JP2023514788A - リンパ球集団およびそれを生産するための方法 - Google Patents

リンパ球集団およびそれを生産するための方法 Download PDF

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JP2023514788A
JP2023514788A JP2022551251A JP2022551251A JP2023514788A JP 2023514788 A JP2023514788 A JP 2023514788A JP 2022551251 A JP2022551251 A JP 2022551251A JP 2022551251 A JP2022551251 A JP 2022551251A JP 2023514788 A JP2023514788 A JP 2023514788A
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cells
nkt
dexamethasone
nkt cells
cell
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JP2023514788A5 (enExample
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テレサ デイシャー、
スコット ウェイン マッケイ、
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エーブイエム・バイオテクノロジー・エルエルシー
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/22—Immunosuppressive or immunotolerising
    • A—HUMAN NECESSITIES
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    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/416—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
    • A—HUMAN NECESSITIES
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  • Cell Biology (AREA)
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JP2022551251A 2020-02-28 2021-02-26 リンパ球集団およびそれを生産するための方法 Pending JP2023514788A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202062983005P 2020-02-28 2020-02-28
US62/983,005 2020-02-28
US202063009050P 2020-04-13 2020-04-13
US63/009,050 2020-04-13
US202063123054P 2020-12-09 2020-12-09
US63/123,054 2020-12-09
PCT/US2021/019773 WO2021173900A1 (en) 2020-02-28 2021-02-26 Lypmphocyte population and methods for producing same

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JP2023514788A true JP2023514788A (ja) 2023-04-10
JP2023514788A5 JP2023514788A5 (enExample) 2024-03-01

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EP (1) EP4110902A1 (enExample)
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KR (1) KR20220148859A (enExample)
CN (1) CN115516085A (enExample)
AU (1) AU2021227925A1 (enExample)
BR (1) BR112022016803A2 (enExample)
CA (1) CA3168378A1 (enExample)
IL (1) IL295952A (enExample)
MX (1) MX2022010674A (enExample)
WO (1) WO2021173900A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023524434A (ja) * 2020-04-29 2023-06-12 エーブイエム・バイオテクノロジー・エルエルシー 新規療法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4395784A1 (en) * 2021-09-01 2024-07-10 AVM Biotechnology, LLC Lymphocyte population and methods for producing same
CN114561362B (zh) * 2021-12-28 2023-12-15 江西省疾病预防控制中心 一种人源肾综合征出血热汉坦病毒分离方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009076696A1 (en) * 2007-12-19 2009-06-25 Cell Med Research Gmbh Method for determining b, t, nk and nkt cells
EP3488851A1 (en) * 2018-10-03 2019-05-29 AVM Biotechnology, LLC Immunoablative therapies
JP2019515888A (ja) * 2017-04-01 2019-06-13 エーブイエム・バイオテクノロジー・エルエルシー 細胞免疫療法前の細胞毒性プレコンディショニングの代替
WO2020021045A2 (en) * 2018-07-26 2020-01-30 Ospedale Pediatrico Bambino Gesù (Opbg) Therapeutic preparations of gamma-delta t cells and natural killer cells and methods for manufacture and use

Family Cites Families (3)

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WO2012074116A1 (ja) * 2010-12-02 2012-06-07 独立行政法人理化学研究所 アロNKT細胞を用いた免疫療法およびそのためのT細胞抗原受容体（TCR）遺伝子のα鎖領域が均一なVα-Jαに再構成されている細胞および該細胞由来NKT細胞のバンキング
WO2015112793A2 (en) * 2014-01-27 2015-07-30 St. Jude Children's Research Hospital, Inc. Methods of expanding ex vivo natural killer t (nkt) cells and therapeutic uses thereof
CN113286811B (zh) * 2018-07-30 2024-12-06 南加利福尼亚大学 改善过继性细胞疗法的效力和安全性

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009076696A1 (en) * 2007-12-19 2009-06-25 Cell Med Research Gmbh Method for determining b, t, nk and nkt cells
JP2019515888A (ja) * 2017-04-01 2019-06-13 エーブイエム・バイオテクノロジー・エルエルシー 細胞免疫療法前の細胞毒性プレコンディショニングの代替
WO2020021045A2 (en) * 2018-07-26 2020-01-30 Ospedale Pediatrico Bambino Gesù (Opbg) Therapeutic preparations of gamma-delta t cells and natural killer cells and methods for manufacture and use
EP3488851A1 (en) * 2018-10-03 2019-05-29 AVM Biotechnology, LLC Immunoablative therapies

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF IMMUNOLOGICAL METHODS, vol. 475, JPN6025009163, 2019, pages 112287, ISSN: 0005764957 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023524434A (ja) * 2020-04-29 2023-06-12 エーブイエム・バイオテクノロジー・エルエルシー 新規療法

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WO2021173900A1 (en) 2021-09-02
CN115516085A (zh) 2022-12-23
IL295952A (en) 2022-10-01
CA3168378A1 (en) 2021-09-02
MX2022010674A (es) 2022-11-30
AU2021227925A1 (en) 2022-09-15
EP4110902A1 (en) 2023-01-04
KR20220148859A (ko) 2022-11-07
US20230096897A1 (en) 2023-03-30
BR112022016803A2 (pt) 2022-11-08

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