JP2022550658A - 膀胱痛症状の緩和を促進するための、膀胱内ヘパリンおよびアルカリ化リドカインによる治療前の、膀胱壁のアルカリ化 - Google Patents

膀胱痛症状の緩和を促進するための、膀胱内ヘパリンおよびアルカリ化リドカインによる治療前の、膀胱壁のアルカリ化 Download PDF

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Publication number
JP2022550658A
JP2022550658A JP2022502409A JP2022502409A JP2022550658A JP 2022550658 A JP2022550658 A JP 2022550658A JP 2022502409 A JP2022502409 A JP 2022502409A JP 2022502409 A JP2022502409 A JP 2022502409A JP 2022550658 A JP2022550658 A JP 2022550658A
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Japan
Prior art keywords
buffer
acid
composition
heparin
tris
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JP2022502409A
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Japanese (ja)
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JP2022550658A5 (enExample
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シー ローウェル パーソンズ
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Publication of JP2022550658A publication Critical patent/JP2022550658A/ja
Publication of JP2022550658A5 publication Critical patent/JP2022550658A5/ja
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M19/00—Local anaesthesia; Hypothermia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Anesthesiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2022502409A 2019-07-18 2020-07-14 膀胱痛症状の緩和を促進するための、膀胱内ヘパリンおよびアルカリ化リドカインによる治療前の、膀胱壁のアルカリ化 Pending JP2022550658A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962875745P 2019-07-18 2019-07-18
US62/875,745 2019-07-18
PCT/US2020/041977 WO2021011566A1 (en) 2019-07-18 2020-07-14 Alkalization of urinary bladder wall prior to treatment with intravesical heparin and alkalinized lidocaine to enhance relief of bladder pain symptoms

Publications (2)

Publication Number Publication Date
JP2022550658A true JP2022550658A (ja) 2022-12-05
JP2022550658A5 JP2022550658A5 (enExample) 2024-06-18

Family

ID=74211195

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022502409A Pending JP2022550658A (ja) 2019-07-18 2020-07-14 膀胱痛症状の緩和を促進するための、膀胱内ヘパリンおよびアルカリ化リドカインによる治療前の、膀胱壁のアルカリ化

Country Status (6)

Country Link
US (1) US20220273587A1 (enExample)
EP (1) EP3998932A4 (enExample)
JP (1) JP2022550658A (enExample)
AU (1) AU2020315353A1 (enExample)
CA (1) CA3147731A1 (enExample)
WO (1) WO2021011566A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12702790B2 (en) 2019-06-13 2026-08-11 Hollister Incorporated Reusable urinary catheter kits
LT3952973T (lt) 2019-06-13 2023-07-10 Hollister Incorporated Daugkartinio naudojimo šlapimo kateterio produktai
WO2020263859A1 (en) 2019-06-25 2020-12-30 Hollister Incorporated Reusable urinary catheter products

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050234013A1 (en) * 2004-01-28 2005-10-20 The Regents Of The University Of California Novel interstitial therapy for immediate symptom relief and chronic therapy in interstitial cystitis
JP2014501782A (ja) * 2011-01-06 2014-01-23 ローウェル パーソンズ、シー．， 局所麻酔剤、ヘパリノイド、及び緩衝剤を含む組成物を製造する方法
JP2016517390A (ja) * 2013-01-28 2016-06-16 ウリゲン ファーマシューティカルズ、インコーポレイテッド ヘパリノイド、即時作用性麻酔薬、及び緩衝液を含む安定組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6183461B1 (en) * 1998-03-11 2001-02-06 Situs Corporation Method for delivering a medication
US20050238733A1 (en) * 2000-01-05 2005-10-27 Richard Henry Topical anesthesia of the urinary bladder
FR2967577B1 (fr) * 2010-11-18 2013-07-12 Advicenne Pharma Composition pharmaceutique comprenant du sel de bicarbonate, et son utilisation comme medicament
JP7862118B2 (ja) 2017-04-12 2026-05-19 ウリゲン ファーマシューティカルズ、インコーポレイテッド 改善された安定性を備えた注射器中に局所麻酔薬、緩衝液、およびグルコサミノグリカンを含む製品

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050234013A1 (en) * 2004-01-28 2005-10-20 The Regents Of The University Of California Novel interstitial therapy for immediate symptom relief and chronic therapy in interstitial cystitis
JP2014501782A (ja) * 2011-01-06 2014-01-23 ローウェル パーソンズ、シー．， 局所麻酔剤、ヘパリノイド、及び緩衝剤を含む組成物を製造する方法
JP2016517390A (ja) * 2013-01-28 2016-06-16 ウリゲン ファーマシューティカルズ、インコーポレイテッド ヘパリノイド、即時作用性麻酔薬、及び緩衝液を含む安定組成物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PARSONS, C. LOWELL ET AL.: "Alkalinized lidocaine and heparin provide immediate relief of pain and urgency in patients with inte", J SEX MED., vol. 9(1):207-12, JPN7024002877, 2012, ISSN: 0005363881 *
UEDA, TOMOHIRO ET AL.: "Urine alkalization improves the problems of pain and sleep in hypersensitive bladder syndrome", INT J UROL., vol. 21(5):512-7, JPN6024026407, 2014, ISSN: 0005363882 *

Also Published As

Publication number Publication date
EP3998932A1 (en) 2022-05-25
US20220273587A1 (en) 2022-09-01
EP3998932A4 (en) 2023-08-16
AU2020315353A1 (en) 2022-03-10
CA3147731A1 (en) 2021-01-21
WO2021011566A1 (en) 2021-01-21

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