GB201912320D0 - PBP Binding Bicyclic Peptide Ligands - Google Patents

PBP Binding Bicyclic Peptide Ligands

Info

Publication number
GB201912320D0
GB201912320D0 GBGB1912320.7A GB201912320A GB201912320D0 GB 201912320 D0 GB201912320 D0 GB 201912320D0 GB 201912320 A GB201912320 A GB 201912320A GB 201912320 D0 GB201912320 D0 GB 201912320D0
Authority
GB
United Kingdom
Prior art keywords
peptide ligands
bicyclic peptide
binding bicyclic
pbp binding
pbp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1912320.7A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BicycleTx Ltd
Original Assignee
BicycleTx Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BicycleTx Ltd filed Critical BicycleTx Ltd
Priority to GBGB1912320.7A priority Critical patent/GB201912320D0/en
Publication of GB201912320D0 publication Critical patent/GB201912320D0/en
Priority to PCT/GB2020/052058 priority patent/WO2021038232A1/en
Priority to CN202080058189.3A priority patent/CN114829374B/zh
Priority to JP2022513188A priority patent/JP2022546964A/ja
Priority to US17/638,040 priority patent/US20220281918A1/en
Priority to EP20765335.3A priority patent/EP4021922A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
GBGB1912320.7A 2019-08-28 2019-08-28 PBP Binding Bicyclic Peptide Ligands Ceased GB201912320D0 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
GBGB1912320.7A GB201912320D0 (en) 2019-08-28 2019-08-28 PBP Binding Bicyclic Peptide Ligands
PCT/GB2020/052058 WO2021038232A1 (en) 2019-08-28 2020-08-28 Pbp binding bicyclic peptide ligands
CN202080058189.3A CN114829374B (zh) 2019-08-28 2020-08-28 结合pbp的双环肽配体
JP2022513188A JP2022546964A (ja) 2019-08-28 2020-08-28 Ｐｂｐ結合二環式ペプチドリガンド
US17/638,040 US20220281918A1 (en) 2019-08-28 2020-08-28 Pbp binding bicyclic peptide ligands
EP20765335.3A EP4021922A1 (en) 2019-08-28 2020-08-28 Pbp binding bicyclic peptide ligands

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1912320.7A GB201912320D0 (en) 2019-08-28 2019-08-28 PBP Binding Bicyclic Peptide Ligands

Publications (1)

Publication Number Publication Date
GB201912320D0 true GB201912320D0 (en) 2019-10-09

Family

ID=68108985

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1912320.7A Ceased GB201912320D0 (en) 2019-08-28 2019-08-28 PBP Binding Bicyclic Peptide Ligands

Country Status (6)

Country Link
US (1) US20220281918A1 (https=)
EP (1) EP4021922A1 (https=)
JP (1) JP2022546964A (https=)
CN (1) CN114829374B (https=)
GB (1) GB201912320D0 (https=)
WO (1) WO2021038232A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107148425B (zh) 2014-10-29 2021-08-03 拜斯科阿迪有限公司 对mt1-mmp特异性的双环肽配体
EP3645549A1 (en) 2017-06-26 2020-05-06 BicycleRD Limited Bicyclic peptide ligands with detectable moieties and uses thereof
JP7670481B2 (ja) 2017-08-04 2025-04-30 バイスクルテクス・リミテッド Ｃｄ１３７に対して特異的な二環式ペプチドリガンド
CN111902429A (zh) 2018-02-23 2020-11-06 拜斯科技术开发有限公司 多聚体双环肽配体
IL279489B2 (en) 2018-06-22 2025-10-01 Bicycletx Ltd Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate
GB201820295D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for MT1-MMP
GB201820325D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for psma
GB201820288D0 (en) 2018-12-13 2019-01-30 Bicycle Tx Ltd Bicycle peptide ligaands specific for MT1-MMP
WO2020128527A1 (en) 2018-12-21 2020-06-25 Bicyclerd Limited Bicyclic peptide ligands specific for pd-l1
US12492224B2 (en) 2018-12-21 2025-12-09 Bicycletx Limited Bicyclic peptide ligands specific for PD-L1
GB201900529D0 (en) 2019-01-15 2019-03-06 Bicycletx Ltd Bicyclic peptide ligands specific for CD38
TWI860386B (zh) 2019-07-30 2024-11-01 英商拜西可泰克斯有限公司 異質雙環肽複合物
GB202002706D0 (en) * 2020-02-26 2020-04-08 Bicycletx Ltd Pbp3 binding bicyclic peptide ligands
AU2021322934A1 (en) 2020-08-03 2023-03-30 Bicycletx Limited Peptide-based linkers
KR20230107589A (ko) * 2020-11-13 2023-07-17 바이사이클티엑스 리미티드 트랜스페린 수용체 1 (TfR1)에 특이적인 비시클릭 펩티드 리간드

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1452868A2 (en) 2003-02-27 2004-09-01 Pepscan Systems B.V. Method for selecting a candidate drug compound
WO2006078161A1 (en) 2005-01-24 2006-07-27 Pepscan Systems B.V. Binding compounds, immunogenic compounds and peptidomimetics
EP2653545A1 (en) 2008-02-05 2013-10-23 Bicycle Therapeutics Limited Methods and compositions
CN107148425B (zh) * 2014-10-29 2021-08-03 拜斯科阿迪有限公司 对mt1-mmp特异性的双环肽配体
GB201706477D0 (en) * 2017-04-24 2017-06-07 Bicycle Therapeutics Ltd Modification of polypeptides
EP3645549A1 (en) * 2017-06-26 2020-05-06 BicycleRD Limited Bicyclic peptide ligands with detectable moieties and uses thereof
WO2020084305A1 (en) * 2018-10-23 2020-04-30 Bicycletx Limited Bicyclic peptide ligands and uses thereof

Also Published As

Publication number Publication date
CN114829374A (zh) 2022-07-29
JP2022546964A (ja) 2022-11-10
WO2021038232A1 (en) 2021-03-04
CN114829374B (zh) 2025-04-04
EP4021922A1 (en) 2022-07-06
US20220281918A1 (en) 2022-09-08

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)