JP2023514732A - アルファ－２－アドレナリン受容体アゴニストの医薬組成物および視力を改善するためのその使用 - Google Patents

アルファ－２－アドレナリン受容体アゴニストの医薬組成物および視力を改善するためのその使用 Download PDF

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JP2023514732A
JP2023514732A JP2022550240A JP2022550240A JP2023514732A JP 2023514732 A JP2023514732 A JP 2023514732A JP 2022550240 A JP2022550240 A JP 2022550240A JP 2022550240 A JP2022550240 A JP 2022550240A JP 2023514732 A JP2023514732 A JP 2023514732A
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use according
pharmaceutical composition
improvement
individual
reduction
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Japanese (ja)
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JP2023514732A5 (enExample
Inventor
リチャード グラハム
ケ ウー
マスード ファヒド
モハメド ディバス
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Allergan Inc
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Allergan Inc
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Publication of JP2023514732A publication Critical patent/JP2023514732A/ja
Publication of JP2023514732A5 publication Critical patent/JP2023514732A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2022550240A 2020-02-20 2021-02-19 アルファ－２－アドレナリン受容体アゴニストの医薬組成物および視力を改善するためのその使用 Pending JP2023514732A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062979214P 2020-02-20 2020-02-20
US62/979,214 2020-02-20
PCT/US2021/018906 WO2021168349A1 (en) 2020-02-20 2021-02-19 Pharmaceutical compositions of alpha-2-adrenergic receptor agonists and their use for improving vision

Publications (2)

Publication Number Publication Date
JP2023514732A true JP2023514732A (ja) 2023-04-07
JP2023514732A5 JP2023514732A5 (enExample) 2024-02-28

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Family Applications (1)

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JP2022550240A Pending JP2023514732A (ja) 2020-02-20 2021-02-19 アルファ－２－アドレナリン受容体アゴニストの医薬組成物および視力を改善するためのその使用

Country Status (12)

Country Link
US (2) US20210260041A1 (enExample)
EP (1) EP4106728A1 (enExample)
JP (1) JP2023514732A (enExample)
KR (1) KR20220157392A (enExample)
CN (1) CN115443125A (enExample)
AU (1) AU2021224232A1 (enExample)
BR (1) BR112022016730A2 (enExample)
CA (1) CA3168767A1 (enExample)
IL (1) IL295782A (enExample)
MX (1) MX2022010317A (enExample)
TW (1) TW202139998A (enExample)
WO (1) WO2021168349A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022182740A1 (en) 2021-02-24 2022-09-01 Ocular Therapeutix, Inc. Intracanalicular depot inserter device

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09507216A (ja) * 1993-12-17 1997-07-22 ザ、プロクター、エンド、ギャンブル、カンパニー ５−（２−イミダゾリニルアミノ）ベンゾイミダゾール誘導体、それらの製法及びα−２−アドレノセプター作動剤としてのそれらの用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495583B1 (en) 1997-03-25 2002-12-17 Synaptic Pharmaceutical Corporation Benzimidazole derivatives
KR102337046B1 (ko) 2010-01-22 2021-12-08 알러간, 인코포레이티드 전방내 서방성 치료제 이식물
WO2014159576A1 (en) * 2013-03-14 2014-10-02 Allergan, Inc. Alpha-2 adrenergic agonist for treating intraocular pressure and ocular diseases through intravitreal and intracameral routes
ES2751681T3 (es) 2013-03-15 2020-04-01 Allergan Inc Implante intraocular que contiene prostamida
EP2978406A1 (en) 2013-03-27 2016-02-03 Forsight Vision5, Inc. Bimatoprost ocular silicone inserts and methods of use thereof
WO2014165308A2 (en) 2013-04-01 2014-10-09 Allergan, Inc. Microsphere drug delivery system for sustained intraocular release
EP3283004A4 (en) 2015-04-13 2018-12-05 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
EP3840750A1 (en) * 2018-08-21 2021-06-30 Allergan, Inc. The use of alpha-2-adrenergic receptor agonists for improving vision

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09507216A (ja) * 1993-12-17 1997-07-22 ザ、プロクター、エンド、ギャンブル、カンパニー ５−（２−イミダゾリニルアミノ）ベンゾイミダゾール誘導体、それらの製法及びα−２−アドレノセプター作動剤としてのそれらの用途

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Publication number Publication date
AU2021224232A1 (en) 2022-10-13
KR20220157392A (ko) 2022-11-29
CA3168767A1 (en) 2021-08-26
TW202139998A (zh) 2021-11-01
US20210260041A1 (en) 2021-08-26
BR112022016730A2 (pt) 2022-11-08
EP4106728A1 (en) 2022-12-28
WO2021168349A1 (en) 2021-08-26
US20240335425A1 (en) 2024-10-10
MX2022010317A (es) 2023-01-24
CN115443125A (zh) 2022-12-06
IL295782A (en) 2022-10-01

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