JP2022532998A - 選択的イントロンのスプライシングを調節するための方法及び組成物 - Google Patents

選択的イントロンのスプライシングを調節するための方法及び組成物 Download PDF

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JP2022532998A
JP2022532998A JP2021563623A JP2021563623A JP2022532998A JP 2022532998 A JP2022532998 A JP 2022532998A JP 2021563623 A JP2021563623 A JP 2021563623A JP 2021563623 A JP2021563623 A JP 2021563623A JP 2022532998 A JP2022532998 A JP 2022532998A
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premrna
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target protein
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アズナレズ，イザベル
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ストーク セラピューティクス，インク．
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JP2021563623A 2019-04-26 2020-04-24 選択的イントロンのスプライシングを調節するための方法及び組成物 Pending JP2022532998A (ja)

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JP2025087686A JP2025128180A (ja) 2019-04-26 2025-05-27 選択的イントロンのスプライシングを調節するための方法及び組成物

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US201962839572P 2019-04-26 2019-04-26
US62/839,572 2019-04-26
PCT/US2020/029953 WO2020219977A1 (en) 2019-04-26 2020-04-24 Methods and compositions for modulating splicing of alternative introns

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JP2022532998A5 JP2022532998A5 (https=) 2023-04-28

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JP2025087686A Pending JP2025128180A (ja) 2019-04-26 2025-05-27 選択的イントロンのスプライシングを調節するための方法及び組成物

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US (1) US20220162599A1 (https=)
EP (1) EP3959313A4 (https=)
JP (2) JP2022532998A (https=)
KR (1) KR20220019676A (https=)
CN (1) CN114127286A (https=)
AU (1) AU2020263581A1 (https=)
BR (1) BR112021021384A2 (https=)
CA (1) CA3134947A1 (https=)
MX (1) MX2021013081A (https=)
WO (1) WO2020219977A1 (https=)

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AU2023348346A1 (en) * 2022-09-30 2025-03-27 Contera Pharma A/S Antisense oligonucleotides for the treatment of canavan disease
CN121059628A (zh) * 2024-06-03 2025-12-05 时夕(广州)生物科技有限公司 调控RNA剪接的向导agRNA

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2019004939A1 (en) * 2017-06-27 2019-01-03 Agency For Science, Technology And Research ANTISENSE OLIGONUCLEOTIDES FOR MODULATING THE FUNCTION OF A LYMPHOCYTE T

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US20060058253A1 (en) * 2002-08-12 2006-03-16 Benoit Chabot Methods to reprogram splice site selection in pre-messenger rnas
EP2555778A4 (en) * 2010-04-06 2014-05-21 Alnylam Pharmaceuticals Inc COMPOSITIONS AND METHODS FOR INHIBITING CD274 / PD-L1 GENE EXPRESSION
AU2015206603B9 (en) * 2014-01-14 2019-07-18 Dana-Farber Cancer Institute, Inc. Compositions and methods for identification, assessment, prevention, and treatment of melanoma using PD-L1 isoforms
AU2015327836B2 (en) * 2014-10-03 2021-07-01 Cold Spring Harbor Laboratory Targeted augmentation of nuclear gene output
WO2017100587A1 (en) * 2015-12-09 2017-06-15 Alnylam Pharmaceuticals, Inc. Polynucleotide agents targeting programmed cell death 1 ligand 1 (pd-l1) and methods of use thereof
WO2017106377A1 (en) * 2015-12-14 2017-06-22 Cold Spring Harbor Laboratory Antisense oligomers for treatment of autosomal dominant mental retardation-5 and dravet syndrome
RU2747822C2 (ru) * 2016-03-14 2021-05-14 Ф. Хоффманн-Ля Рош Аг Олигонуклеотиды для понижения экспрессии pd-l1

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019004939A1 (en) * 2017-06-27 2019-01-03 Agency For Science, Technology And Research ANTISENSE OLIGONUCLEOTIDES FOR MODULATING THE FUNCTION OF A LYMPHOCYTE T

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
NAT. REV. GENET., vol. vol.17, issue 7, JPN6024017928, 2016, pages 407 - 421, ISSN: 0005511059 *
NUCLEIC ACIDS RES., vol. 44, no. 14, JPN6024017927, 2016, pages 6549 - 6563, ISSN: 0005511060 *
OLIGONUCLEOTIDES, vol. 19, no. 1, JPN6024017926, 2009, pages 1 - 13, ISSN: 0005511061 *

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EP3959313A4 (en) 2023-09-27
BR112021021384A2 (pt) 2021-12-21
US20220162599A1 (en) 2022-05-26
CN114127286A (zh) 2022-03-01
KR20220019676A (ko) 2022-02-17
AU2020263581A1 (en) 2021-12-16
MX2021013081A (es) 2021-12-10
WO2020219977A1 (en) 2020-10-29
EP3959313A1 (en) 2022-03-02
JP2025128180A (ja) 2025-09-02
CA3134947A1 (en) 2020-10-29

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