JP2022533939A - 線維芽細胞増殖因子受容体キナーゼの阻害剤 - Google Patents

線維芽細胞増殖因子受容体キナーゼの阻害剤 Download PDF

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JP2022533939A
JP2022533939A JP2021567059A JP2021567059A JP2022533939A JP 2022533939 A JP2022533939 A JP 2022533939A JP 2021567059 A JP2021567059 A JP 2021567059A JP 2021567059 A JP2021567059 A JP 2021567059A JP 2022533939 A JP2022533939 A JP 2022533939A
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JP2022533939A5 (enExample
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カルドー，ステファン，ダブリュー．
ティホナス，ジョン
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キネート バイオファーマ インク．
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2021567059A 2019-05-17 2020-05-14 線維芽細胞増殖因子受容体キナーゼの阻害剤 Pending JP2022533939A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962849534P 2019-05-17 2019-05-17
US62/849,534 2019-05-17
US201962907491P 2019-09-27 2019-09-27
US62/907,491 2019-09-27
PCT/US2020/032939 WO2020236524A1 (en) 2019-05-17 2020-05-14 Inhibitors of fibroblast growth factor receptor kinases

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JP2022533939A true JP2022533939A (ja) 2022-07-27
JP2022533939A5 JP2022533939A5 (enExample) 2023-05-08

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US (1) US20230174535A1 (enExample)
EP (1) EP3969442A4 (enExample)
JP (1) JP2022533939A (enExample)
CN (1) CN114127051A (enExample)
AU (1) AU2020278566A1 (enExample)
CA (1) CA3139161A1 (enExample)
WO (1) WO2020236524A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12441707B2 (en) 2019-12-30 2025-10-14 Tyra Biosciences, Inc. Indazole compounds
US11345681B1 (en) * 2020-06-05 2022-05-31 Kinnate Biopharma Inc. Inhibitors of fibroblast growth factor receptor kinases
CN116096707A (zh) * 2020-06-05 2023-05-09 金耐特生物制药公司 成纤维细胞生长因子受体激酶的抑制剂
KR20240119095A (ko) * 2021-12-08 2024-08-06 킨네이트 바이오파마 인크. Fgfr 저해제의 고체 상태 형태
WO2023107870A1 (en) * 2021-12-08 2023-06-15 Kinnate Biopharma Inc. Inhibitors of fibroblast growth factor receptor kinases
CN120344533A (zh) * 2022-11-22 2025-07-18 海思科医药集团股份有限公司 一种嘧啶衍生物及其在医药上的应用
AU2024301095A1 (en) * 2023-07-26 2026-03-12 Khora Spv 1, Llc Treatment of cancer with a cdk inhibitor

Citations (7)

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JP2007531754A (ja) * 2004-04-02 2007-11-08 オーエスアイ・ファーマスーティカルズ・インコーポレーテッド ６，６−二環置換されたヘテロ二環式タンパク質キナーゼ阻害剤
JP2009509961A (ja) * 2005-09-22 2009-03-12 ブリストル−マイヤーズ スクイブ カンパニー キナーゼモジュレーターとして有用な縮合へテロ環化合物
JP2009518303A (ja) * 2005-12-02 2009-05-07 バイエル・ヘルスケア・エルエルシー 過剰増殖性疾患および血管新生と関連する疾患を処置するために有用な置換された４−アミノ−ピロロトリアジン誘導体
WO2013108809A1 (ja) * 2012-01-19 2013-07-25 大鵬薬品工業株式会社 ３，５－二置換ベンゼンアルキニル化合物及びその塩
WO2016159327A1 (ja) * 2015-03-31 2016-10-06 大鵬薬品工業株式会社 ３，５－二置換ベンゼンアルキニル化合物の結晶
WO2018028438A1 (zh) * 2016-08-09 2018-02-15 南京天印健华医药科技有限公司 作为fgfr抑制剂的杂环化合物
WO2018121650A1 (zh) * 2016-12-29 2018-07-05 南京明德新药研发股份有限公司 Fgfr抑制剂

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GB0428082D0 (en) * 2004-12-22 2005-01-26 Welcome Trust The Ltd Therapeutic compounds
US7723336B2 (en) * 2005-09-22 2010-05-25 Bristol-Myers Squibb Company Fused heterocyclic compounds useful as kinase modulators
GB201503590D0 (en) * 2015-03-03 2015-04-15 Davis Adrian Topical formulation
US11221750B2 (en) * 2016-02-12 2022-01-11 Purdue Research Foundation Manipulating 3D virtual objects using hand-held controllers
US10685111B2 (en) * 2016-10-31 2020-06-16 Crowdstrike, Inc. File-modifying malware detection

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JP2007531754A (ja) * 2004-04-02 2007-11-08 オーエスアイ・ファーマスーティカルズ・インコーポレーテッド ６，６−二環置換されたヘテロ二環式タンパク質キナーゼ阻害剤
JP2009509961A (ja) * 2005-09-22 2009-03-12 ブリストル−マイヤーズ スクイブ カンパニー キナーゼモジュレーターとして有用な縮合へテロ環化合物
JP2009518303A (ja) * 2005-12-02 2009-05-07 バイエル・ヘルスケア・エルエルシー 過剰増殖性疾患および血管新生と関連する疾患を処置するために有用な置換された４−アミノ−ピロロトリアジン誘導体
WO2013108809A1 (ja) * 2012-01-19 2013-07-25 大鵬薬品工業株式会社 ３，５－二置換ベンゼンアルキニル化合物及びその塩
WO2016159327A1 (ja) * 2015-03-31 2016-10-06 大鵬薬品工業株式会社 ３，５－二置換ベンゼンアルキニル化合物の結晶
WO2018028438A1 (zh) * 2016-08-09 2018-02-15 南京天印健华医药科技有限公司 作为fgfr抑制剂的杂环化合物
WO2018121650A1 (zh) * 2016-12-29 2018-07-05 南京明德新药研发股份有限公司 Fgfr抑制剂

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C.G.WERMUTH編, 『最新 創薬化学 上巻』, JPN6014041942, 15 August 1998 (1998-08-15), pages 235 - 271, ISSN: 0005440429 *
野崎正勝 等, 創薬化学, vol. 第１版, JPN6012059719, 1995, pages 98 - 99, ISSN: 0005440430 *

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AU2020278566A1 (en) 2021-12-23
WO2020236524A1 (en) 2020-11-26
EP3969442A4 (en) 2023-08-02
EP3969442A1 (en) 2022-03-23
CN114127051A (zh) 2022-03-01
US20230174535A1 (en) 2023-06-08
CA3139161A1 (en) 2020-11-26

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