JP2022546964A5 - - Google Patents
Info
- Publication number
- JP2022546964A5 JP2022546964A5 JP2022513188A JP2022513188A JP2022546964A5 JP 2022546964 A5 JP2022546964 A5 JP 2022546964A5 JP 2022513188 A JP2022513188 A JP 2022513188A JP 2022513188 A JP2022513188 A JP 2022513188A JP 2022546964 A5 JP2022546964 A5 JP 2022546964A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- peptide ligand
- pbp
- ligand according
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1912320.7A GB201912320D0 (en) | 2019-08-28 | 2019-08-28 | PBP Binding Bicyclic Peptide Ligands |
| GB1912320.7 | 2019-08-28 | ||
| PCT/GB2020/052058 WO2021038232A1 (en) | 2019-08-28 | 2020-08-28 | Pbp binding bicyclic peptide ligands |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022546964A JP2022546964A (ja) | 2022-11-10 |
| JP2022546964A5 true JP2022546964A5 (https=) | 2023-09-05 |
Family
ID=68108985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022513188A Ceased JP2022546964A (ja) | 2019-08-28 | 2020-08-28 | Ｐｂｐ結合二環式ペプチドリガンド |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220281918A1 (https=) |
| EP (1) | EP4021922A1 (https=) |
| JP (1) | JP2022546964A (https=) |
| CN (1) | CN114829374B (https=) |
| GB (1) | GB201912320D0 (https=) |
| WO (1) | WO2021038232A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107148425B (zh) | 2014-10-29 | 2021-08-03 | 拜斯科阿迪有限公司 | 对mt1-mmp特异性的双环肽配体 |
| EP3645549A1 (en) | 2017-06-26 | 2020-05-06 | BicycleRD Limited | Bicyclic peptide ligands with detectable moieties and uses thereof |
| JP7670481B2 (ja) | 2017-08-04 | 2025-04-30 | バイスクルテクス・リミテッド | Ｃｄ１３７に対して特異的な二環式ペプチドリガンド |
| CN111902429A (zh) | 2018-02-23 | 2020-11-06 | 拜斯科技术开发有限公司 | 多聚体双环肽配体 |
| IL279489B2 (en) | 2018-06-22 | 2025-10-01 | Bicycletx Ltd | Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate |
| GB201820295D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for MT1-MMP |
| GB201820325D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for psma |
| GB201820288D0 (en) | 2018-12-13 | 2019-01-30 | Bicycle Tx Ltd | Bicycle peptide ligaands specific for MT1-MMP |
| WO2020128527A1 (en) | 2018-12-21 | 2020-06-25 | Bicyclerd Limited | Bicyclic peptide ligands specific for pd-l1 |
| US12492224B2 (en) | 2018-12-21 | 2025-12-09 | Bicycletx Limited | Bicyclic peptide ligands specific for PD-L1 |
| GB201900529D0 (en) | 2019-01-15 | 2019-03-06 | Bicycletx Ltd | Bicyclic peptide ligands specific for CD38 |
| TWI860386B (zh) | 2019-07-30 | 2024-11-01 | 英商拜西可泰克斯有限公司 | 異質雙環肽複合物 |
| GB202002706D0 (en) * | 2020-02-26 | 2020-04-08 | Bicycletx Ltd | Pbp3 binding bicyclic peptide ligands |
| AU2021322934A1 (en) | 2020-08-03 | 2023-03-30 | Bicycletx Limited | Peptide-based linkers |
| KR20230107589A (ko) * | 2020-11-13 | 2023-07-17 | 바이사이클티엑스 리미티드 | 트랜스페린 수용체 1 (TfR1)에 특이적인 비시클릭 펩티드 리간드 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1452868A2 (en) | 2003-02-27 | 2004-09-01 | Pepscan Systems B.V. | Method for selecting a candidate drug compound |
| WO2006078161A1 (en) | 2005-01-24 | 2006-07-27 | Pepscan Systems B.V. | Binding compounds, immunogenic compounds and peptidomimetics |
| EP2653545A1 (en) | 2008-02-05 | 2013-10-23 | Bicycle Therapeutics Limited | Methods and compositions |
| CN107148425B (zh) * | 2014-10-29 | 2021-08-03 | 拜斯科阿迪有限公司 | 对mt1-mmp特异性的双环肽配体 |
| GB201706477D0 (en) * | 2017-04-24 | 2017-06-07 | Bicycle Therapeutics Ltd | Modification of polypeptides |
| EP3645549A1 (en) * | 2017-06-26 | 2020-05-06 | BicycleRD Limited | Bicyclic peptide ligands with detectable moieties and uses thereof |
| WO2020084305A1 (en) * | 2018-10-23 | 2020-04-30 | Bicycletx Limited | Bicyclic peptide ligands and uses thereof |
-
2019
- 2019-08-28 GB GBGB1912320.7A patent/GB201912320D0/en not_active Ceased
-
2020
- 2020-08-28 WO PCT/GB2020/052058 patent/WO2021038232A1/en not_active Ceased
- 2020-08-28 JP JP2022513188A patent/JP2022546964A/ja not_active Ceased
- 2020-08-28 CN CN202080058189.3A patent/CN114829374B/zh active Active
- 2020-08-28 EP EP20765335.3A patent/EP4021922A1/en not_active Withdrawn
- 2020-08-28 US US17/638,040 patent/US20220281918A1/en active Pending
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