JP2023511229A5 - - Google Patents
Info
- Publication number
- JP2023511229A5 JP2023511229A5 JP2022569300A JP2022569300A JP2023511229A5 JP 2023511229 A5 JP2023511229 A5 JP 2023511229A5 JP 2022569300 A JP2022569300 A JP 2022569300A JP 2022569300 A JP2022569300 A JP 2022569300A JP 2023511229 A5 JP2023511229 A5 JP 2023511229A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- methyl
- alkylene
- dihydroxy
- piperazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2000789.4A GB202000789D0 (en) | 2020-01-20 | 2020-01-20 | Novel probe molecules |
| GB2000789.4 | 2020-01-20 | ||
| GBGB2003559.8A GB202003559D0 (en) | 2020-03-11 | 2020-03-11 | Novel probe molecules |
| GB2003559.8 | 2020-03-11 | ||
| PCT/GB2021/050122 WO2021148786A1 (en) | 2020-01-20 | 2021-01-20 | Isoindoline derivatives which bind to an atp binding site |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023511229A JP2023511229A (ja) | 2023-03-16 |
| JP2023511229A5 true JP2023511229A5 (https=) | 2025-04-03 |
| JP7671308B2 JP7671308B2 (ja) | 2025-05-01 |
Family
ID=74285509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022569300A Active JP7671308B2 (ja) | 2020-01-20 | 2021-01-20 | Ａｔｐ結合部位に結合するイソインドリン誘導体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12517130B2 (https=) |
| EP (1) | EP4093731A1 (https=) |
| JP (1) | JP7671308B2 (https=) |
| CN (1) | CN115397811B (https=) |
| AU (1) | AU2021211925A1 (https=) |
| CA (1) | CA3168495A1 (https=) |
| WO (1) | WO2021148786A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2021211925A1 (en) | 2020-01-20 | 2022-08-25 | Neophore Limited | Isoindoline derivatives which bind to an ATP binding site |
| GB202008201D0 (en) | 2020-06-01 | 2020-07-15 | Neophore Ltd | Inhibitor compounds |
| GB202110373D0 (en) * | 2021-07-19 | 2021-09-01 | Neophore Ltd | Inhibitor compounds |
| GB202307924D0 (en) * | 2023-05-26 | 2023-07-12 | Neophore Ltd | Inhibitor compounds |
| CN117586174B (zh) * | 2024-01-19 | 2024-05-10 | 中国药科大学 | 用于诊断结直肠癌的近红外荧光探针及其制法和应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0202133D0 (sv) | 2002-07-08 | 2002-07-08 | Astrazeneca Ab | Novel compounds |
| JP2008540395A (ja) | 2005-05-03 | 2008-11-20 | ファイザー・インク | アミドレソルシノール化合物 |
| GB0620259D0 (en) * | 2006-10-12 | 2006-11-22 | Astex Therapeutics Ltd | Pharmaceutical compounds |
| JP5410285B2 (ja) | 2006-10-12 | 2014-02-05 | アステックス、セラピューティックス、リミテッド | 医薬化合物 |
| JP5518478B2 (ja) | 2006-10-12 | 2014-06-11 | アステックス、セラピューティックス、リミテッド | 医薬化合物 |
| WO2009060835A1 (ja) | 2007-11-05 | 2009-05-14 | Kyoto University | 新規ユビキリン結合性小分子 |
| GB0806527D0 (en) | 2008-04-11 | 2008-05-14 | Astex Therapeutics Ltd | Pharmaceutical compounds |
| KR102668696B1 (ko) | 2012-01-12 | 2024-05-29 | 예일 유니버시티 | E3 유비퀴틴 리가아제에 의한 표적 단백질 및 다른 폴리펩티드의 증진된 분해를 위한 화합물 및 방법 |
| EP3738594A1 (en) * | 2013-09-10 | 2020-11-18 | Madrigal Pharmaceuticals, Inc. | Targeted therapeutics having an hsp90 ligand as binding moiety |
| GB201502020D0 (en) | 2015-02-06 | 2015-03-25 | Cancer Rec Tech Ltd | Autotaxin inhibitory compounds |
| US20210275630A1 (en) | 2016-04-18 | 2021-09-09 | Phoremost Limited | Inactivation of dna repair as an anticancer therapy |
| MA45670A (fr) | 2016-07-13 | 2019-05-22 | Vertex Pharma | Procédés, compositions et kits pour augmenter l'efficacité d'édition du génome |
| EP3568128B1 (en) | 2017-01-12 | 2022-07-06 | The University of Kansas | Hsp90b n-terminal isoform-selective inhibitors |
| WO2019014600A1 (en) | 2017-07-13 | 2019-01-17 | Plex Pharmaceuticals, Inc. | TREATMENT OF ASSOCIATION FOR THE TREATMENT OF CANCER |
| WO2019118830A1 (en) * | 2017-12-14 | 2019-06-20 | Tarveda Therapeutics, Inc. | Hsp90-targeting conjugates and formulations thereof |
| EP3773670A4 (en) | 2018-04-05 | 2022-03-09 | Tarveda Therapeutics, Inc. | Hsp90-targeting conjugates and formulations thereof |
| CA3099155A1 (en) | 2018-05-14 | 2019-11-21 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| US11026963B2 (en) | 2018-07-11 | 2021-06-08 | Rubedo Life Sciences, Inc. | Senolytic compositions and uses thereof |
| GB201819126D0 (en) | 2018-11-23 | 2019-01-09 | Cancer Research Tech Ltd | Inhibitor compounds |
| AU2021211925A1 (en) | 2020-01-20 | 2022-08-25 | Neophore Limited | Isoindoline derivatives which bind to an ATP binding site |
| GB202008201D0 (en) | 2020-06-01 | 2020-07-15 | Neophore Ltd | Inhibitor compounds |
| GB202110373D0 (en) | 2021-07-19 | 2021-09-01 | Neophore Ltd | Inhibitor compounds |
| GB202300881D0 (en) | 2023-01-20 | 2023-03-08 | Neophore Ltd | Inhibitor compounds |
-
2021
- 2021-01-20 AU AU2021211925A patent/AU2021211925A1/en active Pending
- 2021-01-20 WO PCT/GB2021/050122 patent/WO2021148786A1/en not_active Ceased
- 2021-01-20 EP EP21702065.0A patent/EP4093731A1/en active Pending
- 2021-01-20 CA CA3168495A patent/CA3168495A1/en active Pending
- 2021-01-20 JP JP2022569300A patent/JP7671308B2/ja active Active
- 2021-01-20 US US17/793,912 patent/US12517130B2/en active Active
- 2021-01-20 CN CN202180023267.0A patent/CN115397811B/zh active Active
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