JP2022541591A5 - - Google Patents

Info

Publication number
JP2022541591A5
JP2022541591A5 JP2022503919A JP2022503919A JP2022541591A5 JP 2022541591 A5 JP2022541591 A5 JP 2022541591A5 JP 2022503919 A JP2022503919 A JP 2022503919A JP 2022503919 A JP2022503919 A JP 2022503919A JP 2022541591 A5 JP2022541591 A5 JP 2022541591A5
Authority
JP
Japan
Prior art keywords
approximately
months
pharmaceutical composition
cancer
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022503919A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022541591A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/042865 external-priority patent/WO2021016233A1/en
Publication of JP2022541591A publication Critical patent/JP2022541591A/ja
Publication of JP2022541591A5 publication Critical patent/JP2022541591A5/ja
Pending legal-status Critical Current

Links

JP2022503919A 2019-07-22 2020-07-21 がんの処置のためのヒト化抗liv1抗体 Pending JP2022541591A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962877233P 2019-07-22 2019-07-22
US62/877,233 2019-07-22
US201962890498P 2019-08-22 2019-08-22
US62/890,498 2019-08-22
US202063003613P 2020-04-01 2020-04-01
US63/003,613 2020-04-01
US202063031496P 2020-05-28 2020-05-28
US63/031,496 2020-05-28
PCT/US2020/042865 WO2021016233A1 (en) 2019-07-22 2020-07-21 Humanized anti-liv1 antibodies for the treatment of cancer

Publications (2)

Publication Number Publication Date
JP2022541591A JP2022541591A (ja) 2022-09-26
JP2022541591A5 true JP2022541591A5 (enExample) 2023-07-31

Family

ID=71995150

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022503919A Pending JP2022541591A (ja) 2019-07-22 2020-07-21 がんの処置のためのヒト化抗liv1抗体

Country Status (12)

Country Link
US (2) US20210030885A1 (enExample)
EP (1) EP4004046A1 (enExample)
JP (1) JP2022541591A (enExample)
KR (1) KR20220035486A (enExample)
CN (1) CN114423464A (enExample)
AU (1) AU2020318975A1 (enExample)
BR (1) BR112022001045A2 (enExample)
CA (1) CA3147750A1 (enExample)
IL (1) IL289842A (enExample)
MX (1) MX2022000853A (enExample)
TW (1) TW202116810A (enExample)
WO (1) WO2021016233A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024510435A (ja) 2021-03-18 2024-03-07 シージェン インコーポレイテッド 生体活性化合物の内部移行複合体からの選択的薬物放出
IL322565A (en) 2023-02-07 2025-10-01 Lanova Medicines Ltd Antibodies targeting liv-1 and their uses
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof
WO2025162207A1 (zh) * 2024-01-31 2025-08-07 上海复宏汉霖生物技术股份有限公司 抗liv1抗体及使用方法
CN120040587B (zh) * 2025-04-27 2025-08-08 上海宏成药业有限公司 抗liv-1抗体或其抗原结合片段及其用途

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US4880935A (en) 1986-07-11 1989-11-14 Icrf (Patents) Limited Heterobifunctional linking agents derived from N-succinimido-dithio-alpha methyl-methylene-benzoates
IL89220A (en) 1988-02-11 1994-02-27 Bristol Myers Squibb Co Anthracycline immunoconjugates, their production and pharmaceutical compositions containing them
FI903489A7 (fi) 1988-11-11 1990-07-10 Medical Res Council Yhden osan sisältävät ligandit, näitä ligandeja sisältävät reseptorit, menetelmiä niiden valmistamiseksi sekä ligandien ja reseptorien käytt ö
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5859205A (en) 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
EP0590058B1 (en) 1991-06-14 2003-11-26 Genentech, Inc. HUMANIZED Heregulin ANTIBODy
US5622929A (en) 1992-01-23 1997-04-22 Bristol-Myers Squibb Company Thioether conjugates
EP0871490B1 (en) 1995-12-22 2003-03-19 Bristol-Myers Squibb Company Branched hydrazone linkers
US6130237A (en) 1996-09-12 2000-10-10 Cancer Research Campaign Technology Limited Condensed N-aclyindoles as antitumor agents
AU2002368077B2 (en) 2001-07-12 2010-03-04 Jefferson Foote Super humanized antibodies
ES2369542T3 (es) 2002-07-31 2011-12-01 Seattle Genetics, Inc. Conjugados de auristatina y su uso para tratar cáncer, una enfermedad autoinmune o una enfermedad infecciosa.
WO2004067564A2 (en) 2003-01-29 2004-08-12 Protein Design Labs, Inc. Compositions against cancer antigen liv-1 and uses thereof
ES2605443T3 (es) 2003-11-06 2017-03-14 Seattle Genetics, Inc. Conjugados de auristatina con anticuerpos anti-HER2 o anti-CD22 y su uso en terapia
ES2708763T3 (es) 2005-07-07 2019-04-11 Seattle Genetics Inc Compuestos de monometilvalina que tienen modificaciones de la cadena lateral de fenilalanina en el extremo C
WO2007008848A2 (en) 2005-07-07 2007-01-18 Seattle Genetics, Inc. Monomethylvaline compounds having phenylalanine carboxy modifications at the c-terminus
CN101903403B (zh) 2007-10-19 2016-03-16 西雅图基因公司 Cd19结合剂及其应用
PT3156420T (pt) * 2010-12-06 2019-05-27 Seattle Genetics Inc Anticorpos humanizados a liv-1 e seu uso para tratar o cancro
CA3025391A1 (en) * 2016-05-26 2017-11-30 Merck Patent Gmbh Pd-1 / pd-l1 inhibitors for cancer treatment
US20190233523A1 (en) * 2016-09-26 2019-08-01 Imclone Llc Combination therapy for cancer
CA3084495A1 (en) * 2017-12-01 2019-06-06 Seattle Genetics, Inc. Humanized anti-liv1 antibodies for the treatment of breast cancer

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