JP2022525400A5 - - Google Patents

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Publication number
JP2022525400A5
JP2022525400A5 JP2021555170A JP2021555170A JP2022525400A5 JP 2022525400 A5 JP2022525400 A5 JP 2022525400A5 JP 2021555170 A JP2021555170 A JP 2021555170A JP 2021555170 A JP2021555170 A JP 2021555170A JP 2022525400 A5 JP2022525400 A5 JP 2022525400A5
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JP
Japan
Prior art keywords
target portion
unbound target
salt
unbound
bound
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021555170A
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English (en)
Japanese (ja)
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JP2022525400A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/022130 external-priority patent/WO2020185917A1/en
Publication of JP2022525400A publication Critical patent/JP2022525400A/ja
Publication of JP2022525400A5 publication Critical patent/JP2022525400A5/ja
Pending legal-status Critical Current

Links

JP2021555170A 2019-03-13 2020-03-11 フルオレセインエーテルリン脂質またはフルオレセインエーテルリン脂質前駆体と併用した抗フルオレセインcar t細胞に対する拮抗薬としてのフルオレセインナトリウム Pending JP2022525400A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962818030P 2019-03-13 2019-03-13
US62/818,030 2019-03-13
PCT/US2020/022130 WO2020185917A1 (en) 2019-03-13 2020-03-11 Sodium fluorescein as a reversal agent for an anti-fluorescein car t cells and fluorescein-phospholipid-ethers or profluorescein-phospholipid-ethers

Publications (2)

Publication Number Publication Date
JP2022525400A JP2022525400A (ja) 2022-05-13
JP2022525400A5 true JP2022525400A5 (https=) 2023-03-14

Family

ID=72426940

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021555170A Pending JP2022525400A (ja) 2019-03-13 2020-03-11 フルオレセインエーテルリン脂質またはフルオレセインエーテルリン脂質前駆体と併用した抗フルオレセインcar t細胞に対する拮抗薬としてのフルオレセインナトリウム

Country Status (6)

Country Link
US (1) US20220125841A1 (https=)
EP (1) EP3937975A4 (https=)
JP (1) JP2022525400A (https=)
AU (1) AU2020237097A1 (https=)
CA (1) CA3140210A1 (https=)
WO (1) WO2020185917A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12312416B2 (en) * 2018-02-06 2025-05-27 Seattle Children's Hospital Fluorescein-specific cars exhibiting optimal t cell function against FL-PLE labelled tumors
CN115210252A (zh) 2020-02-04 2022-10-18 西雅图儿童医院(Dba西雅图儿童研究所) 抗二硝基苯酚的嵌合抗原受体
EP4228660A4 (en) * 2020-10-14 2025-02-26 Georgia Tech Research Corporation Synthetic antigens as chimeric antigen receptor (car) ligands and uses thereof
WO2023224715A1 (en) * 2022-05-19 2023-11-23 Massachusetts Institute Of Technology Car cells targeting an inserted ligand

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4282419A1 (en) * 2012-12-20 2023-11-29 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
CA2968145C (en) * 2014-11-17 2023-06-27 Cellectar Biosciences, Inc. Phospholipid ether analogs as cancer-targeting drug vehicles
AU2016274989A1 (en) * 2015-06-12 2017-11-02 Immunomedics, Inc. Disease therapy with chimeric antigen receptor (car) constructs and t cells (car-t) or nk cells (car-nk) expressing car constructs
US11408005B2 (en) * 2016-12-12 2022-08-09 Seattle Children's Hospital Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells
US11649288B2 (en) * 2017-02-07 2023-05-16 Seattle Children's Hospital Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents
WO2018160622A1 (en) * 2017-02-28 2018-09-07 Endocyte, Inc. Compositions and methods for car t cell therapy

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