JP2022532998A5 - - Google Patents
Info
- Publication number
- JP2022532998A5 JP2022532998A5 JP2021563623A JP2021563623A JP2022532998A5 JP 2022532998 A5 JP2022532998 A5 JP 2022532998A5 JP 2021563623 A JP2021563623 A JP 2021563623A JP 2021563623 A JP2021563623 A JP 2021563623A JP 2022532998 A5 JP2022532998 A5 JP 2022532998A5
- Authority
- JP
- Japan
- Prior art keywords
- premrna
- target protein
- aic
- protein
- therapeutic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025087686A JP2025128180A (ja) | 2019-04-26 | 2025-05-27 | 選択的イントロンのスプライシングを調節するための方法及び組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962839572P | 2019-04-26 | 2019-04-26 | |
| US62/839,572 | 2019-04-26 | ||
| PCT/US2020/029953 WO2020219977A1 (en) | 2019-04-26 | 2020-04-24 | Methods and compositions for modulating splicing of alternative introns |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025087686A Division JP2025128180A (ja) | 2019-04-26 | 2025-05-27 | 選択的イントロンのスプライシングを調節するための方法及び組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022532998A JP2022532998A (ja) | 2022-07-21 |
| JP2022532998A5 true JP2022532998A5 (https=) | 2023-04-28 |
Family
ID=72941393
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021563623A Pending JP2022532998A (ja) | 2019-04-26 | 2020-04-24 | 選択的イントロンのスプライシングを調節するための方法及び組成物 |
| JP2025087686A Pending JP2025128180A (ja) | 2019-04-26 | 2025-05-27 | 選択的イントロンのスプライシングを調節するための方法及び組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025087686A Pending JP2025128180A (ja) | 2019-04-26 | 2025-05-27 | 選択的イントロンのスプライシングを調節するための方法及び組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220162599A1 (https=) |
| EP (1) | EP3959313A4 (https=) |
| JP (2) | JP2022532998A (https=) |
| KR (1) | KR20220019676A (https=) |
| CN (1) | CN114127286A (https=) |
| AU (1) | AU2020263581A1 (https=) |
| BR (1) | BR112021021384A2 (https=) |
| CA (1) | CA3134947A1 (https=) |
| MX (1) | MX2021013081A (https=) |
| WO (1) | WO2020219977A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2023348346A1 (en) * | 2022-09-30 | 2025-03-27 | Contera Pharma A/S | Antisense oligonucleotides for the treatment of canavan disease |
| CN121059628A (zh) * | 2024-06-03 | 2025-12-05 | 时夕(广州)生物科技有限公司 | 调控RNA剪接的向导agRNA |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060058253A1 (en) * | 2002-08-12 | 2006-03-16 | Benoit Chabot | Methods to reprogram splice site selection in pre-messenger rnas |
| EP2555778A4 (en) * | 2010-04-06 | 2014-05-21 | Alnylam Pharmaceuticals Inc | COMPOSITIONS AND METHODS FOR INHIBITING CD274 / PD-L1 GENE EXPRESSION |
| AU2015206603B9 (en) * | 2014-01-14 | 2019-07-18 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for identification, assessment, prevention, and treatment of melanoma using PD-L1 isoforms |
| AU2015327836B2 (en) * | 2014-10-03 | 2021-07-01 | Cold Spring Harbor Laboratory | Targeted augmentation of nuclear gene output |
| WO2017100587A1 (en) * | 2015-12-09 | 2017-06-15 | Alnylam Pharmaceuticals, Inc. | Polynucleotide agents targeting programmed cell death 1 ligand 1 (pd-l1) and methods of use thereof |
| WO2017106377A1 (en) * | 2015-12-14 | 2017-06-22 | Cold Spring Harbor Laboratory | Antisense oligomers for treatment of autosomal dominant mental retardation-5 and dravet syndrome |
| RU2747822C2 (ru) * | 2016-03-14 | 2021-05-14 | Ф. Хоффманн-Ля Рош Аг | Олигонуклеотиды для понижения экспрессии pd-l1 |
| SG10201705285SA (en) * | 2017-06-27 | 2019-01-30 | Agency Science Tech & Res | Antisense oligonucleotides |
-
2020
- 2020-04-24 MX MX2021013081A patent/MX2021013081A/es unknown
- 2020-04-24 JP JP2021563623A patent/JP2022532998A/ja active Pending
- 2020-04-24 CA CA3134947A patent/CA3134947A1/en active Pending
- 2020-04-24 CN CN202080040348.7A patent/CN114127286A/zh active Pending
- 2020-04-24 BR BR112021021384A patent/BR112021021384A2/pt unknown
- 2020-04-24 EP EP20795450.4A patent/EP3959313A4/en active Pending
- 2020-04-24 KR KR1020217038370A patent/KR20220019676A/ko active Pending
- 2020-04-24 WO PCT/US2020/029953 patent/WO2020219977A1/en not_active Ceased
- 2020-04-24 AU AU2020263581A patent/AU2020263581A1/en active Pending
-
2021
- 2021-11-03 US US17/518,337 patent/US20220162599A1/en active Pending
-
2025
- 2025-05-27 JP JP2025087686A patent/JP2025128180A/ja active Pending
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