JP2023509263A - アフリベルセプトをコードするaav2バリアントを使用する眼内血管新生疾患を処置する方法 - Google Patents
アフリベルセプトをコードするaav2バリアントを使用する眼内血管新生疾患を処置する方法 Download PDFInfo
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- C07—ORGANIC CHEMISTRY
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- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14144—Chimeric viral vector comprising heterologous viral elements for production of another viral vector
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- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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US201962899070P | 2019-09-11 | 2019-09-11 | |
US62/899,070 | 2019-09-11 | ||
US201962913648P | 2019-10-10 | 2019-10-10 | |
US62/913,648 | 2019-10-10 | ||
PCT/US2019/062066 WO2021050094A1 (fr) | 2019-09-11 | 2019-11-18 | Méthodes de traitement de maladies néovasculaires oculaires à l'aide de variants d'aav2 codant pour l'aflibercept |
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JP2023509263A true JP2023509263A (ja) | 2023-03-08 |
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JP2022515693A Pending JP2023509263A (ja) | 2019-09-11 | 2019-11-18 | アフリベルセプトをコードするaav2バリアントを使用する眼内血管新生疾患を処置する方法 |
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EP (1) | EP4028037A4 (fr) |
JP (1) | JP2023509263A (fr) |
KR (1) | KR20220062352A (fr) |
CN (1) | CN114390928A (fr) |
AU (1) | AU2019465527A1 (fr) |
BR (1) | BR112022003206A2 (fr) |
CA (1) | CA3147843A1 (fr) |
IL (1) | IL291226A (fr) |
MX (1) | MX2022002960A (fr) |
Families Citing this family (1)
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JP2024515459A (ja) * | 2021-04-27 | 2024-04-10 | アドヴェラム バイオテクノロジーズ, インコーポレイテッド | アフリベルセプトをコードするaav2バリアントを使用する眼疾患の治療方法 |
Family Cites Families (2)
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KR102218265B1 (ko) * | 2016-06-16 | 2021-02-25 | 애드베룸 바이오테크놀로지스, 인코포레이티드 | Aav2 변이체를 아플리베르셉트와 함께 사용하는 amd의 치료 |
MX2019011040A (es) * | 2017-03-17 | 2020-01-20 | Adverum Biotechnologies Inc | Composiciones y metodos para potenciar la expresion genica. |
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2019
- 2019-11-18 BR BR112022003206A patent/BR112022003206A2/pt unknown
- 2019-11-18 JP JP2022515693A patent/JP2023509263A/ja active Pending
- 2019-11-18 EP EP19944875.4A patent/EP4028037A4/fr active Pending
- 2019-11-18 KR KR1020227011743A patent/KR20220062352A/ko unknown
- 2019-11-18 AU AU2019465527A patent/AU2019465527A1/en active Pending
- 2019-11-18 MX MX2022002960A patent/MX2022002960A/es unknown
- 2019-11-18 CN CN201980100210.9A patent/CN114390928A/zh active Pending
- 2019-11-18 CA CA3147843A patent/CA3147843A1/fr active Pending
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2022
- 2022-03-09 IL IL291226A patent/IL291226A/en unknown
Also Published As
Publication number | Publication date |
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CA3147843A1 (fr) | 2021-03-18 |
MX2022002960A (es) | 2022-04-06 |
BR112022003206A2 (pt) | 2022-08-16 |
EP4028037A1 (fr) | 2022-07-20 |
AU2019465527A1 (en) | 2022-03-10 |
IL291226A (en) | 2022-05-01 |
EP4028037A4 (fr) | 2023-06-28 |
CN114390928A (zh) | 2022-04-22 |
KR20220062352A (ko) | 2022-05-16 |
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