JP2023508173A5 - - Google Patents

Info

Publication number
JP2023508173A5
JP2023508173A5 JP2022539175A JP2022539175A JP2023508173A5 JP 2023508173 A5 JP2023508173 A5 JP 2023508173A5 JP 2022539175 A JP2022539175 A JP 2022539175A JP 2022539175 A JP2022539175 A JP 2022539175A JP 2023508173 A5 JP2023508173 A5 JP 2023508173A5
Authority
JP
Japan
Prior art keywords
antibody according
antibody
seq
cancer
fgfr2b
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022539175A
Other languages
English (en)
Japanese (ja)
Other versions
JP7686000B2 (ja
JP2023508173A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2020/138591 external-priority patent/WO2021129656A1/en
Publication of JP2023508173A publication Critical patent/JP2023508173A/ja
Publication of JP2023508173A5 publication Critical patent/JP2023508173A5/ja
Application granted granted Critical
Publication of JP7686000B2 publication Critical patent/JP7686000B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022539175A 2019-12-24 2020-12-23 新規抗FGFR2b抗体 Active JP7686000B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2019127903 2019-12-24
CNPCT/CN2019/127903 2019-12-24
PCT/CN2020/138591 WO2021129656A1 (en) 2019-12-24 2020-12-23 Novel anti-fgfr2b antibodies

Publications (3)

Publication Number Publication Date
JP2023508173A JP2023508173A (ja) 2023-03-01
JP2023508173A5 true JP2023508173A5 (enExample) 2024-01-05
JP7686000B2 JP7686000B2 (ja) 2025-05-30

Family

ID=76573701

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022539175A Active JP7686000B2 (ja) 2019-12-24 2020-12-23 新規抗FGFR2b抗体

Country Status (11)

Country Link
US (1) US20230052256A1 (enExample)
EP (1) EP4081539A4 (enExample)
JP (1) JP7686000B2 (enExample)
KR (1) KR20220119143A (enExample)
CN (1) CN114901687A (enExample)
AR (1) AR120884A1 (enExample)
AU (1) AU2020410863A1 (enExample)
CA (1) CA3160811A1 (enExample)
MX (1) MX2022007960A (enExample)
TW (1) TWI861325B (enExample)
WO (1) WO2021129656A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2023243773A1 (en) * 2022-03-28 2024-10-24 Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. Novel anti-fgfr2 antibodies.
CN117917435A (zh) * 2022-10-21 2024-04-23 北京天广实生物技术股份有限公司 结合fgfr2b的抗体及其用途
WO2024199362A1 (en) * 2023-03-31 2024-10-03 Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. Novel anti-FGFR2 antibodies
CN118994393A (zh) * 2023-05-19 2024-11-22 广东东阳光药业股份有限公司 一种抗fgfr2抗体及其应用
WO2025146131A1 (en) * 2024-01-05 2025-07-10 Beigene, Ltd. ANTI-FGFR2b ANTIBODIES, CONJUGATES AND METHODS OF USE
CN121319178A (zh) * 2024-07-02 2026-01-13 安博泰克药业有限公司 特异性结合FGFR2b的抗体及其与药物的缀合物

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1012259E (pt) * 1997-06-04 2009-11-06 Oxford Biomedica Ltd Vector dirigido a tumor
MXPA05009556A (es) * 2003-03-14 2005-11-16 Wyeth Corp Anticuerpos contra receptor de il-21 humano y sus usos.
AU2003271174A1 (en) * 2003-10-10 2005-04-27 Chugai Seiyaku Kabushiki Kaisha Double specific antibodies substituting for functional protein
SI1680140T1 (sl) * 2003-10-16 2011-08-31 Imclone Llc Inhibitorji receptorja-1 za fibroblastni rastni faktor in metode za zdravljenje z le-temi
US7371825B2 (en) * 2004-06-30 2008-05-13 Centocor, Inc. Anti-MCP-1 antibodies, compositions, methods and uses
US8101721B2 (en) * 2006-06-15 2012-01-24 Fibron Ltd. Antibodies blocking fibroblast growth factor receptor activation and methods of use thereof
DK3290052T3 (da) * 2008-11-07 2020-02-03 Galaxy Biotech Llc Monoklonale antistoffer mod fibroblastvækstfaktorreceptor 2
JP2014534806A (ja) * 2011-08-23 2014-12-25 ロシュ グリクアート アーゲー 抗mcsp抗体
AR088941A1 (es) * 2011-11-23 2014-07-16 Bayer Ip Gmbh Anticuerpos anti-fgfr2 y sus usos
MX2014007121A (es) * 2011-12-14 2014-09-04 Seattle Genetics Inc Nuevos conjugados de principio activo-ligante (adc) y su uso.
MX374785B (es) * 2013-08-01 2025-03-06 Five Prime Therapeutics Inc Anticuerpos anti-fgfr2iiib afucosilados.
CA2961439A1 (en) * 2014-11-05 2016-05-12 Genentech, Inc. Anti-fgfr2/3 antibodies and methods using same
SG10201913538VA (en) * 2015-11-23 2020-02-27 Five Prime Therapeutics Inc Fgfr2 inhibitors alone or in combination with immune stimulating agents in cancer treatment
US20170145086A1 (en) * 2015-11-25 2017-05-25 Visterra, Inc. Antibody molecules to april and uses thereof
IL266769B2 (en) * 2016-11-22 2024-04-01 Merck Patent Gmbh Monoclonal antibodies specific for fgfr1 and their preparation
WO2018095932A1 (en) * 2016-11-22 2018-05-31 Merck Patent Gmbh Monoclonal antibody directed to fgfr1
CN114846029A (zh) * 2019-12-24 2022-08-02 迪哲(江苏)医药股份有限公司 新颖抗fgfr2b抗体
JP7685999B2 (ja) * 2019-12-24 2025-05-30 ディザル(ジァンスー)ファーマシューティカル・カンパニー・リミテッド 新規抗FGFR2b抗体

Similar Documents

Publication Publication Date Title
JP2023508174A5 (enExample)
JP2023509402A5 (enExample)
CN110627906B (zh) 抗pd-l1/4-1bb双特异性抗体及其用途
JP7820383B2 (ja) グリピカン-3およびt細胞受容体を標的とする免疫グロブリン単一可変ドメインを含むポリペプチド
ES2773504T3 (es) Nuevo polipéptido que tiene afinidad por PD-L1
JP7821159B2 (ja) Bcmaと結合する単一可変ドメイン及び抗原結合分子
JP2024001073A5 (enExample)
CA2959671C (en) Anti-ck8 antibodies for use in the treatment of cancers
CN121909212A (zh) 抗cdh17抗体及其用途
CN119173540A (zh) 多特异性抗体及其用途
EP3418303A1 (en) ANTIBODY AGAINST EGFRvIII AND USE THEREOF
CA3208368A1 (en) Vegfa-binding molecules
AU2020326590A1 (en) Materials and methods for polymeric antibody receptor targeting
JP7821161B2 (ja) Bcmaと結合する単一可変ドメイン及び抗原結合分子
JP2022505144A5 (enExample)
CN120271715A (zh) 抗体及其药物偶联物和用途
CN112823168A (zh) 结合her2的四聚体多肽
CN117304324A (zh) 结合Claudin 18.2的结合部分及其应用
CN120379695A (zh) 使用Multabody治疗化疗抗性肿瘤
WO2025117871A1 (en) Bispecific tetravalent antibody targeting her2 and her3
WO2025117872A1 (en) Bispecific antibody-like protein and methods of making and using thereof
JP2024535691A5 (enExample)
CN116917331A (zh) 包含靶向磷脂酰肌醇蛋白聚糖-3和t细胞受体的免疫球蛋白单可变结构域的多肽
CN118488971A (zh) 优化的Multabody构建体、组合物和方法
CN116761887A (zh) 靶向SIRPα和PD-L1的双特异性抗体