JP2022527176A5 - - Google Patents

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Publication number
JP2022527176A5
JP2022527176A5 JP2021557633A JP2021557633A JP2022527176A5 JP 2022527176 A5 JP2022527176 A5 JP 2022527176A5 JP 2021557633 A JP2021557633 A JP 2021557633A JP 2021557633 A JP2021557633 A JP 2021557633A JP 2022527176 A5 JP2022527176 A5 JP 2022527176A5
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JP
Japan
Prior art keywords
therapeutic agent
compound
independently
mannose
binding
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JP2021557633A
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English (en)
Japanese (ja)
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JP2022527176A (ja
JP7665206B2 (ja
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Priority claimed from PCT/US2020/025326 external-priority patent/WO2020198622A1/en
Publication of JP2022527176A publication Critical patent/JP2022527176A/ja
Publication of JP2022527176A5 publication Critical patent/JP2022527176A5/ja
Application granted granted Critical
Publication of JP7665206B2 publication Critical patent/JP7665206B2/ja
Active legal-status Critical Current
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JP2021557633A 2019-03-27 2020-03-27 マクロファージの表現型を改変するための組成物および方法 Active JP7665206B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962824853P 2019-03-27 2019-03-27
US62/824,853 2019-03-27
PCT/US2020/025326 WO2020198622A1 (en) 2019-03-27 2020-03-27 Compositions and methods for altering macrophage phenotype

Publications (3)

Publication Number Publication Date
JP2022527176A JP2022527176A (ja) 2022-05-31
JP2022527176A5 true JP2022527176A5 (https=) 2023-04-03
JP7665206B2 JP7665206B2 (ja) 2025-04-21

Family

ID=72606452

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021557633A Active JP7665206B2 (ja) 2019-03-27 2020-03-27 マクロファージの表現型を改変するための組成物および方法

Country Status (8)

Country Link
US (3) US11590236B2 (https=)
EP (1) EP3946473A4 (https=)
JP (1) JP7665206B2 (https=)
BR (1) BR112021019187A2 (https=)
CA (1) CA3134974A1 (https=)
IL (1) IL286678B2 (https=)
MX (1) MX2021011703A (https=)
WO (1) WO2020198622A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021019187A2 (pt) * 2019-03-27 2021-12-21 Navidea Biopharmaceuticals Inc Método para repolarização de um macrófago associado a tumor de m2 a m1, e, composto para repolarização de um macrófago associado a tumor de m2 a m1
US20210052639A1 (en) * 2019-08-19 2021-02-25 Navidea Biopharmaceuticals, Inc. Compositions and related methods for the ablation of m2 macrophages and myeloid derived suppressor cells
JP2025517414A (ja) * 2022-05-20 2025-06-05 ナビディア、バイオファーマスーティカルズ、インコーポレイテッド 分解性リンカーを介して新規ビスホスホネート薬物ペイロードを担持するcd206標的化薬物送達ビヒクル
WO2024076988A2 (en) * 2022-10-03 2024-04-11 Navidea Biopharmaceuticals, Inc. Amide linkages of sugar moieties to amine terminated leashes attached to carbohydrate polymers
CN116259757B (zh) * 2023-02-06 2026-01-30 西北大学 MXene改性的金属离子预嵌入V5O12·6H2O复合材料及其制备方法和应用

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
US6218367B1 (en) * 1998-09-15 2001-04-17 Organomed Corporation Paclitaxel-carbohydrate conjugates: design, synthesis and biological evaluations
CN101801462A (zh) 2007-07-13 2010-08-11 健泰科生物技术公司 用于癌症、炎性病症和自身免疫性病症的治疗和诊断
WO2013057281A2 (en) 2011-10-21 2013-04-25 Transgene Sa Modulation of macrophage activation
CN114377143A (zh) * 2013-07-22 2022-04-22 康德乐健康414有限责任公司 用于诊断和治疗与表达cd206的细胞相关的病症的组合物、方法和药盒
CA2955438C (en) 2014-07-17 2024-07-02 Ohio State Innovation Foundation DEXTRANE CONJUGATES TO TARGET MACROPHAGES AND OTHER CELLS EXPRESSING THE D-MANBOSE BINDING TYPE C LECTIN RECEPTOR
US10806803B2 (en) * 2014-07-17 2020-10-20 Ohio State Innovation Foundation Compositions for targeting macrophages and other CD206 high expressing cells and methods of treating and diagnosis
WO2016011419A1 (en) * 2014-07-17 2016-01-21 Ohio State Innovation Foundation Compositions for targeting macrophages and other cd206 high expressing cells and methods of treating and diagnosis
WO2016118188A1 (en) * 2015-01-21 2016-07-28 Navidea Biopharmaceuticals, Inc. Compositions for targeting macrophages and other mannose-binding c-type lectin receptor high expressing cells
MX2019004029A (es) * 2016-10-07 2019-09-27 Navidea Biopharmaceuticals Inc Compuestos y metodos para diagnosis y tratamiento de infecciones virales.
EP3522899A4 (en) * 2016-10-07 2020-05-06 Navidea Biopharmaceuticals, Inc. Compounds and compositions for treating leishmaniasis and methods of diagnosis and treating using same
CA3064277A1 (en) 2017-05-19 2018-11-22 Navidea Biopharmaceuticals, Inc. Cd206+ macrophage-specific molecular imaging probe compositions and methods and the noninvasive quantification of arterial wall macrophage infiltration in humans
US20210000920A1 (en) * 2017-12-22 2021-01-07 Atossa Therapeutics, Inc. Intraductal methods of treatment of breast disorders
BR112021019187A2 (pt) * 2019-03-27 2021-12-21 Navidea Biopharmaceuticals Inc Método para repolarização de um macrófago associado a tumor de m2 a m1, e, composto para repolarização de um macrófago associado a tumor de m2 a m1
US20210052639A1 (en) * 2019-08-19 2021-02-25 Navidea Biopharmaceuticals, Inc. Compositions and related methods for the ablation of m2 macrophages and myeloid derived suppressor cells

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