JP2023515974A5 - - Google Patents

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Publication number
JP2023515974A5
JP2023515974A5 JP2022551593A JP2022551593A JP2023515974A5 JP 2023515974 A5 JP2023515974 A5 JP 2023515974A5 JP 2022551593 A JP2022551593 A JP 2022551593A JP 2022551593 A JP2022551593 A JP 2022551593A JP 2023515974 A5 JP2023515974 A5 JP 2023515974A5
Authority
JP
Japan
Prior art keywords
seq
modified
nucleic acid
modified oligonucleotide
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022551593A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023515974A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/019960 external-priority patent/WO2021174036A1/en
Publication of JP2023515974A publication Critical patent/JP2023515974A/ja
Publication of JP2023515974A5 publication Critical patent/JP2023515974A5/ja
Pending legal-status Critical Current

Links

JP2022551593A 2020-02-28 2021-02-26 Scn1a発現を調節するための化合物及び方法 Pending JP2023515974A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062983555P 2020-02-28 2020-02-28
US62/983,555 2020-02-28
US202063085111P 2020-09-29 2020-09-29
US63/085,111 2020-09-29
PCT/US2021/019960 WO2021174036A1 (en) 2020-02-28 2021-02-26 Compounds and methods for modulating scn1a expression

Publications (2)

Publication Number Publication Date
JP2023515974A JP2023515974A (ja) 2023-04-17
JP2023515974A5 true JP2023515974A5 (enExample) 2024-03-05

Family

ID=77491960

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022551593A Pending JP2023515974A (ja) 2020-02-28 2021-02-26 Scn1a発現を調節するための化合物及び方法

Country Status (6)

Country Link
US (1) US20230043648A1 (enExample)
EP (1) EP4110919A4 (enExample)
JP (1) JP2023515974A (enExample)
TW (1) TW202140788A (enExample)
UY (1) UY39104A (enExample)
WO (1) WO2021174036A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019239971B2 (en) * 2018-03-21 2025-09-11 Regeneron Pharmaceuticals, Inc. 17beta-hydroxysteroid dehydrogenase type 13 (HSD17b13) iRNA compositions and methods of use thereof
JP2024534157A (ja) * 2021-08-27 2024-09-18 アイオーニス ファーマシューティカルズ, インコーポレーテッド Scn1a発現を調節するための化合物及び方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102213609B1 (ko) * 2012-07-13 2021-02-08 웨이브 라이프 사이언시스 리미티드 키랄 제어
EP3484524B1 (en) * 2016-07-15 2022-11-09 Ionis Pharmaceuticals, Inc. Compounds and methods for modulation of smn2
KR102318434B1 (ko) * 2017-08-25 2021-11-01 스톡 테라퓨틱스, 인크. 병태 및 질환 치료용 안티센스 올리고머
US10758629B2 (en) * 2018-05-29 2020-09-01 Sarepta Therapeutics, Inc. Exon skipping oligomer conjugates for muscular dystrophy
BR112021003224A2 (pt) * 2018-08-20 2021-07-20 Rogcon, Inc. oligonucleotídeos antissentido direcionados a scn2a para o tratamento de encefalopatias por scn1a
BR112022010882A2 (pt) * 2019-12-06 2022-10-04 Stoke Therapeutics Inc Oligômeros antissenso para tratamento de condições e doenças

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