JP2023514446A5 - - Google Patents

Info

Publication number
JP2023514446A5
JP2023514446A5 JP2022550865A JP2022550865A JP2023514446A5 JP 2023514446 A5 JP2023514446 A5 JP 2023514446A5 JP 2022550865 A JP2022550865 A JP 2022550865A JP 2022550865 A JP2022550865 A JP 2022550865A JP 2023514446 A5 JP2023514446 A5 JP 2023514446A5
Authority
JP
Japan
Prior art keywords
amino acid
aav2
cap
viral vector
vector particle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022550865A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023514446A (ja
JP7737385B2 (ja
Filing date
Publication date
Priority claimed from EP20158633.6A external-priority patent/EP3868875A1/en
Application filed filed Critical
Publication of JP2023514446A publication Critical patent/JP2023514446A/ja
Publication of JP2023514446A5 publication Critical patent/JP2023514446A5/ja
Application granted granted Critical
Publication of JP7737385B2 publication Critical patent/JP7737385B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022550865A 2020-02-20 2021-02-22 遺伝子療法のためのａａｖ２をベースとするウイルスベクター粒子 Active JP7737385B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20158633.6 2020-02-20
EP20158633.6A EP3868875A1 (en) 2020-02-20 2020-02-20 Viral vector particle based on aav2 for gene therapy
PCT/EP2021/054347 WO2021165544A1 (en) 2020-02-20 2021-02-22 Viral vector particle based on aav2 for gene therapy

Publications (3)

Publication Number Publication Date
JP2023514446A JP2023514446A (ja) 2023-04-05
JP2023514446A5 true JP2023514446A5 (cg-RX-API-DMAC7.html) 2024-02-26
JP7737385B2 JP7737385B2 (ja) 2025-09-10

Family

ID=69804442

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022550865A Active JP7737385B2 (ja) 2020-02-20 2021-02-22 遺伝子療法のためのａａｖ２をベースとするウイルスベクター粒子

Country Status (4)

Country Link
US (1) US20230074198A1 (cg-RX-API-DMAC7.html)
EP (2) EP3868875A1 (cg-RX-API-DMAC7.html)
JP (1) JP7737385B2 (cg-RX-API-DMAC7.html)
WO (1) WO2021165544A1 (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240095539A (ko) 2021-10-08 2024-06-25 디노 테라퓨틱스, 인코포레이티드 캡시드 변이체 및 이의 사용 방법
KR20250120301A (ko) 2022-12-14 2025-08-08 아비젠 게엠베하 심장 질환 및 심장 기능 장애 관련 질환 치료를 위해 간 친화성 감소 및 심장 세포 형질도입이 향상된 재조합-아데노 관련 바이러스 유전자 치료 벡터
WO2024191778A1 (en) 2023-03-10 2024-09-19 Dyno Therapeutics, Inc. Capsid polypeptides and methods of use thereof
AU2024332181A1 (en) 2023-08-31 2026-02-12 Dyno Therapeutics, Inc. Capsid polypeptides and methods of use thereof
TW202545971A (zh) 2024-02-08 2025-12-01 美商戴諾治療公司 殼體多肽及其使用方法
WO2026064442A2 (en) 2024-09-18 2026-03-26 Dyno Therapeutics, Inc. Capsid polypeptides and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070172460A1 (en) * 2003-03-19 2007-07-26 Jurgen Kleinschmidt Random peptide library displayed on aav vectors
US12043848B2 (en) * 2017-10-16 2024-07-23 Vigeneron Gmbh AAV vectors

Similar Documents

Publication Publication Date Title
JP2023514446A5 (cg-RX-API-DMAC7.html)
CN113795574A (zh) 具有降低的肝向性和增加的肌肉转导的AAV9和AAVrh74之间的肽修饰的杂合重组腺相关病毒血清型
JP2023544683A5 (cg-RX-API-DMAC7.html)
JP2023529315A (ja) 機能的ａａｖカプシドのハイスループット工学操作
RU2020113681A (ru) Капсиды вариантов аденоассоциированных вирусов и методы их применения
JP7846169B2 (ja) 細胞透過性ペプチド
JP2022523679A (ja) 体液性免疫を回避する組成物および方法
US12428445B2 (en) Mini-nucleosome core proteins and use in nucleic acid delivery
JP2024513949A5 (cg-RX-API-DMAC7.html)
JP2019524090A5 (cg-RX-API-DMAC7.html)
CN116368157A (zh) 用于溶解蛋白质聚集体的组合物和方法
JP2023535121A5 (cg-RX-API-DMAC7.html)
CN114276419B (zh) 肌肉高亲和性的新型腺相关病毒衣壳蛋白及其应用
FI4536686T3 (fi) Lihaksen parannetun transduktiotehokkuuden omaava peptidimodifioitu aav-kapsidi
JP2024537250A5 (cg-RX-API-DMAC7.html)
JP2024503091A5 (cg-RX-API-DMAC7.html)
WO2007010989A1 (ja) 神経分化誘導ペプチド及びその利用
JP2025506173A5 (cg-RX-API-DMAC7.html)
JP2008502323A5 (cg-RX-API-DMAC7.html)
JP2025510975A5 (cg-RX-API-DMAC7.html)
JP2025510946A5 (cg-RX-API-DMAC7.html)
CN108314737A (zh) 一种重组蛋白及其制备方法和应用
WO2023014724A2 (en) Scaffold matrix attachment regions for gene therapy
JP2018522555A5 (cg-RX-API-DMAC7.html)
AU2024243405A1 (en) Super minimal inverted terminal repeat (itr) sequences and uses thereof