JP2022541435A5 - - Google Patents
Info
- Publication number
- JP2022541435A5 JP2022541435A5 JP2022502205A JP2022502205A JP2022541435A5 JP 2022541435 A5 JP2022541435 A5 JP 2022541435A5 JP 2022502205 A JP2022502205 A JP 2022502205A JP 2022502205 A JP2022502205 A JP 2022502205A JP 2022541435 A5 JP2022541435 A5 JP 2022541435A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- acid sequence
- cdr1
- variable region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024193280A JP2025032078A (ja) | 2019-07-17 | 2024-11-01 | クローディン１８抗体及びがんを処置する方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962875416P | 2019-07-17 | 2019-07-17 | |
| US62/875,416 | 2019-07-17 | ||
| PCT/US2020/042573 WO2021011885A1 (en) | 2019-07-17 | 2020-07-17 | Claudin18 antibodies and methods of treating cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024193280A Division JP2025032078A (ja) | 2019-07-17 | 2024-11-01 | クローディン１８抗体及びがんを処置する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022541435A JP2022541435A (ja) | 2022-09-26 |
| JP2022541435A5 true JP2022541435A5 (enExample) | 2023-07-26 |
Family
ID=74211179
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022502205A Pending JP2022541435A (ja) | 2019-07-17 | 2020-07-17 | クローディン１８抗体及びがんを処置する方法 |
| JP2024193280A Pending JP2025032078A (ja) | 2019-07-17 | 2024-11-01 | クローディン１８抗体及びがんを処置する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024193280A Pending JP2025032078A (ja) | 2019-07-17 | 2024-11-01 | クローディン１８抗体及びがんを処置する方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US12345709B2 (enExample) |
| EP (1) | EP3999548A4 (enExample) |
| JP (2) | JP2022541435A (enExample) |
| KR (2) | KR102777693B1 (enExample) |
| CN (1) | CN114364701A (enExample) |
| AU (2) | AU2020313978B2 (enExample) |
| BR (1) | BR112022000371A2 (enExample) |
| CA (1) | CA3146665A1 (enExample) |
| IL (2) | IL289663B2 (enExample) |
| MX (1) | MX2022000652A (enExample) |
| WO (1) | WO2021011885A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11202108398YA (en) | 2019-02-01 | 2021-08-30 | Novarock Biotherapeutics Ltd | Anti-claudin 18 antibodies and methods of use thereof |
| KR102777693B1 (ko) | 2019-07-17 | 2025-03-07 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | Claudin18 항체 및 암 치료 방법 |
| AU2021354827A1 (en) * | 2020-09-30 | 2023-06-01 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Pharmaceutical composition comprising antibody-drug conjugate, and use of pharmaceutical composition |
| US11739144B2 (en) | 2021-03-09 | 2023-08-29 | Xencor, Inc. | Heterodimeric antibodies that bind CD3 and CLDN6 |
| AU2022275043B2 (en) | 2021-05-08 | 2025-11-20 | Remegen Co., Ltd. | Anti-Claudin 18.2 antibody and antibody-drug conjugate thereof |
| WO2022266219A1 (en) * | 2021-06-15 | 2022-12-22 | Xencor, Inc. | Heterodimeric antibodies that bind claudin18.2 and cd3 |
| WO2022268200A1 (zh) * | 2021-06-25 | 2022-12-29 | 信达生物制药(苏州)有限公司 | 针对密蛋白18.2的抗体及其用途 |
| IL310578A (en) * | 2021-08-09 | 2024-03-01 | Harbour Biomed Shanghai Co Ltd | Cldn18.2-targeting antibody, bispecific antibody and use thereof |
| JP2024540062A (ja) * | 2021-11-05 | 2024-10-31 | チア タイ ティエンチン ファーマシューティカル グループ カンパニー リミテッド | 抗ｃｌｄｎ１８．２抗体及びその用途 |
| WO2023196742A1 (en) * | 2022-04-08 | 2023-10-12 | Fred Hutchinson Cancer Center | Anti-cd90 antibodies, binding fragments, and uses thereof |
| CN119894929A (zh) * | 2022-06-03 | 2025-04-25 | 礼新医药科技(上海)有限公司 | 使用PD-1或PD-L1抑制剂和靶向Claudin 18.2的抗体药物偶联物的癌症治疗 |
| WO2024114667A1 (zh) * | 2022-11-30 | 2024-06-06 | 正大天晴药业集团股份有限公司 | 抗cldn18.2抗体药物偶联物及其药物组合物和用途 |
| JP2026501506A (ja) * | 2022-12-14 | 2026-01-16 | アステラス・ファーマ・ヨーロッパ・ベスローデン・フェンノートシャップ | Ｃｌｄｎ１８．２及びｃｄ３に結合する二重特異性結合剤並びに免疫チェックポイント阻害剤を含む併用療法 |
| WO2024226646A2 (en) * | 2023-04-25 | 2024-10-31 | Memorial Sloan-Kettering Cancer Center | Dlk1 -targeting antibodies and uses thereof |
| US20250049810A1 (en) | 2023-08-07 | 2025-02-13 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| AU2024360465A1 (en) | 2023-10-12 | 2026-04-09 | Revolution Medicines, Inc. | Macrocyclic ras inhibitors |
| WO2025078686A1 (en) | 2023-10-12 | 2025-04-17 | Sotio Biotech A.S. | Combination therapy involving antibody-drug conjugates against claudin18.2 and pd1/pd-l axis inhibitors for treatment of cancer |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025206223A1 (ja) * | 2024-03-28 | 2025-10-02 | 早智子 月田 | 抗ヒトクローディン１８．２抗体及びその使用 |
| KR20250154059A (ko) | 2024-04-19 | 2025-10-28 | 강원대학교산학협력단 | Cldn18 단백질 또는 이를 코딩하는 유전자, 또는 프로모터 부위가 메틸화된 cldn18을 유효성분으로 포함하는 폐포 내 미세먼지 노출 진단용 바이오마커 조성물 |
| TW202547461A (zh) | 2024-05-17 | 2025-12-16 | 美商銳新醫藥公司 | Ｒａｓ抑制劑 |
| WO2025255438A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025265060A1 (en) | 2024-06-21 | 2025-12-26 | Revolution Medicines, Inc. | Therapeutic compositions and methods for managing treatment-related effects |
| WO2026006747A1 (en) | 2024-06-28 | 2026-01-02 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026015796A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015790A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015801A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015825A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Use of ras inhibitor for treating pancreatic cancer |
| WO2026050446A1 (en) | 2024-08-29 | 2026-03-05 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026072904A2 (en) | 2024-09-26 | 2026-04-02 | Revolution Medicines, Inc. | Compositions and methods for treating lung cancer |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1997832A1 (en) * | 2007-05-29 | 2008-12-03 | Ganymed Pharmaceuticals AG | Monoclonal antibodies against Claudin-18 for treatment of cancer |
| WO2014146672A1 (en) | 2013-03-18 | 2014-09-25 | Ganymed Pharmaceuticals Ag | Therapy involving antibodies against claudin 18.2 for treatment of cancer |
| WO2016165762A1 (en) * | 2015-04-15 | 2016-10-20 | Ganymed Pharmaceuticals Ag | Drug conjugates comprising antibodies against claudin 18.2 |
| ES2979068T3 (es) * | 2016-07-08 | 2024-09-24 | Crage Medical Co Ltd | Anticuerpos para anti-claudina 18A2 y utilización de los mismos |
| WO2018054484A1 (en) | 2016-09-23 | 2018-03-29 | Biontech Ag | Bispecific trivalent antibodies binding to claudin 6 or claudin18.2 and cd3 for treatment of claudin expressing cancer diseases |
| SG11202007055QA (en) * | 2018-03-08 | 2020-09-29 | Phanes Therapeutics Inc | Anti-claudin 18.2 antibodies and uses thereof |
| WO2020025792A1 (en) * | 2018-08-03 | 2020-02-06 | Amgen Research (Munich) Gmbh | Antibody constructs for cldn18.2 and cd3 |
| CN109762067B (zh) * | 2019-01-17 | 2020-02-28 | 北京天广实生物技术股份有限公司 | 结合人Claudin 18.2的抗体及其用途 |
| KR102777693B1 (ko) | 2019-07-17 | 2025-03-07 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | Claudin18 항체 및 암 치료 방법 |
-
2020
- 2020-07-17 KR KR1020227004165A patent/KR102777693B1/ko active Active
- 2020-07-17 BR BR112022000371A patent/BR112022000371A2/pt unknown
- 2020-07-17 IL IL289663A patent/IL289663B2/en unknown
- 2020-07-17 EP EP20839947.7A patent/EP3999548A4/en active Pending
- 2020-07-17 IL IL313807A patent/IL313807A/en unknown
- 2020-07-17 JP JP2022502205A patent/JP2022541435A/ja active Pending
- 2020-07-17 AU AU2020313978A patent/AU2020313978B2/en active Active
- 2020-07-17 MX MX2022000652A patent/MX2022000652A/es unknown
- 2020-07-17 CN CN202080062500.1A patent/CN114364701A/zh active Pending
- 2020-07-17 WO PCT/US2020/042573 patent/WO2021011885A1/en not_active Ceased
- 2020-07-17 KR KR1020257007047A patent/KR20250044762A/ko active Pending
- 2020-07-17 CA CA3146665A patent/CA3146665A1/en active Pending
- 2020-07-17 US US17/627,540 patent/US12345709B2/en active Active
-
2022
- 2022-10-03 US US17/959,104 patent/US11834499B1/en active Active
-
2024
- 2024-11-01 JP JP2024193280A patent/JP2025032078A/ja active Pending
-
2025
- 2025-05-27 US US19/219,107 patent/US20260104418A1/en active Pending
- 2025-08-04 AU AU2025210899A patent/AU2025210899A1/en active Pending
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