JP2022545516A5 - - Google Patents
Info
- Publication number
- JP2022545516A5 JP2022545516A5 JP2022512466A JP2022512466A JP2022545516A5 JP 2022545516 A5 JP2022545516 A5 JP 2022545516A5 JP 2022512466 A JP2022512466 A JP 2022512466A JP 2022512466 A JP2022512466 A JP 2022512466A JP 2022545516 A5 JP2022545516 A5 JP 2022545516A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- signaling pathway
- pathway activator
- visceral
- mesoderm cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962892781P | 2019-08-28 | 2019-08-28 | |
| US62/892,781 | 2019-08-28 | ||
| PCT/US2020/047846 WO2021041443A2 (en) | 2019-08-28 | 2020-08-25 | Organoid mesoderm lineage diversification |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022545516A JP2022545516A (ja) | 2022-10-27 |
| JP2022545516A5 true JP2022545516A5 (cg-RX-API-DMAC7.html) | 2024-02-06 |
| JP7780423B2 JP7780423B2 (ja) | 2025-12-04 |
Family
ID=74685212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022512466A Active JP7780423B2 (ja) | 2019-08-28 | 2020-08-25 | オルガノイド中胚葉系統多様化 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220275341A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP4022036A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP7780423B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN114430774A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2020337417A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3150015A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2021041443A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011140441A2 (en) | 2010-05-06 | 2011-11-10 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| ES2860423T3 (es) | 2014-05-28 | 2021-10-05 | Childrens Hospital Med Ct | Métodos y sistemas para convertir células precursoras en tejidos gástricos mediante diferenciación dirigida |
| SG10202104575WA (en) | 2016-11-04 | 2021-06-29 | Childrens Hospital Med Ct | Liver organoid compositions and methods of making and using same |
| US12281334B2 (en) | 2017-04-14 | 2025-04-22 | Children's Hospital Medical Center | Multi donor stem cell compositions and methods of making same |
| WO2019074793A1 (en) | 2017-10-10 | 2019-04-18 | Children's Hospital Medical Center | OESOPHAGIAN TISSUE COMPOSITIONS AND / OR ORGANOIDS AND METHODS OF MAKING SAME |
| US12379372B2 (en) | 2017-12-21 | 2025-08-05 | Children's Hospital Medical Center | Digitalized human organoids and methods of using same |
| CA3106634A1 (en) | 2018-07-26 | 2020-01-30 | Children's Hospital Medical Center | Hepato-biliary-pancreatic tissues and methods of making same |
| CN112823012A (zh) | 2018-09-12 | 2021-05-18 | 儿童医院医学中心 | 用于产生造血干细胞及其衍生物的类器官组合物 |
| WO2020160371A1 (en) | 2019-02-01 | 2020-08-06 | The University Of Hong Kong | Innervated organoid compositions and methods of making same |
| US12534709B2 (en) | 2019-05-31 | 2026-01-27 | Children's Hospital Medical Center | Shaped organoid compositions and methods of making same |
| CA3141807A1 (en) | 2019-05-31 | 2020-12-03 | Children's Hospital Medical Center | Methods of generating and expanding hematopoietic stem cells |
| WO2022066772A1 (en) * | 2020-09-25 | 2022-03-31 | Children´S Hospital Medical Center | Raft cultures and methods of making thereof |
| AU2022304681A1 (en) * | 2021-07-02 | 2024-01-25 | Children’S Hospital Medical Center | Structurally complete organoids |
| WO2023102133A1 (en) * | 2021-12-03 | 2023-06-08 | Children's Hospital Medical Center | Improved methods of preparing different mesoderm cell types |
| WO2024123790A1 (en) * | 2022-12-07 | 2024-06-13 | The Board Of Trustees Of The Leland Stanford Junior University | A method to generate cardiac pericytes from human induced pluripotent stem cells |
| CN116259364A (zh) * | 2022-12-19 | 2023-06-13 | 湖南大学 | 一种基于时间序列单细胞转录组测序数据的细胞轨迹推断方法 |
| WO2025072803A1 (en) | 2023-09-29 | 2025-04-03 | Children's Hospital Medical Center | Ntrk2 signaling-mediated alveolar capillary injury and repair |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7745113B2 (en) * | 2003-01-31 | 2010-06-29 | The Regents Of The University Of California | Use of islet 1 as a marker for isolating or generating stem cells |
| US20110305672A1 (en) * | 2008-07-25 | 2011-12-15 | University Of Georgia Research Foundation, Inc. | COMPOSITIONS FOR MESODERM DERIVED ISL1+ MULTIPOTENT CELLS (IMPs), EPICARDIAL PROGENITOR CELLS (EPCs) AND MULTIPOTENT CD56C CELLS (C56Cs) AND METHODS OF PRODUCING AND USING SAME |
| JP6494515B2 (ja) * | 2012-10-19 | 2019-04-03 | エージェンシー フォー サイエンス， テクノロジー アンド リサーチ | 幹細胞を１又は２以上の細胞系列に分化させる方法 |
| WO2016141084A1 (en) * | 2015-03-03 | 2016-09-09 | The Board Of Trustees Of The Leland Stanford Junior University | Producing mesodermal cell types and methods of using the same |
-
2020
- 2020-08-25 CA CA3150015A patent/CA3150015A1/en active Pending
- 2020-08-25 AU AU2020337417A patent/AU2020337417A1/en not_active Abandoned
- 2020-08-25 EP EP20857981.3A patent/EP4022036A4/en active Pending
- 2020-08-25 US US17/638,753 patent/US20220275341A1/en active Pending
- 2020-08-25 JP JP2022512466A patent/JP7780423B2/ja active Active
- 2020-08-25 WO PCT/US2020/047846 patent/WO2021041443A2/en not_active Ceased
- 2020-08-25 CN CN202080060072.9A patent/CN114430774A/zh active Pending
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