JP2023502442A - 凝集体を含む液体を移送する装置、システム、および方法 - Google Patents
凝集体を含む液体を移送する装置、システム、および方法 Download PDFInfo
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- 239000007788 liquid Substances 0.000 title claims abstract description 78
- 238000000034 method Methods 0.000 title claims abstract description 18
- 239000006249 magnetic particle Substances 0.000 claims abstract description 88
- 239000002245 particle Substances 0.000 claims abstract description 52
- 239000000696 magnetic material Substances 0.000 claims description 5
- 238000003018 immunoassay Methods 0.000 claims description 3
- 238000005054 agglomeration Methods 0.000 abstract description 2
- 230000002776 aggregation Effects 0.000 abstract description 2
- 238000012546 transfer Methods 0.000 description 11
- 239000000463 material Substances 0.000 description 8
- 238000010586 diagram Methods 0.000 description 7
- 230000005291 magnetic effect Effects 0.000 description 7
- 239000002699 waste material Substances 0.000 description 6
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- 102000004169 proteins and genes Human genes 0.000 description 2
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- 238000000429 assembly Methods 0.000 description 1
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- 229910052710 silicon Inorganic materials 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00564—Handling or washing solid phase elements, e.g. beads
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Abstract
Description
本出願は、2019年11月22日に出願された「APPARATUS, SYSTEMS, AND METHODS OF TRANSFERRING LIQUIDS CONTAINING AGGREGATES」という名称の米国仮特許出願第62/939,494号の利益を主張し、その開示全体を、あらゆる目的で参照によって本明細書に組み入れる。
Claims (22)
- 液体中の粒子を受け入れるように構成された装置であって:
ハウジング入口およびハウジング出口を含むハウジングと;
ハウジング入口とハウジング出口との間でハウジング内に位置する、粒子の最大横方向寸法よりも大きい空間を有するメッシュと
を含む前記装置。 - 空間は方形である、請求項1に記載の装置。
- 空間は1.3mm未満の幅を有する、請求項1に記載の装置。
- 空間は1.15mm~1.25mmの範囲内の幅を有する、請求項1に記載の装置。
- ハウジングは非磁性材料で作られる、請求項1に記載の装置。
- 入口弁を有するポンプに連結されるように構成され、入口弁は、横方向入口寸法を有し、空間は、入口弁の横方向入口寸法よりも小さい、請求項1に記載の装置。
- メッシュは非磁性材料で作られる、請求項1に記載の装置。
- 粒子は磁性粒子である、請求項1に記載の装置。
- メッシュは、空間の間に位置する部材を含み、該部材は、0.127mm~0.381mmの範囲内の厚さを有する、請求項1に記載の装置。
- メッシュは31%~41%の範囲内の開口面積を有する、請求項1に記載の装置。
- 第1の方向に延びる第1のワイヤおよび第2の方向に延びる第2のワイヤを含み、ここで、第1のワイヤは第2のワイヤと一体に織り合わされ、空間は、第1のワイヤと第2のワイヤとの間に位置する、請求項1に記載の装置。
- 臨床診断分析器であって:
粒子を含む液体を圧送するように構成されたポンプと;
粒子の凝集体を分離するように構成されたメッシュ装置とを含み、該メッシュ装置は:
ポンプに連結されたハウジング入口およびハウジング出口を含むハウジングと;
ハウジング入口とハウジング出口との間でハウジング内に位置する、粒子の最大横方向寸法よりも大きい空間を有するメッシュと
を含む、前記臨床診断分析器。 - イムノアッセイ機器に実装される、請求項12に記載の臨床診断分析器。
- 粒子は磁性粒子である、請求項12に記載の臨床診断分析器。
- 空間は1.15mm~1.25mmの範囲内の幅を有する、請求項12に記載の臨床診断分析器。
- 空間は1.3mm未満の幅を有する、請求項12に記載の臨床診断分析器。
- 空間は1.15mm~1.25mmの範囲内の幅を有する、請求項12に記載の臨床診断分析器。
- メッシュは、第1の方向に延びる第1のワイヤおよび第2の方向に延びる第2のワイヤを含み、第1のワイヤは第2のワイヤと一体に織り合わされ、空間は、第1のワイヤと第2のワイヤとの間に位置する、請求項12に記載の臨床診断分析器。
- メッシュは、空間の間に位置する1つまたはそれ以上の部材を含み、該部材は、0.127mm~0.381mmの範囲内の厚さを有する、請求項12に記載の臨床診断分析器。
- メッシュは31%~41%の範囲内の開口面積を有する、請求項12に記載の臨床診断分析器。
- 粒子を含む液体を移送する方法であって:
粒子の最大横方向寸法よりも大きい幅を有する空間を有するメッシュを提供する工程と;
粒子を含む液体をメッシュを通して動かす工程とを含み、該動きにより、粒子の凝集体を分離させる、
前記方法。 - 粒子は磁性粒子である、請求項21に記載の方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962939494P | 2019-11-22 | 2019-11-22 | |
US62/939,494 | 2019-11-22 | ||
PCT/US2020/061123 WO2021102048A1 (en) | 2019-11-22 | 2020-11-18 | Apparatus, systems, and methods of transferring liquids containing aggregates |
Publications (2)
Publication Number | Publication Date |
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JP2023502442A true JP2023502442A (ja) | 2023-01-24 |
JP7462043B2 JP7462043B2 (ja) | 2024-04-04 |
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JP2022529466A Active JP7462043B2 (ja) | 2019-11-22 | 2020-11-18 | 凝集体を含む液体を移送する装置、システム、および方法 |
Country Status (5)
Country | Link |
---|---|
US (1) | US20230020665A1 (ja) |
EP (1) | EP4061531A4 (ja) |
JP (1) | JP7462043B2 (ja) |
CN (1) | CN114667188B (ja) |
WO (1) | WO2021102048A1 (ja) |
Citations (6)
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EP0670185A2 (en) * | 1994-01-24 | 1995-09-06 | LANSDORP, Peter, M. | Device for separating magnetically labelled cells |
US20130072400A1 (en) * | 2010-05-13 | 2013-03-21 | Consejo Superior De Investigaciones Cientificas | Method for the diagnosis/prognosis of colorectal cancer |
JP2015078932A (ja) * | 2013-10-17 | 2015-04-23 | 株式会社フジクラ | イムノアッセイ用デバイス |
WO2015103642A1 (en) * | 2014-01-06 | 2015-07-09 | Blue Gas Marine, Inc. | Gaseous fuel conversion system for marine vessels, and related accessories |
US20170072128A1 (en) * | 2015-09-14 | 2017-03-16 | Medisieve Ltd | Magnetic filter apparatus and method |
JP2017070316A (ja) * | 2017-01-31 | 2017-04-13 | ヤマハ発動機株式会社 | 対象物の移動装置 |
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US20030161816A1 (en) * | 2001-12-07 | 2003-08-28 | Fraser John K. | Systems and methods for treating patients with processed lipoaspirate cells |
US8264674B2 (en) | 2004-04-23 | 2012-09-11 | The Furukawa Electric Co., Ltd. | Methods of separating, identifying and dispensing specimen and device therefor, and analyzing device method |
WO2009044088A1 (en) * | 2007-10-02 | 2009-04-09 | Inverness Medical Switzerland Gmbh | Assay device and method |
US10240186B2 (en) * | 2011-07-14 | 2019-03-26 | Fluxion Biosciences, Inc. | Devices, systems, and methods for magnetic separation |
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JP6313977B2 (ja) * | 2011-12-28 | 2018-04-18 | 株式会社日立ハイテクノロジーズ | 試料分析装置及び試料分析方法 |
WO2016087397A1 (en) * | 2014-12-02 | 2016-06-09 | Koninklijke Philips N.V. | Dispersion and accumulation of magnetic particles in a microfluidic system |
DE102016217435B4 (de) * | 2016-09-13 | 2018-08-02 | Albert-Ludwigs-Universität Freiburg | Fluidpumpe und Verfahren zum Betreiben einer Fluidpumpe |
CN110192097B (zh) * | 2016-11-18 | 2023-02-07 | 美国西门子医学诊断股份有限公司 | 液体测定物的顺序多波长测量 |
WO2019191137A1 (en) * | 2018-03-26 | 2019-10-03 | Levitas, Inc. | Magnetic particle isolation device and methods of use |
CN209565224U (zh) * | 2019-01-08 | 2019-11-01 | 河南科技学院 | 一种磁性催化剂筛选装置 |
-
2020
- 2020-11-18 JP JP2022529466A patent/JP7462043B2/ja active Active
- 2020-11-18 EP EP20890352.6A patent/EP4061531A4/en active Pending
- 2020-11-18 US US17/756,254 patent/US20230020665A1/en active Pending
- 2020-11-18 WO PCT/US2020/061123 patent/WO2021102048A1/en unknown
- 2020-11-18 CN CN202080080458.6A patent/CN114667188B/zh active Active
Patent Citations (6)
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EP0670185A2 (en) * | 1994-01-24 | 1995-09-06 | LANSDORP, Peter, M. | Device for separating magnetically labelled cells |
US20130072400A1 (en) * | 2010-05-13 | 2013-03-21 | Consejo Superior De Investigaciones Cientificas | Method for the diagnosis/prognosis of colorectal cancer |
JP2015078932A (ja) * | 2013-10-17 | 2015-04-23 | 株式会社フジクラ | イムノアッセイ用デバイス |
WO2015103642A1 (en) * | 2014-01-06 | 2015-07-09 | Blue Gas Marine, Inc. | Gaseous fuel conversion system for marine vessels, and related accessories |
US20170072128A1 (en) * | 2015-09-14 | 2017-03-16 | Medisieve Ltd | Magnetic filter apparatus and method |
JP2017070316A (ja) * | 2017-01-31 | 2017-04-13 | ヤマハ発動機株式会社 | 対象物の移動装置 |
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Title |
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Also Published As
Publication number | Publication date |
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CN114667188B (zh) | 2023-06-27 |
WO2021102048A1 (en) | 2021-05-27 |
US20230020665A1 (en) | 2023-01-19 |
JP7462043B2 (ja) | 2024-04-04 |
EP4061531A4 (en) | 2023-01-11 |
EP4061531A1 (en) | 2022-09-28 |
CN114667188A (zh) | 2022-06-24 |
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