JP2023174760A5 - - Google Patents

Download PDF

Info

Publication number
JP2023174760A5
JP2023174760A5 JP2023173584A JP2023173584A JP2023174760A5 JP 2023174760 A5 JP2023174760 A5 JP 2023174760A5 JP 2023173584 A JP2023173584 A JP 2023173584A JP 2023173584 A JP2023173584 A JP 2023173584A JP 2023174760 A5 JP2023174760 A5 JP 2023174760A5
Authority
JP
Japan
Prior art keywords
mlpscs
composition
cells
human
mlpsc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023173584A
Other languages
English (en)
Japanese (ja)
Other versions
JP7787130B2 (ja
JP2023174760A (ja
Filing date
Publication date
Priority claimed from PCT/EP2018/061503 external-priority patent/WO2018202853A1/en
Application filed filed Critical
Publication of JP2023174760A publication Critical patent/JP2023174760A/ja
Publication of JP2023174760A5 publication Critical patent/JP2023174760A5/ja
Priority to JP2025230822A priority Critical patent/JP2026034487A/ja
Application granted granted Critical
Publication of JP7787130B2 publication Critical patent/JP7787130B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023173584A 2017-05-04 2023-10-05 向上した免疫抑制作用を有する間葉系前駆または幹細胞 Active JP7787130B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025230822A JP2026034487A (ja) 2017-05-04 2025-12-04 向上した免疫抑制作用を有する間葉系前駆または幹細胞

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
AU2017901633 2017-05-04
AU2017901633A AU2017901633A0 (en) 2017-05-04 Potency assay for immunosuppression
AU2017901636A AU2017901636A0 (en) 2017-05-04 Method for treating Graft versus Host Disease (GVHD)
AU2017901636 2017-05-04
AU2018900551A AU2018900551A0 (en) 2018-02-21 Potency assay for immunosuppression II
AU2018900551 2018-02-21
PCT/EP2018/061503 WO2018202853A1 (en) 2017-05-04 2018-05-04 Mesenchymal lineage precursor or stem cells with enhanced immunosuppression
JP2019560259A JP7398959B2 (ja) 2017-05-04 2018-05-04 向上した免疫抑制作用を有する間葉系前駆または幹細胞

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2019560259A Division JP7398959B2 (ja) 2017-05-04 2018-05-04 向上した免疫抑制作用を有する間葉系前駆または幹細胞

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025230822A Division JP2026034487A (ja) 2017-05-04 2025-12-04 向上した免疫抑制作用を有する間葉系前駆または幹細胞

Publications (3)

Publication Number Publication Date
JP2023174760A JP2023174760A (ja) 2023-12-08
JP2023174760A5 true JP2023174760A5 (https=) 2024-07-05
JP7787130B2 JP7787130B2 (ja) 2025-12-16

Family

ID=62222586

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019560259A Active JP7398959B2 (ja) 2017-05-04 2018-05-04 向上した免疫抑制作用を有する間葉系前駆または幹細胞
JP2023173584A Active JP7787130B2 (ja) 2017-05-04 2023-10-05 向上した免疫抑制作用を有する間葉系前駆または幹細胞
JP2025230822A Pending JP2026034487A (ja) 2017-05-04 2025-12-04 向上した免疫抑制作用を有する間葉系前駆または幹細胞

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2019560259A Active JP7398959B2 (ja) 2017-05-04 2018-05-04 向上した免疫抑制作用を有する間葉系前駆または幹細胞

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025230822A Pending JP2026034487A (ja) 2017-05-04 2025-12-04 向上した免疫抑制作用を有する間葉系前駆または幹細胞

Country Status (10)

Country Link
US (1) US20200325450A1 (https=)
EP (2) EP4137562A1 (https=)
JP (3) JP7398959B2 (https=)
KR (2) KR102660506B1 (https=)
CN (1) CN110753751A (https=)
AU (2) AU2018262788B2 (https=)
BR (1) BR112019022901A2 (https=)
CA (1) CA3062112A1 (https=)
SG (1) SG11201909856XA (https=)
WO (1) WO2018202853A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120087868A1 (en) 2010-10-08 2012-04-12 Gabriele Todd Nanoparticle-loaded cells
SI2785359T1 (sl) 2011-11-30 2018-11-30 Astellas Institute For Regenerative Medicine Mezenhimske stromalne celice in uporabe povezane z njimi
US8961956B2 (en) 2011-11-30 2015-02-24 Ocata Therapeutics, Inc. Mesenchymal stromal cells and uses related thereto
HK1208054A1 (en) 2012-07-12 2016-02-19 爱姆斯坦生物技术公司 Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof
SG11201909856XA (en) * 2017-05-04 2019-11-28 Mesoblast Int Sarl Mesenchymal lineage precursor or stem cells with enhanced immunosuppression
SG11202004680UA (en) 2017-11-22 2020-06-29 Mesoblast Int Sarl Cellular compositions and methods of treatment i
KR20220143092A (ko) * 2020-02-19 2022-10-24 메조블라스트 인터내셔널 에스에이알엘 만성 이식편 대 숙주 질환의 치료 방법
JP7793284B2 (ja) * 2020-03-02 2026-01-05 株式会社ガイアバイオメディシン 高活性ｎｋ細胞の処理方法
JP2023530098A (ja) * 2020-06-11 2023-07-13 メゾブラスト・インターナショナル・エスアーエールエル 間葉系前駆細胞又は幹細胞の３ｄ培養
AU2021323475A1 (en) * 2020-08-10 2023-04-13 Mesoblast International Sarl A composition comprising mesenchymal precursor or stem cells and their use
CN112444479B (zh) * 2021-02-01 2021-05-07 宁波大学 基于并行处理技术的单细胞质谱分析系统及方法
CN113881707B (zh) * 2021-10-25 2023-07-14 中国人民解放军军事科学院军事医学研究院 调控脐带间充质干细胞免疫抑制作用的产品、方法及用途
US20250032552A1 (en) * 2021-12-23 2025-01-30 Mesoblast International Sárl Method of treating severe graft versus host disease
CA3260880A1 (en) * 2022-07-05 2024-01-11 Mesoblast International Sarl CRYOPROVERTED INTERMEDIATE AND BIOLOGICAL ACTIVITY TEST FOR IT
KR20250049337A (ko) 2022-08-09 2025-04-11 엑손모빌 케미칼 패턴츠 인코포레이티드 디페닐실란 가교 c1 대칭 촉매의 제조 방법 및 이로부터 제조된 중합체
WO2024168161A1 (en) * 2023-02-08 2024-08-15 Mesoblast International Sarl Potency assay and manufacturing method
WO2025196663A1 (en) * 2024-03-19 2025-09-25 Mesoblast International Sarl Potency assay and manufacturing method ii
CN118147232B (zh) * 2024-05-09 2024-07-19 中国人民解放军联勤保障部队第九二〇医院 一种过表达tps1间充质干细胞的构建方法及其应用

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4593089A (en) 1980-07-30 1986-06-03 Abbott Laboratories Fluorescent polarization immunoassay utilizing substituted triazinylaminofluorescein aminoglycosides
US4751190A (en) 1985-07-22 1988-06-14 Abbott Laboratories Fluorescence polarization immunoassay and reagents for use therein
US5139941A (en) 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
AU8200191A (en) 1990-07-09 1992-02-04 United States of America, as represented by the Secretary, U.S. Department of Commerce, The High efficiency packaging of mutant adeno-associated virus using amber suppressions
US5173414A (en) 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5837539A (en) 1990-11-16 1998-11-17 Osiris Therapeutics, Inc. Monoclonal antibodies for human mesenchymal stem cells
DE69233013T2 (de) 1991-08-20 2004-03-04 The Government Of The United States Of America As Represented By The Secretary Of National Institute Of Health, Office Of Technology Transfer Adenovirus vermittelter gentransfer in den gastrointestinaltrakt
DE4211351A1 (de) 1992-04-04 1993-10-07 Behringwerke Ag Verfahren zur Analyse partikelverstärkter Agglutinationsreaktionen auf Zentrifugalanalysatoren durch Bestimmung der Trübungsaufhellung
WO1994026877A1 (en) 1993-05-17 1994-11-24 The Regents Of The University Of California Ribozyme gene therapy for hiv infection and aids
US6541213B1 (en) 1996-03-29 2003-04-01 University Of Washington Microscale diffusion immunoassay
CA2244326C (en) 1997-08-11 2006-03-28 Shinichi Eda Microparticle enhanced light scattering agglutination assay and microparticle reagents therefor
US6566051B1 (en) 1999-01-15 2003-05-20 Medtox Scientific, Inc. Lateral flow test strip
AU2003901668A0 (en) 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
US7205159B2 (en) 2001-08-20 2007-04-17 Proteome Systems Intellectual Property Pty Ltd. Diagnostic testing process and apparatus
WO2004046729A2 (en) 2002-11-21 2004-06-03 The University Of Leicester Bodily fluid markers of tissue hypoxia
CN101248171B (zh) 2005-04-12 2015-11-25 迈索布拉斯特股份有限公司 通过组织非特异性碱性磷酸酶分离成人多潜能细胞
US20070258963A1 (en) 2006-01-13 2007-11-08 Osiris Therapeutics, Inc. Mesenchymal stem cells expressing TNF-alpha receptors
KR101891260B1 (ko) * 2010-07-02 2018-08-24 메소블라스트, 아이엔씨. T-세포 매개된 면역 질환의 치료
US20120087868A1 (en) * 2010-10-08 2012-04-12 Gabriele Todd Nanoparticle-loaded cells
KR20150016117A (ko) * 2013-07-30 2015-02-11 코아스템(주) 인간 골수 유래 중간엽 줄기세포를 유효성분으로 포함하는 자가면역질환의 예방 또는 치료용 약제학적 조성물
SG11201607925SA (en) * 2014-04-07 2016-10-28 Mesoblast Internat Sarl Improved stem cell composition
EP3236977B1 (en) * 2014-12-23 2023-06-21 Mesoblast International Sàrl Method for treating heart failure
SG11201909856XA (en) 2017-05-04 2019-11-28 Mesoblast Int Sarl Mesenchymal lineage precursor or stem cells with enhanced immunosuppression

Similar Documents

Publication Publication Date Title
JP2023174760A5 (https=)
Chang et al. Effects of mesenchymal stem cell‐derived paracrine signals and their delivery strategies
Li et al. Bioactive MXene promoting angiogenesis and skeletal muscle regeneration through regulating M2 polarization and oxidation stress
Martini et al. Aging induces cardiac mesenchymal stromal cell senescence and promotes endothelial cell fate of the CD90+ subset
Xie et al. Characterization of human ethmoid sinus mucosa derived mesenchymal stem cells (hESMSCs) and the application of hESMSCs cell sheets in bone regeneration
Son et al. Decellularized human periodontal ligament for periodontium regeneration
CN103881129B (zh) 一种聚醚醚酮材料及其表面改性的方法
Awais et al. Human dental pulp stem cells exhibit osteogenic differentiation potential
Green et al. Collagen Synthesis by Human Fibroblast Strains.
JP2018515211A5 (https=)
CN111979187A (zh) 一种抗人间充质干细胞衰老及增强其干性特征的方法
Pozio et al. Titanium nanotubes stimulate osteoblast differentiation of stem cells from pulp and adipose tissue
Kolliopoulos et al. Crosstalk between macrophages and mesenchymal stem cells shape patterns of osteogenesis and immunomodulation in mineralized collagen scaffolds
Zhou et al. The role of different macrophages-derived conditioned media in dental pulp tissue regeneration
Metzger et al. Interleukin-6 secretion in mice is associated with reduced glucose-6-phosphatase and liver glycogen levels
Li et al. Comparison of the therapeutic effects of mesenchymal stem cells derived from human dental pulp (DP), adipose tissue (AD), placental amniotic membrane (PM), and umbilical cord (UC) on postmenopausal osteoporosis
Wang et al. Prevention of Intrauterine Adhesion with Platelet‐Rich Plasma Double‐Network Hydrogel
Jiang et al. Decellularized extracellular matrix scaffold loaded with regulatory T cell-conditioned medium induces M2 macrophage polarization
Yin et al. Amniotic membrane mesenchymal stem cells‐based therapy improves Bmi‐1‐deficient mandible osteoporosis through stimulating osteoblastic bone formation and inhibiting osteoclastic bone resorption
Tang et al. Extracellular vesicles derived from Lipopolysaccharide-Pretreated periodontal ligament stem cells ameliorate inflammatory responses in experimental colitis via the PI3K/AKT signaling pathway
Nam et al. Differential gene expression profiles of human periodontal ligament cells preserved in Hank's balanced salt solution and milk
JP2023056591A5 (https=)
Simon et al. Type IV collagen production by rat pulmonary alveolar epithelial cells
CN117866853B (zh) 一株具有宫颈癌细胞促凋亡作用的乳酸片球菌及其应用
CN118717709A (zh) 一种具有口腔牙周炎症靶向和炎性中和功能的复合仿生纳米材料及其制备方法与应用