JP2023505690A5 - - Google Patents
Info
- Publication number
- JP2023505690A5 JP2023505690A5 JP2022535116A JP2022535116A JP2023505690A5 JP 2023505690 A5 JP2023505690 A5 JP 2023505690A5 JP 2022535116 A JP2022535116 A JP 2022535116A JP 2022535116 A JP2022535116 A JP 2022535116A JP 2023505690 A5 JP2023505690 A5 JP 2023505690A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- compound
- group
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962946100P | 2019-12-10 | 2019-12-10 | |
| US62/946,100 | 2019-12-10 | ||
| PCT/US2020/064191 WO2021119242A1 (en) | 2019-12-10 | 2020-12-10 | Replication protein a (rpa)-dna interaction inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023505690A JP2023505690A (ja) | 2023-02-10 |
| JP2023505690A5 true JP2023505690A5 (cg-RX-API-DMAC7.html) | 2023-12-14 |
| JP7677646B2 JP7677646B2 (ja) | 2025-05-15 |
Family
ID=76330773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022535116A Active JP7677646B2 (ja) | 2019-12-10 | 2020-12-10 | 複製タンパク質ａ（ｒｐａ）－ｄｎａ相互作用阻害剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12486246B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP4073055B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP7677646B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112022011372A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3162280A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2021119242A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017205503A1 (en) | 2016-05-24 | 2017-11-30 | Indiana University Research And Technology Corporation | Ku inhibitors and their use |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070196395A1 (en) | 2003-12-12 | 2007-08-23 | Mackerell Alexander | Immunomodulatory compounds that target and inhibit the py'binding site of tyrosene kinase p56 lck sh2 domain |
| JP2008515992A (ja) * | 2004-10-13 | 2008-05-15 | ピーティーシー セラピューティクス，インコーポレーテッド | 体細胞変異に起因する疾患の阻止／治療用医薬を製造するための規定化合物の使用 |
| EP1905762A1 (en) | 2005-05-30 | 2008-04-02 | Genecare Research Institute Co., Ltd | Pyrazolone derivative |
| US20100055116A1 (en) | 2006-04-13 | 2010-03-04 | Liou Hsiou-Chi | Methods and Compositions for Targeting c-Rel |
| WO2008045663A2 (en) * | 2006-10-06 | 2008-04-17 | Kalypsys, Inc. | Aryl-substituted heterocyclic pde4 inhibitors as antiinflammatory agents |
| PT2139484E (pt) | 2007-04-10 | 2013-10-31 | Exelixis Inc | Métodos de tratamento de cancro usando inibidores piridopirimidinona de pi3k-alfa |
| US20100249165A1 (en) | 2007-06-08 | 2010-09-30 | University Of Copenhagen | Pdz domain modulators |
| WO2008157680A2 (en) | 2007-06-21 | 2008-12-24 | The Wistar Institute | Methods and compositions for modulating p300/cbp activity |
| ES2585157T3 (es) | 2007-09-27 | 2016-10-04 | Dow Agrosciences Llc | Proteínas de dedo de cinc de diseño que se dirigen a los genes de 5-enolpiruvil shikimato-3-fosfato sintasa |
| US8716283B2 (en) | 2007-11-07 | 2014-05-06 | University Of Massachusetts | Type III secretion inhibitors, analogs and uses thereof |
| WO2009146179A1 (en) | 2008-04-15 | 2009-12-03 | University Of Iowa Research Foundation | Zinc finger nuclease for the cftr gene and methods of use thereof |
| US9005670B2 (en) | 2010-01-05 | 2015-04-14 | The Johns Hopkins University | Use of histone acetyltransferase inhibitors as novel anti-cancer therapies |
| CA2825680C (en) * | 2010-02-05 | 2019-12-03 | Indiana University Research And Technology Corporation | Materials and method for inhibiting replication protein a and uses thereof |
| US8980955B2 (en) | 2010-09-17 | 2015-03-17 | Indiana University Research And Technology | Small molecule inhibitors of replication protein A that also act synergistically with cisplatin |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| KR102955556B1 (ko) | 2012-12-12 | 2026-04-22 | 더 브로드 인스티튜트, 인코퍼레이티드 | 서열 조작을 위한 crispr-cas 성분 시스템, 방법 및 조성물 |
| US10227610B2 (en) | 2013-02-25 | 2019-03-12 | Sangamo Therapeutics, Inc. | Methods and compositions for enhancing nuclease-mediated gene disruption |
| EP3022304B1 (en) | 2013-07-19 | 2018-12-26 | Larix Biosciences LLC | Methods and compositions for producing double allele knock outs |
| US20150044772A1 (en) | 2013-08-09 | 2015-02-12 | Sage Labs, Inc. | Crispr/cas system-based novel fusion protein and its applications in genome editing |
| ITMI20131410A1 (it) | 2013-08-26 | 2015-02-27 | Univ Degli Studi Modena E Reggio Emilia | Composti e composizioni per l'uso nella inibizione dell' interazione lbc-rhoa |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US10774063B2 (en) * | 2014-11-13 | 2020-09-15 | Indiana University Research And Technology Corporation | Materials and method for inhibiting replication protein A and uses thereof |
| WO2017205503A1 (en) | 2016-05-24 | 2017-11-30 | Indiana University Research And Technology Corporation | Ku inhibitors and their use |
| CA3075734A1 (en) | 2017-09-19 | 2019-03-28 | Indiana University Research And Technology Corporation | Xpa inhibitor compounds and their use |
-
2020
- 2020-12-10 WO PCT/US2020/064191 patent/WO2021119242A1/en not_active Ceased
- 2020-12-10 EP EP20897908.8A patent/EP4073055B1/en active Active
- 2020-12-10 US US17/782,876 patent/US12486246B2/en active Active
- 2020-12-10 CA CA3162280A patent/CA3162280A1/en active Pending
- 2020-12-10 BR BR112022011372A patent/BR112022011372A2/pt unknown
- 2020-12-10 JP JP2022535116A patent/JP7677646B2/ja active Active
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