JP2022544485A5 - - Google Patents

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Publication number
JP2022544485A5
JP2022544485A5 JP2022508487A JP2022508487A JP2022544485A5 JP 2022544485 A5 JP2022544485 A5 JP 2022544485A5 JP 2022508487 A JP2022508487 A JP 2022508487A JP 2022508487 A JP2022508487 A JP 2022508487A JP 2022544485 A5 JP2022544485 A5 JP 2022544485A5
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JP
Japan
Application number
JP2022508487A
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Japanese (ja)
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JP2022544485A (ja
JPWO2021030248A5 (https=
JP7667132B2 (ja
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Priority claimed from PCT/US2020/045584 external-priority patent/WO2021030248A1/en
Publication of JP2022544485A publication Critical patent/JP2022544485A/ja
Publication of JPWO2021030248A5 publication Critical patent/JPWO2021030248A5/ja
Publication of JP2022544485A5 publication Critical patent/JP2022544485A5/ja
Priority to JP2025064712A priority Critical patent/JP2025121905A/ja
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Publication of JP7667132B2 publication Critical patent/JP7667132B2/ja
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JP2022508487A 2019-08-12 2020-08-10 Atp競合性akt阻害剤、cdk4/6阻害剤、およびフルベストラントを含む併用療法を使用した乳がんの処置 Active JP7667132B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025064712A JP2025121905A (ja) 2019-08-12 2025-04-10 Atp競合性akt阻害剤、cdk4/6阻害剤、およびフルベストラントを含む併用療法を使用した乳がんの処置

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962885732P 2019-08-12 2019-08-12
US62/885,732 2019-08-12
US201962935526P 2019-11-14 2019-11-14
US62/935,526 2019-11-14
PCT/US2020/045584 WO2021030248A1 (en) 2019-08-12 2020-08-10 Treatment of breast cancer using combination therapies comprising an atp competitive akt inhibitor, a cdk4/6 inhibitor, and fulvestrant

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025064712A Division JP2025121905A (ja) 2019-08-12 2025-04-10 Atp競合性akt阻害剤、cdk4/6阻害剤、およびフルベストラントを含む併用療法を使用した乳がんの処置

Publications (4)

Publication Number Publication Date
JP2022544485A JP2022544485A (ja) 2022-10-19
JPWO2021030248A5 JPWO2021030248A5 (https=) 2023-08-21
JP2022544485A5 true JP2022544485A5 (https=) 2023-08-21
JP7667132B2 JP7667132B2 (ja) 2025-04-22

Family

ID=72193647

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022508487A Active JP7667132B2 (ja) 2019-08-12 2020-08-10 Atp競合性akt阻害剤、cdk4/6阻害剤、およびフルベストラントを含む併用療法を使用した乳がんの処置
JP2025064712A Pending JP2025121905A (ja) 2019-08-12 2025-04-10 Atp競合性akt阻害剤、cdk4/6阻害剤、およびフルベストラントを含む併用療法を使用した乳がんの処置

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025064712A Pending JP2025121905A (ja) 2019-08-12 2025-04-10 Atp競合性akt阻害剤、cdk4/6阻害剤、およびフルベストラントを含む併用療法を使用した乳がんの処置

Country Status (6)

Country Link
US (3) US11576919B2 (https=)
EP (1) EP4013419A1 (https=)
JP (2) JP7667132B2 (https=)
CN (1) CN114206345A (https=)
TW (1) TW202120096A (https=)
WO (1) WO2021030248A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113194941A (zh) 2018-12-19 2021-07-30 基因泰克公司 使用包括akt抑制剂、紫杉烷和pd-l1抑制剂的组合疗法治疗乳腺癌
WO2021030248A1 (en) 2019-08-12 2021-02-18 Genentech, Inc. Treatment of breast cancer using combination therapies comprising an atp competitive akt inhibitor, a cdk4/6 inhibitor, and fulvestrant
CA3240454A1 (en) * 2021-12-10 2023-06-15 Lacey Morgan LITCHFIELD Cdk4 and 6 inhibitor in combination with fulvestrant for the treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced or metastatic breast cancer in patients previously treated with a cdk4 and 6 inhibito
WO2024083716A1 (en) * 2022-10-17 2024-04-25 Astrazeneca Ab Combinations of a serd for the treatment of cancer
IL324442A (en) * 2023-05-05 2026-01-01 Astrazeneca Ab Combination of captopril, a cdk4/6 inhibitor, and fulvestrant for use in the treatment of breast cancer
CN121586576A (zh) * 2023-06-14 2026-02-27 南京正大天晴制药有限公司 Akt抑制剂在制备预防或治疗乳腺癌药物中的用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102021157B1 (ko) * 2011-04-01 2019-09-11 제넨테크, 인크. Akt 억제제 화합물 및 아비라테론의 조합물, 및 사용 방법
HRP20200992T1 (hr) * 2012-05-17 2020-10-16 Genentech, Inc. Amorfni oblik pirimidinil-ciklopentanskog spoja koji inhibira akt, te njegovi pripravci i postupci
JP2017507964A (ja) * 2014-03-13 2017-03-23 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト エストロゲン受容体モジュレーターを用いた治療的組合せ
WO2017161253A1 (en) * 2016-03-18 2017-09-21 Tufts Medical Center Compositions and methods for treating and preventing metabolic disorders
TWI777658B (zh) * 2016-08-10 2022-09-11 瑞士商赫孚孟拉羅股份公司 包含Akt蛋白質激酶抑制劑之醫藥組合物
CN109982701B (zh) 2017-06-21 2022-04-12 江苏恒瑞医药股份有限公司 SERD与CDK4/6抑制剂、PI3K/mTOR通路抑制剂的用途
WO2021030248A1 (en) * 2019-08-12 2021-02-18 Genentech, Inc. Treatment of breast cancer using combination therapies comprising an atp competitive akt inhibitor, a cdk4/6 inhibitor, and fulvestrant
JP2022547735A (ja) * 2019-09-16 2022-11-15 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 乳房がんの分子特徴付けに基づく処置の方法

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