JP2022548694A5 - - Google Patents

Info

Publication number
JP2022548694A5
JP2022548694A5 JP2022517380A JP2022517380A JP2022548694A5 JP 2022548694 A5 JP2022548694 A5 JP 2022548694A5 JP 2022517380 A JP2022517380 A JP 2022517380A JP 2022517380 A JP2022517380 A JP 2022517380A JP 2022548694 A5 JP2022548694 A5 JP 2022548694A5
Authority
JP
Japan
Prior art keywords
seq
amino acid
composition according
labeled anti
radioactively labeled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022517380A
Other languages
English (en)
Japanese (ja)
Other versions
JP7826190B2 (ja
JP2022548694A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/051324 external-priority patent/WO2021055638A1/en
Publication of JP2022548694A publication Critical patent/JP2022548694A/ja
Publication of JP2022548694A5 publication Critical patent/JP2022548694A5/ja
Priority to JP2025160144A priority Critical patent/JP2026047359A/ja
Application granted granted Critical
Publication of JP7826190B2 publication Critical patent/JP7826190B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022517380A 2019-09-17 2020-09-17 抗cd45イムノグロブリンの放射能標識およびその使用方法 Active JP7826190B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025160144A JP2026047359A (ja) 2019-09-17 2025-09-26 抗cd45イムノグロブリンの放射能標識およびその使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962901290P 2019-09-17 2019-09-17
US62/901,290 2019-09-17
PCT/US2020/051324 WO2021055638A1 (en) 2019-09-17 2020-09-17 Radiolabeling of anti-cd45 immunoglobulin and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025160144A Division JP2026047359A (ja) 2019-09-17 2025-09-26 抗cd45イムノグロブリンの放射能標識およびその使用方法

Publications (3)

Publication Number Publication Date
JP2022548694A JP2022548694A (ja) 2022-11-21
JP2022548694A5 true JP2022548694A5 (https=) 2023-09-27
JP7826190B2 JP7826190B2 (ja) 2026-03-09

Family

ID=74883490

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022517380A Active JP7826190B2 (ja) 2019-09-17 2020-09-17 抗cd45イムノグロブリンの放射能標識およびその使用方法
JP2025160144A Pending JP2026047359A (ja) 2019-09-17 2025-09-26 抗cd45イムノグロブリンの放射能標識およびその使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025160144A Pending JP2026047359A (ja) 2019-09-17 2025-09-26 抗cd45イムノグロブリンの放射能標識およびその使用方法

Country Status (7)

Country Link
US (1) US12605472B2 (https=)
EP (1) EP4031188A4 (https=)
JP (2) JP7826190B2 (https=)
CN (1) CN114728074A (https=)
AU (1) AU2020350677A1 (https=)
CA (1) CA3154732A1 (https=)
WO (1) WO2021055638A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023137335A2 (en) * 2022-01-11 2023-07-20 Actinium Pharmaceuticals, Inc. Methods for treating cd33-positive hematological malignancies
JP2025510189A (ja) 2022-03-24 2025-04-14 アクティニウム ファーマシューティカルズ インコーポレイテッド ヒト化抗cd45抗体
WO2025064402A1 (en) * 2023-09-22 2025-03-27 St. Jude Children's Research Hospital, Inc. Method for treating sickle cell disease by targeting senescent cells
CN119842630B (zh) * 2024-12-31 2025-12-26 江苏为真生物医药技术股份有限公司 抗人cd45单克隆抗体杂交瘤细胞株及分泌抗体及其制备方法与应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5273738A (en) * 1990-03-03 1993-12-28 Fred Hutchinson Cancer Research Center Radiation delivery to lymphoid and marrow tissues
EP3297684B1 (en) * 2015-05-21 2020-12-23 Actinium Pharmaceuticals, Inc. Infusion administration of conjugated monoclonal antibodies
CN108026526B (zh) * 2015-06-09 2023-05-12 爱迪塔斯医药公司 用于改善移植的crispr/cas相关方法和组合物
AU2016274989A1 (en) 2015-06-12 2017-11-02 Immunomedics, Inc. Disease therapy with chimeric antigen receptor (car) constructs and t cells (car-t) or nk cells (car-nk) expressing car constructs
WO2017155937A1 (en) * 2016-03-07 2017-09-14 Actinium Pharmaceuticals, Inc. Stabilized radiolabeled anti-cd45 immunoglobulin compositions
WO2019084273A1 (en) * 2017-10-25 2019-05-02 Actinium Pharmaceuticals, Inc. METHODS OF ANTI-CD45-BASED LYMPHODEPPLICATION AND USES THEREOF IN COMBINATION WITH ACT-BASED ANTICANCER THERAPIES
US20230132400A9 (en) 2017-11-10 2023-04-27 Actinium Pharmaceuticals, Inc. Combination therapy for treatment of a hematological disease
WO2019136422A1 (en) * 2018-01-08 2019-07-11 Actinum Pharmaceuticals, Inc. Combination immunotherapy and chemotherapy for the treatment of a hematological malignancy
CA3137908A1 (en) 2019-04-25 2020-10-29 Actinium Pharmaceuticals, Inc. Compositions and methods of immunodepletion for the treatment of malignant and non-malignant hematological diseases

Similar Documents

Publication Publication Date Title
JP2022548694A5 (https=)
Knox et al. Yttrium-90-labeled anti-CD20 monoclonal antibody therapy of recurrent B-cell lymphoma.
Pagel et al. Allogeneic hematopoietic cell transplantation after conditioning with 131I–anti-CD45 antibody plus fludarabine and low-dose total body irradiation for elderly patients with advanced acute myeloid leukemia or high-risk myelodysplastic syndrome
MXPA02001398A (es) Tratamiento de pacientes que tienen linfoma no hodgkins con lesion de medula osea con anticuerpos anti-cd20.
US11912780B2 (en) Anti-CD45-based conditioning methods and uses thereof in conjunction with gene-edited cell-based therapies
JP7826190B2 (ja) 抗cd45イムノグロブリンの放射能標識およびその使用方法
JP2023165952A (ja) α線放射免疫療法薬とともにBCL-2インヒビターを使用してがんを処置するための方法
JP2026047359A5 (https=)
Jiang et al. Haploidentical hematopoietic SCT using helical tomotherapy for total-body irradiation and targeted dose boost in patients with high-risk/refractory acute lymphoblastic leukemia
JP2022519196A5 (https=)
TW202440171A (zh) 治療前列腺癌之方法
Wang et al. Venetoclax in combination with hypomethylating agents for the treatment of treatment-naive B/myeloid mixed-phenotype acute leukemia and relapsed/refractory acute myeloid leukemia: a report of 3 cases
Freedman et al. Cyclophosphamide, doxorubicin, vincristine, prednisone dose intensification with granulocyte colony-stimulating factor markedly depletes stem cell reserve for autologous bone marrow transplantation
Yonekura Current treatment strategies and emerging therapies for cutaneous lymphoma
Geldof et al. Combination 186Re-HEDP and cisplatin supra-additive treatment effects in prostate cancer cells
TW202011948A (zh) 接受造血幹細胞移植的患者之血液惡性腫瘤的復發抑制劑
Soignet Management of cancer-related anemia: epoetin alfa and quality of life
Miura et al. An effective salvage treatment using ifosfamide, etoposide, cytarabine, dexamethasone, and rituximab (R-IVAD) for patients with relapsed or refractory aggressive B-cell lymphoma
Kitko et al. Preparing the patient for HSCT: Conditioning regimens and their scientific rationale
Draube et al. German Hodgkin's Lymphoma Study Group trials: lessons from the past and current strategies
EP3958879A1 (en) Compositions and methods of immunodepletion for the treatment of malignant and non-malignant hematological diseases
Sun et al. Autologous peripheral hematopoietic stem-cell transplantation in a patient with refractory pemphigus
Qin Development of targeted alpha particle therapy and identification of sensitizing strategies for efficacious Peptide Receptor Radionuclide Therapy (PRRT) in cancer
HK40028713A (en) Anti-cd45-based conditioning methods and uses thereof in conjunction with gene-edited cell-based therapies
Billett et al. Autologous bone marrow transplantation after a long first remission