JP2022525102A - 心臓トロポニン活性化因子の多形 - Google Patents

心臓トロポニン活性化因子の多形 Download PDF

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Publication number
JP2022525102A
JP2022525102A JP2021554692A JP2021554692A JP2022525102A JP 2022525102 A JP2022525102 A JP 2022525102A JP 2021554692 A JP2021554692 A JP 2021554692A JP 2021554692 A JP2021554692 A JP 2021554692A JP 2022525102 A JP2022525102 A JP 2022525102A
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Japan
Prior art keywords
crystal form
form according
radiation
peaks
xrpd
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Pending
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JP2021554692A
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English (en)
Japanese (ja)
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JP2022525102A5 (enExample
Inventor
ステファニー アザリ，
メアリー チャヴェス，
ジャスティン マリノフスキ，
スティーブン エム． メネン，
ダレン エル． リード，
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Amgen Inc
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Amgen Inc
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Application filed by Amgen Inc filed Critical Amgen Inc
Publication of JP2022525102A publication Critical patent/JP2022525102A/ja
Publication of JP2022525102A5 publication Critical patent/JP2022525102A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2021554692A 2019-03-12 2020-03-12 心臓トロポニン活性化因子の多形 Pending JP2022525102A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962817194P 2019-03-12 2019-03-12
US62/817,194 2019-03-12
PCT/US2020/022221 WO2020185983A1 (en) 2019-03-12 2020-03-12 Polymorphs of a cardiac troponin activator

Publications (2)

Publication Number Publication Date
JP2022525102A true JP2022525102A (ja) 2022-05-11
JP2022525102A5 JP2022525102A5 (enExample) 2023-03-22

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ID=70190163

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JP2021554692A Pending JP2022525102A (ja) 2019-03-12 2020-03-12 心臓トロポニン活性化因子の多形

Country Status (6)

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US (1) US20220185791A1 (enExample)
EP (1) EP3938042A1 (enExample)
JP (1) JP2022525102A (enExample)
CN (1) CN114025845A (enExample)
TW (1) TWI857027B (enExample)
WO (1) WO2020185983A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20200924A1 (es) 2017-09-13 2020-09-14 Amgen Inc Compuestos de bisamida sustituida que activan el sarcomero cardiaco
SG11202109891WA (en) 2019-03-12 2021-10-28 Amgen Inc Polymorphs and cocrystals of a cardiac troponin activator
AU2022239717A1 (en) 2021-03-15 2023-11-02 Maze Therapeutics, Inc. Inhibitors of glycogen synthase 1 (gys1) and methods of use thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000055188A1 (en) * 1999-03-16 2000-09-21 C & C Research Laboratories Substituted proline derivatives and medicinal compositions containing the same
WO2009004383A2 (en) * 2007-07-03 2009-01-08 Astrazeneca Ab Aza-bicyclohexane compounds useful as anticoagulants
JP2016513683A (ja) * 2013-03-14 2016-05-16 アムジエン・インコーポレーテツド 複素環化合物およびその使用
JP7308816B2 (ja) * 2017-09-13 2023-07-14 アムジェン インコーポレイテッド ビスアミド筋節活性化化合物及びその使用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000055188A1 (en) * 1999-03-16 2000-09-21 C & C Research Laboratories Substituted proline derivatives and medicinal compositions containing the same
WO2009004383A2 (en) * 2007-07-03 2009-01-08 Astrazeneca Ab Aza-bicyclohexane compounds useful as anticoagulants
JP2016513683A (ja) * 2013-03-14 2016-05-16 アムジエン・インコーポレーテツド 複素環化合物およびその使用
JP7308816B2 (ja) * 2017-09-13 2023-07-14 アムジェン インコーポレイテッド ビスアミド筋節活性化化合物及びその使用

Also Published As

Publication number Publication date
CN114025845A (zh) 2022-02-08
TW202100517A (zh) 2021-01-01
TWI857027B (zh) 2024-10-01
EP3938042A1 (en) 2022-01-19
WO2020185983A1 (en) 2020-09-17
US20220185791A1 (en) 2022-06-16

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