JP2022537493A5 - - Google Patents

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Publication number
JP2022537493A5
JP2022537493A5 JP2021569300A JP2021569300A JP2022537493A5 JP 2022537493 A5 JP2022537493 A5 JP 2022537493A5 JP 2021569300 A JP2021569300 A JP 2021569300A JP 2021569300 A JP2021569300 A JP 2021569300A JP 2022537493 A5 JP2022537493 A5 JP 2022537493A5
Authority
JP
Japan
Prior art keywords
phenoxy
dihydroisoxazole
bromo
butoxy
propanoate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021569300A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022537493A (ja
JP7595945B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2020/067065 external-priority patent/WO2020254554A1/en
Publication of JP2022537493A publication Critical patent/JP2022537493A/ja
Publication of JP2022537493A5 publication Critical patent/JP2022537493A5/ja
Application granted granted Critical
Publication of JP7595945B2 publication Critical patent/JP7595945B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021569300A 2019-06-19 2020-06-19 Ｃｉｃ－１塩化物チャネル阻害剤の調製のためのプロセス Active JP7595945B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19181262 2019-06-19
EP19181262.7 2019-06-19
PCT/EP2020/067065 WO2020254554A1 (en) 2019-06-19 2020-06-19 Process for the preparation of clc-1 chloride channel inhibitors

Publications (3)

Publication Number Publication Date
JP2022537493A JP2022537493A (ja) 2022-08-26
JP2022537493A5 true JP2022537493A5 (https=) 2023-06-27
JP7595945B2 JP7595945B2 (ja) 2024-12-09

Family

ID=66999603

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021569300A Active JP7595945B2 (ja) 2019-06-19 2020-06-19 Ｃｉｃ－１塩化物チャネル阻害剤の調製のためのプロセス

Country Status (18)

Country Link
US (1) US12221425B2 (https=)
EP (1) EP3986878B1 (https=)
JP (1) JP7595945B2 (https=)
KR (1) KR102900834B1 (https=)
CN (1) CN113993852B (https=)
AR (1) AR119198A1 (https=)
AU (1) AU2020298092B2 (https=)
BR (1) BR112021025588A2 (https=)
CA (1) CA3137672A1 (https=)
ES (1) ES3000437T3 (https=)
HU (1) HUE069104T2 (https=)
IL (1) IL287901B2 (https=)
MX (1) MX2021013507A (https=)
PL (1) PL3986878T3 (https=)
SG (1) SG11202111122RA (https=)
TW (1) TWI849152B (https=)
WO (1) WO2020254554A1 (https=)
ZA (1) ZA202107653B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4593829A1 (en) 2022-09-30 2025-08-06 NMD Pharma A/S Compositions and methods for treating myasthenia gravis
WO2024180199A1 (en) 2023-03-02 2024-09-06 Nmd Pharma A/S Compositions and methods for treating charcot–marie–tooth disease
JP2026508357A (ja) 2023-03-02 2026-03-10 エヌエムディー ファーマ エー／エス 脊髄性筋萎縮症を処置するための組成物及び方法
EP4731200A1 (en) 2023-06-20 2026-04-29 NMD Pharma A/S Clc-1 inhibitors for use in the treatment of multiple sclerosis and neuromuscular diseases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0301010D0 (sv) * 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
GB0422057D0 (en) * 2004-10-05 2004-11-03 Astrazeneca Ab Novel compounds
GB0524428D0 (en) * 2005-11-30 2006-01-11 7Tm Pharma As Medicinal use of receptor ligands
WO2009097970A1 (de) * 2008-02-05 2009-08-13 Sanofi-Aventis Triazolopyridazine als par1-inhibitoren, ihre herstellung und verwendung als arzneimittel
JP2015505560A (ja) * 2012-02-03 2015-02-23 ゾエティス・エルエルシー 抗寄生虫薬としてのキラルイソオキサゾリンアゼチジン誘導体の製造法
MX389242B (es) 2015-06-15 2025-03-20 Nmd Pharma As Compuestos para su uso en el tratamiento de trastornos neuromusculares
US10385028B2 (en) * 2017-12-14 2019-08-20 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
TWI780281B (zh) 2017-12-14 2022-10-11 丹麥商Ｎｍｄ藥品公司 用於治療神經肌肉病症的化合物

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