JP2021505540A5 - - Google Patents
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- Publication number
- JP2021505540A5 JP2021505540A5 JP2020529281A JP2020529281A JP2021505540A5 JP 2021505540 A5 JP2021505540 A5 JP 2021505540A5 JP 2020529281 A JP2020529281 A JP 2020529281A JP 2020529281 A JP2020529281 A JP 2020529281A JP 2021505540 A5 JP2021505540 A5 JP 2021505540A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- antibody
- binding fragment
- pharmaceutical composition
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023173950A JP2024001187A (ja) | 2017-12-01 | 2023-10-06 | 乳がんの処置のためのヒト化抗ｌｉｖ１抗体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762593660P | 2017-12-01 | 2017-12-01 | |
| US62/593,660 | 2017-12-01 | ||
| PCT/US2018/063425 WO2019109007A1 (en) | 2017-12-01 | 2018-11-30 | Humanized anti-liv1 antibodies for the treatment of breast cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023173950A Division JP2024001187A (ja) | 2017-12-01 | 2023-10-06 | 乳がんの処置のためのヒト化抗ｌｉｖ１抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021505540A JP2021505540A (ja) | 2021-02-18 |
| JP2021505540A5 true JP2021505540A5 (https=) | 2022-01-11 |
Family
ID=64746653
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020529281A Pending JP2021505540A (ja) | 2017-12-01 | 2018-11-30 | 乳がんの処置のためのヒト化抗ｌｉｖ１抗体 |
| JP2023173950A Withdrawn JP2024001187A (ja) | 2017-12-01 | 2023-10-06 | 乳がんの処置のためのヒト化抗ｌｉｖ１抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023173950A Withdrawn JP2024001187A (ja) | 2017-12-01 | 2023-10-06 | 乳がんの処置のためのヒト化抗ｌｉｖ１抗体 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20200283540A1 (https=) |
| EP (1) | EP3717518A1 (https=) |
| JP (2) | JP2021505540A (https=) |
| KR (1) | KR20200090838A (https=) |
| CN (1) | CN111757892A (https=) |
| AU (1) | AU2018375182A1 (https=) |
| BR (1) | BR112020010937A2 (https=) |
| CA (1) | CA3084495A1 (https=) |
| EA (1) | EA202091360A1 (https=) |
| IL (1) | IL274766A (https=) |
| MA (1) | MA50943A (https=) |
| MX (1) | MX2020005640A (https=) |
| SG (1) | SG11202004751TA (https=) |
| WO (1) | WO2019109007A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6105481B2 (ja) | 2010-12-06 | 2017-03-29 | シアトル ジェネティクス，インコーポレーテッド | Ｌｉｖ−１に対するヒト化抗体および癌治療のためのその使用 |
| MA45324A (fr) * | 2016-03-15 | 2019-01-23 | Seattle Genetics Inc | Polythérapie utilisant un adc-liv1 et un agent chimiothérapeutique |
| TWI851577B (zh) | 2018-06-07 | 2024-08-11 | 美商思進公司 | 喜樹鹼結合物 |
| GB201908208D0 (en) * | 2019-06-10 | 2019-07-24 | Univ College Cardiff Consultants Ltd | An anti-mitotic agent |
| BR112022001045A2 (pt) * | 2019-07-22 | 2022-07-19 | Seagen Inc | Método para tratar um indivíduo com ou em risco de desenvolver um câncer associado a liv1, e, kit |
| BR112022011268A2 (pt) * | 2019-12-09 | 2022-09-06 | Seagen Inc | Terapia de combinação com antagonista de liv1-adc e pd1 |
| AU2022238571A1 (en) | 2021-03-18 | 2023-09-14 | Seagen Inc. | Selective drug release from internalized conjugates of biologically active compounds |
| CN119317646A (zh) * | 2022-06-16 | 2025-01-14 | 山东博安生物技术股份有限公司 | 抗liv-1抗体及其药物偶联物 |
| AU2024218701A1 (en) | 2023-02-07 | 2025-08-21 | LaNova Medicines Limited | Antibodies targeting liv-1 and uses thereof |
| JP2026509871A (ja) * | 2023-03-15 | 2026-03-25 | 浙江博鋭生物製薬有限公司 | 抗ｌｉｖ－１抗体及び抗ｌｉｖ－１抗体薬物複合体並びにその薬物的使用 |
| WO2025146137A1 (zh) * | 2024-01-05 | 2025-07-10 | 海南先声再明医药股份有限公司 | 抗liv-1抗体药物偶联物及其用途 |
| CN120040587B (zh) * | 2025-04-27 | 2025-08-08 | 上海宏成药业有限公司 | 抗liv-1抗体或其抗原结合片段及其用途 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US4880935A (en) | 1986-07-11 | 1989-11-14 | Icrf (Patents) Limited | Heterobifunctional linking agents derived from N-succinimido-dithio-alpha methyl-methylene-benzoates |
| IL106992A (en) | 1988-02-11 | 1994-06-24 | Bristol Myers Squibb Co | Acylhydrazone derivatives of anthracycline and methods for their preparation |
| EP0368684B2 (en) | 1988-11-11 | 2004-09-29 | Medical Research Council | Cloning immunoglobulin variable domain sequences. |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| US5622929A (en) | 1992-01-23 | 1997-04-22 | Bristol-Myers Squibb Company | Thioether conjugates |
| ATE234635T1 (de) | 1995-12-22 | 2003-04-15 | Bristol Myers Squibb Co | Verzweigte hydrazongruppen enthaltende kuppler |
| MXPA05000511A (es) | 2001-07-12 | 2005-09-30 | Jefferson Foote | Anticuepros super humanizados. |
| SI1545613T1 (sl) | 2002-07-31 | 2011-11-30 | Seattle Genetics Inc | Avristatinski konjugati in njihova uporaba za zdravljenje raka avtoimunske bolezni ali infekcijskebolezni |
| WO2004067564A2 (en) | 2003-01-29 | 2004-08-12 | Protein Design Labs, Inc. | Compositions against cancer antigen liv-1 and uses thereof |
| US7498298B2 (en) | 2003-11-06 | 2009-03-03 | Seattle Genetics, Inc. | Monomethylvaline compounds capable of conjugation to ligands |
| JP5171621B2 (ja) | 2005-07-07 | 2013-03-27 | シアトル ジェネティックス， インコーポレイテッド | フェニルアラニン側鎖修飾をｃ末端に有するモノメチルバリン化合物 |
| US8871720B2 (en) | 2005-07-07 | 2014-10-28 | Seattle Genetics, Inc. | Monomethylvaline compounds having phenylalanine carboxy modifications at the C-terminus |
| CN101622273A (zh) * | 2006-04-13 | 2010-01-06 | 诺瓦提斯疫苗和诊断公司 | 治疗、诊断或检测与liv-1过量表达相关的癌症的方法 |
| RU2476441C2 (ru) | 2007-10-19 | 2013-02-27 | Сиэтл Дженетикс, Инк. | Cd19-связывающие средства и их применение |
| JP6105481B2 (ja) | 2010-12-06 | 2017-03-29 | シアトル ジェネティクス，インコーポレーテッド | Ｌｉｖ−１に対するヒト化抗体および癌治療のためのその使用 |
| CA2873111A1 (en) * | 2012-05-11 | 2013-11-14 | Merrimack Pharmaceuticals, Inc. | Dosage and administration of bispecific scfv conjugates in combination with anti-cancer therapeutics |
| US9492566B2 (en) * | 2012-12-13 | 2016-11-15 | Immunomedics, Inc. | Antibody-drug conjugates and uses thereof |
| WO2015175533A2 (en) * | 2014-05-13 | 2015-11-19 | Immunogen, Inc. | Anti-cd37 immunoconjugate dosing regimens |
| MA45324A (fr) * | 2016-03-15 | 2019-01-23 | Seattle Genetics Inc | Polythérapie utilisant un adc-liv1 et un agent chimiothérapeutique |
-
2018
- 2018-11-30 MA MA050943A patent/MA50943A/fr unknown
- 2018-11-30 SG SG11202004751TA patent/SG11202004751TA/en unknown
- 2018-11-30 BR BR112020010937-1A patent/BR112020010937A2/pt not_active IP Right Cessation
- 2018-11-30 JP JP2020529281A patent/JP2021505540A/ja active Pending
- 2018-11-30 CA CA3084495A patent/CA3084495A1/en active Pending
- 2018-11-30 AU AU2018375182A patent/AU2018375182A1/en not_active Abandoned
- 2018-11-30 CN CN201880077514.3A patent/CN111757892A/zh active Pending
- 2018-11-30 US US16/768,020 patent/US20200283540A1/en not_active Abandoned
- 2018-11-30 WO PCT/US2018/063425 patent/WO2019109007A1/en not_active Ceased
- 2018-11-30 KR KR1020207017651A patent/KR20200090838A/ko not_active Abandoned
- 2018-11-30 EP EP18822563.5A patent/EP3717518A1/en not_active Withdrawn
- 2018-11-30 EA EA202091360A patent/EA202091360A1/ru unknown
- 2018-11-30 MX MX2020005640A patent/MX2020005640A/es unknown
-
2020
- 2020-05-19 IL IL274766A patent/IL274766A/en unknown
-
2023
- 2023-03-07 US US18/179,560 patent/US20240076402A1/en not_active Abandoned
- 2023-10-06 JP JP2023173950A patent/JP2024001187A/ja not_active Withdrawn
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