JP2023504697A - Cosmetic compositions and uses thereof, and methods for improving sensory properties - Google Patents
Cosmetic compositions and uses thereof, and methods for improving sensory properties Download PDFInfo
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- JP2023504697A JP2023504697A JP2022533438A JP2022533438A JP2023504697A JP 2023504697 A JP2023504697 A JP 2023504697A JP 2022533438 A JP2022533438 A JP 2022533438A JP 2022533438 A JP2022533438 A JP 2022533438A JP 2023504697 A JP2023504697 A JP 2023504697A
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- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 229940010747 sodium hyaluronate Drugs 0.000 description 1
- 229940045920 sodium pyrrolidone carboxylate Drugs 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
- HYRLWUFWDYFEES-UHFFFAOYSA-M sodium;2-oxopyrrolidine-1-carboxylate Chemical compound [Na+].[O-]C(=O)N1CCCC1=O HYRLWUFWDYFEES-UHFFFAOYSA-M 0.000 description 1
- 229950006451 sorbitan laurate Drugs 0.000 description 1
- 235000011067 sorbitan monolaureate Nutrition 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 229940100459 steareth-20 Drugs 0.000 description 1
- 229940094908 stearyl myristate Drugs 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- TUNFSRHWOTWDNC-UHFFFAOYSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 description 1
- HBPNTDBLHQHPLH-UHFFFAOYSA-N tetradecyl 16-methylheptadecanoate Chemical compound CCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCCCC(C)C HBPNTDBLHQHPLH-UHFFFAOYSA-N 0.000 description 1
- AVKVDDQTHIQFSC-UHFFFAOYSA-N tetradecyl docosanoate Chemical compound CCCCCCCCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCC AVKVDDQTHIQFSC-UHFFFAOYSA-N 0.000 description 1
- DHZWALZKPWZSMA-UHFFFAOYSA-N tetradecyl oleate Natural products CCCCCCCCCCCCCCOC(=O)CCCCCCCC=CCCCCCCCC DHZWALZKPWZSMA-UHFFFAOYSA-N 0.000 description 1
- DZKXJUASMGQEMA-UHFFFAOYSA-N tetradecyl tetradecanoate Chemical compound CCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCC DZKXJUASMGQEMA-UHFFFAOYSA-N 0.000 description 1
- 239000010678 thyme oil Substances 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 229960000984 tocofersolan Drugs 0.000 description 1
- AOBORMOPSGHCAX-DGHZZKTQSA-N tocofersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2O[C@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-DGHZZKTQSA-N 0.000 description 1
- 229940042585 tocopherol acetate Drugs 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- ZCIHMQAPACOQHT-ZGMPDRQDSA-N trans-isorenieratene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/c1c(C)ccc(C)c1C)C=CC=C(/C)C=Cc2c(C)ccc(C)c2C ZCIHMQAPACOQHT-ZGMPDRQDSA-N 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- HTJNEBVCZXHBNJ-XCTPRCOBSA-H trimagnesium;(2r)-2-[(1s)-1,2-dihydroxyethyl]-3,4-dihydroxy-2h-furan-5-one;diphosphate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.OC[C@H](O)[C@H]1OC(=O)C(O)=C1O HTJNEBVCZXHBNJ-XCTPRCOBSA-H 0.000 description 1
- 229940117985 trimethyl pentaphenyl trisiloxane Drugs 0.000 description 1
- 235000013799 ultramarine blue Nutrition 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
- 239000002888 zwitterionic surfactant Substances 0.000 description 1
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
- GZIFEOYASATJEH-VHFRWLAGSA-N δ-tocopherol Chemical compound OC1=CC(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1 GZIFEOYASATJEH-VHFRWLAGSA-N 0.000 description 1
Classifications
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- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
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Abstract
本発明は、化粧品組成物であって、それぞれ化粧品組成物の総重量に基づいて、(a)0.01wt%~2.0wt%の少なくとも1種のゲル形成(メタ)アクリルポリマー、(b)脂肪酸のポリエチレングリコールジエステル、脂肪酸のポリプロピレングリコールジエステル、及び脂肪酸のポリ(エチレン-co-プロピレングリコール)ジエステルからなる群から選択される、0.01wt%~1.0wt%(1.0wt%を除く)の少なくとも1種の非イオン性乳化剤、(c)0.01wt%~1.0wt%の、12~20の範囲内のHLB値を有する少なくとも1種の可溶化剤、並びに(d)水、を含み、前記組成物が、ゲル又は水中油型エマルションの形態であり、好ましくはゲルの形態である、化粧品組成物を提供する。本発明の化粧品組成物は、さっぱりとしており、油っぽくなく、より広げやすい形態である。【選択図】なしThe present invention provides a cosmetic composition comprising (a) 0.01 wt% to 2.0 wt% of at least one gel-forming (meth)acrylic polymer, (b) a fatty acid, each based on the total weight of the cosmetic composition. 0.01 wt% to 1.0 wt% (excluding 1.0 wt%) of at least one selected from the group consisting of polyethylene glycol diesters, polypropylene glycol diesters of fatty acids, and poly(ethylene-co-propylene glycol) diesters of fatty acids comprising a nonionic emulsifier, (c) 0.01 wt% to 1.0 wt% of at least one solubilizer having an HLB value within the range of 12 to 20, and (d) water, wherein the composition comprises A cosmetic composition is provided in the form of a gel or an oil-in-water emulsion, preferably in the form of a gel. The cosmetic composition of the present invention is refreshing, non-greasy and in a more spreadable form. [Selection figure] None
Description
本発明は、ゲル又は水中油型エマルションの形態の化粧品組成物及びその使用、並びに該化粧品組成物を皮膚上に塗布することによる官能特性を改善する方法に関する。 The present invention relates to cosmetic compositions in the form of gels or oil-in-water emulsions and their use, as well as to methods for improving sensory properties by applying said cosmetic compositions onto the skin.
皮膚は、健常な状態を維持するために保湿を必要とする。現在までのところ、保湿製品が根本的な対策である。化粧品及びパーソナルケア市場には、特許出願WO2005/095462及びFR2902333に記載されるものなどの多くの保湿製品が存在する。皮膚保湿製品は、化粧水、ミルク、クリーム、フェイシャルマスク、エッセンス、ハイドレーターなどに分類することができる。 Skin needs moisturization to stay healthy. So far, moisturizing products have been the primary remedy. There are many moisturizing products in the cosmetic and personal care market, such as those described in patent applications WO2005/095462 and FR2902333. Skin moisturizing products can be classified into lotions, milks, creams, facial masks, essences, hydrators, and so on.
CN 110192999Aは、油中水型のリン酸ジミリスチル乳化剤0.2%~0.5%、水中油型PPG-10セチルエーテルリン酸1%~2%、及び(アクリレーツ/メタクリル酸ベヘネス-25)コポリマー1%~1.5%を含む、O/W(水中油型)の形態のメイクアップベースを開示している。前記メイクアップベースは、さっぱりとした感触及び保湿効果を生じることができる。しかし、前記メイクアップベースはクリーム状の外観を有するために、消費者にはあまり魅力的ではない。 CN 110192999A contains 0.2%-0.5% water-in-oil dimyristyl phosphate emulsifier, 1%-2% oil-in-water PPG-10 cetyl ether phosphate, and 1%-1.5 acrylates/beheneth-25 methacrylate copolymer. %, in the form of O/W (oil-in-water). The make-up base can produce a refreshing feel and a moisturizing effect. However, said make-up bases are not very appealing to consumers due to their creamy appearance.
CN 109172386Aは、以下の構成成分:100~500ppmのオリゴペプチド、1~10%のスベリヒユエキス、1~5%のカモミールエキス、0.2~1%の石菖蒲(rhizoma acori tatarinowii)の揮発油、10~30%のポリアクリル酸グリセリル(glycerol polyacrylate)、1~5%のプロピレングリコール、1~5%のグリセロール、0.1~0.5%のp-ヒドロキシアセトフェノン、0.1~0.5%のオクチルグリコール、及び残りの脱イオン水を質量百分率で含む、複合保湿ヒドロゲルを開示している。この文献は、保湿製品でのポリアクリレートの使用について言及している。しかし、前記複合ヒドロゲルは高ポリマー含有量を有し、それによって油っぽい感触が強くなる。 CN 109172386A contains the following components: 100-500 ppm oligopeptides, 1-10% purslane extract, 1-5% chamomile extract, 0.2-1% rhizoma acori tatarinowii volatile oil, 10-10% 30% glycerol polyacrylate, 1-5% propylene glycol, 1-5% glycerol, 0.1-0.5% p-hydroxyacetophenone, 0.1-0.5% octyl glycol, and the balance deionized A composite moisturizing hydrogel is disclosed that contains a weight percentage of water. This document mentions the use of polyacrylates in moisturizing products. However, the composite hydrogels have a high polymer content, which makes them feel greasy.
KR 20180102827Aは、自己組織化ゲル特性を有する、親水性に変性された脂質巨大分子から調製されたヒドロゲル型保湿化粧品組成物を開示している。前記組成物は、組成物の総重量に基づいて1~15%の親水性に変性された脂質ポリマーを含む。前記組成物は、水溶性又は油溶性活性成分の経皮吸収を促進する強い皮膚保護膜を形成することができる。しかし、前記組成物はやはり高ポリマー含有量を有し、それによって皮膚感触に負の影響を引き起こし得る。 KR 20180102827A discloses hydrogel-type moisturizing cosmetic compositions prepared from hydrophilically modified lipid macromolecules with self-assembled gel properties. The composition contains 1-15% hydrophilically modified lipid polymer, based on the total weight of the composition. Said composition is capable of forming a strong protective skin film that facilitates percutaneous absorption of water-soluble or oil-soluble active ingredients. However, said compositions still have a high polymer content, which can cause a negative effect on skin feel.
上の文献に記載されるような製品は、幾つかの点、例えば、保湿率、さっぱりとした感触、展延性、外観などにおいて常に不満足である。したがって、上の欠点を克服することができる改善された化粧品組成物を得ること、及び化粧品組成物を皮膚上に塗布することによる官能特性を改善する方法を開発することが依然として求められている。 Products such as those described in the above references are consistently unsatisfactory in several respects, such as moisture retention, refreshing feel, spreadability, appearance, and the like. Therefore, there remains a need to obtain improved cosmetic compositions that can overcome the above drawbacks and to develop methods for improving the sensory properties of applying cosmetic compositions onto the skin.
本発明者らは、驚くべきことに、非イオン性乳化剤を12~20の範囲内のHLB値を有する可溶化剤と組み合わせると、より少ない量のゲル形成(メタ)アクリルポリマーを含む化粧品組成物を調製することが可能になることを見出した。加えて、該化粧品組成物は、さっぱりとしており、油っぽくなく、より広げやすい。 The inventors have surprisingly found that when a nonionic emulsifier is combined with a solubilizer having an HLB value within the range of 12 to 20, a cosmetic composition containing a lower amount of gel-forming (meth)acrylic polymer It has been found that it is possible to prepare In addition, the cosmetic composition is refreshing, non-greasy and easier to spread.
第1の態様では、本発明は、化粧品組成物であって、
それぞれ化粧品組成物の総重量に基づいて、
(a) 0.01wt%~2.0wt%の少なくとも1種のゲル形成(メタ)アクリルポリマー、
(b) 脂肪酸のポリエチレングリコール(以降、PEGと呼ぶ)ジエステル、脂肪酸のポリプロピレングリコール(以降、PPGと呼ぶ)ジエステル、及び脂肪酸のポリ(エチレン-co-プロピレングリコール)ジエステルからなる群から選択される、0.01wt%~1.0wt%(1.0wt%を除く)の少なくとも1種の非イオン性乳化剤、
(c) 0.01wt%~1.0wt%の、12~20の範囲内のHLB値を有する少なくとも1種の可溶化剤、並びに
(d) 水、
を含み、
前記組成物が、ゲル又は水中油型エマルションの形態であり、好ましくはゲルの形態である、
化粧品組成物を提供する。
In a first aspect, the present invention provides a cosmetic composition comprising
Based on the total weight of the cosmetic composition, respectively,
(a) 0.01 wt% to 2.0 wt% of at least one gel-forming (meth)acrylic polymer;
(b) selected from the group consisting of polyethylene glycol (hereinafter referred to as PEG) diesters of fatty acids, polypropylene glycol (hereinafter referred to as PPG) diesters of fatty acids, and poly(ethylene-co-propylene glycol) diesters of fatty acids; 0.01 wt% to 1.0 wt% (excluding 1.0 wt%) of at least one nonionic emulsifier;
(c) from 0.01 wt% to 1.0 wt% of at least one solubilizer with an HLB value within the range of 12 to 20, and
(d) water;
including
said composition is in the form of a gel or an oil-in-water emulsion, preferably in the form of a gel;
A cosmetic composition is provided.
第2の態様では、本発明は、パーソナルケア製品を調製するための上述の化粧品組成物の使用を提供する。 In a second aspect, the invention provides the use of a cosmetic composition as defined above for preparing a personal care product.
第3の態様では、本発明は、該化粧品組成物を皮膚の少なくとも1部分上に塗布することによる官能特性を改善する方法を提供する。 In a third aspect, the present invention provides a method of improving organoleptic properties by applying said cosmetic composition onto at least a portion of the skin.
本発明の化粧品組成物は、ゲル又は水中油型エマルションの形態であり、これは消費者にとって魅力的である。その上、少量のポリマーを含むゲル又は水中油型エマルションの形態である本発明の化粧品組成物は、さっぱりしており、油っぽくなく、より広げやすい。ゲルは塗布しやすく、液体よりむらなく正確にカバーし、粉末のように皮膚を乾燥させることがないために、ゲルの形態の化粧品組成物が好ましい。 The cosmetic compositions of the present invention are in the form of gels or oil-in-water emulsions, which are appealing to consumers. Moreover, the cosmetic compositions of the present invention in the form of gels or oil-in-water emulsions containing a small amount of polymer are refreshing, non-greasy and easier to spread. Cosmetic compositions in the form of gels are preferred because gels are easier to apply, provide more even and precise coverage than liquids, and do not dry the skin like powders do.
本発明の態様は、以降に示す詳細な説明から明らかになろう。詳細な説明及び具体例は、本発明の好ましい実施形態を示すものであるが、例示のみを目的とすることを意図しており、本発明の範囲を限定することを意図するものではないことが理解されるべきである。 Aspects of the invention will become apparent from the detailed description provided hereinafter. It should be understood that the detailed description and specific examples, while indicating preferred embodiments of the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention. should be understood.
好ましい実施形態の以下の説明は、本来例示的なものに過ぎず、本発明、その用途、又は使用を限定することを意図するものでは決してない。 The following description of preferred embodiments is merely exemplary in nature and is in no way intended to limit the invention, its applications, or uses.
本明細書を通して、範囲は、その範囲内のありとあらゆる値を記載するための略記として使用される。範囲内のいかなる値も範囲の端点として選択することができる。別段の指定がない限り、本明細書及び説明における他の箇所に表現されるすべての百分率及び量は、重量による百分率を指すと理解されるべきである。例えば、記号「wt%」は、重量による百分率を意味する。 Ranges are used throughout this specification as shorthand to describe each and every value within the range. Any value within the range can be selected as the endpoint of the range. All percentages and amounts expressed elsewhere in the specification and description should be understood to refer to percentages by weight, unless otherwise specified. For example, the symbol "wt%" means percentage by weight.
一態様では、本発明は、化粧品組成物であって、
それぞれ化粧品組成物の総重量に基づいて、
(a) 0.01wt%~2.0wt%の少なくとも1種のゲル形成(メタ)アクリルポリマー、
(b) 脂肪酸のポリエチレングリコールジエステル、脂肪酸のポリプロピレングリコールジエステル、及び脂肪酸のポリ(エチレン-co-プロピレングリコール)ジエステルからなる群から選択される、0.01wt%~1.0wt%(1.0wt%を除く)の少なくとも1種の非イオン性乳化剤、
(c) 0.01wt%~1.0wt%の、12~20の範囲内のHLB値を有する少なくとも1種の可溶化剤、並びに
(d) 水、
を含み、
前記組成物が、ゲル又は水中油型エマルションの形態であり、好ましくはゲルの形態である、
化粧品組成物を提供する。
In one aspect, the present invention is a cosmetic composition comprising:
Based on the total weight of the cosmetic composition, respectively,
(a) 0.01 wt% to 2.0 wt% of at least one gel-forming (meth)acrylic polymer;
(b) 0.01 wt% to 1.0 wt% (excluding 1.0 wt%) selected from the group consisting of polyethylene glycol diesters of fatty acids, polypropylene glycol diesters of fatty acids, and poly(ethylene-co-propylene glycol) diesters of fatty acids; at least one nonionic emulsifier of
(c) from 0.01 wt% to 1.0 wt% of at least one solubilizer with an HLB value within the range of 12 to 20, and
(d) water;
including
said composition is in the form of a gel or an oil-in-water emulsion, preferably in the form of a gel;
A cosmetic composition is provided.
本明細書で使用される場合、「ゲル」という用語は、体表面、例えば皮膚に塗布される製剤を指す。ゲルは、軟質で弱いものから硬質で丈夫なものまで及ぶ性質を有することができる固体及び/又はゼリー様材料である。ゲルは、定常状態では流動性を示さない、実質的に希薄な架橋系であると定義される。 As used herein, the term "gel" refers to a formulation that is applied to a body surface, such as the skin. Gels are solid and/or jelly-like materials that can have properties ranging from soft and weak to hard and tough. A gel is defined as a substantially dilute crosslinked system that does not flow at steady state.
本明細書で使用される場合、「水中油型エマルション」という用語は、油(分散相)が水溶液(連続相)中に分散した二つの不混和相の混合物の総称として使用される。 As used herein, the term "oil-in-water emulsion" is used generically to a mixture of two immiscible phases in which oil (dispersed phase) is dispersed in an aqueous solution (continuous phase).
ある実施形態では、本発明に使用されるゲル形成(メタ)アクリルポリマーは、特に、親水性(メタ)アクリルポリマーであってもよく、好ましくは、完全に中和された又は少なくとも部分的に中和された(メタ)アクリルホモポリマー又はコポリマーから選択される。 In one embodiment, the gel-forming (meth)acrylic polymer used in the present invention may in particular be a hydrophilic (meth)acrylic polymer, preferably fully neutralized or at least partially neutralized. selected from blended (meth)acrylic homopolymers or copolymers.
ある実施形態では、本発明に使用されるゲル形成(メタ)アクリルポリマーは、例えば、(メタ)アクリルホモポリマー又はコポリマーの塩(ナトリウム塩又はカリウム塩など)であってもよく、限定するものではないが挙げることのできる例は、ポリアクリル酸ナトリウム(BASF製のCosmedia(登録商標)SP、Cosmedia(登録商標)ACE、及びCosmedia(登録商標)SPLなど)、少なくとも1種の極性油を含む逆エマルションの形態の部分的に中和されたポリアクリル酸ナトリウム(BASF製のLuvigel(登録商標)EMなど)である。 In one embodiment, the gel-forming (meth)acrylic polymer used in the present invention may be, for example, a salt (such as a sodium or potassium salt) of a (meth)acrylic homopolymer or copolymer, but is not limited to Examples that may be mentioned, although not included, are sodium polyacrylates (such as Cosmedia® SP, Cosmedia® ACE and Cosmedia® SPL from BASF), inverse gels containing at least one polar oil. Partially neutralized sodium polyacrylate in the form of an emulsion (such as Luvigel® EM from BASF).
ある実施形態では、ゲル形成(メタ)アクリルポリマーには、末端に疎水基を有する親水性ポリアルコキシドセグメントを含むポリ(メタ)アクリル酸も含まれてもよい。ポリアルコキシドセグメントは、通常、分子の一端にあるエチレン不飽和結合と他端にある末端疎水基の間に位置するポリエチレンオキシド単位若しくはポリプロピレンオキシド単位又はそれらの組み合わせからなる。疎水基は、8~30個の炭素原子を含有する長鎖炭化水素基から選択することができる。これらのポリマーの非限定的な例として、Tinovis(登録商標)GTC(INCI:(アクリレーツ/メタクリル酸ベヘネス-25)コポリマー)、Aculyn(登録商標)22(INCI:(アクリレーツ/メタクリル酸ステアレス-20)コポリマー)、Aculyn(登録商標)88(INCI:(アクリレーツ/メタクリル酸ステアレス-20)クロスポリマー、(アクリレーツ/イタコン酸ステアレス-20)コポリマー(Acrylated/Steareth-20 Itaconate copolymer)、(アクリレーツ/イタコン酸セテス-20)コポリマー(Acrylate/Ceteth-20 Itaconate copolymer)、及びアクリレーツ/パルメス25)が挙げられる。 In some embodiments, the gel-forming (meth)acrylic polymer may also include poly(meth)acrylic acid comprising hydrophilic polyalkoxide segments terminated with hydrophobic groups. A polyalkoxide segment usually consists of polyethylene oxide or polypropylene oxide units or a combination thereof located between an ethylenically unsaturated bond at one end of the molecule and a terminal hydrophobic group at the other end. Hydrophobic groups can be selected from long chain hydrocarbon groups containing 8 to 30 carbon atoms. Non-limiting examples of these polymers include Tinovis® GTC (INCI: (Acrylates/Beheneth-25 methacrylate) copolymer), Aculyn® 22 (INCI: (Acrylates/Steareth-20 methacrylate) Aculyn® 88 (INCI: (Acrylate/Steareth-20 Methacrylate) Crosspolymer, (Acrylate/Steareth-20 Itaconate Copolymer), (Acrylate/Ceteth Itaconate) -20) copolymer (Acrylate/Ceteth-20 Itaconate copolymer), and Acrylates/Palmes 25).
ある実施形態では、本発明に使用されるゲル形成(メタ)アクリルポリマーは一般に、10,000~1,000,000ダルトン、好ましくは15,000~750,000ダルトン、より好ましくは20,000~500,000ダルトン、最も好ましくは25,000~250,000ダルトンの範囲内の重量平均分子量を有し、これは従来の技法、例えばGPCによって測定することができる。 In one embodiment, gel-forming (meth)acrylic polymers used in the present invention generally range from 10,000 to 1,000,000 daltons, preferably from 15,000 to 750,000 daltons, more preferably from 20,000 to 500,000 daltons, and most preferably from 25,000 to 250,000 daltons. weight average molecular weight, which can be measured by conventional techniques such as GPC.
ある実施形態では、化粧品組成物の総重量に基づいて、ゲル形成(メタ)アクリルポリマーは、0.05wt%~2.0wt%、0.05wt%~1.8wt%、0.05wt%~1.5wt%、0.1wt%~1.5wt%、0.2wt%~1.2wt%、0.3wt%~1.2wt%、0.4wt%~1.2wt%の量で存在し得る。 In some embodiments, based on the total weight of the cosmetic composition, the gel-forming (meth)acrylic polymer is 0.05 wt% to 2.0 wt%, 0.05 wt% to 1.8 wt%, 0.05 wt% to 1.5 wt%, 0.1 wt% % to 1.5 wt%, 0.2 wt% to 1.2 wt%, 0.3 wt% to 1.2 wt%, 0.4 wt% to 1.2 wt%.
ある実施形態では、本発明に適した非イオン性乳化剤は、好ましくは、極性の中央部分及び非極性の末端部分を有するものである。中央部分は、例えば、末端が脂肪酸でエステル化された長鎖エチレンオキシド単位からなる。本発明に使用される非イオン性乳化剤は、脂肪酸のポリエチレングリコールジエステル(以降、PEG-n-ジエステルと呼ぶ)、脂肪酸のポリプロピレングリコールジエステル(以降、PPG-mジエステルと呼ぶ)、及び脂肪酸のポリ(エチレン-co-プロピレングリコール)ジエステル(以降、PEG/PPG-p/qジエステルと呼ぶ)からなる群から選択されてもよく、前記脂肪酸は、8~30個の炭素原子、好ましくは12~30個の炭素原子、より好ましくは12~24個の炭素原子を有する飽和又は不飽和脂肪酸であり得る。 In one embodiment, nonionic emulsifiers suitable for the present invention preferably have a polar central portion and non-polar terminal portions. The central portion consists, for example, of long-chain ethylene oxide units terminally esterified with fatty acids. The nonionic emulsifiers used in the present invention include polyethylene glycol diesters of fatty acids (hereinafter referred to as PEG-n-diesters), polypropylene glycol diesters of fatty acids (hereinafter referred to as PPG-m diesters), and poly( ethylene-co-propylene glycol) diesters (hereinafter referred to as PEG/PPG-p/q diesters), said fatty acids having 8-30 carbon atoms, preferably 12-30 carbon atoms, more preferably saturated or unsaturated fatty acids having 12 to 24 carbon atoms.
本発明に適した非イオン性乳化剤は、PEG-nジエステル、PPG-mジエステル、及びPEG/PPG-p/qジエステルであり得、ここで、nは30~250、好ましくは60~200、より好ましくは90~150であり、mは10~50、好ましくは20~40であり、pは10~50、好ましくは20~40であり、qは1~10、好ましくは1~5である。好ましくは、前記ジエステルは、例えば、ジラウリン酸エステル、ジベヘン酸エステル、ジステアリン酸エステル、ジイソステアリン酸エステル、ジオレイン酸エステル及びジリシノール酸エステル、ジミリスチン酸エステル(dimyritate)、ジパルミチン酸エステル、より好ましくは、ジラウリン酸エステル、ジステアリン酸エステル、及びジイソステアリン酸エステル、最も好ましくはジステアリン酸エステルを含んでもよい。そのような非イオン性乳化剤の例は、ジステアリン酸PEG-32、ジステアリン酸PEG-75、ジステアリン酸PEG-120、ジステアリン酸PEG-150(BASF製のEumulgin(登録商標)EO 33)、ジステアリン酸PEG-175、ジステアリン酸PEG-190、ジステアリン酸PEG-250、ジリシノール酸PEG/PPG-32/3及びジオレイン酸PPG-30、ジベヘン酸PEG-150、ジイソステアリン酸PEG-90、ジイソステアリン酸PEG-175、ジオレイン酸PEG-150、並びにジオレイン酸PEG-120メチルグルコースである。 Nonionic emulsifiers suitable for the present invention can be PEG-n diesters, PPG-m diesters and PEG/PPG-p/q diesters, where n is 30-250, preferably 60-200 and more. Preferably 90-150, m is 10-50, preferably 20-40, p is 10-50, preferably 20-40, q is 1-10, preferably 1-5. Preferably, said diesters are, for example, dilaurates, dibehenates, distearates, diisostearates, dioleates and diricinoleates, dimyritates, dipalmitates, more preferably Dilaurates, distearates, and diisostearates, most preferably distearates, may also be included. Examples of such nonionic emulsifiers are PEG-32 distearate, PEG-75 distearate, PEG-120 distearate, PEG-150 distearate (Eumulgin® EO 33 from BASF), PEG distearate -175, PEG-190 Distearate, PEG-250 Distearate, PEG/PPG-32/3 Diricinoleate and PPG-30 Dioleate, PEG-150 Dibehenate, PEG-90 Diisostearate, PEG-175 Diisostearate, Diolein PEG-150 acid, and PEG-120 methylglucose dioleate.
ある実施形態では、本発明に使用される非イオン性乳化剤は一般に、1500~12000ダルトン、好ましくは2000~10000ダルトン、より好ましくは3000~9000ダルトン、最も好ましくは4000~8000ダルトン、とりわけ好ましくは4000~7000ダルトンの範囲内の重量平均分子量を有する。 In one embodiment, the nonionic emulsifiers used in the present invention are generally 1500-12000 Daltons, preferably 2000-10000 Daltons, more preferably 3000-9000 Daltons, most preferably 4000-8000 Daltons, especially preferably 4000 Daltons. It has a weight average molecular weight in the range of ~7000 Daltons.
ある実施形態では、化粧品組成物の総重量に基づいて、非イオン性乳化剤は、0.02wt%~0.9wt%、0.03wt%~0.8wt%、0.04wt%~0.7wt%、0.05wt%~0.6wt%、0.06wt%~0.5wt%、0.07wt%~0.4wt%、0.08wt%~0.3wt%、好ましくは0.07wt%~0.4wt%、より好ましくは0.08wt%~0.3wt%、最も好ましくは0.1wt%の量で存在し得る。 In some embodiments, based on the total weight of the cosmetic composition, the nonionic emulsifier is present at 0.02 wt% to 0.9 wt%, 0.03 wt% to 0.8 wt%, 0.04 wt% to 0.7 wt%, 0.05 wt% to 0.6 wt%. wt%, 0.06 wt% to 0.5 wt%, 0.07 wt% to 0.4 wt%, 0.08 wt% to 0.3 wt%, preferably 0.07 wt% to 0.4 wt%, more preferably 0.08 wt% to 0.3 wt%, most preferably may be present in an amount of 0.1 wt%.
ある実施形態では、本発明に使用される可溶化剤は、好ましくは15~20の範囲内のHLB値を有し得る。適切な可溶化剤は、非イオン性乳化剤、とりわけ、ポリアルキレンオキシド部分、脂肪酸又は脂肪アルコールの残基、及び場合により脂肪族多価アルコールの残基を連結基として含有する非イオン性界面活性剤を含んでもよい。好ましくは、ポリアルキレンオキシドは、大抵の場合ポリエチレンオキシドであり、又はポリプロピレンオキシド若しくは混合ポリエチレンオキシド/プロピレンオキシドである。一般に、可溶化剤は、3~100個の、とりわけ5~80個のアルキレンオキシド単位を含有する。脂肪酸又は脂肪アルコールは、大抵の場合8~24個、とりわけ12~24個の炭素原子を含有し、多くの場合、直鎖状である。本発明に使用される12~20の範囲内のHLB値を有する可溶化剤は、脂肪アルコールのポリエチレングリコールエーテル、水添ヒマシ油のポリエチレングリコールエーテル、ソルビタンエステルのポリエチレングリコール誘導体、ポリソルベート、グリセロールエステル、グリセロールエステルのポリエチレングリコール誘導体、リン酸アルキル、及び硫酸アルキルなどからなる群から選択されてもよい。有用な非イオン性乳化剤のさらなる例は、CTFA Cosmetic Ingredient Handbook、第2版、1990年に列挙されている。 In one embodiment, the solubilizer used in the present invention may have an HLB value preferably within the range of 15-20. Suitable solubilizers are nonionic emulsifiers, especially nonionic surfactants containing as linking groups polyalkylene oxide moieties, residues of fatty acids or fatty alcohols, and optionally residues of fatty polyhydric alcohols may include Preferably, the polyalkylene oxide is most often polyethylene oxide, or polypropylene oxide or mixed polyethylene oxide/propylene oxide. Generally, the solubilizer contains 3 to 100, especially 5 to 80 alkylene oxide units. Fatty acids or fatty alcohols usually contain 8 to 24, especially 12 to 24, carbon atoms and are often linear. Solubilizers having an HLB value within the range of 12-20 used in the present invention include polyethylene glycol ethers of fatty alcohols, polyethylene glycol ethers of hydrogenated castor oil, polyethylene glycol derivatives of sorbitan esters, polysorbates, glycerol esters, It may be selected from the group consisting of polyethylene glycol derivatives of glycerol esters, alkyl phosphates, alkyl sulfates, and the like. Further examples of useful nonionic emulsifiers are listed in the CTFA Cosmetic Ingredient Handbook, 2nd Edition, 1990.
ある実施形態では、本発明で使用するのに適した可溶化剤の例として、限定するものではないが、PEG-40ヒマシ油、PEG-40水添ヒマシ油(BASF製のEumulgin(登録商標)CO 40)、PEG-60ヒマシ油、PEG-60水添ヒマシ油(BASF製のEumulgin(登録商標)CO 60)、セテアレス-2~18、セテス-2~16、イソセテス-2~30、ラウレス-2~16、ノノキシノール-2~18、オレス-5~20、ジラウリン酸PEG-20、ラウリン酸PEG-20グリセリル、ラウリン酸PEG-75ソルビタン、ポリソルベート-20~80、ステアレス-5~20、PPG-1-PEG-9ラウリルグリコールエーテル(Eumulgin(登録商標)L)が挙げられる。 In certain embodiments, examples of solubilizers suitable for use in the present invention include, but are not limited to, PEG-40 castor oil, PEG-40 hydrogenated castor oil (Eumulgin® from BASF). CO 40), PEG-60 castor oil, PEG-60 hydrogenated castor oil (Eumulgin® CO 60 from BASF), ceteareth-2-18, ceteth-2-16, isoceteth-2-30, laureth- 2-16, nonoxynol-2-18, oleth-5-20, PEG-20 dilaurate, PEG-20 glyceryl laurate, PEG-75 sorbitan laurate, polysorbate-20-80, steareth-5-20, PPG- 1-PEG-9 lauryl glycol ether (Eumulgin® L).
ある実施形態では、化粧品組成物の総重量に基づいて、可溶化剤は、0.01wt%~0.9wt%、好ましくは0.05wt%~0.8wt%、より好ましくは0.1wt%~0.5wt%の量で存在し得る。 In one embodiment, the solubilizer is present in an amount of 0.01 wt% to 0.9 wt%, preferably 0.05 wt% to 0.8 wt%, more preferably 0.1 wt% to 0.5 wt%, based on the total weight of the cosmetic composition. can exist in
ある実施形態では、非イオン性乳化剤(b)は、可溶化剤(c)と異なっていてもよい。 In some embodiments, the nonionic emulsifier (b) may be different than the solubilizer (c).
好ましい実施形態では、本発明による化粧品組成物であって、
それぞれ化粧品組成物の総重量に基づいて、
(a) 0.01wt%~2.0wt%のゲル形成(メタ)アクリルポリマー、
(b) 脂肪酸のポリエチレングリコールジエステル、脂肪酸のポリプロピレングリコールジエステル、及び脂肪酸のポリ(エチレン-co-プロピレングリコール)ジエステルからなる群から選択される、0.01wt%~1.0wt%(1.0wt%を除く)の少なくとも1種の非イオン性乳化剤、
(c) 0.01wt%~1.0wt%の、12~20の範囲内のHLB値を有する少なくとも1種の可溶化剤、
(d) 水、並びに
(e) 0~50wt%の少なくとも1種の皮膚軟化剤
を含み、
前記組成物が、ゲル又は水中油型エマルションの形態であり、好ましくはゲルの形態である、
化粧品組成物。
In a preferred embodiment, the cosmetic composition according to the invention comprises
Based on the total weight of the cosmetic composition, respectively,
(a) 0.01 wt% to 2.0 wt% of a gel-forming (meth)acrylic polymer;
(b) 0.01 wt% to 1.0 wt% (excluding 1.0 wt%) selected from the group consisting of polyethylene glycol diesters of fatty acids, polypropylene glycol diesters of fatty acids, and poly(ethylene-co-propylene glycol) diesters of fatty acids; at least one nonionic emulsifier of
(c) from 0.01 wt% to 1.0 wt% of at least one solubilizer with an HLB value in the range of 12 to 20;
(d) water;
(e) 0-50 wt% of at least one emollient,
said composition is in the form of a gel or an oil-in-water emulsion, preferably in the form of a gel;
cosmetic composition.
ある実施形態では、適切な皮膚軟化剤は、動物又は植物由来の油、鉱油、合成グリセリド、脂肪酸エステル、脂肪アルコール、脂肪アルコールエーテル、シリコーン油、及び脂肪族炭化水素からなる群から選択されてもよい。これらの材料は、揮発性であっても、又は不揮発性であってもよい。揮発性油は、不揮発性油及び/又は本記載において言及される他のワックスと組み合わせて使用されてもよい。適切な油は、脂肪族炭化水素、植物油、脂肪アルコール、脂肪アルコールのエステル、及び/又は動物若しくは植物油以外の脂肪酸、並びに合成グリセリド、或いはそれらの混合物から選択されてもよい。特に適した油は、植物油、シリコーン油、脂肪アルコールのエステル、及びそれらの混合物からなる群から選択されてもよい。 In some embodiments, suitable emollients may be selected from the group consisting of animal or vegetable derived oils, mineral oils, synthetic glycerides, fatty acid esters, fatty alcohols, fatty alcohol ethers, silicone oils, and aliphatic hydrocarbons. good. These materials may be volatile or non-volatile. Volatile oils may be used in combination with non-volatile oils and/or other waxes mentioned in this description. Suitable oils may be selected from aliphatic hydrocarbons, vegetable oils, fatty alcohols, esters of fatty alcohols, and/or fatty acids other than animal or vegetable oils, and synthetic glycerides, or mixtures thereof. Particularly suitable oils may be selected from the group consisting of vegetable oils, silicone oils, esters of fatty alcohols, and mixtures thereof.
本発明の化粧品組成物での使用に適した植物油は、アマニ油、ツバキ油、ヒマワリ油、アンズ油、ヘーゼルナッツ油、植物性スクアラン油、サザンカ油、ブドウ種子油、ピーナッツ油、ヤシ油、パーム核油、ダイズ油、マカダミアナッツ油、アボカド油、紅花油、スイートアーモンド油、アンズ油、トウモロコシ油、ホホバ油、オリーブ油、ゴマ油、パーム油、ユーカリ油、ローズマリー油、ラベンダー油、パイン油、タイム油、ミント油、カルダモン油、オレンジ花油、ヌカ油、コメ油、ナタネ油、ヒマシ油、及びそれらの混合物を非限定的に含んでもよい。 Vegetable oils suitable for use in the cosmetic compositions of the present invention include linseed oil, camellia oil, sunflower oil, apricot oil, hazelnut oil, vegetable squalane oil, sasanqua oil, grape seed oil, peanut oil, coconut oil, palm kernel oil. Oil, soybean oil, macadamia nut oil, avocado oil, safflower oil, sweet almond oil, apricot oil, corn oil, jojoba oil, olive oil, sesame oil, palm oil, eucalyptus oil, rosemary oil, lavender oil, pine oil, thyme oil , mint oil, cardamom oil, orange blossom oil, bran oil, rice oil, rapeseed oil, castor oil, and mixtures thereof.
本発明の化粧品組成物での使用に適した動物油は、スクアレン、ペルヒドロスクアレン、スクアラン、及びそれらの混合物を非限定的に含んでもよい。 Animal oils suitable for use in the cosmetic compositions of the present invention may include, without limitation, squalene, perhydrosqualene, squalane, and mixtures thereof.
本発明に使用するためのシリコーン油は、揮発性及び/又は不揮発性シリコン油のいずれかであってもよい。好ましいシリコーン油は、それらのINCI名でジメチコン及びジメチコノールとして知られる不揮発性シリコン油である。揮発性シリコーン油、例えばシクロメチコンは、不揮発性シリコーン並びに/又は本記載において言及される他のワックス及び/若しくは油と組み合わせて使用されてもよい。シリコーン油の例として、例えば、直鎖状オルガノポリシロキサン、例えば、ジメチルポリシロキサン(diemethylpolysiloxane)、メチルフェニルポリシロキサン、メチルハイドロジェンポリシロキサンなど;環状オルガノポリシロキサン、例えば、シクロペンタシロキサン、シクロヘキシルシロキサン、オクタメチルシクロテトラシロキサン、デカメチルシクロペンタシロキサン、ドデカメチルシクロヘキサシロキサン、及びそれらの混合物を挙げることができる。さらに、少なくとも1つのアリール基をその分子内に含むアリール化シリコーン、例えば、フェニルメチコン(phenyl methiocone)、フェニルトリメチコン、ジフェニルジメチコン、ジフェニルシロキシフェニルトリメチコン、テトラメチルテトラフェニルトリシロキサン(trisiloxiane)、トリフェニルトリメチコン、テトラメチルテトラフェニルトリシロキサン、及びトリメチルペンタフェニルトリシロキサンが、本発明の組成物に含まれてもよい。 Silicone oils for use in the present invention may be either volatile and/or non-volatile silicone oils. Preferred silicone oils are the non-volatile silicone oils known by their INCI names dimethicone and dimethiconol. Volatile silicone oils such as cyclomethicone may be used in combination with non-volatile silicones and/or other waxes and/or oils mentioned in this description. Examples of silicone oils include linear organopolysiloxanes such as diemethylpolysiloxane, methylphenylpolysiloxane, methylhydrogenpolysiloxane, etc.; cyclic organopolysiloxanes such as cyclopentasiloxane, cyclohexylsiloxane, Octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, and mixtures thereof may be mentioned. In addition, arylated silicones containing at least one aryl group in their molecule, such as phenyl methiocone, phenyl trimethicone, diphenyl dimethicone, diphenylsiloxyphenyl trimethicone, tetramethyltetraphenyltrisiloxane (trisiloxiane), Phenyltrimethicone, tetramethyltetraphenyltrisiloxane, and trimethylpentaphenyltrisiloxane may be included in the compositions of the present invention.
一部の実施形態では、適切な皮膚軟化剤は、6~22個、好ましくは8~18個の炭素原子を有する脂肪アルコールに基づくゲルべアルコール(例えば、BASF製のEutanol(登録商標)G)、直鎖状C6~C22脂肪酸と直鎖状又は分枝状C6~C22脂肪アルコールとのエステル、及び分枝状C6~C13カルボン酸と直鎖状又は分枝状C6~C22脂肪アルコールとのエステル、例えば、ミリスチン酸ミリスチル、パルミチン酸ミリスチル、ステアリン酸ミリスチル、イソステアリン酸ミリスチル、オレイン酸ミリスチル、ベヘン酸ミリスチル、エルカ酸ミリスチル、ミリスチン酸セチル、パルミチン酸セチル、ステアリン酸セチル、イソステアリン酸セチル、オレイン酸セチル、ベヘン酸セチル、エルカ酸セチル、ミリスチン酸ステアリル、パルミチン酸ステアリル、ステアリン酸ステアリル、イソステアリン酸ステアリル、オレイン酸ステアリル、ベヘン酸ステアリル、エルカ酸ステアリル、ミリスチン酸イソステアリル、パルミチン酸イソステアリル、ステアリン酸イソステアリル、イソステアリン酸イソステアリル、オレイン酸イソステアリル、ベヘン酸イソステアリル、オレイン酸イソステアリル、ミリスチン酸オレイル、パルミチン酸オレイル、ステアリン酸オレイル、イソステアリン酸オレイル、オレイン酸オレイル、ベヘン酸オレイル、エルカ酸オレイル、ミリスチン酸ベヘニル、パルミチン酸ベヘニル、ステアリン酸ベヘニル、イソステアリン酸ベヘニル、オレイン酸ベヘニル、ベヘン酸ベヘニル、エルカ酸ベヘニル、ミリスチン酸エルシル、パルミチン酸エルシル、ステアリン酸エルシル、イソステアリン酸エルシル、オレイン酸エルシル、ベヘン酸エルシル、及びエルカ酸エルシル;C3~C38アルキルヒドロキシカルボン酸と直鎖状又は分枝状C6~C22脂肪アルコールとのエステル、例えば、リンゴ酸ジエチルヘキシル;並びに直鎖状又は分枝状脂肪酸と多価アルコールとのエステル、例えば、プロピレングリコール、ジプロピレングリコール、又はトリプロピレングリコールを含んでもよい。また適切な合成グリセリドは、C6~C18脂肪酸に基づく液体モノ、ジ、及びトリグリセリドブレンド;例えば、C6~C10脂肪酸に基づくトリグリセリド(BASF製のMyritol(登録商標)312);C6~C22脂肪アルコール又はゲルべアルコールと芳香族カルボン酸、例えば安息香酸、とのエステル;C2~C12ジカルボン酸と1~22個の炭素原子を有する直鎖状若しくは分枝状アルコール又は2~10個の炭素原子及び2~6個のヒドロキシル基を有するポリオールとのエステル;植物油;分枝状第一級アルコール;直鎖状及び分枝状C6~C22脂肪アルコールカーボネート、例えば、炭酸ジカプリリル(Cetiol CC);6~18個を有する脂肪アルコールに基づくゲルベカーボネート;安息香酸と直鎖状又は分枝状のC6~C22アルコールとのエステル;直鎖状又は分枝状の、対称又は非対称の、アルキル基当たり6~22個の炭素原子を有するジアルキルエーテル、例えば、ジカプリリルエーテル(Cetiol OE);並びに脂肪族炭化水素、例えば、鉱油、ワセリン、石油ゼリー、スクアラン、スクアレン、又はジアルキルシクロヘキサンである。 In some embodiments, suitable emollients are Guerbet alcohols based on fatty alcohols having 6-22, preferably 8-18 carbon atoms (eg Eutanol® G from BASF). , esters of linear C 6 -C 22 fatty acids with linear or branched C 6 -C 22 fatty alcohols, and branched C 6 -C 13 carboxylic acids with linear or branched C 6 Esters with ~ C22 fatty alcohols, e.g. myristyl myristate, myristyl palmitate, myristyl stearate, myristyl isostearate, myristyl oleate, myristyl behenate, myristyl erucate, cetyl myristate, cetyl palmitate, cetyl stearate , cetyl isostearate, cetyl oleate, cetyl behenate, cetyl erucate, stearyl myristate, stearyl palmitate, stearyl stearate, stearyl isostearate, stearyl oleate, stearyl behenate, stearyl erucate, isostearyl myristate, isostearyl palmitate, isostearyl stearate, isostearyl isostearate, isostearyl oleate, isostearyl behenate, isostearyl oleate, oleyl myristate, oleyl palmitate, oleyl stearate, oleyl isostearate, oleyl oleate, Oleyl behenate, oleyl erucate, behenyl myristate, behenyl palmitate, behenyl stearate, behenyl isostearate, behenyl oleate, behenyl behenate, behenyl erucate, erucyl myristate, erucyl palmitate, erucyl stearate, isostearic acid erucyl, erucyl oleate, erucyl behenate, and erucyl erucate ; esters of C3- C38 alkyl hydroxycarboxylic acids with linear or branched C6 - C22 fatty alcohols, such as diethylhexyl malate; It may also include esters of linear or branched fatty acids with polyhydric alcohols, such as propylene glycol, dipropylene glycol, or tripropylene glycol. Suitable synthetic glycerides are also liquid mono-, di-, and triglyceride blends based on C6 - C18 fatty acids ; esters of C 22 fatty alcohols or Guerbet alcohols with aromatic carboxylic acids, such as benzoic acid; C 2 -C 12 dicarboxylic acids with linear or branched alcohols having 1 to 22 carbon atoms or 2 to 2 Esters with polyols having 10 carbon atoms and 2 to 6 hydroxyl groups; vegetable oils; branched primary alcohols; linear and branched C6- C22 fatty alcohol carbonates, such as dicaprylyl carbonate. ( Cetiol CC); Guerbet carbonates based on fatty alcohols with 6 to 18; esters of benzoic acid with linear or branched C6-C22 alcohols; linear or branched, symmetrical or unsymmetrical dialkyl ethers having 6 to 22 carbon atoms per alkyl group, such as dicaprylyl ether (Cetiol OE); and aliphatic hydrocarbons, such as mineral oil, petrolatum, petroleum jelly, squalane, squalene, or dialkylcyclohexanes. is.
一部の実施形態では、適切な皮膚軟化剤は化粧品として許容されるワックスも含んでもよく、当業者であれば、この用語が意味するものを容易に特定するであろう。例には、カルナウバ、オゾケライト、トリベヘン酸グリセリル、蜜ロウ、カンデリラ、パラフィン、ベーベリロウ、ラノリン、マイクロクリスタリンワックス、モンタン、ライスワックス、C12~C36脂肪酸の固体モノ、ジ、又はトリグリセロールエステル、ポリエチレン、ポリエチレン/ポリ酢酸ビニルコポリマー、ポリエチレン/ポリアクリル酸コポリマー、C12~C36脂肪アルコール、及びC12~C36脂肪アルコールと酸との固体エステルがあるが、本発明で使用されるワックスは、室温(25℃)で固体であることを条件とする。 In some embodiments, suitable emollients may also include cosmetically acceptable waxes, and those skilled in the art will readily identify what is meant by this term. Examples include carnauba, ozokerite, glyceryl tribehenate , beeswax, candelilla, paraffin, bayberry wax, lanolin, microcrystalline wax, montan, rice wax, solid mono-, di- or triglycerol esters of C12- C36 fatty acids, polyethylene. , polyethylene/polyvinyl acetate copolymers, polyethylene/polyacrylic acid copolymers, C 12 -C 36 fatty alcohols, and solid esters of C 12 -C 36 fatty alcohols and acids, the waxes used in the present invention are Provided that it is a solid at room temperature (25°C).
ある実施形態では、化粧品組成物の総重量に基づいて、皮膚軟化剤は、好ましくは0~40wt%、より好ましくは0~30wt%、最も好ましくは0~20wt%、例えば、0.01wt%~20wt%、0.1wt%~18wt%、1wt%~16wt%、3wt%~14wt%、5wt%~12wt%、7wt%~12wt%、8wt%~12wt%の量で存在し得る。 In one embodiment, based on the total weight of the cosmetic composition, the emollient is preferably 0-40 wt%, more preferably 0-30 wt%, most preferably 0-20 wt%, such as 0.01 wt%-20 wt%. %, 0.1 wt% to 18 wt%, 1 wt% to 16 wt%, 3 wt% to 14 wt%, 5 wt% to 12 wt%, 7 wt% to 12 wt%, 8 wt% to 12 wt%.
好ましい実施形態では、本発明による化粧品組成物であって、
それぞれ化粧品組成物の総重量に基づいて、
(a) 0.01wt%~2.0wt%のゲル形成(メタ)アクリルポリマー、
(b) 脂肪酸のポリエチレングリコールジエステル、脂肪酸のポリプロピレングリコールジエステル、及び脂肪酸のポリ(エチレン-co-プロピレングリコール)ジエステルからなる群から選択される、0.01wt%~1.0wt%(1.0wt%を除く)の少なくとも1種の非イオン性乳化剤、
(c) 0.01wt%~1.0wt%の、12~20の範囲内のHLB値を有する少なくとも1種の可溶化剤、
(d) 水、
(e) 0~50wt%の少なくとも1種の皮膚軟化剤、
(f) 0~10wt%の少なくとも1種の共乳化剤
を含み、
前記組成物が、ゲル又は水中油型エマルションの形態であり、好ましくはゲルの形態である、
化粧品組成物。
In a preferred embodiment, the cosmetic composition according to the invention comprises
Based on the total weight of the cosmetic composition, respectively,
(a) 0.01 wt% to 2.0 wt% of a gel-forming (meth)acrylic polymer;
(b) 0.01 wt% to 1.0 wt% (excluding 1.0 wt%) selected from the group consisting of polyethylene glycol diesters of fatty acids, polypropylene glycol diesters of fatty acids, and poly(ethylene-co-propylene glycol) diesters of fatty acids; at least one nonionic emulsifier of
(c) from 0.01 wt% to 1.0 wt% of at least one solubilizer with an HLB value in the range of 12 to 20;
(d) water;
(e) 0-50 wt% of at least one emollient,
(f) 0-10 wt% of at least one co-emulsifier,
said composition is in the form of a gel or an oil-in-water emulsion, preferably in the form of a gel;
cosmetic composition.
ある実施形態では、本発明の化粧品組成物は、組成物の粘度を改変してゲル又は水中油型エマルションの組織を形成することができる少なくとも1種の共乳化剤をさらに含む。本発明に適したものとして、限定するものではないが、8~22個、好ましくは12~18個の炭素原子を有する脂肪アルコール又はヒドロキシ脂肪アルコール、及びまた部分グリセリド、8~22個の炭素原子を有する脂肪酸又はヒドロキシ脂肪酸が挙げられる。例えば、適切な脂肪アルコールは、カプリルアルコール、デシルアルコール、ドデシルアルコール、テトラデシルアルコール、ヘキサデシルアルコール、セテアリルアルコール、ステアリルアルコール、エイコサノール、及びベヘニルアルコールからなる群から、好ましくは、テトラデシルアルコール、ヘキサデシルアルコール、セテアリルアルコール、及びステアリルアルコールからなる群から選択されてもよい。特に、共乳化剤はセテアリルアルコール(BASF製のLanette(登録商標)O)である。 In certain embodiments, the cosmetic composition of the present invention further comprises at least one co-emulsifier capable of modifying the viscosity of the composition to form a gel or oil-in-water emulsion structure. Fatty alcohols or hydroxyfatty alcohols having 8 to 22, preferably 12 to 18 carbon atoms, and also partial glycerides, 8 to 22 carbon atoms, are suitable for the present invention, but are not limited thereto. and fatty acids or hydroxy fatty acids having For example, suitable fatty alcohols are from the group consisting of capryl alcohol, decyl alcohol, dodecyl alcohol, tetradecyl alcohol, hexadecyl alcohol, cetearyl alcohol, stearyl alcohol, eicosanol and behenyl alcohol, preferably tetradecyl alcohol, hexadecyl It may be selected from the group consisting of alcohol, cetearyl alcohol, and stearyl alcohol. In particular, the co-emulsifier is cetearyl alcohol (Lanette® O from BASF).
ある実施形態では、化粧品組成物の総重量に基づいて、共乳化剤は、0.01wt%~10wt%、0.05wt%~9wt%、0.1wt%~8wt%、0.2wt%~7wt%、0.4wt%~6wt%、0.6wt%~5wt%、0.8wt%~4wt%、1.0wt%~3wt%、1.2wt%~2wt%、好ましくは1.0wt%~3wt%、より好ましくは1.2wt%~2wt%の量で存在し得る。 In some embodiments, based on the total weight of the cosmetic composition, the co-emulsifier is 0.01 wt% to 10 wt%, 0.05 wt% to 9 wt%, 0.1 wt% to 8 wt%, 0.2 wt% to 7 wt%, 0.4 wt%. ~6 wt%, 0.6 wt% to 5 wt%, 0.8 wt% to 4 wt%, 1.0 wt% to 3 wt%, 1.2 wt% to 2 wt%, preferably 1.0 wt% to 3 wt%, more preferably 1.2 wt% to 2 wt% can be present in an amount of
ある実施形態では、化粧品組成物の総重量に基づいて、非イオン性乳化剤(b)と12~20の範囲内のHLB値を有する可溶化剤(c)との重量比は、1:10~10:1、好ましくは1:7~7:1、より好ましくは1:5~5:1、最も好ましくは1:3~3:1、とりわけ好ましくは1:2~2:1の範囲内であり得る。特に好ましくは、前記重量比は1:1であり得る。特に、皮膚軟化剤が存在し、組成物がゲルの形態である実施形態では、化粧品組成物の総重量に基づいて、非イオン性乳化剤(b)と12~20の範囲内のHLB値を有する可溶化剤(c)との重量比は、1:10~5:1、好ましくは1:7~5:1、より好ましくは1:5~5:1、最も好ましくは1:3~3:1、とりわけ好ましくは1:2~2:1の範囲内であり得る。特に好ましくは、前記重量比は1:1であり得る。 In one embodiment, the weight ratio of the nonionic emulsifier (b) to the solubilizer (c) having an HLB value within the range of 12-20, based on the total weight of the cosmetic composition, is from 1:10 to within the range of 10:1, preferably 1:7 to 7:1, more preferably 1:5 to 5:1, most preferably 1:3 to 3:1, most preferably 1:2 to 2:1 could be. Particularly preferably, said weight ratio may be 1:1. In particular, in embodiments where an emollient is present and the composition is in the form of a gel, the nonionic emulsifier (b) has an HLB value within the range of 12 to 20, based on the total weight of the cosmetic composition. The weight ratio with the solubilizer (c) is 1:10 to 5:1, preferably 1:7 to 5:1, more preferably 1:5 to 5:1, most preferably 1:3 to 3:1. 1, particularly preferably within the range of 1:2 to 2:1. Particularly preferably, said weight ratio may be 1:1.
ある実施形態では、ゲルの形態の本発明の化粧品組成物は、2,000~200,000cps、好ましくは4,000~180,000cps、より好ましくは6,000~160,000cps、最も好ましくは8,000~140,000cpsの範囲内の粘度を有し得る。ある実施形態では、水中油型エマルションの形態の本発明の化粧品組成物は、2,000~500,000cps、好ましくは4,000~450,000cps、より好ましくは6,000~400,000cps、最も好ましくは8,000~350,000cps、特に好ましくは10,000~300,000cps、とりわけ好ましくは12,000~250,000の範囲内の粘度を有し得る。粘度は、Brookfield RV粘度計で、Zahn粘度カップ#6を使用して室温で測定することができる。 In one embodiment, the cosmetic composition of the present invention in gel form has a viscosity within the range of 2,000-200,000 cps, preferably 4,000-180,000 cps, more preferably 6,000-160,000 cps, most preferably 8,000-140,000 cps. can have In one embodiment, the cosmetic composition of the present invention in the form of an oil-in-water emulsion has a concentration of 2,000 to 500,000 cps, preferably 4,000 to 450,000 cps, more preferably 6,000 to 400,000 cps, most preferably 8,000 to 350,000 cps, particularly preferably may have a viscosity in the range from 10,000 to 300,000 cps, particularly preferably from 12,000 to 250,000. Viscosity can be measured at room temperature on a Brookfield RV viscometer using a Zahn viscosity cup #6.
本発明の実施形態のいずれか一つによれば、本発明の化粧品組成物は、水、例えば、精製水、脱イオン水、又はフローラルウォーター、及び場合により1種以上の水混和性溶媒を含む。本発明の実施形態のいずれか一つによれば、水相は、任意の化粧品として許容される水性材料、例えば、脱イオン水、精製水、又はフローラルウォーターであり得る。 According to any one of the embodiments of the present invention, the cosmetic composition of the present invention comprises water, such as purified water, deionized water or floral water, and optionally one or more water-miscible solvents. . According to any one of the embodiments of the present invention, the aqueous phase can be any cosmetically acceptable aqueous material such as deionized water, purified water, or floral water.
ある実施形態では、化粧品組成物の総重量に基づいて、水は、20wt%~99wt%、又は25wt%~95wt%、又は30wt%~90wt%、好ましくは40wt%~85wt%、より好ましくは50wt%~80wt%の量で存在し得る。 In some embodiments, based on the total weight of the cosmetic composition, the water is 20 wt% to 99 wt%, or 25 wt% to 95 wt%, or 30 wt% to 90 wt%, preferably 40 wt% to 85 wt%, more preferably 50 wt%. % to 80 wt%.
本発明の化粧品組成物は、後述するような追加の助剤をさらに含んでもよく、それは0wt%~10wt%、好ましくは0.01wt%~8wt%、より好ましくは0.01wt%~6wt%、最も好ましくは0.01wt%~5wt%の量で存在し得る。 The cosmetic composition of the present invention may further comprise additional adjuvants as described below, which are from 0 wt% to 10 wt%, preferably from 0.01 wt% to 8 wt%, more preferably from 0.01 wt% to 6 wt%, most preferably may be present in an amount from 0.01 wt% to 5 wt%.
本発明の実施形態のいずれか一つによれば、本発明の化粧品組成物は、化粧品組成物に汎用される界面活性剤を含めた追加の界面活性剤をさらに含んでもよく、その非限定的な例として、非イオン性乳化剤、例えば、糖エステル及びポリエステル、アルコキシル化糖エステル及びポリエステル、C1~C30脂肪アルコールのC1~C30脂肪酸エステル、C1~C30脂肪アルコールのアルコキシル化誘導体、ポリエトキシル化C1~C30脂肪アルコール、例えば、BASFからEumulgin(登録商標)BA 25の商品名で販売されているエトキシル化ベヘニルアルコール、C1~C30脂肪酸のポリグリセリルエステル、ポリオールのC1~C30エステル、ポリオールのC1~C30エーテルが挙げられる。一部の実施形態では、追加の非イオン性乳化剤は、組成物の総重量で0~10wt%、又は1wt%~8wt%、又は2wt%~7wt%の量で存在する。 According to any one of the embodiments of the present invention, the cosmetic composition of the present invention may further comprise additional surfactants, including surfactants commonly used in cosmetic compositions, including but not limited to Examples include nonionic emulsifiers such as sugar esters and polyesters, alkoxylated sugar esters and polyesters, C 1 -C 30 fatty acid esters of C 1 -C 30 fatty alcohols, alkoxylated derivatives of C 1 -C 30 fatty alcohols. , polyethoxylated C 1 -C 30 fatty alcohols, for example ethoxylated behenyl alcohols sold by BASF under the trade name Eumulgin® BA 25, polyglyceryl esters of C 1 -C 30 fatty acids, C 1 -C 30 polyols. C 30 esters, C 1 -C 30 ethers of polyols. In some embodiments, the additional nonionic emulsifier is present in an amount of 0-10 wt%, or 1 wt%-8 wt%, or 2 wt%-7 wt% of the total weight of the composition.
本発明の化粧品組成物は、アニオン性乳化剤、例えば、リン酸アルキル、ポリオキシアルキレン脂肪酸エステルホスフェート、脂肪酸アミド、アシルラクチレート、アニオン性スルフェート、アニオン性スルホネート、アニオン性サルコシネート、イセチオネート、タウレート、ラクチレート、グルタメート、アルキルサクシネート、及びスルホサクシネート、並びにそれらの混合物をさらに含んでもよい。 The cosmetic composition of the present invention contains anionic emulsifiers such as alkyl phosphates, polyoxyalkylene fatty acid ester phosphates, fatty acid amides, acyl lactylates, anionic sulfates, anionic sulfonates, anionic sarcosinates, isethionates, taurates, lactylates, Glutamate, alkylsuccinates, and sulfosuccinates, and mixtures thereof may also be included.
本発明の化粧品組成物は、両性乳化剤をさらに含んでもよい。双性イオン性界面活性剤の非限定的な例は、ベタイン、スルタイン、ヒドロキシスルタイン、アルキルイミノアセテート、イミノジアルカノエート、アミノアルカノエート、及びそれらの混合物からなる群から選択されるものである。 The cosmetic composition of the present invention may further comprise an amphoteric emulsifier. Non-limiting examples of zwitterionic surfactants are those selected from the group consisting of betaines, sultaines, hydroxysultaines, alkyliminoacetates, iminodialkanoates, aminoalkanoates, and mixtures thereof. .
本発明の化粧品組成物は、上述の成分の他に、化粧品組成物に一般にブレンドされる添加剤、例えば、保湿剤、抗シワ剤/老化防止剤、細胞賦活薬、抗炎症剤、酸化防止剤、UV吸収/散乱剤、防腐剤、pH調整剤、着色剤、香味料、パール剤(pearlizer)、カプセル剤などを、本発明の化粧品組成物の特性が損なわれない限り含んでもよい。 In addition to the above ingredients, the cosmetic composition of the present invention contains additives commonly blended in cosmetic compositions, such as moisturizing agents, anti-wrinkle agents/anti-aging agents, cell activators, anti-inflammatory agents, and antioxidants. , UV absorbing/scattering agents, preservatives, pH adjusters, coloring agents, flavoring agents, pearlizers, capsules, etc. may be included as long as the properties of the cosmetic composition of the present invention are not impaired.
本発明の化粧品組成物での使用に適した保湿剤は、多価アルコール、例えば、グリセロール、1,3-ブチレングリコール、1,2-プロパンジオール、1,3-プロパンジオール、ペンタンジオール、ヘキサンジオール、ヘプタンジオール、デカンジオール、ソルビトールなど;ムコ多糖、例えば、ヒアルロン酸ナトリウム、コンドロイチン硫酸など;アミノ酸、例えば、アラニン、ピロリドンカルボン酸ナトリウムなど、又はそれらの塩を非限定的に含んでもよい。一部の実施形態では、保湿剤は、組成物の総重量で0~10wt%、又は1wt%~9wt%、又は2wt%~8wt%、又は3wt%~7wt%の量で存在する。 Humectants suitable for use in the cosmetic composition of the present invention include polyhydric alcohols such as glycerol, 1,3-butylene glycol, 1,2-propanediol, 1,3-propanediol, pentanediol, hexanediol. , heptanediol, decanediol, sorbitol and the like; mucopolysaccharides such as sodium hyaluronate, chondroitin sulfate and the like; amino acids such as alanine, sodium pyrrolidone carboxylate and the like, or salts thereof, without limitation. In some embodiments, the humectant is present in an amount of 0 to 10 wt%, or 1 wt% to 9 wt%, or 2 wt% to 8 wt%, or 3 wt% to 7 wt% of the total weight of the composition.
本発明の化粧品組成物での使用に適した抗シワ剤/老化防止剤は、加水分解卵殻膜、アテロコラーゲン、コメヌカエキス、ルイボスエキスなどを非限定的に含んでもよい。 Anti-wrinkle/anti-aging agents suitable for use in the cosmetic compositions of the present invention may include, without limitation, hydrolyzed eggshell membrane, atelocollagen, rice bran extract, rooibos extract, and the like.
本発明の化粧品組成物での使用に適した細胞賦活剤は、デオキシリボ核酸のナトリウム塩、酵母エキス、オタネニンジンエキスなどを非限定的に含んでもよい。 Suitable cell activators for use in the cosmetic composition of the present invention may include, without limitation, sodium salts of deoxyribonucleic acids, yeast extract, Panax ginseng extract, and the like.
本発明の化粧品組成物での使用に適した抗炎症剤は、アラントイン、アロエベラエキス、キダチアロエエキス、カモミールエキス、カンゾウエキス、グリチルリチン酸二カリウムなどを非限定的に含んでもよい。 Anti-inflammatory agents suitable for use in the cosmetic compositions of the present invention may include, without limitation, allantoin, aloe vera extract, aloe vera extract, chamomile extract, licorice extract, dipotassium glycyrrhizinate, and the like.
本発明の化粧品組成物での使用に適した酸化防止剤は、ビタミンE、例えば、酢酸トコフェロール、d-δ-トコフェロール、dl-α-トコフェロール、天然ビタミンEなど;ポリフェノール、例えば、グルコシルルチン、タンニン酸など;没食子酸類、例えば、没食子酸、没食子酸プロピルなど及びそれらの誘導体;植物エキス、例えば、シソ葉エキス、セージ葉エキスなどを非限定的に含んでもよい。 Antioxidants suitable for use in the cosmetic compositions of the present invention include vitamin E, such as tocopherol acetate, d-delta-tocopherol, dl-alpha-tocopherol, natural vitamin E; polyphenols, such as glucosylrutin, tannins; acids and the like; gallic acids such as gallic acid, propyl gallate and derivatives thereof; plant extracts such as perilla leaf extract, sage leaf extract and the like, without limitation.
本発明の化粧品組成物での使用に適したUV吸収/散乱剤は、メチレンビスベンゾトリアゾリルテトラメチルブチルフェノール、ビスエチルヘキシルオキシフェノールメトキシフェニルトリアジン、ジエチルアミノヒドロキシベンゾイル安息香酸ヘキシル、パラジメチルアミノベンゾエート2-エチルヘキシル、オキシベンゾン-3-(2-ヒドロキシ-4-メトキシベンゾフェノン)、パラメトキシ桂皮酸2-エチルヘキシル、4-tert-ブチル-4’-メトキシジベンゾイルメタン、酸化チタンなどを非限定的に含んでもよい。 Suitable UV absorbing/scattering agents for use in the cosmetic compositions of the present invention include methylenebisbenzotriazolyltetramethylbutylphenol, bisethylhexyloxyphenol methoxyphenyltriazine, diethylaminohydroxybenzoylhexylbenzoate, paradimethylaminobenzoate 2- Non-limiting examples may include ethylhexyl, oxybenzone-3-(2-hydroxy-4-methoxybenzophenone), 2-ethylhexyl paramethoxycinnamate, 4-tert-butyl-4'-methoxydibenzoylmethane, titanium oxide, and the like.
本発明の化粧品組成物での使用に適した防腐剤は、安息香酸ナトリウム、フェノキシエタノール、パラオキシベンゾエート、例えば、p-ヒドロキシ安息香酸メチル、パラヒドロキシ安息香酸エチル、p-オキシ安息香酸プロピルなどを非限定的に含んでもよい。 Preservatives suitable for use in the cosmetic compositions of the present invention include, but are not limited to, sodium benzoate, phenoxyethanol, paraoxybenzoates such as methyl p-hydroxybenzoate, ethyl parahydroxybenzoate, propyl p-hydroxybenzoate, and the like. may optionally include
本発明の化粧品組成物での使用に適したpH調整剤は、無機酸及び有機酸、並びに無機塩基及び有機塩基、特に、アンモニア水、コハク酸、クエン酸、クエン酸ナトリウム、酒石酸、酒石酸ナトリウム(sodium tartarate)、水酸化ナトリウム、水酸化カリウム、トリエタノールアミン、グルコノラクトンを非限定的に含んでもよく、好ましくは、pH調整剤は、アミノメチルプロパノール、トリエタノールアミン、L-アルギニン、トリメタミン、PEG-15コカミン、ジイソプロパノールアミン、トリイソプロパノールアミン、又はテトラヒドロキシプロピルエチレンジアミンである。 Suitable pH adjusters for use in the cosmetic composition of the present invention include inorganic and organic acids and inorganic and organic bases, especially aqueous ammonia, succinic acid, citric acid, sodium citrate, tartaric acid, sodium tartrate ( sodium tartrate), sodium hydroxide, potassium hydroxide, triethanolamine, gluconolactone, preferably the pH adjuster is aminomethylpropanol, triethanolamine, L-arginine, trimethamine, PEG-15 cocamine, diisopropanolamine, triisopropanolamine, or tetrahydroxypropylethylenediamine.
本発明の化粧品組成物での使用に適した着色剤は、無機顔料、例えば、紺青、群青、赤色酸化鉄、黒色酸化鉄、鉄黄、タルク、カオリン、マンガンバイオレット、カーボンブラックなど;天然染料、例えば、β-カロチン、リコペン、シソ色素、サフロールイエロー、シコニン、クロロフィルなど、タール色素、例えば、赤色102号、赤色201号、青色202号など、レーキ顔料、例えば、赤色3号アルミニウムレーキ、黄色4号アルミニウムレーキ、青色1号バリウムレーキなどを非限定的に含んでもよい。 Colorants suitable for use in the cosmetic composition of the present invention include inorganic pigments such as Prussian blue, ultramarine blue, red iron oxide, black iron oxide, iron yellow, talc, kaolin, manganese violet, carbon black, etc.; natural dyes, For example, β-carotene, lycopene, perilla pigment, safrole yellow, shikonin, chlorophyll, etc., tar pigments, such as Red No. 102, Red No. 201, Blue No. 202, etc., lake pigments, such as Red No. 3 aluminum lake, yellow 4 No. 1 aluminum lake, blue no. 1 barium lake, and the like, without limitation.
本発明の化粧品組成物での使用に適した香味料は、天然香味料、例えば、シナモン油、ラベンダー油、ジャスミン油、ハッカ油、オレンジ油、ローズ油など;合成香味料、例えば、シトロネロール、オイゲノール、ゲラニオール、メントールなどを非限定的に含んでもよい。 Flavoring agents suitable for use in the cosmetic composition of the present invention include natural flavoring agents such as cinnamon oil, lavender oil, jasmine oil, peppermint oil, orange oil, rose oil, etc.; synthetic flavoring agents such as citronellol, eugenol. , geraniol, menthol, and the like, without limitation.
本発明の組成物は、他の添加剤、例えば、限定するものではないが、研磨剤、吸収剤、起泡剤(foam building agent)、消泡剤、抗菌剤(例えば、ヨードプロピルブチルカルバメート)、生物学的添加剤、増量剤、キレート剤、皮膜形成剤又は材料、例えば、組成物の皮膜形成特性を助けるためのポリマー(例えば、エイコセンとビニルピロリドンとのコポリマー)、噴射剤、還元剤、皮膚脱色及び美白剤(例えば、ヒドロキノン、コウジ酸、アスコルビン酸、リン酸アスコルビルマグネシウム、アスコルビルグルコサミン)、皮膚鎮静剤及び/又は治癒剤(例えば、パンテノール及び誘導体(例えば、エチルパンテノール)、アロエベラ、パントテン酸及びその誘導体、アラントイン、ビサボロール、シリコーン、並びに脂肪アルコールも含んでもよい。 The compositions of the present invention may also contain other additives such as, but not limited to, abrasives, absorbents, foam building agents, defoamers, antimicrobial agents (e.g., iodopropyl butyl carbamate). , biological additives, extenders, chelating agents, film-forming agents or materials such as polymers (e.g., copolymers of eicosene and vinylpyrrolidone) to aid the film-forming properties of the composition, propellants, reducing agents, skin bleaching and lightening agents (e.g. hydroquinone, kojic acid, ascorbic acid, magnesium ascorbyl phosphate, ascorbyl glucosamine), skin soothing and/or healing agents (e.g. panthenol and derivatives (e.g. ethylpanthenol), aloe vera, Pantothenic acid and its derivatives, allantoin, bisabolol, silicones, and fatty alcohols may also be included.
1種類以上の上述の添加剤は、本発明の化粧品組成物に、本発明の化粧品組成物の特性が損なわれない限り、化粧品組成物に一般に使用される量で存在し得る。 One or more of the above-mentioned additives can be present in the cosmetic composition of the present invention in amounts commonly used in cosmetic compositions as long as the properties of the cosmetic composition of the present invention are not impaired.
第2の態様では、本発明は、パーソナルケア製品を調製するための化粧品組成物の使用を提供する。 In a second aspect, the invention provides the use of the cosmetic composition for preparing personal care products.
ある実施形態では、パーソナルケア製品は、以下のうちの一つであり得る:スキンケア製品、ベビーケア製品、ボディケア製品、ヘアケア製品、クレンジング製品、メイクアップリムーバー、マッサージ製品、浴用製品、シェービング製品、化粧品、練り歯磨き、脱臭剤、制汗剤、昆虫忌避剤、シャンプー、ヘアコンディショナー、サンケア製品、シャワーゲル、ヘアスタイリングゲル、毛髪フケ防止剤製品、育毛促進剤製品、毛髪着色剤製品、毛髪脱色剤製品、毛髪縮れ防止剤製品、縮毛矯正剤製品、潤滑ゲル製品、及び殺精子ゲル製品。 In some embodiments, the personal care product can be one of the following: skin care products, baby care products, body care products, hair care products, cleansing products, makeup removers, massage products, bath products, shaving products, Cosmetics, Toothpastes, Deodorants, Antiperspirants, Insect Repellents, Shampoos, Hair Conditioners, Sun Care Products, Shower Gels, Hair Styling Gels, Hair Antidandruff Products, Hair Growth Promoter Products, Hair Colorants Products, Hair Bleaching Agents products, anti-frizz products, straightener products, lubricating gel products, and spermicidal gel products.
本発明の目的のために、「パーソナルケア」という用語は、例えば、メイクアップリムーバー、ボディウォッシュ及びクレンザー、並びに皮膚へのリーブオン塗布を含めた、皮膚へ塗布するための化粧品及びスキンケア組成物を指すことが意図される。本発明において、「パーソナルケア」という用語はまた、例えば、シャンプー、リーブオンコンディショナー、リンスオフコンディショナー、スタイリングゲル、ポマード、ヘアカラー製品(例えば、二剤式染毛剤)、ヘアスプレー、及びムースを含めたヘアケア組成物を指すことが意図される。好ましくは、パーソナルケア組成物は、化粧品として許容される。「化粧品として許容される」とは、パーソナルケア組成物に典型的に見出される量で存在する場合に有毒である材料が本開示の一部として企図されていないことを明らかに示すことを意図するものである。 For the purposes of the present invention, the term "personal care" refers to cosmetic and skin care compositions intended for application to the skin, including, for example, make-up removers, body washes and cleansers, and leave-on applications to the skin. is intended. In the present invention, the term "personal care" also includes, for example, shampoos, leave-on conditioners, rinse-off conditioners, styling gels, pomades, hair coloring products (e.g., two-part hair dyes), hair sprays, and mousses. It is intended to refer to hair care compositions containing Preferably, the personal care composition is cosmetically acceptable. "Cosmetically acceptable" is intended to clearly indicate that materials that are toxic when present in amounts typically found in personal care compositions are not contemplated as part of this disclosure. It is.
該組成物、並びに本発明の化粧品組成物を含有する製剤及び製品は、当業者に周知される方法論を使用して調製されてもよい。 The compositions, as well as formulations and products containing the cosmetic compositions of the present invention, may be prepared using methodologies well known to those skilled in the art.
第3の態様では、本発明は、皮膚の少なくとも1つの部分上に塗布された場合の官能特性を改善する方法、例えば、広がりの改善、水様の感触の改善、ワックス様の感触の低減、べとつきの低減のための方法を提供する。 In a third aspect, the present invention provides a method of improving sensory properties when applied on at least one portion of the skin, e.g., improved spreading, improved watery feel, reduced waxy feel, Provide a method for reducing stickiness.
本発明の態様は、以降の具体例から明らかとなろう。具体例は、本発明の好ましい実施形態を示すものであるが、例示のみを目的とすることを意図しており、本発明の範囲を限定することを意図するものではないことが理解されるべきである。 Aspects of the invention will become apparent from the following specific examples. It should be understood that the specific examples, while indicating preferred embodiments of the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention. is.
[実施例]
本発明を以下の実施例によって詳細に説明する。
[Example]
The invention is illustrated in detail by the following examples.
1. 調製例
以下の原料を使用した。
Myritol(登録商標)312 トリ(カプリル酸/カプリン酸)グリセリル
Lanette(登録商標)O セテアリルアルコール
Eumulgin(登録商標)BA 25 べヘネス-25
1,3-BG ブチレングリコール
Eumulgin(登録商標)EO 33 ジステアリン酸PEG-150
Eumulgin(登録商標)CO 40 PEG-40水添ヒマシ油
Tinovis(登録商標)GTC-UP (アクリレーツ/メタクリル酸ベヘネス-25)コポリマー
活性成分(以降「a.i.」と呼ぶ)の含有量:約30%
Cosmedia(登録商標)Ace ポリアクリル酸ナトリウム、炭酸ジカプリリル、カプリン酸ポリグリセリル-3
活性成分の含有量:約50%
Luvigel(登録商標)EM トリ(カプリル酸/カプリン酸)グリセリル及びアクリレーツコポリマーナトリウム
活性成分の含有量:約25%
Cosmedia(登録商標) SP ポリアクリル酸ナトリウム
活性成分の含有量:>88%
Neutrol TE テトラヒドロキシプロピルエチレンジアミン
Phenonip XB フェノキシエタノール(及び)メチルパラベン(及び)エチルパラベン(及び)プロピルパラベン
1. Preparation Example The following raw materials were used.
Myritol® 312 Caprylic/Capric Triglyceryl
Lanette® O cetearyl alcohol
Eumulgin® BA 25 Beheneth-25
1,3-BG butylene glycol
Eumulgin® EO 33 PEG-150 Distearate
Eumulgin® CO 40 PEG-40 hydrogenated castor oil
Content of Tinovis® GTC-UP (acrylates/beheneth-25 methacrylate) copolymer active ingredient (hereinafter referred to as “ai”): about 30%
Cosmedia® Ace Sodium Polyacrylate, Dicaprylyl Carbonate, Polyglyceryl-3 Caprate
Active ingredient content: about 50%
Luvigel® EM tri(caprylic/capric) glyceryl and acrylates copolymer sodium active ingredient content: about 25%
Cosmedia® SP Sodium Polyacrylate Active Ingredient Content: >88%
Neutrol TE Tetrahydroxypropylethylenediamine
Phenonip XB Phenoxyethanol (and) Methylparaben (and) Ethylparaben (and) Propylparaben
上の原料はBASF SEから入手可能である。 The above raw materials are available from BASF SE.
表1及び2に組成を示す化粧品組成物は、以下のように調製した。 The cosmetic compositions whose compositions are shown in Tables 1 and 2 were prepared as follows.
200mlのビーカーに、皮膚軟化剤、共乳化剤及び非イオン性乳化剤及び追加の乳化剤を添加して油相(ブレンド1)を形成し、次いでそれを500rpmで撹拌しながら80℃に加熱した。別の300mlのビーカーに、水、可溶化剤、保湿剤を添加して水相(ブレンド2)を形成し、次いでそれを1,500rpmで撹拌しながら80℃に加熱した。続いて、ゲル形成(メタ)アクリルポリマーを水/油相(水相中にはTinovis GTC UP、もう一方の油相中にはCosmedia ACE、Cosmedia SP、及びLuvigel EM)中に1,500rpmで3分間撹拌しながら均一になるまで分散させた。次いで、油相を水相中に5,000rpmで8分間撹拌しながら添加して均一な混合物を得、これを室温まで冷却した。最後に、pH調整剤及び防腐剤を混合物に添加した。 In a 200 ml beaker, emollients, co-emulsifiers and non-ionic emulsifiers and additional emulsifiers were added to form the oil phase (Blend 1), which was then heated to 80°C with stirring at 500 rpm. In another 300 ml beaker, water, solubilizer, humectant were added to form the aqueous phase (Blend 2), which was then heated to 80° C. with stirring at 1,500 rpm. Subsequently, the gel-forming (meth)acrylic polymer was placed in the water/oil phase (Tinovis GTC UP in the water phase and Cosmedia ACE, Cosmedia SP, and Luvigel EM in the other oil phase) at 1,500 rpm for 3 minutes. Disperse with stirring until uniform. The oil phase was then added into the water phase with stirring at 5,000 rpm for 8 minutes to obtain a homogeneous mixture, which was cooled to room temperature. Finally, pH modifiers and preservatives were added to the mixture.
表1~2の組成は、組成物の総重量に基づくものである。 The compositions in Tables 1-2 are based on the total weight of the composition.
調製中に、比較例1~7におけるLanette(登録商標)O、又はTinovis(登録商標)GTC-UP、Cosmedia(登録商標)Ace、若しくはLuvigel(登録商標)EMのうちの1つの量は、ゲル組織の官能性を得るためには実施例1~4のものと比較して表1に示す値まで増加させなければならないことが見出された。それらが表1に示す値より少ないと、ゲルの形態を得ることができなかった。 During preparation, an amount of Lanette® O, or one of Tinovis® GTC-UP, Cosmedia® Ace, or Luvigel® EM in Comparative Examples 1-7 was added to the gel. It was found that the tissue functionality had to be increased compared to that of Examples 1-4 to the values shown in Table 1 in order to obtain it. If they were less than the values shown in Table 1, no gel morphology could be obtained.
2. 使用例
試験を開始する前に、ボランティアに、周囲条件及び/又は気分に応じて5~10分与えて慣れさせた。試験は、DIN規格DIN Norm 10962に準拠して調製した室内で、およそ50%の相対湿度及びおよそ23℃の温度で実施した。毒物学的クリアランスの後、ボランティア(すべて中国人女性)は前腕上で試料を試験し、「-1、-0.5、0、0.5、又は1」の点数を付けた。
2. Use Cases Prior to the start of the study, volunteers were allowed 5-10 minutes to habituate, depending on ambient conditions and/or mood. The tests were carried out in a room prepared according to DIN standard DIN Norm 10962 at a relative humidity of approximately 50% and a temperature of approximately 23°C. After toxicological clearance, volunteers (all Chinese women) tested samples on their forearms and scored "-1, -0.5, 0, 0.5, or 1."
1) 広がり
ゲルの形態の150μLの試料を前腕の内側に塗布した。人差し指及び中指の指先で20回円形に動かして、塗布した試料を広げた。この動作の間に、前腕上でどの製品が動きに対して試料の抵抗をより少なく生じたかについて、ボランティアに評価するように求めた。抵抗が少ないほど、容易に広がることを意味する。
1) Spreading 150 μL of sample in gel form was applied to the inside of the forearm. The applied sample was spread using 20 circular motions between the fingertips of the index and middle fingers. During this movement, volunteers were asked to rate which product on the forearm produced less resistance of the sample to movement. Less resistance means easier spreading.
点数「-1」は、参考例と比較して相当広がりにくいことを意味する。
点数「-0.5」は、参考例と比較して広がりにくいことを意味する。
点数「0」は、参考例と比較して同等に広がることを意味する。
点数「0.5」は、参考例と比較して広がりやすいことを意味する。
点数「1」は、参考例と比較して相当広がりやすいことを意味する。
A score of "-1" means that it is considerably difficult to spread compared to the reference example.
A score of "-0.5" means that it is difficult to spread compared to the reference example.
A score of "0" means equally spread compared to the reference example.
A score of "0.5" means that it spreads more easily than the reference example.
A score of "1" means that it is considerably easier to spread compared to the reference example.
2) 使用時の水様性
円形に広げる最初の10回の間に、前腕上でどの製品がより多くの水を含有していたかについて、ボランティアに評価するように求めた。水が多いほど、使用時に水様の感触が大きいことを意味する。
2) Wateriness in Use Volunteers were asked to rate which product contained more water on the forearm during the first 10 circular spreads. More water means more watery feel in use.
点数「-1」は、参考例と比較して使用時に水様性が相当少ないことを意味する。
点数「-0.5」は、参考例と比較して使用時に水様性が少ないことを意味する。
点数「0」は、参考例と比較して使用時に水様性が同等であることを意味する。
点数「0.5」は、参考例と比較して使用時に水様性が多いことを意味する。
点数「1」は、参考例と比較して使用時に水様性が相当多いことを意味する。
A score of "-1" means that the wateriness in use is considerably less than that of the reference example.
A score of "-0.5" means less wateriness during use compared to the reference example.
A score of "0" means equivalent wateriness in use compared to the reference example.
A score of "0.5" means that there is more wateriness during use compared to the reference example.
A score of "1" means that there is considerably more wateriness during use than in the Reference Example.
3) 使用時のべとつき
円形に広げる最初の10回の間に、前腕上でどの製品がより重い油性の感触を生じたかについて、ボランティアに評価するように求めた。油性の感触が重いほど、使用時にべとつきが大きいことを意味する。
3) Stickiness in Use Volunteers were asked to rate which product produced a heavier, oilier feel on the forearm during the first 10 circular spreads. A heavier oily feel means more stickiness in use.
点数「-1」は、参考例と比較して使用時にべとつきが相当多いことを意味する。
点数「-0.5」は、参考例と比較して使用時にべとつきが多いことを意味する。
点数「0」は、参考例と比較して使用時にべとつきが同等であることを意味する。
点数「0.5」は、参考例と比較して使用時にべとつきが少ないことを意味する。
点数「1」は、参考例と比較して使用時にべとつきが相当少ないことを意味する。
A score of "-1" means that there is considerably more stickiness during use than in the reference example.
A score of "-0.5" means that there is much stickiness during use compared to the reference example.
A score of "0" means equivalent stickiness during use compared to the reference example.
A score of "0.5" means less stickiness during use compared to the reference example.
A score of "1" means that there is considerably less stickiness during use compared to the reference example.
4) ワックス様の感触
150μLの試料を、完全に吸収されるまで広げた。続いてボランティアは、前腕に残るワックス様の感触を感じるために人差し指及び中指で処置した場所を強く押し、両方の指を上側から下に動かした。抵抗が大きいほど、ワックス様の感触が大きいことを意味する。
4) Wax-like feel
150 μL of sample was spread until completely absorbed. Volunteers then pressed hard on the treated site with their index and middle fingers to feel a wax-like sensation that remained on their forearms, moving both fingers from top to bottom. Higher resistance means more wax-like feel.
点数「-1」は、参考例と比較してワックス様の感触が相当多いことを意味する。
点数「-0.5」は、参考例と比較してワックス様の感触が多いことを意味する。
点数「0」は、参考例と比較してワックス様の感触が同等であることを意味する。
点数「0.5」は、参考例と比較してワックス様の感触が少ないことを意味する。
点数「1」は、参考例と比較してワックス様の感触が相当少ないことを意味する。
A score of "-1" means that the wax-like feeling is considerably greater than that of the reference example.
A score of "-0.5" means that there is more wax-like feeling compared to the reference example.
A score of "0" means that the wax-like feeling is equivalent to that of the Reference Example.
A score of "0.5" means less wax-like feeling compared to the reference example.
A score of "1" means that the wax-like feeling is considerably less than that of the reference example.
評価結果を表3~4に示した。 Evaluation results are shown in Tables 3 and 4.
3. 結果分析 3. Result analysis
表3及び4は、本発明の実施例及び比較例からの結果を示している。 Tables 3 and 4 show the results from the inventive examples and comparative examples.
表3からわかるように、実施例1と比較例1及び6、実施例2と比較例2及び4、実施例3と比較例3及び5、実施例4と比較例7との比較によって、Eumulgin EO 33をEumulgin CO 40と組み合わせると、化粧品組成物中のLanette O又はゲル形成(メタ)アクリルポリマーの量が低減する。加えて、容易に広がる、使用時により水様になる、使用時にべとつきが少なくなる、及び/又はワックス様の感触が少なくなるという点で、実施例1~4が比較例1~7より良好であることが表3から明らかである。 As can be seen from Table 3, by comparing Example 1 with Comparative Examples 1 and 6, Example 2 with Comparative Examples 2 and 4, Example 3 with Comparative Examples 3 and 5, and Example 4 with Comparative Example 7, Eumulgin Combining EO 33 with Eumulgin CO 40 reduces the amount of Lanette O or gel-forming (meth)acrylic polymer in the cosmetic composition. In addition, Examples 1-4 are better than Comparative Examples 1-7 in that they spread easily, are more watery in use, are less sticky in use, and/or have a less waxy feel. It is clear from Table 3 that there is
表4は、幾つかの実施例及び比較例の評価結果を示している。Eumulgin EO 33及びEumulgin CO 40の量を少なくすると、得られた組成物の効力が、容易に広がる、使用時により水様になる、使用時にべとつきが少なくなる、及び/又はワックス様の感触が少なくなるという点で良好になることがわかる。 Table 4 shows evaluation results of some examples and comparative examples. With lower amounts of Eumulgin EO 33 and Eumulgin CO 40, the efficacy of the resulting composition is easier to spread, more watery in use, less sticky in use, and/or less waxy in feel. It can be seen that it will be good in terms of becoming.
Claims (20)
それぞれ化粧品組成物の総重量に基づいて、
(a) 0.01wt%~2.0wt%の少なくとも1種のゲル形成(メタ)アクリルポリマー、
(b) 脂肪酸のポリエチレングリコールジエステル、脂肪酸のポリプロピレングリコールジエステル、及び脂肪酸のポリ(エチレン-co-プロピレングリコール)ジエステルからなる群から選択される、0.01wt%~1.0wt%(1.0wt%を除く)の少なくとも1種の非イオン性乳化剤、
(c) 0.01wt%~1.0wt%の、12~20の範囲内のHLB値を有する少なくとも1種の可溶化剤、並びに
(d) 水、
を含み、
前記組成物が、ゲル又は水中油型エマルションの形態であり、好ましくはゲルの形態である、
化粧品組成物。 A cosmetic composition,
Based on the total weight of the cosmetic composition, respectively,
(a) 0.01 wt% to 2.0 wt% of at least one gel-forming (meth)acrylic polymer;
(b) 0.01 wt% to 1.0 wt% (excluding 1.0 wt%) selected from the group consisting of polyethylene glycol diesters of fatty acids, polypropylene glycol diesters of fatty acids, and poly(ethylene-co-propylene glycol) diesters of fatty acids; at least one nonionic emulsifier of
(c) from 0.01 wt% to 1.0 wt% of at least one solubilizer with an HLB value within the range of 12 to 20, and
(d) water;
including
said composition is in the form of a gel or an oil-in-water emulsion, preferably in the form of a gel;
cosmetic composition.
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DE10307410A1 (en) * | 2003-02-20 | 2004-09-02 | Cognis Deutschland Gmbh & Co. Kg | Emulsifier composition and transparent or translucent microemulsions containing it |
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