JP2023041946A - Dosage device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a liquid ejecting apparatus that can eject a predetermined amount of a very small amount of liquid.

SOLUTION: A liquid ejecting apparatus has a liquid storage part, a tube member, a hitting part, and an operation part. Liquid is ejected from an ejection port. In the tube member, the inside of the liquid storage part is brought into communication with one end, and the liquid is sent from the liquid storage part toward an ejection port side. The tube member has an elastically deformable elastic domain in at least a portion in the longitudinal direction. At least a portion of the elastic domain of the tube member is hit by the hitting part by operating the operation part, and thereby the liquid in the tube member is pushed out of the ejection port and is ejected.

SELECTED DRAWING: Figure 10

COPYRIGHT: (C)2023,JPO&INPIT

Description

The present invention relates to a liquid ejecting apparatus that ejects a very small amount of liquid. The present invention also relates to a drug administration device that can be suitably used when administering a very small amount of liquid medicine, such as eye drops, to a patient's eyeball or the like.

2. Description of the Related Art In recent years, with the aging of patients, there has been an increase in the number of patients who cannot face upward to instill eye drops or who cannot accurately instill eye drops onto the surface of the eyeball. In addition, rheumatism patients and patients with poor grip strength may not be able to push the eyedropper by themselves or open the eyedropper.

In addition, it is said that the maximum amount of eye drops that can be retained on the surface of a human eyeball is only about 7 μL. Therefore, if 25 to 50 μL of eye drops are administered dropwise as in the conventional method, excess eye drops inevitably flow out of the eye, and not only is the drug not effectively utilized, but it is absorbed by the tissues surrounding the eye. and side effects associated with systemic migration.

Therefore, spectacle-type ophthalmic devices for administering a small amount of medicine to the eyes have been proposed (Patent Documents 1 and 2).
In Patent Document 1, a thermal jet dispenser is adopted as a liquid injection means (see FIGS. 5 and 6 of Patent Document 1), and in Patent Document 2, a piezojet dispenser or a thermal jet dispenser is used. is adopted.

WO 1994/003135 Japanese Unexamined Patent Application Publication No. 2005-21701

However, the flight distance of the liquid medicine by the thermal jet method and the piezo jet method as in Patent Documents 1 and 2 is only about several millimeters in the horizontal direction, and the ejection port must be brought close to the eyeball. Therefore, when administering medication directly by one's own hand or by a third party such as a doctor, it is difficult to administer medication while facing the front, and there is a problem of poor administration accuracy. In addition, the apparatus and the like are complicated, which raises the problem of high product cost.

SUMMARY OF THE INVENTION Accordingly, it is an object of the present invention to provide a liquid ejecting apparatus capable of ejecting a predetermined amount of very small amount of liquid. Another object of the present invention is to provide a drug administration device that enables even a person who has difficulty in administering a drug solution, a doctor, or the like to easily administer a prescribed amount of a very small amount of a drug solution.

The invention according to claim 1 for solving the above-mentioned problems has a liquid storage part, a tube member, a hitting part, a hit part, and an operation part, and a liquid is discharged from a discharge port. In the liquid ejection device, the tube member communicates with the inside of the liquid storage portion at one end thereof, and feeds the liquid from the liquid storage portion toward the ejection port side, and the tube member In the longitudinal direction, there is an elastic region that is elastically deformable in at least a part thereof, and by operating the operation part, the tube member is positioned between the striking part and the struck part and moves toward the struck part. From the positioned state, the hit part does not move with respect to the hit part, and the hit part hits at least a part of the elastic region of the tube member to move the tube member to the hit target. The tube member is pressed against the striking part to sandwich the tube member together with the part to be struck, and the liquid in the tube member is pushed out from the ejection port to be ejected. The liquid ejecting device is characterized in that the shape of the tube member is restored from the state elastically deformed by the pressing force of the portion, so that the liquid is replenished from the liquid storage portion by capillary action.
An invention related to the present invention is a liquid ejection device that includes a liquid storage portion, a tube member, a striking portion, and an operation portion, and ejects liquid from an ejection port, wherein the tube member includes the liquid. One end of the tube member communicates with the inside of the storage section, and the liquid is fed from the liquid storage section toward the ejection port side. At least a part of the elastic region of the tube member is struck by the striking section by operating the operation section, and the liquid in the tube member is pushed out from the ejection port to be ejected. A discharge device.

The term "strike" as used herein refers to hitting with an impact.
The term "liquid" as used herein refers to fluidity, and includes chemical solutions, oils, water, organic solvents, aqueous solutions, ionic liquids, and the like.

An invention related to the present invention is a liquid ejection device in which the tube member transports the liquid from the liquid storage portion toward the ejection port side by capillary action.

An invention related to the present invention is a liquid ejecting device in which the entire area of the tube member constitutes the elastic region.

In the invention according to claim 2, the elastic region is selected from the group consisting of polyethylene, polypropylene, silicone, fluororubber, polytetrafluoroethylene, nylon, polyethylene terephthalate, polybutylene terephthalate, polyethylene naphthalate, natural rubber, and synthetic rubber. 2. The liquid ejector of claim 1, wherein the liquid ejector is constructed of at least one selected elastic material.

The invention according to claim 3 has a biasing member that biases the striking portion toward the elastic region, and by operating the operation portion, the striking portion is pushed from the biasing member. 3. The liquid ejecting apparatus according to claim 1, wherein the striking portion is moved or changed in attitude against an urging force, and the striking portion strikes the elastic region by the urging force.

In the invention according to claim 4, the maximum inner diameter of the elastic region of the tube member is 0.1 mm or more and 2 mm or less, and the amount of liquid discharged from the discharge port when the operation part is operated once is , 0.01 μL or more and 7 μL or less.

As used herein, the term "maximum inner diameter" refers to the minimum diameter of a circle that includes the internal space of the tube member in a cross section orthogonal to the extending direction of the tube member, and refers to the diameter of the minimum circle that includes the entire internal space.

According to a fourth aspect of the present invention, the amount of liquid ejected from the ejection port when the operation portion is operated once is 0.01 μL or more and 7 μL or less.
The invention according to claim 5 is the liquid ejection apparatus according to claim 4, characterized in that the amount of liquid ejected from the ejection port when the operation unit is operated once is less than 1 μL. .
According to a sixth aspect of the present invention, the amount of liquid ejected from the ejection port is 0.625 μL or less when the operating portion is operated once. is.
The above invention relates to a liquid ejecting apparatus in which the amount of liquid ejected from the ejection port is 0.01 μL or more and 100 μL or less when the operation portion is operated once.

The invention according to claim 7 is characterized in that the range of hitting by the hitting part of the tube member is 1 mm or more and 30 mm or less in the longitudinal direction. 10. A liquid ejecting apparatus according to claim 1.

According to an eighth aspect of the invention, when the operation part is operated with the ejection port facing in the horizontal direction, the liquid is substantially in a range of at least more than 0 cm and 0.5 cm or less from the ejection port. 8. The liquid ejecting apparatus according to any one of claims 1 to 7, wherein the liquid is ejected in a straight line.

The term "substantially linear" as used herein includes not only the case of being completely linear, but also the case of being slightly curved due to the influence of gravity and the like to the extent that it can be regarded as being substantially straight. Specifically, the angle of the straight line connecting the start point (liquid ejection port) and the end point is 5 degrees or less, preferably 3 degrees or less, and more preferably 1 degree or less.

According to a ninth aspect of the invention, there is provided a body portion and a liquid cartridge, the body portion including the striking portion and the operating portion, and the liquid cartridge including the liquid storage portion and the tube member. , and is detachable from the main body.

According to a tenth aspect of the invention, there is provided a case portion that accommodates at least a portion of the tube member so as to incorporate the discharge port, and a device that moves or takes a posture relative to the case portion in conjunction with the operating portion. It has a closing part that changes, the case part has a liquid passage hole at a position facing the discharge port, the closing part has an operation side through hole, and by operating the operation part, A closed state in which the closing portion closes the liquid passage hole, and an open state in which the operation-side through hole is linearly aligned with the liquid passage hole and the liquid passage hole is opened as the closing portion moves or changes its posture. 10. The liquid ejecting apparatus according to any one of claims 1 to 9, characterized in that it can be changed between .
An invention related to the present invention is a case portion that accommodates at least a part of the tube member so as to incorporate the discharge port, and a case portion that is interlocked with the operation portion to move or change the posture relative to the case portion. The case portion has a liquid passage hole at a position facing the discharge port, and by operating the operating portion, the liquid passage hole is closed by the closing portion. and an open state in which the closing portion moves or changes its attitude to open the liquid passage hole.

According to an eleventh aspect of the invention, there is provided a liquid ejecting device including a liquid storage portion, a tube member, a striking portion, a struck portion, and an operating portion, wherein the liquid is ejected from an ejection port, One end of the tube member communicates with the interior of the liquid storage section, and feeds the liquid from the liquid storage section toward the ejection port side. There is an elastic region that can be elastically deformed, and by operating the operation part, the tube member is positioned between the striking part and the struck part and on the side of the struck part, and the tube member moves from the state where the tube member is positioned on the side of the struck part. The hitting part hits at least a part of the elastic region of the tube member without moving with respect to the hitting part, and presses the tube member toward the hit part, The tube member is sandwiched together with the hit portion, and the liquid in the tube member is pushed out and discharged from the discharge port. A striking fixing portion is provided, the operating portion has an operating side engaging portion, the striking member has the striking portion and a connecting portion, and the striking fixing portion of the case member is provided. the connection portion is held by a portion and the striking portion is cantilevered so as to extend from the connection portion, the elastic region of the tubular member being higher than the connection portion; By operating the operation part, the operating side engaging part presses the striking part, the striking part is elastically deformed, and the restoring force causes the striking part to move at least a part of the elastic region. The liquid ejection device is characterized by impact.
An invention related to the present invention has a case member and a striking member having the striking portion, the striking member has a connecting portion, and the connecting portion is held by the case member and cantilevered. The elastic region of the tube member is positioned higher than the connection portion. By operating the operation portion, the impact portion is elastically deformed, and the restoring force of the impact portion causes the impact to occur. In the liquid ejection device, the hitting part hits at least part of the elastic region.

According to a 12th aspect of the invention, there is provided a dispensing device using the liquid ejection device according to any one of the 1st to 11th aspects, wherein the liquid is a drug solution. .

According to the liquid ejecting apparatus of the present invention, it is possible to eject a predetermined minute amount of liquid.
According to the drug administration device of the present invention, even a person who has difficulty in drug administration can easily administer medication by a doctor or the like at the time of examination.

It is a side view which shows the general usage condition of the injection device of 1st Embodiment of this invention. Figure 2 is a perspective view of the dispensing device of Figure 1; Figure 3 is an exploded perspective view of the dispensing device of Figure 2; FIG. 4 is a perspective view of the second case portion of FIG. 3 as seen from a direction different from that of FIG. 3 ; FIG. 4 is a perspective view of the striking member of FIG. 3 as seen from a direction different from that of FIG. 3; 4 is a cross-sectional perspective view of the chemical solution unit of FIG. 3; FIG. FIG. 4 is a perspective view of the liquid medicine unit of FIG. 3 as seen from a direction different from that of FIG. 3 ; 4 is a bottom view of the chemical solution unit of FIG. 3; FIG. Fig. 3 is a side view of the dispensing device with the second case part of Fig. 2 removed; FIG. 2 is an explanatory view of the drug administration device when administering a drug solution using the drug administration device of FIG. 1, (a) is a side view showing the state when the operating section is operated, and (b) is a biasing member. FIG. 10A is a side view showing a state in which the operating portion is returned by the biasing force, and FIG. are depicted with the second case removed. 11A to 11D are cross-sectional views showing the flow of the drug solution near the tube member when the drug solution is administered using the drug administration device of FIG. Note that the chemical solution is indicated by dots. Fig. 10 is an exploded perspective view of a dispensing device according to a second embodiment of the present invention; FIG. 12 is an explanatory view of the drug administration device when administering a drug solution using the drug administration device of FIG. 12, (a) to (c) are side views showing each process when the first operation unit is pressed, (a) to (c) are drawn without the second case portion. 13D is a side view showing the process following FIG. 13C when the first operation unit is pressed; FIG. (e) and (f) are side views when the second operation portion is pressed after the first operation portion is pressed, and (d) to (f) are all with the second case portion removed. is depicted. Fig. 10 is an exploded perspective view of a dispensing device according to a third embodiment of the present invention; 16A to 16C are explanatory diagrams of the dispensing device when administering a drug solution using the dispensing device of FIG. ) to (c) are drawn with the second case removed. 16A and 16B are explanatory views of the dispensing device when administering a liquid medicine using the dispensing device of FIG. 15, and (d) and (e) are side views showing the steps following FIG. 16(c) when the operation unit is pressed. It is a figure, and both (d) and (e) are depicted with the second case portion removed. FIG. 12A is a perspective view of a drug administration device according to a fourth embodiment of the present invention, where (a) is a perspective view of a closed state before a discharge operation, and (b) is a perspective view of an open state during discharge. FIG. 19 is an exploded perspective view of the dispensing device of FIG. 18 viewed from a direction different from that of FIG. 18; 20 is an exploded perspective view of the main body of FIG. 19 viewed from the same direction as that of FIG. 18; FIG. FIG. 18(a) is a cross-sectional view of the dispensing device of FIG. 18(a) taken along line AA. FIG. 21 is a perspective view of the case member of FIG. 20; FIG. 21 is a perspective view of the case portion of FIG. 20; Figure 21 is a perspective view of the operating member of Figure 20; FIG. 20 is a perspective view of the liquid cartridge of FIG. 19 as seen from a direction different from that of FIG. 19; 19A and 19B are cross-sectional views showing the positional relationship in each procedure; FIG. FIG. 27 is an explanatory diagram of the operation procedure of the dispensing device following FIG. 26, and (c) and (d) are cross-sectional views showing the positional relationship in each procedure; FIG. 28 is an explanatory diagram of the operation procedure of the dispensing device following FIG. 27, and (e) and (f) are sectional views showing the positional relationship in each procedure; FIG. 10A is a perspective view of a dispensing device according to a fifth embodiment of the present invention, in which (a) is a perspective view of a closed state before a discharge operation, and (b) is a perspective view of an open state during discharge. FIG. 30 is an exploded perspective view of the dispensing device of FIG. 29 viewed from a direction different from that of FIG. 29; It is explanatory drawing of tube member vicinity of other embodiment of this invention, (a), (b) represents different embodiment. Figure 4 is a cross-sectional perspective view of a tube member according to another embodiment of the invention; FIG. 4 is a cross-sectional perspective view of a chemical liquid unit according to another embodiment of the present invention;

BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, embodiments of the present invention will be described in detail. In the following description, unless otherwise specified, the posture (vertical posture) of FIG. 1 is used as a reference, the patient's eyeball 101 side is the front side, and the distal side as seen from the patient is the rear side.

As shown in FIGS. 1 and 2, the dispensing device 1 (liquid ejecting device) of the first embodiment of the present invention is provided with an ejection port 8 on the end face, and liquid droplets are discharged from the ejection port 8 onto the surface of the eyeball 101 of the patient. It administers the medical solution 100 .
As shown in FIG. 1, the dispensing device 1 can eject the drug solution 100 horizontally from the ejection port 8 in a horizontal posture in which the ejection port 8 faces the horizontal direction. One of the features is that the drug solution 100 can be administered regardless of the patient's posture.

The dispensing device 1 includes, as main components, a case member 2, a striking member 3, a liquid medicine unit 4, an urging member 7, and a discharge port 8, as shown in FIGS.
The chemical liquid unit 4 is mainly composed of a chemical liquid storage section 5 (liquid storage section) and a tube member 6 .

The case member 2 is composed of a first case portion 10 and a second case portion 11 as shown in FIG.
The first case portion 10 includes a body wall portion 20 , side wall portions 21 to 24 and a shaft portion 25 .
The main body wall portion 20 is a substantially rectangular wall portion, and the side wall portions 21 to 24 are vertical wall portions rising from each side of the main body wall portion 20 .
The shaft portion 25 is a rod-shaped portion erected with respect to the main body wall portion 20, and serves as a rotating shaft of the striking member 3 during assembly. The shaft portion 25 also serves as a fixing portion that fixes the biasing member 7 .

The second case portion 11 includes a main body wall portion 30, side wall portions 31 to 34, a guide groove 35, and a shaft fixing hole 36, as shown in FIG.
The main body wall portion 30 is a substantially rectangular wall portion, and the side wall portions 31 to 34 are vertical wall portions rising from respective sides of the main body wall portion 30 .

The guide groove 35 is a groove that guides the striking member 3, and is a through groove that is provided in the main body wall portion 30 and penetrates the main body wall portion 30 in the thickness direction. When the main body wall portion 30 is viewed from the front, the guide groove 35 extends in an arc shape in the circumferential direction around the shaft fixing hole 36 .
The shaft fixing hole 36 is a bearing hole for receiving the end portion of the shaft portion 25 of the first case portion 10 as shown in FIG.

The impacting member 3 includes a body portion 50, an impacting portion 51, an operating portion 52, and a shaft hole 53, as shown in FIG.
The main body portion 50 is a substantially V-shaped hammer piece, and includes a first extending portion 55 and a second extending portion 56 extending obliquely from the end portion of the first extending portion 55 .
The first extending portion 55 has a fixing portion 57 capable of fixing the end portion of the biasing member 7 .

The hitting part 51 is a part that hits a part of the tube member 6 and ejects the liquid medicine 100 from the ejection port 8 . That is, the impact part 51 is a part that partially presses the tube member 6 and forcibly ejects the drug solution 100 in the tube member 6 from the ejection port 8 .
As shown in FIG. 5 , the striking portion 51 includes a flat portion 58 and a convex portion 59 projecting from the flat portion 58 .
The projection 59 is a projection that forms a pair with the recess 69 of the drug solution reservoir 5 and extends across the tube member 6 when assembled. That is, the convex portion 59 extends in a direction crossing the extending direction of the tube member 6 and is provided on the upstream side of the hitting portion 51 in the flow direction of the liquid medicine 100 of the tube member 6 by capillary action.

The operation part 52 is a part for operating the striking part 51 , and is a rod-shaped part provided on the second extension part 56 and erected with respect to the second extension part 56 .
The shaft hole 53 is an insertion hole into which the shaft portion 25 can be inserted, and is a through hole provided on the base end side of the first extension portion 55 and penetrating the first extension portion 55 in the thickness direction.

The chemical storage unit 5 is a container having a storage space 65 capable of storing the chemical 100, as shown in FIG.

The drug solution storage unit 5 includes a body portion 60 and a cap portion 61 as shown in FIG.
The body portion 60 includes a hit portion 62, a storage hole 63, and a communication hole 64, as shown in FIGS.
The struck portion 62 is a portion that is struck by the striking portion 51 of the striking member 3 via the tube member 6, and includes a flat portion 68 and a recessed portion 69 recessed from the flat portion 68. .
The recessed portion 69 is a recessed groove that extends across the tube member 6 when assembled, and extends in a direction that intersects the extending direction of the tube member 6 .

The storage hole 63 is a bottomed hole having a linear depth in the front-rear direction from the front end surface of the chemical storage unit 5, and is a hole that communicates the storage space 65 with the outside.
The communication hole 64 is a through hole that communicates between the storage space 65 and the outside, extends vertically or obliquely from the outside toward the storage space 65, and is also an insertion hole into which the tube member 6 can be inserted.

The cap portion 61 is a closing portion for closing the storage hole 63 and has a through hole 66 as shown in FIG.
The through-hole 66 is an air hole for introducing air into the storage space 65 from the outside, and is a through-hole penetrating in the thickness direction. That is, the through-hole 66 is a hole for introducing the outside air into the storage space 65 and always keeping the internal pressure and the external pressure in the chemical storage section 5 equal.
The perimeter of the through-hole 66 may be treated with a hydrophilic treatment or a hydrophobic treatment to prevent the liquid medicine 100 from leaking from the through-hole 66, if necessary. By doing so, the liquid medicine 100 can be made more difficult to leak from the through-holes 66 .

As shown in FIG. 6 , the tube member 6 is a member having one end inserted into the liquid medicine reservoir 5 and the other end forming a discharge port 8 . 100 is a liquid delivery tube.
The tube member 6 is a cylindrical body having a hollow interior and extending with a length. The tube member 6 of this embodiment is a cylindrical tube and has a circular cross-sectional shape.
The tube member 6 has an elastic region in which at least a part thereof in the longitudinal direction is made of an elastic body, and the elastic region is elastically deformable in a direction intersecting the longitudinal direction.
The tube member 6 of this embodiment has an elastic region over the entire longitudinal direction.

The tube member 6 is not particularly limited as long as it is elastically deformable. Examples of the tube member 6 include polyethylene, polypropylene, silicon, fluororubber, polytetrafluoroethylene, nylon, polyethylene terephthalate, polybutylene terephthalate, and polyethylene naphthalate. , natural rubber, and synthetic rubber.
By using these elastic materials, a desired amount of the chemical solution 100 can be discharged with good reproducibility.
Further, from the viewpoint of replenishing the liquid medicine 100 inside by capillary action, the tube member 6 preferably has lipophilicity if the liquid medicine is an oil-based formulation, and hydrophilicity if the liquid medicine is an aqueous formulation.

The inner diameter (maximum inner diameter) of the tube member 6, that is, the minimum circular diameter of the internal space of the tube member 6 in a cross section perpendicular to the extending direction of the tube member 6, may be within a range in which the liquid medicine 100 can be transferred by capillary action. It is preferably 1 mm or more and 2 mm or less, more preferably 0.3 mm or more and 1 mm or less.
The outer diameter (maximum outer diameter) of the tube member 6, that is, the minimum enclosing circle diameter of the outer surface of the tube member 6 in a cross section perpendicular to the extending direction of the tube member 6, exceeds the inner diameter of the tube member 6, and is 0.2 mm or more. It is preferably 5 mm or less.
The thickness (difference between the outer diameter and the inner diameter) of the tube member 6 is preferably 0.05 mm or more and 3 mm or less.
Within these ranges, the pressing force from the impacting portion 51 is not excessively absorbed in the tube member 6, and can be efficiently transmitted to the liquid medicine 100 inside.

The wetted inner surface of the tube member 6 may be subjected to hydrophobic treatment or hydrophilic treatment as necessary.

The biasing member 7 is a member that biases the striking portion 51 toward the liquid medicine storage portion 5 side.
Specifically, the biasing member 7 includes a coil portion 80 and arm portions 81 and 82 extending from the coil portion 80 as shown in FIG. Spring.
The coil portion 80 is an annular portion, into which the shaft portion 25 can be inserted.
Arm portions 81 and 82 are rod-shaped portions extending from coil portion 80 .

The ejection port 8 is an opening through which the chemical solution 100 is ejected, and the ejection port 8 of this embodiment is configured by the end portion of the tube member 6 .

Next, the positional relationship of each member of the dispensing device 1 of the first embodiment will be described.

As shown in FIG. 3, the drug administration device 1 has a case member 2 in which a striking member 3, a liquid medicine reservoir 5, and an urging member 7 are arranged. The first case portion 10 and the second case portion 11 are fixed to each other so that the main body wall portions 20 and 30 face outward.
As shown in FIG. 2, the drug administration device 1 has side walls 21 to 24 of the first case 10 and side walls 31 to 34 of the second case 11 forming side walls 41 to 44 of the case member 2. .
As shown in FIG. 3, the shaft portion 25 of the first case portion 10 is inserted through the shaft hole 53 of the striking member 3 and the coil portion 80 of the biasing member 7, and is inserted into and fixed to the shaft fixing hole 36. . The biasing member 7 is fixed by inserting the arm portion 81 into the fixing portion 57 and the arm portion 82 is in contact with the side surface portion 43 of the case member 2 . That is, as shown in FIG. 9, the urging member 7 urges the striking member 3 in the circumferential direction so that the striking portion 51 presses the struck portion 62 of the liquid medicine storage portion 5 with the shaft portion 25 as the center. are doing.

As shown in FIG. 2 , the operating portion 52 is inserted through the guide groove 35 and partially exposed to the outside of the case member 2 . That is, as shown in FIG. 9, the operating portion 52 is restricted in its movable range by the guide groove 35 and is only allowed to move in the circumferential direction about the shaft portion 25 .
The striking part 51 receives the biasing force of the biasing member 7 and presses a portion of the tube member 6 toward the liquid medicine storage part 5 side.

As shown in FIG. 9 , the tube member 6 extends downward (diagonally downward in the present embodiment) from the liquid medicine reservoir 5 and extends toward the side surface portion 41 with a part bent.
The tube member 6 is sandwiched between the impacted portion 62 of the liquid medicine storage portion 5 and the impacting portion 51 of the impacting member 3, and receives a pressing force from the impacting portion 51 toward the impacted portion 62 side. The pressing portion 85 (FIG. 8) is elastically deformed and flattened. That is, as shown in FIG. 11A, the inside of the tube member 6 is always elastically deformed by the pressing force of the striking portion 51, and the flow path inside the pressed portion 85 is blocked, and the discharge port of the liquid medicine 100 is closed. The flow to the 8 side is cut off.
The projecting portion 59 of the hitting portion 51 presses the portion corresponding to the recessed portion 69 of the hitting portion 62 of the tube member 6 .

The length of the striking portion of the striking portion 51 shown in FIG. 8, that is, the length D of the longitudinal direction of the pressed portion 85 of the tube member 6 can be appropriately changed depending on the amount of the liquid medicine 100 to be discharged, but it is 1 mm or more. It is preferably 30 mm or less, more preferably 3 mm or more and 10 mm or less.
Within this range, the chemical solution 100 in the tube member 6 can be discharged with good reproducibility.

Next, a general process assumed when a patient administers medication to the surface of the eyeball 101 using the drug administration device 1 will be described. The dispensing device 1 can take any posture, and can administer the drug solution 100 from any direction, such as upward, downward, or sideways. A case where the chemical liquid 100 can be discharged will be described.

First, as shown in FIGS. 10(a) and 10(b), the discharge port 8 faces the eyeball 101 and is oriented horizontally. The striking member 3 rotates around the shaft portion 25 against the urging force, and the striking portion 51 separates from the tube member 6 .

At this time, the shape of the tube member 6 is restored as shown in FIGS. 11(a) and 11(b) and becomes cylindrical, and the chemical solution 100 is automatically replenished from the chemical solution reservoir 5 into the tube member 6 by capillary action. be done.

Then, as shown in FIGS. 10(b) and 10(c), when the user releases the operating portion 52, the striking member 3 rotates about the shaft portion 25 due to the biasing force of the biasing member 7. The tube member 6 is hit. As a result, the tube member 6 is elastically deformed as shown in FIGS.

At this time, the chemical solution 100 ejected from the ejection port 8 is a small amount of the chemical solution 100 and is ejected substantially linearly within a range of at least more than 0 cm and not more than 0.5 cm from the ejection port 8 .
In addition, the discharge amount of the chemical solution 100 from the discharge port 8 at this time is preferably 0.01 μL or more and 100 μL or less, more preferably 0.1 μL or more and 10 μL or less, and 0.1 μL or more and 7 μL or less. is particularly preferred.
Within this range, excessive administration of the liquid medicine 100 can be prevented, and problems caused by excessive administration and side effects caused by preservatives and the like can be reduced.
A method for adjusting the discharge amount of the liquid medicine 100 from the discharge port 8 is not particularly limited, but for example, the length D of the striking portion of the striking portion 51 may be changed, or the inner diameter of the tube member 6 may be changed. can be adjusted with

Next, the drug solution 100 that can be suitably used in the dispensing device 1 will be described.

The drug solution 100 is not particularly limited as long as it is used as an ophthalmic drug.
The drug solution 100 is preferably an oil-based formulation, an aqueous formulation, a suspension formulation, or an emulsified formulation, and more preferably an oil-based formulation.
A solvent that can be used as a base for the chemical solution 100 is not particularly limited as long as it is liquid in a temperature range from a cool place to room temperature. Examples of solvents include water, ethyl alcohol, ethylene glycol, polyethylene glycols, propylene glycol, medium-chain triglycerides, glycerin, vegetable oils, animal oils, mineral oils, perfluorocarbons, and mixtures thereof.
Examples of drugs in the drug solution 100 include anti-inflammatory agents such as dipotassium glycyrrhizinate, epsilon aminocaproic acid, allantoin, berberine chloride and berberine sulfate, antihistamines such as diphenhydramine hydrochloride and chlorpheniramine maleate, sodium flavin adenine dinucleotide, and cyanocobalamin. , retinols, pyridoxine hydrochloride, panthenol, sodium pantothenate, sodium chondroitin sulfate and other corneal therapeutic agents, decongestants such as epinephrine, ephedrine hydrochloride, tetrahydrozoline hydrochloride, naphazoline hydrochloride, phenylephrine hydrochloride, dl-methylephedrine hydrochloride, ofloxacin, Antibacterial agents such as levofloxacin, tosufloxacin, gatifloxacin, gentamicin, sulfamethoxazole and sulfisoxazole; β-lactam antibiotics such as cephalexin, imipenem and meropenem; antifungal agents such as amphotericin B, ketoconazole and fluconazole cooling agents such as menthol, borneol, and camphor; timolol maleate, pilocarpine hydrochloride, carteolol, glaucoma and ocular hypertension drugs such as timolol maleate, tafluprost, travoprost, and lipasudil; Anticataract agents such as sodium phosphate, antibiotics such as chloramphenicol, colistin, erythromycin, etc., immunosuppressants such as rapamycin, tacrolimus, cyclosporine, etc., adrenal cortex such as hydrocortisone acetate, prednisolone acetate, dexamethasone, triamcinolone acetonide, fluorometholone, etc. Hormones, carbonic anhydrase inhibitors such as brinzolamide, dorzolamide, and methazolamide, α2 blockers such as brimonidine, α1 blockers such as bunazosin, tocopherols, antioxidants such as vitamin C, hyaluronic acid, chondroitin sulfate, gefarnate, Mucous membrane repair agents (dry eye treatment agents) such as vitamin U and rebamipide, local anesthetics such as lidocaine hydrochloride and dibucaine hydrochloride, test agents such as fluorescein, rose bengal, cyclopentolate and tropicamide, protein preparations, antibody preparations, Examples include nucleic acid preparations.

Although the viscosity of the chemical liquid 100 is not particularly limited, it is preferably 10000 cps or less, more preferably 1000 cps or less, and still more preferably 300 cps or less.

According to the drug administration device 1 of the first embodiment, since the liquid medicine 100 is discharged from the discharge port 8 by operating the operation part 52, the patient does not need to face upward, and the liquid medicine can be discharged from all directions without depending on gravity. 100 can be administered. Therefore, even elderly people, rheumatism patients, patients with poor grip strength, and other people who have difficulty administering drugs can accurately administer a prescribed amount of the medicinal solution 100 to the surface of the eyeball 101 of the patient. As a result, convenience for patients can be improved, excessive administration of the medical solution 100 can be prevented, and side effects such as preservatives can be reduced.
In addition, according to the drug administration device 1 of the first embodiment, since the patient does not need to face upward, the drug solution 100 can be administered while the patient is sitting when administering the test drug in an ophthalmologic examination room, which is convenient. can be improved.

According to the dispensing device 1 of the first embodiment, the amount of liquid medicine to be ejected (eg, 0.001 to 7 μL) is much smaller than the amount of droplets (25 to 50 μL) produced by drip administration of conventional eye drops. Therefore, the medicinal solution 100 ejected onto the surface of the eyeball 101 is very small, and there is no fear that the medicinal solution 100 will flow out of the eye, so that all of the medicinal solution can be effectively utilized.
In addition, according to the drug administration device 1 of the first embodiment, it is possible to administer a very small amount of the drug solution 100 compared to conventional drip administration from an eyedropper, and the effect of the drug solution 100 on the living body is reduced. The degree of freedom in designing the liquid medicine 100 is high, such as being able to have a range, a wide osmotic pressure range, and a wide viscosity range. In addition, it is possible to administer the oil-based liquid medicine 100 without discomfort.
Furthermore, according to the drug administration device 1 of the first embodiment, the medicinal solution 100 administered to the surface of the eyeball 101 can be made into minute droplets, so that the patient is prevented from feeling discomfort or irritation in the eyeball 101. can.

According to the drug administration device 1 of the first embodiment, by operating the operation part 52, part of the tube member 6 is hit by the hitting part 51, and part of the drug solution 100 in the tube member 6 is discharged. 8 is pushed out and discharged. Therefore, a very small amount of the chemical solution 100 can be discharged in a straight line.

According to the drug administration device 1 of the first embodiment, the tube member 6 feeds the liquid from the liquid medicine reservoir 5 toward the ejection port 8 side by capillary action. Therefore, the medical solution 100 can be automatically and easily replenished into the tube member 6 .

According to the drug administration device 1 of the first embodiment, since the entire area of the tube member 6 constitutes an elastic region, there is no need to combine a plurality of types of elastic materials for the tube member 6, and manufacture is easy.

According to the drug administration device 1 of the first embodiment, by operating the operation portion 52, the striking portion 51 changes its posture against the biasing force from the biasing member 7, and is directed toward the tube member 6 by the biasing force. Then, the striking part 51 strikes. That is, since the urging force of the urging member 7 can be applied, the liquid medicine 100 can be more accurately ejected from the ejection port 8 .

According to the drug administration device 1 of the first embodiment, by operating the operation part 52 with the ejection port 8 oriented in the horizontal direction, the liquid medicine 100 is substantially in a range of at least more than 0 cm and 0.5 cm or less from the ejection port 8. It is discharged in a straight line. Therefore, even when a third party such as a doctor, a nurse, or a caregiver administers the drug, the drug can be administered easily.

According to the drug administration device 1 of the first embodiment, the projecting portion 59 is provided on the upstream side of the hitting portion 51 in the flow direction of the drug solution 100 of the tube member 6 by capillary action. Therefore, when the tube member 6 is hit by the hitting part 51 , the convex part 59 can block the movement of the liquid medicine 100 toward the side of the liquid medicine storage part 5 , and the liquid medicine 100 can be more accurately discharged from the discharge port 8 . can.

Next, a drug administration device 200 according to a second embodiment of the invention will be described. In addition, about the same structure as the injection device 1 of 1st Embodiment, the same code|symbol is attached|subjected and description is abbreviate|omitted. The same shall apply hereinafter.

A drug administration device 200 according to the second embodiment of the present invention includes a case member 2, an operation unit 203, a liquid medicine reservoir 5, a tube member 6, and a discharge port 8, as shown in FIG.

The operating unit 203 includes a first operating portion 210, a second operating portion 211, a first engaging portion 212, a second engaging portion 213, a first biasing member 215, and a second biasing member 216. I have.
The first operating portion 210 is a portion that is pressed by the user, and is a portion that presses the first engaging portion 212 in accordance with the user's pressing operation.
The second operation portion 211 is a portion that is pressed by the user, and is a portion that presses the second engaging portion 213 in accordance with the user's pressing operation.
As shown in FIG. 12, the first engaging portion 212 is a plate-like or rod-like portion extending in a predetermined direction, and is composed of a first shaft portion 217, a first extension portion 218, and a second extension portion 219. ing.
The first shaft portion 217 is a portion that is fixed to the main body wall portions 20 and 30 of the case member 2 and pivotally supports an intermediate portion in the longitudinal direction of the first engaging portion 212 .
The first extending portion 218 is located on one end side in the longitudinal direction with respect to the first shaft portion 217 , and includes a striking portion 51 that strikes the tube member 6 .
The second extending portion 219 is located on the other end side in the longitudinal direction with respect to the first shaft portion 217 , and includes a pressed portion 221 that is pressed by the first operating portion 210 .
The pressed portion 221 is also a portion to be pressed by the first biasing member 215 in a direction opposite to the pressing direction from the first operating portion 210 .

As shown in FIG. 12, the second engaging portion 213 is a plate-like or rod-like portion extending in a predetermined direction, and includes a pressed portion 231, an engaging piece 232, a connecting portion 233, and a second shaft portion 235. It has
The pressed portion 231 is a portion that is pressed by the second operating portion 211 and is a portion that is biased by the second biasing member 216 in the direction opposite to the pressing direction of the second operating portion 211 . .
The engaging piece 232 is a portion that engages with the first engaging portion 212 and is rotatably connected to the pressed portion 231 via a connecting portion 233 with directionality.
The connecting portion 233 is specifically a hinge, and connects the surface of the pressed portion 231 on the side of the second operating portion 211 and the surface of the engaging piece 232 on the side of the second operating portion 211 . That is, the connecting portion 233 allows the engagement piece 232 to move toward the second operating portion 211 with respect to the pressed portion 231, and restricts the movement of the engagement piece 232 toward the tube member 6 with respect to the pressed portion 231. ing.
Note that the connecting portion 233 may be a pin.
The second shaft portion 235 is fixed to the case member 2 and pivotally supports one end (outer end) of the pressed portion 231 in the longitudinal direction.

Next, the positional relationship of each member of the dispensing device 200 when the first operating section 210 and the second operating section 211 are not operated will be described.

A portion of the tube member 6 is inserted into the drug solution storage section 5 , and the tip portion is immersed in the drug solution in the drug solution storage section 5 .
The first operating portion 210 and the second operating portion 211 protrude from the side portion 42 of the case member 2 and are in a state capable of being pressed.
The intermediate portion of the first engaging portion 212 is rotatably supported by the first shaft portion 217 .
The first engaging portion 212 is arranged between the first biasing member 215 and the first operating portion 210, and extends from the first biasing member 215 upward (toward the first operating portion 210). energized.
The hitting part 51 receives the biasing force of the first biasing member 215 and presses a part of the tube member 6 toward the hit part 62 side of the liquid medicine storage part 5 .

The second engaging portion 213 is rotatably supported at its outer end by a second shaft portion 235 . That is, the second engaging portion 213 is cantilevered by the second shaft portion 235 .
The second engaging portion 213 is disposed between the second biasing member 216 and the second operating portion 211, and extends from the second biasing member 216 upward (toward the second operating portion 211). energized.
The second engaging portion 213 has an engaging piece 232 arranged in a row with the pressed portion 231 via a connecting portion 233, and has a plate-like or rod-like shape.
The second shaft portion 235 is positioned above the first shaft portion 217 (on the side portion 42 side).

Next, a drug administration method for administration to a user using the drug administration device 200 will be described.

As shown in FIG. 13A , when the user presses the first operating portion 210 , the first engaging portion 212 moves around the first shaft portion 217 against the biasing force of the first biasing member 215 . It rotates and comes into contact with the engaging piece 232 of the second engaging portion 213 .
When the first operating portion 210 is further pressed, the engaging piece 232 rotates about the connecting portion 233 with respect to the pressed portion 231 as shown in FIG. The tip portion is located above the end portion of the second engaging portion 213 . Thereafter, as shown in FIG. 13C, the first engaging portion 212 rotates in the opposite direction around the first shaft portion 217 due to gravity, and when the user stops pressing the first operating portion 210, the first engaging portion 212 rotates in the opposite direction. The first engaging portion 212 and the second engaging portion 213 are engaged.

At this time, since the hitting portion 51 is separated from the tube member 6 as the user presses the first operation portion 210, the chemical solution 100 is introduced into the tube member 6 by capillary action, and the chemical solution is introduced into the tube member 6. 100 is filled.

Subsequently, when the second operating portion 211 is pressed, the second engaging portion 213 is pressed by the second operating portion 211 to push against the biasing force of the second biasing member 216, as shown in FIG. 14(d). The second engaging portion 213 rotates around the second shaft portion 235 . 14(e), when the engagement between the first engaging portion 212 and the second engaging portion 213 is released, the first urging member 215 pushes the first engaging portion 212 toward the first shaft portion 217 as a center, and the striking part 51 strikes a part of the tube member 6 as shown in FIG. 14(f). Then, the chemical solution 100 in the tube member 6 is linearly discharged from the discharge port 8 by the impact force.

Next, a drug administration device 300 according to a third embodiment of the invention will be described.

A drug administration device 300 according to the third embodiment of the present invention includes a case member 2, an operation unit 303, a liquid medicine reservoir 5, a tube member 6, and a discharge port 8, as shown in FIG.

The operating unit 303 includes an operating portion 310 , a first engaging portion 312 , a second engaging portion 313 , a first biasing member 215 and a second biasing member 216 .
The operation portion 310 is a portion that is pressed by the user, and is a portion that presses the first engaging portion 312 in accordance with the user's pressing operation.

The first engaging portion 312 is a plate-like or rod-like portion extending in a predetermined direction, and includes a pressed portion 321 and a first shaft portion 322 .
The pressed portion 321 is a portion that is pressed by the operation portion 310 , and is a portion that is biased by the first biasing member 215 in a direction opposite to the pressing direction of the operation portion 310 .
The first shaft portion 322 is fixed to the case member 2 and pivotally supports one end (outer end) of the pressed portion 321 in the longitudinal direction.

The second engaging portion 313 is a plate-like or rod-like portion extending in a predetermined direction, and is composed of a second shaft portion 335 , a first extending portion 336 and a second extending portion 337 .
The second shaft portion 335 is a portion that is fixed to the case member 2 and pivotally supports an intermediate portion of the second engaging portion 313 in the longitudinal direction.
The first extending portion 336 is located on one end side in the longitudinal direction with respect to the second shaft portion 335 , and includes a striking portion 51 that strikes the tube member 6 .

The second extending portion 337 is located on the other end side in the longitudinal direction with respect to the second shaft portion 335 , and is composed of a body portion 341 , an engaging piece 342 and a connecting portion 343 .
The body portion 341 is a portion that extends continuously with the first extending portion 336 .
The engaging piece 342 is a part that engages with the first engaging portion 312 , and is rotatably connected to the main body portion 341 via a connecting portion 343 with directionality.
The connecting portion 343 is specifically a hinge, and connects the surface of the body portion 341 on the operating portion 310 side and the surface of the engaging piece 342 on the operating portion 310 side. Note that the connecting portion 343 may be a pin.

Next, the positional relationship of each member of the dispensing device 300 when the operation unit 310 is not operated will be described.

A portion of the tube member 6 is inserted into the drug solution storage section 5 , and the tip portion is immersed in the drug solution in the drug solution storage section 5 .
As shown in FIG. 16A, the operating portion 310 protrudes from the side portion 42 of the case member 2 and is in a state in which it can be pressed.
One end of the first engaging portion 312 is rotatably supported by the first shaft portion 322 . That is, the first engaging portion 312 is supported by the first shaft portion 322 in a cantilevered manner.
The first engaging portion 312 is arranged between the first biasing member 215 and the operating portion 310 and is biased upward from the first biasing member 215 .

The intermediate portion of the second engaging portion 313 is rotatably supported by the second shaft portion 335 .
The second engaging portion 313 is arranged between the liquid medicine storage portion 5 and the second biasing member 216 at a position overlapping the tube member 6 in the vertical direction.
The second engaging portion 313 presses a portion of the tube member 6 toward the liquid medicine storage portion 5 by receiving the biasing force of the second biasing member 216 .
In the second engaging portion 313 , the engaging piece 342 is aligned with the main body portion 341 via the connecting portion 343 .
The second shaft portion 335 is located below the first shaft portion 322 (on the side portion 44 side).

Next, the operation of administering to the user using the drug administration device 300 will be described.

When the user presses the operating portion 310, the first engaging portion 312 is pressed by the operating portion 310, and the biasing force of the first biasing member 215 acts as shown in FIGS. Conversely, the first engaging portion 312 rotates around the first shaft portion 322 . When the first engaging portion 312 rotates, the inner end portion of the second engaging portion 313 is pressed downward, and the second engaging portion 313 rotates about the second shaft portion 335 against the biasing force of the second biasing member 216 . It rotates in a direction away from the 1 engaging portion 312 .

At this time, since the hitting part 51 is separated from the tube member 6 by the user's pressing operation, the chemical solution 100 is introduced into the tube member 6 by capillary action, and the tube member 6 is filled with the chemical solution 100 .

Then, as shown in FIGS. 16(b) and 16(c), when the first engaging portion 312 and the second engaging portion 313 rotate together and separate from each other to release the engagement, the second engaging portion 312 and the second engaging portion 313 rotate. The biasing force of the biasing member 216 causes the second engaging portion 313 to rotate, and the impacting portion 51 impacts a part of the tube member 6 . Then, the chemical solution 100 inside the tube member 6 is discharged from the discharge port 8 .

17(d) and 17(e), when the user stops pressing the operating portion 310, the first engaging portion 312 is reversed by the biasing force of the first biasing member 215, and engaged. Press the piece 342 . When the engaging piece 342 is pressed, the engaging piece 342 rotates through the connecting portion 343 to release the pressing force of the first engaging portion 312 , and the first engaging portion 312 moves toward the second engaging portion 313 . located above.

According to the dispensing device 300 of the third embodiment, the medicinal solution 100 can be discharged from the discharge port 8 simply by pressing the operation part 310, and the operability is excellent.

Next, a drug administration device 500 according to a fourth embodiment of the invention will be described. It should be noted that the dispensing device 500 can also take any posture as in the above embodiment, and can administer the liquid medicine 100 from any direction such as upward, downward, or sideways. In order to achieve this, the description will be made on the basis of a state in which the liquid medicine 100 can be ejected in the horizontal direction and the operation member 512 is on the upper side.

As shown in FIGS. 18 and 19, the drug administration device 500 of the fourth embodiment includes a body portion 501 and a liquid medicine cartridge 502 (liquid cartridge). ing.
The body portion 501 includes a case member 510, a striking member 511, and an operating member 512, as shown in FIG.
The case member 510 is composed of a pair of case portions 520 and 521 as shown in FIG.
As can be seen from FIGS. 19, 20, and 22, the case member 510 includes a front wall portion 530 (530a, 530b), a rear wall portion 531 (531a, 531b), a top wall portion 532 (532a, 532b), Bottom wall portions 533 (533a, 533b), side wall portions 535 (535a, 535b), front-side guide wall portions 536 (536a, 536b), and rear-side guide wall portions 537 (537a, 537b) are fixed in position. It has a portion 538 (538a, 538b), a fixing portion 540 for striking, and a fitting portion 541 (541a, 541b).
The case member 510 also has an internal space 542 surrounded by the walls 530-535.

As shown in FIGS. 20 and 21, the front wall portion 530 has a chemical solution passage hole 550 (liquid passage hole) that penetrates from the outside toward the internal space 542 in the front-rear direction, and a case-side regulation groove 551 that extends in the vertical direction. I have.
The chemical solution passage hole 550 is a hole through which the chemical solution discharged from the ejection port 8 of the chemical solution cartridge 502 passes.
The case-side regulating groove 551 is a groove that regulates the moving direction of the closing portion 583 of the operating member 512 that closes the discharge port 8 of the liquid cartridge 502, and its depth is longer than the length of the closing portion 583 of the operating member 512. .

As shown in FIG. 19, the rear wall portion 531 has a mounting portion 555 to which the liquid cartridge 502 can be mounted.
The mounting portion 555 is a mounting hole extending from the outside toward the internal space 542 as shown in FIG.
The mounting portion 555 is provided with a regulation groove 556 that regulates the direction of the liquid cartridge 502 as shown in FIGS. 19 and 22 .

The top surface wall portion 532 has a communication hole 560 that penetrates vertically from the outside toward the internal space 542 and communicates with the internal space 542 .
The communication hole 560 is an insertion hole into which the operating-side pressing portion 585 and the operating-side engaging portion 586 of the operating member 512 can be inserted, and is also continuous with the restricting groove 556 of the mounting portion 555 .

A bottom wall portion 533b of one case portion 521 is provided with a guiding portion 561 as shown in FIG.
The guide portion 561 is a triangular plate-like portion that guides the body plate portion 595 of the operation member 512 toward the side wall portion 535b.
The guiding portion 561 of the present embodiment is composed of a plurality of right-angled triangular plate-shaped pieces aligned in the front-rear direction, and slopes of the respective plate-shaped pieces form inclined portions 562 on the side of the side wall portion 535b. there is

As shown in FIG. 20, the side wall portion 535 has slide grooves 565 and 566 extending from the upper end toward the lower end in the vertical direction and locking grooves 567 and 568 on the outer surface.
The slide grooves 565 and 566 are regulation grooves that regulate the sliding direction of the leg portions 588 and 589 of the operating member 512 in the vertical direction.
The locking grooves 567 and 568 are portions that extend vertically and engage with the locking claws 590 and 591 of the side wall portions 581 and 582 to prevent the operation member 512 from separating from the case member 510 .
In other words, the locking grooves 567 and 568 form locking surfaces on which the inner wall portions positioned at the upper ends of the locking grooves 567 and 568 lock the locking claws 590 and 591 of the side wall portions 581 and 582 .

The guide wall portions 536 and 537 are portions that guide the movement direction of the operation member 512 in the vertical direction, and are wall portions that protrude upward from the top wall portion 532 .
The position fixing part 538 is a part that fixes the distance and position between the ejection port 8 and the user's eyeball 101 .
The striking fixing portion 540 is a portion that holds the connecting portion 572 of the striking member 511 .

The fitting portions 541 (541a, 541b) are portions that fit together to fix the case portions 520, 521 together.
Of the case portions 520 and 521, the fitting portion 541a of one case portion 520 is a concave portion as shown in FIG. 20, and the fitting portion 541b of the other case portion 521 is a convex portion as shown in FIG.

The striking member 511 includes a striking portion 570, an elastic portion 571, and a connecting portion 572, as shown in FIG.
The striking portion 570 includes a flat portion 58 , a convex portion 59 projecting from the flat portion 58 , and an engaging portion 575 .
The engaging portion 575 is a portion that engages with the locking surface 597 of the operating member 512 when no load is applied to the operating member 512 .

The elastic portion 571 is an elastically deformable member, specifically a plate spring.
The elastic portion 571 is cantilevered by the case member 510 via the connection portion 572 and extends from the connection portion 572 in the same direction as the striking portion 570 (forward direction).
The connecting portion 572 is fixed to the striking fixing portion 540 and connected to the case member 510 .

The operating member 512 includes an operating surface portion 580, side wall portions 581 and 582, a closing portion 583, an operating side pressing portion 585, and an operating side engaging portion 586, as shown in FIGS.
The operation surface portion 580 is a portion that is pressed by the user, and is a plate-like portion that constitutes the top surface of the dispensing device 500 .
As shown in FIG. 24, the side walls 581 and 582 are wall portions hanging downward from the operation surface portion 580 and include a body portion 587 and leg portions 588 and 589 .
The main body portion 587 is a plate-like portion extending in the front-rear direction, and has locking claws 590 and 591 at or near the lower end portion for locking the separation of the operating member 512 from the case member 510 .
The leg portions 588 and 589 are protruding portions protruding downward from the lower end portion of the main body portion 587 .

The blocking portion 583 is a portion that blocks the discharge port 8 of the liquid cartridge 502 as shown in FIG. 24 .
The closing portion 583 is a plate-like body extending downward from the operation surface portion 580 and has an operation side through hole 592 penetrating in the thickness direction.
The operation-side through-hole 592 is an open hole that opens the discharge port 8 of the liquid cartridge 502 when the operation member 512 is operated.
The operation-side pressing portion 585 is a projecting portion that extends downward from the operation surface portion 580, and is a portion that presses the elastic portion 571 of the striking member 511 at the end portion in the extending direction.

The operation-side engaging portion 586 includes a body plate portion 595 and a locking portion 596 as shown in FIG.
The body plate portion 595 is a projecting portion that extends downward from the operation surface portion 580, and is a portion that presses the guiding portion 561 of the case portion 521 at the end portion in the extending direction.
The locking portion 596 is provided at an intermediate portion in the extending direction of the body plate portion 595 and engages with the engaging portion 575 of the striking portion 570 of the striking member 511 to prevent the upward movement of the striking member 511. This is the portion to be locked.
The locking portion 596 is a projection projecting in a direction intersecting the extending direction of the main body plate portion 595 , and has a locking surface 597 and an inclined surface 598 .
The locking surface 597 is a surface that contacts and locks the engaging portion 575 of the striking portion 570 facing downward, and is a vertical surface that rises perpendicularly to the inner surface of the main body plate portion 595 .
The inclined surface 598 is a surface inclined at an acute angle with respect to the inner surface of the body plate portion 595 .

The liquid medicine cartridge 502 is composed of a liquid medicine reservoir 601 and a tube member 6 as shown in FIG.
The liquid medicine storage part 601 is a rectangular parallelepiped member having a storage space 65 inside and extending in the insertion direction of the liquid medicine cartridge 502 .
The drug solution reservoir 601 has a notch 602 extending from the distal end to the proximal end in the direction of insertion, and the tube member 6 is arranged in the notch 602 .
On the inner surface of the notch 602, there is the struck portion 62, and a flat portion 68 and a concave portion 69 are formed.
As shown in FIG. 19, the liquid medicine storage part 601 has a protruding streak part 603 extending from the proximal end to the distal end in the direction of insertion.

Next, the positional relationship of each member of the dispensing device 500 in a state in which the operation member 512 is not operated, that is, in a no-load state will be described.

As shown in FIG. 21, the dispensing device 500 has a striking member 511 and a liquid medicine cartridge 502 arranged inside a case member 510 , and an operation member 512 covering the case member 510 on the outside.
As shown in FIG. 20, the case member 510 is connected so that the side wall portions 535a and 535b of the case portions 520 and 521 are on the outside.
The fitting portion 541a of the case portion 520 is fitted with the fitting portion 541b of the case portion 521 inserted therein.
As shown in FIG. 21, the impacting member 511 has a connecting portion 572 fixed to the impacting fixing portion 540 of the case member 510, and the impacting portion 570 and the elastic portion 571 are supported by the case member 510 in a cantilever manner. It is That is, the base end portions of the striking portion 570 and the elastic portion 571 are fixed to the striking fixing portion 540, and the distal end portions are free ends.
As shown in FIGS. 18 and 19, the operation member 512 has an operation surface portion 580 that is flush with the leading end surfaces of the guide walls 536 and 537 of the case member 510 in the protruding direction.
The operation member 512 has a blocking portion 583 inserted into the case-side regulation groove 551 of the case member 510 to block the chemical passage hole 550 . In other words, the dispensing device 500 is in a closed state in which the liquid medicine passage hole 550 is closed by the closing portion 583 .
The liquid cartridge 502 is attached to the attachment portion 555 , and the protrusion 603 is inserted into the regulation groove 556 of the case member 510 .

Next, a drug administration method for administration to a user using the drug administration device 500 will be described.

First, as can be read from FIG. 19, the chemical liquid cartridge 502 containing the desired chemical liquid is inserted into the mounting portion 555 of the main body 501 .

At this time, the liquid cartridge 502 moves linearly along the regulation groove 556 of the mounting portion 555 and is arranged so that the tube member 6 faces the striking portion 570 .
At this time, since the dispensing device 500 is in the closed state as shown in FIG. do.

Subsequently, as shown in FIGS. 26A and 26B, when the user presses the operation surface portion 580 of the operation member 512 with his/her finger, the operation side pressing portion 585 of the operation member 512 presses the elastic portion 571. Then, the locking surface 597 of the locking portion 596 of the operating-side engaging portion 586 presses the engaging portion 575 of the impacting portion 570 , and the elastic portion 571 and the impacting portion 570 rotate about the connecting portion 572 .

The operating surface portion 580 of the operating member 512 is pressed, and as shown in FIG. When the portion 570 rotates further, the main body plate portion 595 moves outward along the inclined portion 562 of the guide portion 561, and the engagement between the locking surface 597 of the locking portion 596 and the engaging portion 575 of the striking portion 570 is disengaged. be released.

At this time, the operation-side through hole 592 is aligned with the liquid medicine passage hole 550 in a straight line, and the liquid medicine passage hole 550 is opened, resulting in the open posture shown in FIG. 18(b).

When the engagement between the locking surface 597 of the locking portion 596 and the engaging portion 575 of the striking portion 570 is released, the striking portion 570 pushes the connection portion 572 by its own restoring force as shown in FIG. 27(c). , and the hitting part 570 hits a part of the tube member 6 .
Then, the medicinal solution 100 in the tube member 6 is linearly expelled from the ejection port 8 by the impact force, passes through the medicinal solution passage hole 550 and the operation-side through hole 592, and reaches the eyeball 101 of the user.

At this time, a centrifugal force around the connecting portion 572 acts on the hitting portion 570, and the hitting portion 570 exceeds the height of the connecting portion 572 and hits the elastic region of the tube member 6 by inertia.

After hitting the tube member 6, the hitting part 570 tries to return to the position in the closed state by the reverse restoring force as shown in FIG. 27(d).

When the user stops pressing the operation surface portion 580, the operation member 512 moves upward due to the restoring force of the elastic portion 571 as shown in FIGS. , the engaging portion 575 of the striking portion 570 moves along the inclined surface 598, and the engaging portion 575 of the striking portion 570 engages with the locking surface 597 over the inclined surface 598. As shown in FIG. As the operation member 512 moves upward, the closing portion 583 moves along the case-side restricting groove 551, and the chemical passage hole 550 shown in FIG. back to

According to the drug administration device 500 of the present embodiment, the drug solution cartridge 502 is detachable from the main body 501, so that the drug solution cartridge 502 can be easily replaced when the drug solution runs out or when a different drug solution is to be applied.

According to the drug administration device 500 of the present embodiment, when the pressing operation is not performed, the closing portion 583 closes the drug solution passage hole 550, and when the pressing operation is performed, the closing portion 583 moves along with the pressing operation. to automatically open the chemical solution passage hole 550 . That is, when the pressing operation is not performed, the ejection port 8 of the tube member 6 is always protected by the blocking portion 583, so that the ejection port 8 is closed except when the liquid medicine cartridge 502 is replaced or when eye drops are applied. It is not exposed to the outside and the discharge port 8 is less likely to be contaminated.

According to the drug administration device 500 of the present embodiment, the pressing operation causes the striking part 570 to elastically deform, and the restoring force causes the striking part 570 to be at least part of the elastic region higher than the connecting part 572 . hit the That is, like a pendulum, the striking part 570 strikes the tube member 6 due to the restoring force and inertial force of the striking part 570, so there is no need to provide an urging member for striking, and the cost can be reduced. .

Next, a drug administration device 700 according to a fifth embodiment of the present invention will be described.

As shown in FIGS. 29 and 30, a drug dispensing device 700 according to the fifth embodiment has a plurality of liquid medicine cartridges 502a and 502b that can be individually attached to and detached from a mounting portion 555 of a main body portion 501. FIG.
In the drug administration device 700, similarly to the drug administration device 500 of the fourth embodiment, the discharge ports 8, 8 of the drug solution cartridges 502a, 502b are blocked by the blocking portion 583 in the closed state. The liquid medicine cartridges 502a and 502b are changed to the open state, and the discharge ports 8 and 8 of the liquid chemical cartridges 502a and 502b are opened so as to overlap the operating side through holes 592, and the liquid medicine of the liquid chemical cartridges 502a and 502b can be simultaneously discharged from the discharge ports 8 and 8. Become.

According to the drug administration device 700 of the fifth embodiment, since a plurality of drug solution cartridges 502a and 502b can be attached to the main body 501, different types of drug solutions can be administered at the same time. can relieve the patient from

According to the dispensing device 700 of the fifth embodiment, the liquid medicine cartridges 502a and 502b can be replaced individually, so the liquid medicine in the liquid medicine cartridges 502a and 502b can be used to the end.

In the above-described embodiment, the tube member 6 has a uniform inner diameter from the liquid medicine reservoir 5 to the discharge port 8, but the present invention is not limited to this. A narrowed portion may be provided in a part of the tube member 6 between the inside of the liquid medicine reservoir 5 and the discharge port 8 . For example, an orifice may be provided at the end of the impacted portion of the tube member 6 on the discharge port 8 side. By doing so, the discharge distance of the chemical liquid 100 can be improved.

In the above-described embodiment, the hit portion 62 is provided with the concave portion 69 and the hitting portion 51 is provided with the convex portion 59, but the present invention is not limited to this. As shown in FIG. 31(a), the hit part 62 may be provided with a projection 59 and the hitting part 51 may be provided with a recess 69. Alternatively, as shown in FIG. 400 may be provided.
Further, the projecting portion 59 and the recessed portion 69 may not be provided on the hit portion 62 and the hitting portion 51 . That is, the hit portion 62 and the hit portion 51 may be composed of the flat portion 68 and the flat portion 58 alone.

In the above-described embodiment, the cross-sectional shape of the tube member 6 is circular, but the present invention is not limited to this. The cross-sectional shape of the tube member 6 may be triangular, polygonal such as quadrangular, pentagonal, or hexagonal, or may be flat, elliptical, or oval.

In the above-described embodiment, the tube member 6 has a uniform wall thickness, but the present invention is not limited to this. Partially thin-walled portions may be present. For example, the impacted portion of the tube member 6 may be thicker than the other portions.

In the above-described embodiment, the entire tube member 6 is made of an elastic material and the entire area is an elastic region, but the present invention is not limited to this. At least a portion of the tube member 6 in the longitudinal direction, for example, only the region of the tube member 6 that is hit by the hitting portion 51 or only the vicinity of the region that is hit may be the elastic region.

Although the tube member 6 is made of one elastic material in the above-described embodiment, the present invention is not limited to this. As shown in FIG. 32, the tube member 6 may have a two-layer structure of an elastic layer 420 made of an elastic material and a hard layer 421 made of a hard material, or may have three or more layers. . That is, the tube member 6 may have a multilayer structure. In this case, it is preferable that the elastic layer 420 is exposed as an elastic region at least in the portion 85 to be pressed by the striking portion 51 .

In the above-described embodiment, the striking member 3 changes its posture against the biasing force from the biasing member 7, and uses the reaction force to strike the striking portion 51, but the present invention is directed to this. It is not limited. The striking member 3 may move against the urging force from the urging member 7 and strike with the striking portion 51 using the reaction force.

In the above-described embodiments, the case where the dispensing device 1, 200, 300, 500, 700 is used for eye drops has been described, but the present invention is not limited to this. The drug administration device 1, 200, 300, 500, 700 may be used for nasal, ear, oral and transdermal administration.

In the above-described embodiment, the storage space 65 of the drug solution storage unit 5 extends horizontally when the discharge port 8 of the dispensing device 1 faces the horizontal direction, but the present invention is not limited to this. For example, as shown in FIG. 33, the storage space 65 of the drug solution storage unit 5 may extend vertically in the posture in which the ejection port 8 of the dispensing device 1 faces the horizontal direction. In this case, it is preferable that part or all of the bottom portion of the liquid medicine reservoir 5 is inclined downward toward the tube member 6 and provided with an introduction part 450 that guides the liquid medicine 100 to the tube member 6 .

In the first to third embodiments described above, the liquid medicine unit 4 is not removable from the case member 2, but the present invention is not limited to this. The liquid medicine unit 4 may be detachable from the case member 2 . By doing so, the used chemical liquid unit 4 can be replaced with a new chemical liquid unit 4 as in the cartridge system. Therefore, members other than the liquid medicine unit 4 can be reused.

The dispensing device 1 of the embodiment described above may be provided with a protective cover for protecting the discharge port 8 and the tube member 6, if necessary.

The dispensing device 1 of the first to third embodiments described above may be provided with a fixing jig or the like for fixing the distance and position between the discharge port 8 and the eyeball 101, if necessary.

In the above-described embodiment, the hitting portions 51 and 570 change their postures to hit the tube member 6, but the present invention is not limited to this. The hitting parts 51 and 570 may hit the tube member 6 by moving relative to the tube member 6 .

In the above-described fourth embodiment, by operating the operating member 512, the closing portion 583 blocks the chemical solution passage hole 550, and the closing portion 583 moves relative to the case member 510 to open the chemical solution passage hole 550. However, the present invention is not limited to this. By operating the operating member 512, the closing portion 583 may change its posture with respect to the case member 510 to change from the closed state to the open state.

In the above-described embodiment, the case where the liquid ejection device is used as the dispensing device has been described, but the present invention is not limited to this. The liquid ejection device of the present invention can also be used for other applications. For example, it can be used in place of a liquid dispensing pipette, as an adhesive applicator, as a dripper for aromatic oils, perfumes, etc., as a precision part lubrication device, as a veterinary drug administration device, or as an insecticide ejection device.

As long as the above-described embodiments are within the technical scope of the present invention, each component can be freely replaced or added between the embodiments.

EXAMPLES The present invention will be specifically described below with reference to examples. It should be noted that the present invention is not limited to the following examples, and can be modified as appropriate without changing the gist of the invention.

(Example 1)
A silicon tube having an inner diameter of 0.5 mm and an outer diameter of 0.6 mm was used as the tube member, and the length of the striking portion of the striking portion (the length D of the pressed portion of the tube member) was set to 6 mm. Medium-chain fatty acid triglyceride (specific gravity 0.953 g/cm ³ ) was used as the chemical solution. This is referred to as Example 1.

(Example 2)
Example 2 was prepared in the same manner as in Example 1, except that an orifice with an orifice diameter of 0.15 mm was provided at the discharge port of the tube member.

(Discharge amount test)
Since the liquid medicine is transferred from the liquid medicine reservoir to the tube member by capillary action, the influence on the discharge amount was examined when the discharge interval (administration interval: 1 second, 5 seconds, 10 seconds, 20 seconds) was changed. .
At that time, medium-chain fatty acid triglyceride was used as the chemical liquid, and after measuring the ejection amount as weight using a semi-micro balance, the ejection amount (μL) was calculated from the specific gravity of the chemical liquid (test temperature is room temperature). Specifically, the liquid was ejected 10 times, and the total weight (mg) was measured to calculate the single ejection amount (μL).
Table 1 shows the results.

As shown in Table 1, the discharge amount of Example 1 was 1/80 or less of the discharge amount from a normal eye dropper bottle (approximately 40 μL to 50 μL), which was a sufficiently small amount. In Example 2 with an orifice, ejection resistance was generated by the orifice, so the ejection amount was smaller than in Example 1 without an orifice.
In Examples 1 and 2, as shown in Table 1, the standard deviation of the single-time ejection amount (one-drop amount) was 0.05 or less even when ejection was repeated, and the accuracy was high. Further, in Examples 1 and 2, when the ejection interval during repeated ejection was changed to 1 second, 5 seconds, 10 seconds, and 20 seconds, the ejection amount tended to increase slightly, but it was at a problem level. I didn't.

From the above, it was found that a very small amount of drug solution can be administered quantitatively with high accuracy. It was also found that a very small amount of the chemical solution can be linearly ejected from the trajectory of the chemical solution.

1,200,300,500,700 Dosing device (liquid ejection device)
3,511 striking member 5,601 chemical storage unit (liquid storage unit)
6 tube member 7 urging member 8 discharge port 51, 570 striking part 52, 310 operating part 100 chemical solution 210 first operating part 211 second operating part 215 first urging member 216 second urging member 501 body part 502 chemical solution Cartridge (liquid cartridge)
510 case member 512 operating member (operating portion)
520, 521 case portion 550 chemical passage hole (liquid passage hole)
551 Case-side restriction groove 555 Mounting portion 572 Connection portion 580 Operation surface portion 583 Closing portion

The invention according to claim 1 for solving the above-described problem has a chemical storage portion, an operation portion, and a discharge port, and by operating the operation portion, the chemical in the chemical storage portion is released to the discharge port. A dispensing device that discharges liquid onto the surface of the eyeball from the discharge port, wherein when the operation unit is operated 10 times, the discharge amount per discharge from the discharge port is less than 7 μL, and the standard deviation is 0.05 or less. A dispensing device characterized by:
In the invention according to claim 2, when the operation part is operated 10 times at an interval of 10 seconds or less, the single ejection amount from the ejection port is less than 7 μL, and the standard deviation is 0.05 or less. 2. A dispensing device according to claim 1, wherein
The invention according to claim 3 is the dispensing device according to claim 1 or 2, wherein a single discharge amount from the discharge port is less than 1 μL when the operation part is operated 10 times.
According to a fourth aspect of the present invention, there is provided a main body portion having the operation portion, and a plurality of liquid medicine cartridges that can be individually attached to the main body portion, and the plurality of liquid medicine cartridges includes a liquid medicine storage part and a discharger. Each of the plurality of chemical liquid cartridges has an outlet, and the plurality of chemical liquid cartridges includes a first chemical liquid cartridge and a second chemical liquid cartridge, and by operating the operation unit, the liquid from the ejection port of the first chemical liquid cartridge and the ejection port of the second chemical liquid cartridge 4. The dispensing device according to any one of claims 1 to 3, which is capable of ejecting drug solutions simultaneously.
The invention according to claim 5 is the dispensing device according to claim 4, wherein the first chemical liquid cartridge and the second chemical liquid cartridge can eject different types of liquid medicine.
The invention according to claim 6 is the dispensing device according to any one of claims 1 to 5, which has an ejection mechanism capable of administering the liquid medicine in an upward posture.
According to a seventh aspect of the present invention, when the operating portion is operated with the ejection port facing in the horizontal direction, the chemical liquid is released from the ejection port within a range of at least 0 cm and 0.5 cm or less from the ejection port. Dispensing device according to any one of claims 1 to 6, which dispenses at an angle of 1 degree or less with respect to the horizontal.
An invention related to the present invention is a liquid ejection device having a liquid storage portion, a tube member, a striking portion, a struck portion, and an operation portion, and ejecting liquid from an ejection port, the device comprising: The tube member communicates with the inside of the liquid storage portion at one end thereof, and feeds the liquid from the liquid storage portion toward the ejection port side. There is a deformable elastic region, and by operating the operation portion, the tube member is positioned between the striking portion and the struck portion and on the side of the struck portion, and the state where the tube member is located on the side of the struck portion is changed to the struck portion. The hitting part hits at least a part of the elastic region of the tube member without moving with respect to the hitting part, presses the tube member toward the hit part, and The tube member is sandwiched together with the hitting part, and the liquid in the tube member is pushed out from the discharge port and discharged, and the tube member is elastically deformed by the pressing force of the hitting part. The liquid ejecting apparatus is characterized in that the liquid is replenished from the liquid storage section by capillary action by restoring the shape of the tube member.
An invention related to the present invention is a liquid ejection device that includes a liquid storage portion, a tube member, a striking portion, and an operation portion, and ejects liquid from an ejection port, wherein the tube member includes the liquid. One end of the tube member communicates with the inside of the storage section, and the liquid is fed from the liquid storage section toward the ejection port side. At least a part of the elastic region of the tube member is struck by the striking portion by operating the operation portion, and the liquid in the tube member is pushed out from the ejection port to be ejected. A discharge device.

In the above invention, the elastic region is at least selected from the group consisting of polyethylene, polypropylene, silicone, fluororubber, polytetrafluoroethylene, nylon, polyethylene terephthalate, polybutylene terephthalate, polyethylene naphthalate, natural rubber, and synthetic rubber. It relates to a liquid ejection device made of one elastic material.

The above invention has an urging member that urges the striking portion toward the elastic region, and by operating the operation portion, the striking portion resists the urging force from the urging member. The present invention relates to a liquid ejecting device in which the striking portion is moved or changed in posture by the urging force and the striking portion collides toward the elastic region.

In the above invention, the maximum inner diameter of the elastic region of the tube member is 0.1 mm or more and 2 mm or less, and the amount of liquid discharged from the discharge port when the operation portion is operated once is 0.01 μL. This relates to a liquid ejecting apparatus of 7 μL or less.

The above invention relates to a liquid ejecting apparatus in which the amount of liquid ejected from the ejection port is 0.01 μL or more and 7 μL or less when the operation portion is operated once.
The above invention relates to a liquid ejecting apparatus in which the amount of liquid ejected from the ejection port is less than 1 μL when the operating portion is operated once.
The above invention relates to a liquid ejecting apparatus in which the amount of liquid ejected from the ejection port is 0.625 μL or less when the operating portion is operated once.
The above invention relates to a liquid ejecting apparatus in which the amount of liquid ejected from the ejection port is 0.01 μL or more and 100 μL or less when the operation portion is operated once.

The invention described above relates to the liquid ejecting device, wherein the hit range of the hit part of the tube member is 1 mm or more and 30 mm or less in the longitudinal direction.

In the above invention, when the operation part is operated with the ejection port oriented in the horizontal direction, the liquid is ejected substantially linearly in at least a range of more than 0 cm and 0.5 cm or less from the ejection port. It is related to the liquid ejector which is manufactured .

The above invention has a body portion and a liquid cartridge, wherein the body portion includes the striking portion and the operation portion, the liquid cartridge includes the liquid storage portion and the tube member, and the body It relates to a liquid ejection device that is detachable from a part.

The above invention includes a case portion that accommodates at least a portion of the tube member so as to incorporate the discharge port, and a closing portion that moves or changes its posture relative to the case portion in conjunction with the operation portion. The case portion has a liquid passage hole at a position facing the discharge port, and the closing portion has an operation-side through hole, and the closing portion is opened by operating the operation portion. Between a closed state in which the liquid passage hole is closed and an open state in which the operation-side through-hole is linearly aligned with the liquid passage hole and the liquid passage hole is opened as the closing portion moves or changes its posture. It relates to liquid ejectors that are modifiable.
An invention related to the present invention is a case portion that accommodates at least a part of the tube member so as to incorporate the discharge port, and a case portion that is interlocked with the operation portion to move or change the posture relative to the case portion. The case portion has a liquid passage hole at a position facing the discharge port, and by operating the operating portion, the liquid passage hole is closed by the closing portion. and an open state in which the closing portion moves or changes its attitude to open the liquid passage hole.

The above-described invention is a liquid ejection device that includes a liquid storage portion, a tube member, a striking portion, a struck portion, and an operation portion, and ejects liquid from an ejection port, wherein the tube member is , one end communicates with the inside of the liquid storage part, and the liquid is sent from the liquid storage part toward the ejection port side, and the tube member is elastically deformable at least partially in the longitudinal direction. There is an elastic region, and by operating the operating portion, the tube member is positioned between the hitting portion and the hit portion and is positioned on the side of the hit portion, and the hit portion moves to the above-mentioned position. Without moving relative to the striking part, the striking part strikes at least a part of the elastic region of the tube member, presses the tube member toward the struck part, and causes the struck part to move. The liquid in the tube member is pushed out and discharged from the discharge port, and has a case member and a striking member, wherein the case member is fixed for striking. The operation part has an operation-side engagement part, and the striking member has the striking part and a connection part, and is connected by the striking fixing part of the case member. The elastic region of the tubular member is positioned higher than the connecting portion to operate the operating portion. By doing so, the operating-side engaging portion presses the striking portion, the striking portion is elastically deformed, and the striking portion strikes at least a part of the elastic region by the restoring force. It relates to liquid ejection devices.
An invention related to the present invention has a case member and a striking member having the striking portion, the striking member has a connecting portion, and the connecting portion is held by the case member and cantilevered. The elastic region of the tube member is positioned higher than the connection portion. By operating the operation portion, the impact portion is elastically deformed, and the restoring force of the impact portion causes the impact to occur. In the liquid ejection device, the hitting part hits at least part of the elastic region.

The above-described invention is a dispensing device using the above-described liquid ejecting device, wherein the liquid is a chemical solution.

Claims (1)

A liquid ejection device having a liquid storage part, a tube member, a striking part, and an operation part, and ejecting liquid from an ejection port,
One end of the tube member communicates with the inside of the liquid storage portion, and feeds the liquid from the liquid storage portion toward the ejection port side,
At least a part of the tube member has an elastically deformable elastic region in the longitudinal direction,
By operating the operation part, at least a part of the elastic region of the tube member is hit by the hitting part, and the liquid in the tube member is pushed out from the discharge port and discharged. and a liquid ejecting device.

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