JP2022534979A5 - - Google Patents

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Publication number
JP2022534979A5
JP2022534979A5 JP2021570866A JP2021570866A JP2022534979A5 JP 2022534979 A5 JP2022534979 A5 JP 2022534979A5 JP 2021570866 A JP2021570866 A JP 2021570866A JP 2021570866 A JP2021570866 A JP 2021570866A JP 2022534979 A5 JP2022534979 A5 JP 2022534979A5
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JP
Japan
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JP2021570866A
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Japanese (ja)
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JP2022534979A (ja
JPWO2020243379A5 (https=
JP7496838B2 (ja
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Priority claimed from PCT/US2020/035043 external-priority patent/WO2020243379A1/en
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Priority to JP2024086242A priority Critical patent/JP2024123001A/ja
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JP2021570866A 2019-05-31 2020-05-29 置換1-オキソ-イソインドリン-5-カルボキサミド化合物、その組成物、およびそれによる治療方法 Active JP7496838B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024086242A JP2024123001A (ja) 2019-05-31 2024-05-28 置換1-オキソ-イソインドリン-5-カルボキサミド化合物、その組成物、およびそれによる治療方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962855619P 2019-05-31 2019-05-31
US62/855,619 2019-05-31
PCT/US2020/035043 WO2020243379A1 (en) 2019-05-31 2020-05-29 Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024086242A Division JP2024123001A (ja) 2019-05-31 2024-05-28 置換1-オキソ-イソインドリン-5-カルボキサミド化合物、その組成物、およびそれによる治療方法

Publications (4)

Publication Number Publication Date
JP2022534979A JP2022534979A (ja) 2022-08-04
JPWO2020243379A5 JPWO2020243379A5 (https=) 2023-05-30
JP2022534979A5 true JP2022534979A5 (https=) 2023-05-30
JP7496838B2 JP7496838B2 (ja) 2024-06-07

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ID=73551319

Family Applications (2)

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JP2021570866A Active JP7496838B2 (ja) 2019-05-31 2020-05-29 置換1-オキソ-イソインドリン-5-カルボキサミド化合物、その組成物、およびそれによる治療方法
JP2024086242A Pending JP2024123001A (ja) 2019-05-31 2024-05-28 置換1-オキソ-イソインドリン-5-カルボキサミド化合物、その組成物、およびそれによる治療方法

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JP2024086242A Pending JP2024123001A (ja) 2019-05-31 2024-05-28 置換1-オキソ-イソインドリン-5-カルボキサミド化合物、その組成物、およびそれによる治療方法

Country Status (19)

Country Link
US (2) US11306101B2 (https=)
EP (1) EP3976595A4 (https=)
JP (2) JP7496838B2 (https=)
KR (2) KR20250078628A (https=)
CN (4) CN119930578A (https=)
AR (1) AR119057A1 (https=)
AU (1) AU2020282748A1 (https=)
BR (1) BR112021022758A2 (https=)
CA (1) CA3136753A1 (https=)
CL (1) CL2021003134A1 (https=)
CO (1) CO2021015624A2 (https=)
IL (1) IL288278B2 (https=)
MX (1) MX2021014350A (https=)
MY (1) MY208545A (https=)
PE (1) PE20220569A1 (https=)
SG (1) SG11202112872YA (https=)
TW (2) TW202523657A (https=)
WO (1) WO2020243379A1 (https=)
ZA (1) ZA202109003B (https=)

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WO2020243379A1 (en) 2019-05-31 2020-12-03 Celgene Corporation Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith
IL302038A (en) * 2020-10-14 2023-06-01 C4 Therapeutics Inc Tricyclic ligands for degradation of ikzf2 or ikzf4
CN112679421A (zh) * 2021-01-04 2021-04-20 都创(上海)医药科技股份有限公司 一种(r)-3-氯吡啶基-2-三氟乙胺盐酸盐的合成方法
JP2024504932A (ja) 2021-01-13 2024-02-02 モンテ ローザ セラピューティクス, インコーポレイテッド イソインドリノン化合物
CN118019534A (zh) * 2021-05-06 2024-05-10 细胞基因公司 使用n-((r)-1-(3-氯吡啶-2-基)-2,2,2-三氟乙基)-2-((s)-2,6-二氧代哌啶-3-基)-1-氧代异吲哚啉-5-甲酰胺的治疗方法
US20240294500A1 (en) * 2021-06-08 2024-09-05 Hangzhou Glubio Pharmaceutical Co., Ltd. Isoindolinone compounds, and uses thereof
CN115504963A (zh) * 2021-06-22 2022-12-23 苏州开拓药业股份有限公司 一种c-Myc蛋白降解剂
EP4452415B1 (en) 2021-12-22 2026-02-25 Gilead Sciences, Inc. Ikaros zinc finger family degraders and uses thereof
CA3253296A1 (en) 2022-03-17 2023-09-21 Gilead Sciences, Inc. Zinc Finger Degradation Agents of the Ikaros Family and Their Uses
WO2023244815A1 (en) * 2022-06-16 2023-12-21 Monte Rosa Therapeutics, Inc. Molecular glue degraders and methods of using the same
WO2023244818A1 (en) * 2022-06-16 2023-12-21 Monte Rosa Therapeutics, Inc. Molecular glue degraders and methods of using the same
US20260055077A1 (en) * 2022-08-01 2026-02-26 Suzhou Kintor Pharmaceuticals, Inc. Protein degradation agent
WO2024120441A1 (zh) * 2022-12-07 2024-06-13 杭州格博生物医药有限公司 氧异吲哚-5-甲酰胺类化合物或其盐、溶剂合物的结晶形式或无定形形式
WO2024120438A1 (zh) * 2022-12-07 2024-06-13 杭州格博生物医药有限公司 一种固体分散体、其制备方法和应用
PL249026B1 (pl) * 2022-12-09 2026-02-23 Univ Mikolaja Kopernika W Toruniu Pochodna azetydyno-2,4-dionu, sposób jej otrzymywania i zastosowanie

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Publication number Priority date Publication date Assignee Title
US20030045552A1 (en) * 2000-12-27 2003-03-06 Robarge Michael J. Isoindole-imide compounds, compositions, and uses thereof
US7091353B2 (en) * 2000-12-27 2006-08-15 Celgene Corporation Isoindole-imide compounds, compositions, and uses thereof
KR20080042158A (ko) * 2005-08-31 2008-05-14 셀진 코포레이션 이소인돌-이미드 화합물과 이를 포함하는 조성물 및 이를이용한 방법
MX2009001989A (es) 2006-08-30 2009-03-09 Celgene Corp Compuestos de isoindolina 5-substituidos.
US8877780B2 (en) * 2006-08-30 2014-11-04 Celgene Corporation 5-substituted isoindoline compounds
ZA200901078B (en) * 2006-08-30 2010-06-30 Celgene Corp 5-substituted isoindoline compounds
US9499514B2 (en) * 2014-07-11 2016-11-22 Celgene Corporation Antiproliferative compounds and methods of use thereof
WO2017007612A1 (en) 2015-07-07 2017-01-12 Dana-Farber Cancer Institute, Inc. Methods to induce targeted protein degradation through bifunctional molecules
WO2017024318A1 (en) * 2015-08-06 2017-02-09 Dana-Farber Cancer Institute, Inc. Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses
WO2017024317A2 (en) * 2015-08-06 2017-02-09 Dana-Farber Cancer Institute, Inc. Methods to induce targeted protein degradation through bifunctional molecules
WO2020243379A1 (en) 2019-05-31 2020-12-03 Celgene Corporation Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith

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