JP2022552003A5 - - Google Patents

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Publication number
JP2022552003A5
JP2022552003A5 JP2022522966A JP2022522966A JP2022552003A5 JP 2022552003 A5 JP2022552003 A5 JP 2022552003A5 JP 2022522966 A JP2022522966 A JP 2022522966A JP 2022522966 A JP2022522966 A JP 2022522966A JP 2022552003 A5 JP2022552003 A5 JP 2022552003A5
Authority
JP
Japan
Prior art keywords
nucleic acid
biologically active
active fragment
exogenous nucleic
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022522966A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022552003A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/056108 external-priority patent/WO2021076983A1/en
Publication of JP2022552003A publication Critical patent/JP2022552003A/ja
Publication of JP2022552003A5 publication Critical patent/JP2022552003A5/ja
Priority to JP2025124068A priority Critical patent/JP2025184866A/ja
Pending legal-status Critical Current

Links

JP2022522966A 2019-10-17 2020-10-16 脊髄損傷およびａｌｓの治療のための機能的ニューロンの再生 Pending JP2022552003A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025124068A JP2025184866A (ja) 2019-10-17 2025-07-24 脊髄損傷およびａｌｓの治療のための機能的ニューロンの再生

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962916713P 2019-10-17 2019-10-17
US62/916,713 2019-10-17
US202063040989P 2020-06-18 2020-06-18
US63/040,989 2020-06-18
PCT/US2020/056108 WO2021076983A1 (en) 2019-10-17 2020-10-16 Regenerating functional neurons for treatment of spinal cord injury and als

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025124068A Division JP2025184866A (ja) 2019-10-17 2025-07-24 脊髄損傷およびａｌｓの治療のための機能的ニューロンの再生

Publications (2)

Publication Number Publication Date
JP2022552003A JP2022552003A (ja) 2022-12-14
JP2022552003A5 true JP2022552003A5 (https=) 2023-10-20

Family

ID=75538363

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022522966A Pending JP2022552003A (ja) 2019-10-17 2020-10-16 脊髄損傷およびａｌｓの治療のための機能的ニューロンの再生
JP2025124068A Pending JP2025184866A (ja) 2019-10-17 2025-07-24 脊髄損傷およびａｌｓの治療のための機能的ニューロンの再生

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025124068A Pending JP2025184866A (ja) 2019-10-17 2025-07-24 脊髄損傷およびａｌｓの治療のための機能的ニューロンの再生

Country Status (7)

Country Link
US (2) US20210162002A1 (https=)
EP (1) EP4045148A4 (https=)
JP (2) JP2022552003A (https=)
CN (2) CN114364436A (https=)
AU (1) AU2020365130A1 (https=)
CA (1) CA3157523A1 (https=)
WO (1) WO2021076983A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025143118A1 (ja) * 2023-12-27 2025-07-03 アステラス製薬株式会社 脊髄損傷の治療用医薬組成物及び脊髄損傷の非ヒト霊長類動物モデルの作製方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2054079A4 (en) * 2006-07-19 2009-12-23 Univ Florida COMPOSITIONS FOR CELL REPROGRAMMING AND USES THEREOF
US9770471B2 (en) * 2011-08-17 2017-09-26 President And Fellows Of Harvard College Conversion of somatic cells into functional spinal motor neurons, and methods and uses thereof
WO2014015261A1 (en) * 2012-07-19 2014-01-23 The Penn State Research Foundation Regenerating functional neurons for treatment of disease and injury in the nervous system
JP6473077B2 (ja) * 2013-03-21 2019-02-20 国立大学法人京都大学 神経分化誘導用の多能性幹細胞
WO2014201133A1 (en) * 2013-06-11 2014-12-18 President And Fellows Of Harvard College Compositions and methods for improving induced neuron generation
CA2934065C (en) * 2013-10-25 2023-05-09 Qurgen, Inc. Methods, systems and compositions relating to cell conversion via protein-induced in-vivo cell reprogramming
WO2016086092A1 (en) * 2014-11-25 2016-06-02 The Penn State Research Foundation Chemical reprogramming of human glial cells into neurons for brain and spinal cord repair
KR102423442B1 (ko) * 2015-12-11 2022-07-20 캘리포니아 인스티튜트 오브 테크놀로지 아데노-관련 바이러스를 지시하기 위한 타겟팅 펩타이드
US10973930B2 (en) * 2016-02-18 2021-04-13 The Penn State Research Foundation Generating GABAergic neurons in brains
IT201600093825A1 (it) * 2016-09-19 2018-03-19 Fondazione St Italiano Tecnologia Composizione farmaceutica di miRNA e suoi usi terapeutici.
EP3589307B1 (en) * 2017-02-28 2022-02-16 The Penn State Research Foundation Regenerating functional neurons for treatment of neural injury caused by disruption of blood flow
US20200377885A1 (en) * 2017-08-07 2020-12-03 Washington University Compositions and methods for the generation of neurons and uses thereof
WO2022072325A1 (en) * 2020-09-29 2022-04-07 NeuExcell Therapeutics Inc. Neurod1 combination vector

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