenocarcinoma with mirdametinib |
| MX2024011403A (es) * | 2022-03-17 | 2024-09-23 | Springworks Therapeutics Inc | Tratamiento con mirdametinib. |
| WO2023209611A1 (en) * | 2022-04-26 | 2023-11-02 | Beigene Switzerland Gmbh | Methods of treating cancer with a b-raf inhibitor, in particular lifirafenib |
| EP4601631A4 (en) * | 2022-10-14 | 2026-04-08 | Springworks Therapeutics Inc | COMBINATION INTENDED FOR USE IN CANCER TREATMENT |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004501190A (ja) | 2000-06-23 | 2004-01-15 | テバ ファーマシューティカル インダストリーズ リミティド | 治療薬の胃部保留および制御された放出のための急速膨張する組成物とその組成物を含む剤形 |
| AU7349801A (en) | 2000-07-19 | 2002-01-30 | Warner Lambert Co | Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids |
| EP1562601A1 (en) | 2002-11-15 | 2005-08-17 | Warner-Lambert Company LLC | Combination chemotherapy comprising a mek inhibitor and capecitabine for treating cancer |
| KR101013932B1 (ko) | 2003-10-21 | 2011-02-14 | 워너-램버트 캄파니 엘엘씨 | Ｎ-[(ｒ)-2,3-디히드록시-프로폭시]-3,4-디플루오로-2-(2-플루오로-4-요오도페닐아미노)-벤자미드 다형체 형태 |
| WO2006061712A2 (en) | 2004-12-10 | 2006-06-15 | Pfizer Inc. | Use of mek inhibitors in treating abnormal cell growth |
| WO2006134469A1 (en) | 2005-06-14 | 2006-12-21 | Warner-Lambert Company Llc | Methods of preparing mek inhibitor |
| WO2007042885A2 (en) | 2005-10-07 | 2007-04-19 | Pfizer Products Inc. | Therapeutic combination comprising methotrexate and a specified inhibitor of mek1 and mek2 |
| TR201815685T4 (tr) | 2011-04-01 | 2018-11-21 | Genentech Inc | Kanser tedavisi için akt ve mek inhibe edici bileşiklerin kombinasyonları. |
| GB201320729D0 (en) | 2013-11-25 | 2014-01-08 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
| AU2016248376B2 (en) | 2015-04-15 | 2020-10-08 | Beone Medicines I Gmbh | Maleate salts of a B-RAF kinase inhibitor, crystalline forms, methods of preparation, and uses therefore |
| KR102811888B1 (ko) | 2017-09-08 | 2025-05-27 | 에프. 호프만-라 로슈 아게 | 암의 진단 및 치료 방법 |
| WO2019113345A1 (en) | 2017-12-06 | 2019-06-13 | Spyro Mousses | Combination of cancer therapeutics for treatment of cancer and hyperproliferative diseases |
| EP3560516A1 (en) | 2018-04-27 | 2019-10-30 | Bergen Teknologioverforing AS | Combination therapy including beta-sitosterol in combination with at least one of a braf inhibitor, a mek inhibitor or an erk inhibitor and methods and use thereof |
| US12208099B2 (en) | 2018-09-10 | 2025-01-28 | Mirati Therapeutics, Inc. | Combination therapies |
| PL4125842T3 (pl) | 2020-04-03 | 2024-10-14 | Beigene, Ltd. | Równoczesne podawanie mirdametynibu i lifirafenibu do stosowania w leczeniu nowotworów |
| US11066358B1 (en) | 2021-02-17 | 2021-07-20 | Warner-Lambert Company Llc | Compositions of essentially pure form IV of N-((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide and uses thereof |
| US11571402B2 (en) | 2021-02-17 | 2023-02-07 | Springworks Therapeutics, Inc. | Dispersible formulations of N-((R)-2,3-dihydroxypropoly)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide and uses thereof |
| US11084780B1 (en) | 2021-02-17 | 2021-08-10 | Springworks Therapeutics, Inc. | Crystalline solids of MEK inhibitor N-((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide and uses thereof |
| MX2024011403A (es) | 2022-03-17 | 2024-09-23 | Springworks Therapeutics Inc | Tratamiento con mirdametinib. |
| PE20242177A1 (es) | 2022-03-17 | 2024-11-07 | St Jude Childrens Res Hospital Inc | Tratamiento del glioma de bajo grado con mirdametinib |
-
2021
- 2021-04-02 PL PL21721706.6T patent/PL4125842T3/pl unknown
- 2021-04-02 ES ES21721706T patent/ES2985012T3/es active Active
- 2021-04-02 TW TW110112271A patent/TWI893097B/zh active
- 2021-04-02 CA CA3174223A patent/CA3174223A1/en active Pending
- 2021-04-02 FI FIEP21721706.6T patent/FI4125842T3/fi active
- 2021-04-02 JP JP2022560245A patent/JP7748386B2/ja active Active
- 2021-04-02 PT PT217217066T patent/PT4125842T/pt unknown
- 2021-04-02 DK DK21721706.6T patent/DK4125842T3/da active
- 2021-04-02 HU HUE21721706A patent/HUE067894T2/hu unknown
- 2021-04-02 PE PE2022002181A patent/PE20231211A1/es unknown
- 2021-04-02 AU AU2021246141A patent/AU2021246141A1/en active Pending
- 2021-04-02 KR KR1020227038490A patent/KR20230048476A/ko active Pending
- 2021-04-02 IL IL296878A patent/IL296878A/en unknown
- 2021-04-02 WO PCT/US2021/025551 patent/WO2021202981A1/en not_active Ceased
- 2021-04-02 US US17/995,002 patent/US12667560B2/en active Active
- 2021-04-02 EP EP21721706.6A patent/EP4125842B1/en active Active
- 2021-04-02 BR BR112022019914A patent/BR112022019914A2/pt unknown
- 2021-04-02 CN CN202180036587.XA patent/CN116194095B/zh active Active
- 2021-04-02 MX MX2022012351A patent/MX2022012351A/es unknown
-
2022
- 2022-09-30 CL CL2022002682A patent/CL2022002682A1/es unknown
- 2022-11-03 CO CONC2022/0015891A patent/CO2022015891A2/es unknown
-
2025
- 2025-06-18 JP JP2025102055A patent/JP2025120501A/ja active Pending
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