JP2022541591A5 - - Google Patents

Info

Publication number
JP2022541591A5
JP2022541591A5 JP2022503919A JP2022503919A JP2022541591A5 JP 2022541591 A5 JP2022541591 A5 JP 2022541591A5 JP 2022503919 A JP2022503919 A JP 2022503919A JP 2022503919 A JP2022503919 A JP 2022503919A JP 2022541591 A5 JP2022541591 A5 JP 2022541591A5
Authority
JP
Japan
Prior art keywords
approximately
months
pharmaceutical composition
cancer
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022503919A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022541591A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/042865 external-priority patent/WO2021016233A1/en
Publication of JP2022541591A publication Critical patent/JP2022541591A/ja
Publication of JP2022541591A5 publication Critical patent/JP2022541591A5/ja
Pending legal-status Critical Current

Links

JP2022503919A 2019-07-22 2020-07-21 がんの処置のためのヒト化抗liv1抗体 Pending JP2022541591A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962877233P 2019-07-22 2019-07-22
US62/877,233 2019-07-22
US201962890498P 2019-08-22 2019-08-22
US62/890,498 2019-08-22
US202063003613P 2020-04-01 2020-04-01
US63/003,613 2020-04-01
US202063031496P 2020-05-28 2020-05-28
US63/031,496 2020-05-28
PCT/US2020/042865 WO2021016233A1 (en) 2019-07-22 2020-07-21 Humanized anti-liv1 antibodies for the treatment of cancer

Publications (2)

Publication Number Publication Date
JP2022541591A JP2022541591A (ja) 2022-09-26
JP2022541591A5 true JP2022541591A5 (enExample) 2023-07-31

Family

ID=71995150

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022503919A Pending JP2022541591A (ja) 2019-07-22 2020-07-21 がんの処置のためのヒト化抗liv1抗体

Country Status (12)

Country Link
US (2) US20210030885A1 (enExample)
EP (1) EP4004046A1 (enExample)
JP (1) JP2022541591A (enExample)
KR (1) KR20220035486A (enExample)
CN (1) CN114423464A (enExample)
AU (1) AU2020318975A1 (enExample)
BR (1) BR112022001045A2 (enExample)
CA (1) CA3147750A1 (enExample)
IL (1) IL289842A (enExample)
MX (1) MX2022000853A (enExample)
TW (1) TW202116810A (enExample)
WO (1) WO2021016233A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3213636A1 (en) 2021-03-18 2022-09-22 Seagen Inc. Selective drug release from internalized conjugates of biologically active compounds
WO2024165056A1 (en) * 2023-02-07 2024-08-15 LaNova Medicines Limited Antibodies targeting liv-1 and uses thereof
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof
WO2025162207A1 (zh) * 2024-01-31 2025-08-07 上海复宏汉霖生物技术股份有限公司 抗liv1抗体及使用方法
CN120040587B (zh) * 2025-04-27 2025-08-08 上海宏成药业有限公司 抗liv-1抗体或其抗原结合片段及其用途

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US4880935A (en) 1986-07-11 1989-11-14 Icrf (Patents) Limited Heterobifunctional linking agents derived from N-succinimido-dithio-alpha methyl-methylene-benzoates
FI102355B1 (fi) 1988-02-11 1998-11-30 Bristol Myers Squibb Co Menetelmä yhdistävän välikappaleen omaavien antrasykliini-immunokonjugaattien valmistamiseksi
ES2052027T5 (es) 1988-11-11 2005-04-16 Medical Research Council Clonacion de secuencias de dominio variable de inmunoglobulina.
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5859205A (en) 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
ATE255131T1 (de) 1991-06-14 2003-12-15 Genentech Inc Humanisierter heregulin antikörper
US5622929A (en) 1992-01-23 1997-04-22 Bristol-Myers Squibb Company Thioether conjugates
EP0871490B1 (en) 1995-12-22 2003-03-19 Bristol-Myers Squibb Company Branched hydrazone linkers
US6130237A (en) 1996-09-12 2000-10-10 Cancer Research Campaign Technology Limited Condensed N-aclyindoles as antitumor agents
MXPA05000511A (es) 2001-07-12 2005-09-30 Jefferson Foote Anticuepros super humanizados.
ES2544527T3 (es) 2002-07-31 2015-09-01 Seattle Genetics, Inc. Conjugados de fármacos y su uso para tratar el cáncer, una enfermedad autoinmune o una enfermedad infecciosa
WO2004067564A2 (en) 2003-01-29 2004-08-12 Protein Design Labs, Inc. Compositions against cancer antigen liv-1 and uses thereof
EP3434275A1 (en) 2003-11-06 2019-01-30 Seattle Genetics, Inc. Assay for cancer cells based on the use of auristatin conjugates with antibodies
WO2007008848A2 (en) 2005-07-07 2007-01-18 Seattle Genetics, Inc. Monomethylvaline compounds having phenylalanine carboxy modifications at the c-terminus
JP5171621B2 (ja) 2005-07-07 2013-03-27 シアトル ジェネティックス, インコーポレイテッド フェニルアラニン側鎖修飾をc末端に有するモノメチルバリン化合物
WO2009052431A2 (en) 2007-10-19 2009-04-23 Seattle Genetics, Inc. Cd19 binding agents and uses thereof
EP3786185A1 (en) * 2010-12-06 2021-03-03 Seagen Inc. Humanized antibodies to liv-1 and use of same to treat cancer
WO2017202744A1 (en) * 2016-05-26 2017-11-30 Merck Patent Gmbh Pd-1 / pd-l1 inhibitors for cancer treatment
JP6695003B2 (ja) * 2016-09-26 2020-05-20 イムクローン・リミテッド・ライアビリティ・カンパニーImclone LLC 癌のための併用療法
MX2020005640A (es) * 2017-12-01 2020-08-20 Seattle Genetics Inc Anticuerpos anti-liv1 humanizados para el tratamiento de cancer de mama.

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