JP2022534966A5 - - Google Patents

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Publication number
JP2022534966A5
JP2022534966A5 JP2021570756A JP2021570756A JP2022534966A5 JP 2022534966 A5 JP2022534966 A5 JP 2022534966A5 JP 2021570756 A JP2021570756 A JP 2021570756A JP 2021570756 A JP2021570756 A JP 2021570756A JP 2022534966 A5 JP2022534966 A5 JP 2022534966A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
sequence
actrii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021570756A
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English (en)
Japanese (ja)
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JP7669291B2 (ja
JP2022534966A (ja
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Priority claimed from PCT/US2020/035148 external-priority patent/WO2020243448A1/en
Publication of JP2022534966A publication Critical patent/JP2022534966A/ja
Publication of JP2022534966A5 publication Critical patent/JP2022534966A5/ja
Priority to JP2025067310A priority Critical patent/JP2025118664A/ja
Application granted granted Critical
Publication of JP7669291B2 publication Critical patent/JP7669291B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021570756A 2019-05-30 2020-05-29 Actrii結合性タンパク質及びその使用 Active JP7669291B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025067310A JP2025118664A (ja) 2019-05-30 2025-04-16 Actrii結合性タンパク質及びその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962854625P 2019-05-30 2019-05-30
US62/854,625 2019-05-30
PCT/US2020/035148 WO2020243448A1 (en) 2019-05-30 2020-05-29 Actrii-binding proteins and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025067310A Division JP2025118664A (ja) 2019-05-30 2025-04-16 Actrii結合性タンパク質及びその使用

Publications (3)

Publication Number Publication Date
JP2022534966A JP2022534966A (ja) 2022-08-04
JP2022534966A5 true JP2022534966A5 (https=) 2023-06-06
JP7669291B2 JP7669291B2 (ja) 2025-04-28

Family

ID=73553540

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021570756A Active JP7669291B2 (ja) 2019-05-30 2020-05-29 Actrii結合性タンパク質及びその使用
JP2025067310A Pending JP2025118664A (ja) 2019-05-30 2025-04-16 Actrii結合性タンパク質及びその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025067310A Pending JP2025118664A (ja) 2019-05-30 2025-04-16 Actrii結合性タンパク質及びその使用

Country Status (8)

Country Link
US (1) US12545736B2 (https=)
EP (1) EP3976630A4 (https=)
JP (2) JP7669291B2 (https=)
KR (1) KR20220029563A (https=)
CN (1) CN114127087A (https=)
AU (1) AU2020284038A1 (https=)
CA (1) CA3142149A1 (https=)
WO (1) WO2020243448A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7669291B2 (ja) 2019-05-30 2025-04-28 アクセレロン ファーマ インコーポレーテッド Actrii結合性タンパク質及びその使用
WO2022192411A1 (en) * 2021-03-10 2022-09-15 Acceleron Pharma Inc. Actrii-alk4 antagonists and methods of treating heart failure
JP2024511315A (ja) * 2021-03-10 2024-03-13 アクセルロン ファーマ インコーポレイテッド Actrii-alk4アンタゴニスト及び心不全の治療方法
TW202328190A (zh) * 2021-09-03 2023-07-16 大陸商來凱醫藥科技(上海)有限公司 抗acvr2a抗體及其用途
WO2025027052A1 (en) 2023-07-31 2025-02-06 Sixpeaks Bio Ag Antibody conjugates and fusion proteins
WO2025026353A1 (en) * 2023-08-01 2025-02-06 Laekna Therapeutics Shanghai Co., Ltd. Anti-acvr2b antibodies and uses thereof
TW202521582A (zh) * 2023-09-28 2025-06-01 瑞士商六峰生物股份有限公司 靶向ActRIIA及ActRIIB之抗體
CN121344183B (zh) * 2025-12-18 2026-03-27 成都医学院 检测ACVR2b的试剂在制备慢性肾脏病血管钙化诊断试剂盒中的用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2007002567A1 (es) * 2006-09-08 2008-02-01 Amgen Inc Proteinas aisladas de enlace a activina a humana.
PE20120532A1 (es) 2009-04-27 2012-05-18 Novartis Ag ANTICUERPOS ANTI-ActRIIB
US8765385B2 (en) 2011-10-27 2014-07-01 Ravindra Kumar Method of detection of neutralizing anti-actriib antibodies
GR1007832B (el) * 2011-11-21 2013-02-14 Ιδρυμα Ιατροβιολογικων Ερευνων Ακαδημιας Αθηνων, Αδρανοποιητες της ακτιβινης και χρηση τους για την θεραπεια ασθενειων που σχετιζονται με παρεκκλινουσα ενεργοποιηση της "αμυντικης αποκρισης του ξενιστη"
NZ703724A (en) 2012-06-11 2017-06-30 Amgen Inc Dual receptor antagonistic antigen-binding proteins and uses thereof
WO2014172448A2 (en) 2013-04-17 2014-10-23 Anaptysbio, Inc. Antibodies directed against activin receptor type ii (actrii)
TW201920262A (zh) 2013-07-30 2019-06-01 美商再生元醫藥公司 抗活化素a之抗體及其用途
CA2983440C (en) 2015-04-22 2024-03-12 Alivegen Usa Inc. Novel hybrid actriib ligand trap proteins for treating muscle wasting diseases
US20170240639A1 (en) * 2016-02-22 2017-08-24 Acceleron Pharma Inc. Actrii antagonists for use in increasing immune activity
CN116284392A (zh) * 2016-03-10 2023-06-23 艾科赛扬制药股份有限公司 活化素2型受体结合蛋白及其用途
LT3600415T (lt) 2017-03-24 2025-12-29 Novartis Ag Antikūnas prieš ii tipo aktivino receptorių, skirtas naudoti širdies nepakankamumo gydymui
JP7669291B2 (ja) 2019-05-30 2025-04-28 アクセレロン ファーマ インコーポレーテッド Actrii結合性タンパク質及びその使用

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