JP2023519261A5 - - Google Patents

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Publication number
JP2023519261A5
JP2023519261A5 JP2022557789A JP2022557789A JP2023519261A5 JP 2023519261 A5 JP2023519261 A5 JP 2023519261A5 JP 2022557789 A JP2022557789 A JP 2022557789A JP 2022557789 A JP2022557789 A JP 2022557789A JP 2023519261 A5 JP2023519261 A5 JP 2023519261A5
Authority
JP
Japan
Prior art keywords
groups
antibody
cancer
pharmaceutically acceptable
drug conjugate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022557789A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023519261A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2021/082857 external-priority patent/WO2021190583A1/zh
Publication of JP2023519261A publication Critical patent/JP2023519261A/ja
Publication of JP2023519261A5 publication Critical patent/JP2023519261A5/ja
Pending legal-status Critical Current

Links

JP2022557789A 2020-03-25 2021-03-25 抗psma抗体-エキサテカン類似体複合体及びその医薬用途 Pending JP2023519261A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202010218297 2020-03-25
CN202010218297.4 2020-03-25
PCT/CN2021/082857 WO2021190583A1 (zh) 2020-03-25 2021-03-25 抗psma抗体-依喜替康类似物偶联物及其医药用途

Publications (2)

Publication Number Publication Date
JP2023519261A JP2023519261A (ja) 2023-05-10
JP2023519261A5 true JP2023519261A5 (OSRAM) 2024-04-02

Family

ID=77890968

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022557789A Pending JP2023519261A (ja) 2020-03-25 2021-03-25 抗psma抗体-エキサテカン類似体複合体及びその医薬用途

Country Status (12)

Country Link
US (1) US20230140397A1 (OSRAM)
EP (1) EP4130006A4 (OSRAM)
JP (1) JP2023519261A (OSRAM)
KR (1) KR20220160016A (OSRAM)
CN (1) CN115298186B (OSRAM)
AU (1) AU2021240756A1 (OSRAM)
BR (1) BR112022019027A2 (OSRAM)
CA (1) CA3177279A1 (OSRAM)
MX (1) MX2022011808A (OSRAM)
TW (1) TWI888517B (OSRAM)
WO (1) WO2021190583A1 (OSRAM)
ZA (1) ZA202210724B (OSRAM)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3237844A1 (en) 2021-11-15 2023-05-19 Systimmune, Inc. Bispecific antibody-camptothecin drug conjugate and pharmaceutical use thereof
US11814394B2 (en) * 2021-11-16 2023-11-14 Genequantum Healthcare (Suzhou) Co., Ltd. Exatecan derivatives, linker-payloads, and conjugates and thereof
WO2024012566A2 (en) 2022-07-15 2024-01-18 Genequantum Healthcare (Suzhou) Co., Ltd. Antibody, linkers, payload, conjugates and applications thereof
KR20260040624A (ko) * 2023-07-25 2026-03-25 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 c-Met를 표적으로 하는 항체-약물 접합체 및 이의 의학적 용도
CN121568723A (zh) * 2023-08-04 2026-02-24 江苏恒瑞医药股份有限公司 抗psma抗体-药物偶联物及其医药用途
TW202542201A (zh) * 2023-12-29 2025-11-01 瑞士商T O A D 腫瘤學股份有限公司 抗psma軛合物及其使用方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208020A (en) 1989-10-25 1993-05-04 Immunogen Inc. Cytotoxic agents comprising maytansinoids and their therapeutic use
US6504029B1 (en) 1995-04-10 2003-01-07 Daiichi Pharmaceutical Co., Ltd. Condensed-hexacyclic compounds and a process therefor
WO2003000657A1 (en) 2001-06-20 2003-01-03 Daiichi Pharmaceutical Co., Ltd. Diamine derivatives
EP2360169B1 (en) * 2001-10-23 2015-10-14 Psma Development Company, L.L.C. PSMA antibodies
EP3434275A1 (en) 2003-11-06 2019-01-30 Seattle Genetics, Inc. Assay for cancer cells based on the use of auristatin conjugates with antibodies
CN103127523A (zh) * 2005-06-20 2013-06-05 Psma开发有限公司 Psma抗体-药物缀合物
EP2794576A1 (en) 2011-12-21 2014-10-29 Ardelyx, Inc. Non-systemic tgr5 agonists
CA2861071C (en) 2012-01-13 2017-09-12 The General Hospital Corporation Etomidate and metomidate derivatives and their use as anesthetics
WO2014057687A1 (ja) 2012-10-11 2014-04-17 第一三共株式会社 抗体-薬物コンジュゲート
US9107960B2 (en) * 2012-12-13 2015-08-18 Immunimedics, Inc. Antibody-SN-38 immunoconjugates with a CL2A linker
HRP20190431T1 (hr) 2014-01-31 2019-04-19 Daiichi Sankyo Company, Limited Anti-her2 antitijelo-lijek konjugat
ES2754348T3 (es) * 2014-04-10 2020-04-17 Daiichi Sankyo Co Ltd Conjugado de (anticuerpo anti-HER2)-fármaco
SI3204018T1 (sl) * 2014-10-07 2021-11-30 Immunomedics, Inc. Neoadjuvantna uporaba konjugatov protitelo-zdravilo
US10195175B2 (en) * 2015-06-25 2019-02-05 Immunomedics, Inc. Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors
US20190022092A1 (en) * 2015-09-15 2019-01-24 Acerta Pharma B.V. Therapeutic Combinations of a BTK Inhibitor and a GITR Binding Molecule, a 4-1BB Agonist, or an OX40 Agonist
US11485792B2 (en) * 2016-06-06 2022-11-01 Polytherics Limited Antibodies, uses thereof and conjugates thereof
CA3103936A1 (en) * 2018-06-18 2019-12-26 Eureka Therapeutics, Inc. Constructs targeting prostate-specific membrane antigen (psma) and uses thereof
BR112021004656A2 (pt) * 2018-09-26 2021-06-01 Jiangsu Hengrui Medicine Co., Ltd. conjugado fármaco-ligante de análogo exatecano, método para preparar o mesmo e aplicação do mesmo
AU2020347715A1 (en) * 2019-09-18 2022-04-07 Systimmune, Inc. Camptothecin derivative and conjugate thereof

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