JP2022528693A - アッセイ精度及び信頼性の向上 - Google Patents

アッセイ精度及び信頼性の向上 Download PDF

Info

Publication number
JP2022528693A
JP2022528693A JP2021559273A JP2021559273A JP2022528693A JP 2022528693 A JP2022528693 A JP 2022528693A JP 2021559273 A JP2021559273 A JP 2021559273A JP 2021559273 A JP2021559273 A JP 2021559273A JP 2022528693 A JP2022528693 A JP 2022528693A
Authority
JP
Japan
Prior art keywords
sample
image
assay
card
monitoring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021559273A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022528693A5 (https=
Inventor
スティーブン ワイ. チョウ
ウー チョウ
シン リ
ホンビン リ
ユエチェン チャン
ミンカン ウー
ウェイ ディン
ジュン ティアン
Original Assignee
エッセンリックス コーポレーション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2019/046971 external-priority patent/WO2020055543A1/en
Priority claimed from PCT/US2019/048678 external-priority patent/WO2020047177A1/en
Application filed by エッセンリックス コーポレーション filed Critical エッセンリックス コーポレーション
Publication of JP2022528693A publication Critical patent/JP2022528693A/ja
Publication of JP2022528693A5 publication Critical patent/JP2022528693A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429Signal processing
    • G01N15/1433Signal processing using image recognition
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274Calibration, base line adjustment, drift correction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65Raman scattering
    • G01N21/658Raman scattering enhancement Raman, e.g. surface plasmons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/88Investigating the presence of flaws or contamination
    • G01N21/8851Scan or image signal processing specially adapted therefor, e.g. for scan signal adjustment, for detecting different kinds of defects, for compensating for structures, markings, edges
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N20/00Machine learning
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/04Architecture, e.g. interconnection topology
    • G06N3/0464Convolutional networks [CNN, ConvNet]
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/08Learning methods
    • G06N3/09Supervised learning
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/40Analysis of texture
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/60Analysis of geometric attributes
    • G06T7/62Analysis of geometric attributes of area, perimeter, diameter or volume
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N2021/0106General arrangement of respective parts
    • G01N2021/0112Apparatus in one mechanical, optical or electronic block
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/88Investigating the presence of flaws or contamination
    • G01N21/8851Scan or image signal processing specially adapted therefor, e.g. for scan signal adjustment, for detecting different kinds of defects, for compensating for structures, markings, edges
    • G01N2021/8887Scan or image signal processing specially adapted therefor, e.g. for scan signal adjustment, for detecting different kinds of defects, for compensating for structures, markings, edges based on image processing techniques
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/04Architecture, e.g. interconnection topology
    • G06N3/045Combinations of networks
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10056Microscopic image
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30024Cell structures in vitro; Tissue sections in vitro
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30204Marker

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Software Systems (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Mathematical Physics (AREA)
  • General Engineering & Computer Science (AREA)
  • Computing Systems (AREA)
  • Evolutionary Computation (AREA)
  • Data Mining & Analysis (AREA)
  • Artificial Intelligence (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Signal Processing (AREA)
  • Molecular Biology (AREA)
  • Computational Linguistics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Quality & Reliability (AREA)
  • Geometry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2021559273A 2019-04-05 2020-04-06 アッセイ精度及び信頼性の向上 Pending JP2022528693A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962830311P 2019-04-05 2019-04-05
US62/830,311 2019-04-05
USPCT/US2019/046971 2019-08-16
PCT/US2019/046971 WO2020055543A1 (en) 2018-08-16 2019-08-16 Image-based assay using intelligent monitoring structures
PCT/US2019/048678 WO2020047177A1 (en) 2018-08-28 2019-08-28 Assay accuracy improvement
USPCT/US2019/048678 2019-08-28
PCT/US2020/026959 WO2020206464A1 (en) 2019-04-05 2020-04-06 Assay accuracy and reliability improvement

Publications (2)

Publication Number Publication Date
JP2022528693A true JP2022528693A (ja) 2022-06-15
JP2022528693A5 JP2022528693A5 (https=) 2023-04-07

Family

ID=72667405

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021559273A Pending JP2022528693A (ja) 2019-04-05 2020-04-06 アッセイ精度及び信頼性の向上

Country Status (5)

Country Link
US (3) US11733151B2 (https=)
EP (1) EP3948226A4 (https=)
JP (1) JP2022528693A (https=)
CN (2) CN120801199A (https=)
WO (1) WO2020206464A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7167315B2 (ja) * 2019-03-29 2022-11-08 富士フイルム株式会社 画像処理装置、画像処理装置の作動方法、および画像処理装置の作動プログラム
US11486550B2 (en) * 2019-05-22 2022-11-01 Nichia Corporation Method for producing wavelength conversion sintered body
US11762283B2 (en) * 2019-12-13 2023-09-19 Synopsys, Inc. Inverse lithography and machine learning for mask synthesis
LU101763B1 (en) * 2020-05-04 2021-11-05 Microsoft Technology Licensing Llc Microsegment secure speech transcription
CN112307986B (zh) * 2020-11-03 2022-02-08 华北电力大学 一种利用高斯梯度的负荷开关事件检测方法和系统
CN114624164B (zh) * 2020-12-14 2026-01-30 深圳迈瑞生物医疗电子股份有限公司 尿液有形成分分析系统及其方法
CN112687381B (zh) * 2020-12-25 2025-03-25 邦奇(河南)生物技术有限公司 一种医疗用院内感染监测系统
CN114693531B (zh) * 2020-12-28 2024-12-20 富泰华工业(深圳)有限公司 图像对比方法及相关设备
WO2022204611A1 (en) * 2021-03-26 2022-09-29 Essenlix Corporation Cells and other bio-entity analysis and counting
JP7719206B2 (ja) * 2021-04-02 2025-08-05 イルミナ インコーポレイテッド 配列決定のためのヌクレオチド-試料スライド内の泡を検出するための機械学習モデル
EP4437499A4 (en) * 2021-11-23 2025-08-27 Tufts College SYSTEMS, METHODS, AND PROGRAM PRODUCTS FOR DETECTION AND IDENTIFICATION OF DEFECTS USING ARTIFICIAL INTELLIGENCE ANALYSIS OF MULTIDIMENSIONAL INFORMATION DATA
CN115019077A (zh) * 2022-08-09 2022-09-06 江苏思伽循环科技有限公司 一种废旧电池回收工艺中的摇床分选机识别及控制方法
CN115661470B (zh) * 2022-10-28 2026-04-21 军事科学院系统工程研究院卫勤保障技术研究所 一种基于三维卷积神经网络的彩色偏振图像的去噪方法
CN116797646B (zh) * 2023-03-13 2025-07-15 中铁二院工程集团有限责任公司 一种基于三维图像的危岩体体积计算方法
CN121195517A (zh) * 2023-05-26 2025-12-23 斯伦贝谢技术有限公司 用于连续数字图像校准的系统、设备和方法

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000316120A (ja) * 1999-03-03 2000-11-14 Denso Corp 全焦点撮像装置
JP2001194368A (ja) * 1999-12-17 2001-07-19 Bayer Corp 液体試料中の分析対象物の検定のための改良された試験片
JP2002520617A (ja) * 1998-07-14 2002-07-09 コザート バイオサイエンス リミテッド スクリーニングデバイスおよびイムノアッセイテストのスクリーニング法
EP2196117A1 (de) * 2008-12-10 2010-06-16 Tchibo GmbH Brühmaschine
US20160080548A1 (en) * 2013-01-21 2016-03-17 Cornell University Smartphone-Based Apparatus and Method
WO2017178417A1 (en) * 2016-04-15 2017-10-19 University College Of Southeast Norway On-diaper body fluid screening device
JP2018517209A (ja) * 2015-05-28 2018-06-28 トキタエ エルエルシー 画像分析システムおよび関連する方法
WO2018148471A2 (en) * 2017-02-08 2018-08-16 Essenlix Corporation Optics, device, and system for assaying
JP2018529074A (ja) * 2015-05-26 2018-10-04 ベンタナ メディカル システムズ, インコーポレイテッド イン・サイチュー・ハイブリダイゼーションおよび免疫組織化学のための染色品質評価方法およびシステム
JP2018529982A (ja) * 2015-08-10 2018-10-11 エッセンリックス コーポレーション ステップが簡略化され、試料が少なく、スピードアップし、使いやすい、生化学的/化学的なアッセイ装置及び方法
WO2019044424A1 (ja) * 2017-08-29 2019-03-07 富士フイルム株式会社 撮影制御装置、方法およびプログラム

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100388313C (zh) * 2003-02-05 2008-05-14 皇家飞利浦电子股份有限公司 定量分析精度指示
FR2894685A3 (fr) * 2005-12-09 2007-06-15 6115187 Canada Inc Procede et dispositif d'identification et de calibration d'optiques panoramiques
GB201105474D0 (en) * 2011-03-31 2011-05-18 Albagaia Ltd Testing apparatus
WO2012147021A1 (en) * 2011-04-28 2012-11-01 Koninklijke Philips Electronics N.V. Evaluating assays which optical inhomogeneities
CN102393376A (zh) * 2011-10-14 2012-03-28 上海海洋大学 基于支持向量回归的鱼丸多组分含量检测的近红外光谱法
US9695981B2 (en) * 2012-04-20 2017-07-04 Honeywell International Inc. Image recognition for personal protective equipment compliance enforcement in work areas
KR102090776B1 (ko) * 2012-07-25 2020-03-18 테라노스, 인코포레이티드 생체시료의 이미지 분석 및 측정
EP2883037B1 (en) * 2012-08-08 2023-06-07 Healthy.io Ltd. Method and apparatus for performing and quantifying color changes induced by specific concentrations of biological analytes in an automatically calibrated environment
US10466236B2 (en) 2013-03-29 2019-11-05 Nima Labs, Inc. System and method for detecting target substances
US20150185208A1 (en) 2013-10-11 2015-07-02 Immunetics, Inc. Led assay reader with touchscreen control and barcode sample id
CN106068449A (zh) * 2014-03-05 2016-11-02 思勘度股份有限公司 通过量化和解释颜色的分析物浓度
JP2016058465A (ja) * 2014-09-08 2016-04-21 株式会社日立ハイテクノロジーズ 欠陥定量化方法、欠陥定量化装置、および欠陥評価値表示装置
HK1243207A1 (zh) * 2014-10-17 2018-07-06 Cireca Theranostics, Llc 用於分类生物样本﹑包括分析的优化和相关性的使用的方法和系统
MX392709B (es) * 2015-09-14 2025-03-24 Essenlix Corp Dispositivo y sistema para recolectar y analizar condensado de vapor, particularmente condensado de exhalación de la respiración y un método para usarlo.
CN110312473B (zh) * 2016-12-21 2023-04-07 艾森利克斯公司 用于认证样本的装置和方法及其使用
CN106932359A (zh) * 2017-03-02 2017-07-07 兰州大学 一种基于近红外光谱的苹果分类方法
US10552663B2 (en) * 2017-05-02 2020-02-04 Techcyte, Inc. Machine learning classification and training for digital microscopy cytology images
WO2018208820A1 (en) * 2017-05-08 2018-11-15 Biological Dynamics, Inc. Methods and systems for analyte information processing
JP7455757B2 (ja) * 2018-04-13 2024-03-26 フリーノーム・ホールディングス・インコーポレイテッド 生体試料の多検体アッセイのための機械学習実装
WO2020055543A1 (en) * 2018-08-16 2020-03-19 Essenlix Corporation Image-based assay using intelligent monitoring structures
CN113227755B (zh) * 2018-08-28 2025-06-27 上海宜晟生物科技有限公司 测定准确度改善

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002520617A (ja) * 1998-07-14 2002-07-09 コザート バイオサイエンス リミテッド スクリーニングデバイスおよびイムノアッセイテストのスクリーニング法
JP2000316120A (ja) * 1999-03-03 2000-11-14 Denso Corp 全焦点撮像装置
JP2001194368A (ja) * 1999-12-17 2001-07-19 Bayer Corp 液体試料中の分析対象物の検定のための改良された試験片
EP2196117A1 (de) * 2008-12-10 2010-06-16 Tchibo GmbH Brühmaschine
US20160080548A1 (en) * 2013-01-21 2016-03-17 Cornell University Smartphone-Based Apparatus and Method
JP2018529074A (ja) * 2015-05-26 2018-10-04 ベンタナ メディカル システムズ, インコーポレイテッド イン・サイチュー・ハイブリダイゼーションおよび免疫組織化学のための染色品質評価方法およびシステム
JP2018517209A (ja) * 2015-05-28 2018-06-28 トキタエ エルエルシー 画像分析システムおよび関連する方法
JP2018529982A (ja) * 2015-08-10 2018-10-11 エッセンリックス コーポレーション ステップが簡略化され、試料が少なく、スピードアップし、使いやすい、生化学的/化学的なアッセイ装置及び方法
WO2017178417A1 (en) * 2016-04-15 2017-10-19 University College Of Southeast Norway On-diaper body fluid screening device
WO2018148471A2 (en) * 2017-02-08 2018-08-16 Essenlix Corporation Optics, device, and system for assaying
WO2019044424A1 (ja) * 2017-08-29 2019-03-07 富士フイルム株式会社 撮影制御装置、方法およびプログラム

Also Published As

Publication number Publication date
US11733151B2 (en) 2023-08-22
US12007320B2 (en) 2024-06-11
CN120801199A (zh) 2025-10-17
CN114341619A (zh) 2022-04-12
US20230341315A1 (en) 2023-10-26
EP3948226A4 (en) 2023-09-06
EP3948226A1 (en) 2022-02-09
CN114341619B (zh) 2025-04-11
US20210312621A1 (en) 2021-10-07
US20250116593A1 (en) 2025-04-10
WO2020206464A1 (en) 2020-10-08

Similar Documents

Publication Publication Date Title
US12007320B2 (en) Assay detection, accuracy and reliability improvement
US20230324278A1 (en) Assay accuracy improvement
US20240035954A1 (en) Image-Based Assay Performance Improvement
CN113227754B (zh) 使用智能监测结构的基于图像的测定
DK2973397T3 (en) Tissue-object-based machine learning system for automated assessment of digital whole-slide glass
CN104094118B (zh) 通过显微图像自动识别全血样品中血小板的方法和设备
US20230408534A1 (en) Assay Error Reduction
JP6594294B2 (ja) 顕微鏡画像の画像品質評価
US20140139625A1 (en) Method and system for detecting and/or classifying cancerous cells in a cell sample
JP6986083B2 (ja) レンズレス撮像によるサンプル内の粒子の計数方法
JP7282894B2 (ja) 粒子定量装置
CN114152557B (zh) 基于图像分析的血细胞计数方法和系统
TWI755755B (zh) 用於測試生物樣本的裝置
JP2026512395A (ja) 血液塗抹物の単層の検出
WO2026029981A1 (en) Deep learning-based automated quality control tool for identifying out-of-focus regions in microscopic imaging

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230329

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20230329

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20230620

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20240116

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20240208

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20240528

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20241203