JP2023093527A5 - - Google Patents

Download PDF

Info

Publication number
JP2023093527A5
JP2023093527A5 JP2023060867A JP2023060867A JP2023093527A5 JP 2023093527 A5 JP2023093527 A5 JP 2023093527A5 JP 2023060867 A JP2023060867 A JP 2023060867A JP 2023060867 A JP2023060867 A JP 2023060867A JP 2023093527 A5 JP2023093527 A5 JP 2023093527A5
Authority
JP
Japan
Prior art keywords
fgfr2
days
once
leucovorin
oxaliplatin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023060867A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023093527A (ja
JP7573062B2 (ja
Filing date
Publication date
Priority claimed from JP2019562617A external-priority patent/JP7299842B2/ja
Application filed filed Critical
Publication of JP2023093527A publication Critical patent/JP2023093527A/ja
Publication of JP2023093527A5 publication Critical patent/JP2023093527A5/ja
Priority to JP2024177680A priority Critical patent/JP2025004195A/ja
Application granted granted Critical
Publication of JP7573062B2 publication Critical patent/JP7573062B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023060867A 2017-05-16 2023-04-04 がん治療における化学療法剤と組み合わせた抗fgfr2抗体 Active JP7573062B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024177680A JP2025004195A (ja) 2017-05-16 2024-10-10 がん治療における化学療法剤と組み合わせた抗fgfr2抗体

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762507053P 2017-05-16 2017-05-16
US62/507,053 2017-05-16
US201762581992P 2017-11-06 2017-11-06
US62/581,992 2017-11-06
JP2019562617A JP7299842B2 (ja) 2017-05-16 2018-05-15 がん治療における化学療法剤と組み合わせた抗fgfr2抗体

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2019562617A Division JP7299842B2 (ja) 2017-05-16 2018-05-15 がん治療における化学療法剤と組み合わせた抗fgfr2抗体

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024177680A Division JP2025004195A (ja) 2017-05-16 2024-10-10 がん治療における化学療法剤と組み合わせた抗fgfr2抗体

Publications (3)

Publication Number Publication Date
JP2023093527A JP2023093527A (ja) 2023-07-04
JP2023093527A5 true JP2023093527A5 (https=) 2024-01-04
JP7573062B2 JP7573062B2 (ja) 2024-10-24

Family

ID=62567776

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019562617A Active JP7299842B2 (ja) 2017-05-16 2018-05-15 がん治療における化学療法剤と組み合わせた抗fgfr2抗体
JP2023060867A Active JP7573062B2 (ja) 2017-05-16 2023-04-04 がん治療における化学療法剤と組み合わせた抗fgfr2抗体
JP2024177680A Pending JP2025004195A (ja) 2017-05-16 2024-10-10 がん治療における化学療法剤と組み合わせた抗fgfr2抗体

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2019562617A Active JP7299842B2 (ja) 2017-05-16 2018-05-15 がん治療における化学療法剤と組み合わせた抗fgfr2抗体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024177680A Pending JP2025004195A (ja) 2017-05-16 2024-10-10 がん治療における化学療法剤と組み合わせた抗fgfr2抗体

Country Status (23)

Country Link
US (3) US11091555B2 (https=)
EP (2) EP4650004A3 (https=)
JP (3) JP7299842B2 (https=)
KR (2) KR102749931B1 (https=)
CN (2) CN110621336B (https=)
AU (2) AU2018269984B2 (https=)
BR (1) BR112019023898A2 (https=)
CA (1) CA3062177A1 (https=)
DK (1) DK3624837T3 (https=)
ES (1) ES3041987T3 (https=)
FI (1) FI3624837T3 (https=)
HR (1) HRP20251144T1 (https=)
HU (1) HUE073202T2 (https=)
IL (1) IL270454B2 (https=)
LT (1) LT3624837T (https=)
MX (1) MX2024000614A (https=)
PL (1) PL3624837T3 (https=)
PT (1) PT3624837T (https=)
RS (1) RS67296B1 (https=)
SG (1) SG10202112636SA (https=)
SI (1) SI3624837T1 (https=)
SM (1) SMT202500362T1 (https=)
WO (1) WO2018213304A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102516152B1 (ko) 2013-08-01 2023-03-31 파이브 프라임 테라퓨틱스, 인크. 비푸코실화된 항-fgfr2iiib 항체
MX2018006181A (es) * 2015-11-23 2018-09-24 Five Prime Therapeutics Inc Inhibidores de fgfr2 solos o en combinacion con agentes que estimulan el sistema inmunitario en el tratamiento contra el cancer.
PT3624837T (pt) 2017-05-16 2025-10-01 Five Prime Therapeutics Inc Anticorpos anti-fgfr2 em combinação com agentes quimioterapêuticos no tratamento do cancro
KR20220119144A (ko) * 2019-12-24 2022-08-26 디잘 (지앙수) 파마슈티칼 씨오., 리미티드 신규한 항fgfr2b 항체
CN111760026B (zh) * 2020-08-06 2026-04-03 汪炬 FGFR2b抑制分子在制备治疗PAF介导的疾病药物中的应用
JP2024501565A (ja) * 2020-12-29 2024-01-12 深▲せん▼福沃薬業有限公司 抗fgfr2抗体およびその使用
TW202342527A (zh) * 2022-02-25 2023-11-01 美商安進公司 鱗狀非小細胞肺癌之治療
CN117917435A (zh) * 2022-10-21 2024-04-23 北京天广实生物技术股份有限公司 结合fgfr2b的抗体及其用途
KR20250126131A (ko) * 2022-12-28 2025-08-22 쑤저우 트랜스센타 테라퓨틱스 컴퍼니 리미티드 항-fgfr2b 항체 및 이의 용도
WO2025067442A1 (zh) * 2023-09-28 2025-04-03 南京维立志博生物科技股份有限公司 抗fgfr2抗体和包含其的多特异性结合分子
TW202540177A (zh) * 2023-11-14 2025-10-16 大陸商蘇州創勝醫藥集團有限公司 抗-FGFR2b免疫偶聯物及其於治療癌症的用途
WO2025130905A1 (zh) * 2023-12-18 2025-06-26 山东先声生物制药有限公司 抗FGFR2b抗体-药物缀合物及其应用
CN120424212A (zh) * 2024-01-26 2025-08-05 上海安领科生物医药有限公司 抗FGFR2b抗体及抗体药物偶联物
CN117925825B (zh) * 2024-01-31 2024-09-13 中国医学科学院北京协和医院 包含ncoa7的标志物组合在诊断圆锥角膜中的应用
WO2025218662A1 (zh) * 2024-04-16 2025-10-23 杭州中美华东制药有限公司 抗成纤维细胞生长因子受体2b的抗体及其用途

Family Cites Families (106)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5981216A (en) 1985-04-01 1999-11-09 Alusuisse Holdings A.G. Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
US6548640B1 (en) 1986-03-27 2003-04-15 Btg International Limited Altered antibodies
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
HU215581B (hu) 1989-07-06 1999-01-28 Regents Of The University Of California Eljárás fibroblaszt növekedési faktor receptorok előállítására és terápiás alkalmazására
US6713610B1 (en) 1990-01-12 2004-03-30 Raju Kucherlapati Human antibodies derived from immunized xenomice
US6673986B1 (en) 1990-01-12 2004-01-06 Abgenix, Inc. Generation of xenogeneic antibodies
US5863888A (en) 1990-07-06 1999-01-26 Rhone-Poulenc Rorer Pharmaceuticals Inc. Human Bek Fibroblast growth factor receptor
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5874299A (en) 1990-08-29 1999-02-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5877397A (en) 1990-08-29 1999-03-02 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US6300129B1 (en) 1990-08-29 2001-10-09 Genpharm International Transgenic non-human animals for producing heterologous antibodies
US6255458B1 (en) 1990-08-29 2001-07-03 Genpharm International High affinity human antibodies and human antibodies against digoxin
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
GB9603256D0 (en) 1996-02-16 1996-04-17 Wellcome Found Antibodies
WO1997048813A2 (en) 1996-06-18 1997-12-24 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Fibroblast growth factor receptor activating gene 1 (frag1). fgfr2-frag1 fusions
ES2244066T3 (es) 1997-06-24 2005-12-01 Genentech, Inc. Procedimiento y composiciones de glicoproteinas galactosiladas.
US6342220B1 (en) 1997-08-25 2002-01-29 Genentech, Inc. Agonist antibodies
AU759779B2 (en) 1997-10-31 2003-05-01 Genentech Inc. Methods and compositions comprising glycoprotein glycoforms
DK1034298T3 (da) 1997-12-05 2012-01-30 Scripps Research Inst Humanisering af murint antistof
DK1071700T3 (da) 1998-04-20 2010-06-07 Glycart Biotechnology Ag Glykosylerings-modifikation af antistoffer til forbedring af antistofafhængig cellulær cytotoksicitet
US6737056B1 (en) 1999-01-15 2004-05-18 Genentech, Inc. Polypeptide variants with altered effector function
CA2704600C (en) 1999-04-09 2016-10-25 Kyowa Kirin Co., Ltd. A method for producing antibodies with increased adcc activity
US6342219B1 (en) 1999-04-28 2002-01-29 Board Of Regents, The University Of Texas System Antibody compositions for selectively inhibiting VEGF
EP1229125A4 (en) 1999-10-19 2005-06-01 Kyowa Hakko Kogyo Kk PROCESS FOR PREPARING A POLYPEPTIDE
JP2001302699A (ja) 2000-04-17 2001-10-31 Nichirei Corp ヒトkgfrに対する抗体
CA2953239A1 (en) 2000-10-06 2002-04-18 Kyowa Hakko Kirin Co., Ltd. Antibody composition-producing cell
US6946292B2 (en) 2000-10-06 2005-09-20 Kyowa Hakko Kogyo Co., Ltd. Cells producing antibody compositions with increased antibody dependent cytotoxic activity
US7064191B2 (en) 2000-10-06 2006-06-20 Kyowa Hakko Kogyo Co., Ltd. Process for purifying antibody
CA2450793A1 (en) 2001-06-20 2002-12-27 Prochon Biotech Ltd. Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof
NZ571596A (en) 2001-08-03 2010-11-26 Glycart Biotechnology Ag Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity
CA2463879C (en) 2001-10-25 2012-12-04 Genentech, Inc. Glycoprotein compositions
US20040093621A1 (en) 2001-12-25 2004-05-13 Kyowa Hakko Kogyo Co., Ltd Antibody composition which specifically binds to CD20
EP1469878B1 (en) 2002-01-31 2011-03-23 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Fgfr agonists
AU2003210060B2 (en) 2002-03-22 2010-02-25 Aprogen, Inc. Humanized antibody and process for preparing same
CA2481925A1 (en) 2002-04-09 2003-10-16 Kyowa Hakko Kogyo Co., Ltd. Therapeutic agent for patients having human fc.gamma.riiia
EP1500400A4 (en) 2002-04-09 2006-10-11 Kyowa Hakko Kogyo Kk MEDICAMENT WITH ANTIBODY COMPOSITION
ATE503829T1 (de) 2002-04-09 2011-04-15 Kyowa Hakko Kirin Co Ltd Zelle mit erniedrigter oder deletierter aktivität eines am gdp-fucosetransport beteiligten proteins
CA2481658A1 (en) 2002-04-09 2003-10-16 Kyowa Hakko Kogyo Co., Ltd. Method of enhancing of binding activity of antibody composition to fcy receptor iiia
BR0309145A (pt) 2002-04-09 2005-02-01 Kyowa Hakko Kogyo Kk Células das quais o genoma é modificado
EP1498490A4 (en) 2002-04-09 2006-11-29 Kyowa Hakko Kogyo Kk PROCESS FOR PREPARING ANTIBODY COMPOSITION
KR100493460B1 (ko) 2002-08-29 2005-06-07 재단법인서울대학교산학협력재단 암 세포에서 발현되는 fgfr2 이성체
TWI335821B (en) 2002-12-16 2011-01-11 Genentech Inc Immunoglobulin variants and uses thereof
JPWO2005035586A1 (ja) 2003-10-08 2007-11-22 協和醗酵工業株式会社 融合蛋白質組成物
JPWO2005035778A1 (ja) 2003-10-09 2006-12-21 協和醗酵工業株式会社 α1,6−フコシルトランスフェラーゼの機能を抑制するRNAを用いた抗体組成物の製造法
EP2060270A3 (en) 2003-10-16 2009-12-09 Imclone LLC Fibroblast growth factor receptor-1 inhibitors and methods of treatment thereof
CA2541651C (en) 2003-10-22 2011-05-24 Keck Graduate Institute Methods of synthesizing heteromultimeric polypeptides in yeast using a haploid mating strategy
US9296820B2 (en) 2003-11-05 2016-03-29 Roche Glycart Ag Polynucleotides encoding anti-CD20 antigen binding molecules with increased Fc receptor binding affinity and effector function
WO2005053742A1 (ja) 2003-12-04 2005-06-16 Kyowa Hakko Kogyo Co., Ltd. 抗体組成物を含有する医薬
EP1697420A2 (en) 2003-12-19 2006-09-06 Five Prime Therapeutics, Inc. Fibroblast growth factor receptors 1, 2, 3, and 4 as targets for therapeutic intervention
EP1740615B1 (en) 2004-03-31 2014-11-05 Genentech, Inc. Humanized anti-tgf-beta antibodies
WO2005115363A2 (en) 2004-05-25 2005-12-08 Yale University Method for treating skeletal disorders resulting from fgfr malfunction
WO2006076288A2 (en) 2005-01-11 2006-07-20 Five Prime Therapeutics, Inc. Dna constructs for long-term expression of intravascularly injected naked dna
US7923538B2 (en) 2005-07-22 2011-04-12 Kyowa Hakko Kirin Co., Ltd Recombinant antibody composition
CA2648021A1 (en) 2006-03-31 2007-10-11 Ordway Research Institute, Inc. Prognostic and diagnostic method for cancer therapy
JP2009536834A (ja) 2006-05-12 2009-10-22 ジェネンテック・インコーポレーテッド 癌の診断及び治療のための方法及び組成物
WO2007146847A2 (en) 2006-06-09 2007-12-21 University Of Maryland, Baltimore Glycosylation engineered antibody therapy
US8101721B2 (en) 2006-06-15 2012-01-24 Fibron Ltd. Antibodies blocking fibroblast growth factor receptor activation and methods of use thereof
AR062223A1 (es) 2006-08-09 2008-10-22 Glycart Biotechnology Ag Moleculas de adhesion al antigeno que se adhieren a egfr, vectores que los codifican, y sus usos de estas
DK2066694T3 (en) 2006-09-29 2016-02-08 Oncomed Pharm Inc Compositions and Methods for Diagnosing and Treating Cancer
EP2094733A1 (en) 2006-11-03 2009-09-02 U3 Pharma GmbH Fgfr4 antibodies
AR063975A1 (es) 2006-11-28 2009-03-04 Centelion Fusiones fc con receptor para fgf soluble modificadas con actividad biologica mejorada
AR064464A1 (es) 2006-12-22 2009-04-01 Genentech Inc Anticuerpos anti - receptor del factor de crecimiento insulinico
US20080226635A1 (en) 2006-12-22 2008-09-18 Hans Koll Antibodies against insulin-like growth factor I receptor and uses thereof
AU2008208288B2 (en) 2007-01-24 2014-04-03 Kyowa Kirin Co., Ltd. Genetically recombinant antibody composition having enhanced effector activity
CA2680046A1 (en) 2007-03-23 2008-10-02 The Translational Genomics Research Institute Methods of diagnosing, classifying and treating endometrial cancer and precancer
CA2682382A1 (en) 2007-03-28 2008-10-09 Biogen Idec Inc. Non-fucosylated antibodies
EP2205277B1 (en) 2007-10-22 2017-07-26 Genmab A/S Novel antibody therapies
WO2009100105A2 (en) 2008-02-04 2009-08-13 Attogen Inc. Inhibitors of oncogenic isoforms and uses thereof
US9260525B2 (en) 2008-02-04 2016-02-16 Xiao-Jia Chang Antibody molecules to oncogenic isoforms of fibroblast growth factor receptor-2 and uses thereof
WO2009151448A1 (en) 2008-06-10 2009-12-17 University Of Southern California Thymidylate synthase haplotype is associated with tumor recurrence in stage ii and stage iii colon cancer patients
EP2177615A1 (en) 2008-10-10 2010-04-21 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Method for a genome wide identification of expression regulatory sequences and use of genes and molecules derived thereof for the diagnosis and therapy of metabolic and/or tumorous diseases
HUE035700T2 (en) 2008-11-07 2018-05-28 Galaxy Biotech Llc Monoclonal antibodies to Fibroblast Growth Factor receptor 2
US20120301482A1 (en) 2009-08-25 2012-11-29 National Jewish Health Methods and compositions for treatment of lung injury
CA2777068C (en) 2009-10-14 2020-05-26 Humanigen, Inc. Antibodies to epha3
RU2012134637A (ru) 2010-01-14 2014-02-20 Йейл Юниверсити Ингибиторы рецепторных тирозинкиназ (rtk) и способы их применения
US9140689B2 (en) 2010-03-14 2015-09-22 Translational Genomics Research Institute Methods of determining susceptibility of tumors to tyrosine kinase inhibitors
RU2012153241A (ru) 2010-05-11 2014-06-20 Авео Фармасьютикалз, Инк. Антитела к fgfr2
US8907053B2 (en) 2010-06-25 2014-12-09 Aurigene Discovery Technologies Limited Immunosuppression modulating compounds
EP2603521A4 (en) 2010-08-12 2014-10-01 Attogen Inc ANTIBODY MOLECULARS FOR ONGOGEN FIBROBLAST GROWTH RECEPTOR 2 ISOFORMS AND ITS USES
US20120258496A1 (en) 2010-09-27 2012-10-11 Boehringer Ingelheim International Gmbh Production of low fucose antibodies in h4-ii-e rat cells
EP3828205A1 (en) 2010-10-01 2021-06-02 Oxford BioTherapeutics Ltd Anti-ror1 antibodies
EP2714738B1 (en) * 2011-05-24 2018-10-10 Zyngenia, Inc. Multivalent and monovalent multispecific complexes and their uses
AR088941A1 (es) 2011-11-23 2014-07-16 Bayer Ip Gmbh Anticuerpos anti-fgfr2 y sus usos
SG11201403085PA (en) 2011-12-14 2014-10-30 Seattle Genetics Inc Fgfr antibody drug conjugates (adcs) and the use thereof
WO2013148263A1 (en) 2012-03-30 2013-10-03 The Regents Of The University Of California Anti-emp2 therapy reduces cancer stem cells
AU2013247645B2 (en) 2012-04-09 2019-02-14 Daiichi Sankyo Company, Limited Anti-FGFR2 antibody
US9254288B2 (en) 2012-05-07 2016-02-09 The Translational Genomics Research Institute Susceptibility of tumors to tyrosine kinase inhibitors and treatment thereof
HK1203971A1 (en) 2012-05-15 2015-11-06 Bristol-Myers Squibb Company Cancer immunotherapy by disrupting pd-1/pd-l1 signaling
US20150191791A1 (en) 2012-07-05 2015-07-09 Lsip, Llc Fgfr2 fusion gene
WO2014089193A1 (en) 2012-12-04 2014-06-12 Aveo Pharmaceuticals, Inc. Anti-fgfr2 antibodies
CA3150658A1 (en) 2013-01-18 2014-07-24 Foundation Medicine, Inc. Methods of treating cholangiocarcinoma
US9498532B2 (en) 2013-03-13 2016-11-22 Novartis Ag Antibody drug conjugates
US9415118B2 (en) 2013-03-13 2016-08-16 Novartis Ag Antibody drug conjugates
US20160067307A1 (en) 2013-05-01 2016-03-10 Five Prime Therapeutics, Inc. Methods of treating cancer
US20160130661A1 (en) 2013-06-13 2016-05-12 University Of South Australia Methods for detecting prostate cancer
KR102516152B1 (ko) 2013-08-01 2023-03-31 파이브 프라임 테라퓨틱스, 인크. 비푸코실화된 항-fgfr2iiib 항체
PE20170255A1 (es) 2014-01-24 2017-03-22 Dana Farber Cancer Inst Inc Moleculas de anticuerpo que se unen a pd-1 y usos de las mismas
WO2015116868A2 (en) 2014-01-29 2015-08-06 Caris Mpi, Inc. Molecular profiling of immune modulators
CA2961439A1 (en) 2014-11-05 2016-05-12 Genentech, Inc. Anti-fgfr2/3 antibodies and methods using same
EP3233918A1 (en) 2014-12-19 2017-10-25 Novartis AG Combination therapies
US10478494B2 (en) 2015-04-03 2019-11-19 Astex Therapeutics Ltd FGFR/PD-1 combination therapy for the treatment of cancer
MX2018006181A (es) 2015-11-23 2018-09-24 Five Prime Therapeutics Inc Inhibidores de fgfr2 solos o en combinacion con agentes que estimulan el sistema inmunitario en el tratamiento contra el cancer.
PT3624837T (pt) 2017-05-16 2025-10-01 Five Prime Therapeutics Inc Anticorpos anti-fgfr2 em combinação com agentes quimioterapêuticos no tratamento do cancro

Similar Documents

Publication Publication Date Title
JP2023093527A5 (https=)
JP2025004195A5 (https=)
FI3624837T3 (fi) Anti-fgfr2-vasta-aineita yhdistelmässä kemoterapia-aineiden kanssa syövän hoidossa
CN108601831B (zh) 一种抗pd-1抗体和vegfr抑制剂联合在制备治疗癌症的药物中的用途
JP2023511595A5 (https=)
CN111065411A (zh) Pd-1抗体和vegfr抑制剂联合治疗小细胞肺癌的用途
JP2018521976A5 (https=)
JP2019517549A5 (https=)
JP2020508317A5 (https=)
FI3463345T3 (fi) Farmaseuttisia yhdistelmiä
JP2014500278A5 (https=)
JP2015500822A5 (https=)
TW201536319A (zh) 抗腫瘤劑及抗腫瘤效果增強劑
JP2022501332A5 (https=)
JP2021511344A5 (https=)
US20120020989A1 (en) Methods of treating colorectal cancer
Wang et al. Treatment strategies for patients with HER2-positive gastric cancer
CN112121048A (zh) 用于联合治疗食管癌的喹啉类化合物
CN117083086A (zh) 腺苷二磷酸核糖在放射和/或抗癌治疗辅助疗法中的应用
JP2024514087A5 (https=)
JP2020521798A5 (https=)
WO2025103379A1 (zh) 抗b7h3抗体-药物偶联物治疗癌症的方法
JP2023500480A5 (https=)
CN112043832A (zh) 用于联合治疗胃癌的喹啉类化合物
CN112955148A (zh) Cdk4/6抑制剂联合免疫治疗在制备治疗淋巴瘤的药物中的用途