JP2022524328A5 - - Google Patents

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Publication number
JP2022524328A5
JP2022524328A5 JP2021552549A JP2021552549A JP2022524328A5 JP 2022524328 A5 JP2022524328 A5 JP 2022524328A5 JP 2021552549 A JP2021552549 A JP 2021552549A JP 2021552549 A JP2021552549 A JP 2021552549A JP 2022524328 A5 JP2022524328 A5 JP 2022524328A5
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JP
Japan
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cells
class
nascent
antigens
mhc
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JP2021552549A
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English (en)
Japanese (ja)
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JP2022524328A (ja
JP7668742B2 (ja
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Priority claimed from PCT/US2020/021508 external-priority patent/WO2020181240A1/en
Publication of JP2022524328A publication Critical patent/JP2022524328A/ja
Publication of JP2022524328A5 publication Critical patent/JP2022524328A5/ja
Priority to JP2025066884A priority Critical patent/JP2025114587A/ja
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Publication of JP7668742B2 publication Critical patent/JP7668742B2/ja
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JP2021552549A 2019-03-06 2020-03-06 Ｍｈｃクラスｉｉモデルによる新生抗原の特定 Active JP7668742B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025066884A JP2025114587A (ja) 2019-03-06 2025-04-15 Ｍｈｃクラスｉｉモデルによる新生抗原の特定

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962814801P 2019-03-06 2019-03-06
US62/814,801 2019-03-06
US201962826822P 2019-03-29 2019-03-29
US62/826,822 2019-03-29
PCT/US2020/021508 WO2020181240A1 (en) 2019-03-06 2020-03-06 Identification of neoantigens with mhc class ii model

Related Child Applications (1)

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JP2025066884A Division JP2025114587A (ja) 2019-03-06 2025-04-15 Ｍｈｃクラスｉｉモデルによる新生抗原の特定

Publications (3)

Publication Number Publication Date
JP2022524328A JP2022524328A (ja) 2022-05-02
JP2022524328A5 true JP2022524328A5 (https=) 2023-03-13
JP7668742B2 JP7668742B2 (ja) 2025-04-25

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JP2021552549A Active JP7668742B2 (ja) 2019-03-06 2020-03-06 Ｍｈｃクラスｉｉモデルによる新生抗原の特定
JP2025066884A Pending JP2025114587A (ja) 2019-03-06 2025-04-15 Ｍｈｃクラスｉｉモデルによる新生抗原の特定

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Country Status (10)

Country Link
US (1) US20220154281A1 (https=)
EP (1) EP3935071A4 (https=)
JP (2) JP7668742B2 (https=)
KR (1) KR20210137110A (https=)
CN (1) CN113711239A (https=)
AU (1) AU2020232844A1 (https=)
CA (1) CA3132041A1 (https=)
IL (1) IL286086A (https=)
TW (1) TWI894138B (https=)
WO (1) WO2020181240A1 (https=)

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CN111630602A (zh) 2017-11-22 2020-09-04 磨石肿瘤生物技术公司 减少新抗原的接合表位呈递
US11848073B2 (en) * 2019-04-03 2023-12-19 University Of Central Florida Research Foundation, Inc. Methods and system for efficient indexing for genetic genealogical discovery in large genotype databases
WO2020206238A2 (en) 2019-04-05 2020-10-08 Rootpath Genomics, Inc. Compositions and methods for t-cell receptor gene assembly
US11644470B2 (en) * 2019-04-15 2023-05-09 Bioinformatics Solutions Inc. Systems and methods for de novo peptide sequencing using deep learning and spectrum pairs
US11727284B2 (en) * 2019-12-12 2023-08-15 Business Objects Software Ltd Interpretation of machine learning results using feature analysis
AU2021366741A1 (en) * 2020-10-23 2023-05-11 Rootpath Genomics, Inc. Compositions and methods for t-cell receptor identification
CN112910288B (zh) * 2020-12-08 2022-08-09 上海交通大学 一种基于逆变器散热器温度预测的过温预警方法
CN113255690B (zh) * 2021-04-15 2022-04-12 南昌大学 一种基于轻量级卷积神经网络的复合绝缘子憎水性检测方法
CN113160887B (zh) * 2021-04-23 2022-06-14 哈尔滨工业大学 一种融合了单细胞tcr测序数据的肿瘤新生抗原筛选方法
CN116264103A (zh) * 2021-12-14 2023-06-16 深圳华大基因股份有限公司 构建机器学习模型的方法、系统及用途
CN114023387B (zh) * 2022-01-05 2022-04-22 山东建筑大学 一种基于卷积神经网络的细胞反卷积预测方法
WO2023146978A2 (en) * 2022-01-26 2023-08-03 Memorial Sloan-Kettering Cancer Center Systems and methods for determining t-cell cross-reactivity between antigens
CN114446385B (zh) * 2022-01-29 2024-08-13 杭州纽安津生物科技有限公司 Hla ii型分子与多肽的亲和力预测模型的获取方法及装置
EP4490738A4 (en) * 2022-03-08 2026-03-04 Avalo Inc SYSTEM AND METHOD FOR GENOMIC ASSOCIATION
EP4519675A4 (en) * 2022-05-03 2026-04-08 3T Biosciences Inc T-LYMPHOCYTE TARGET DISCOVERY
CN115295084B (zh) * 2022-08-05 2026-03-17 南开大学 一种肿瘤新抗原免疫组库数据可视化分析方法和系统
CN120202297A (zh) * 2022-08-08 2025-06-24 北海道公立大学法人札幌医科大学 用于选择来自受试者的新抗原的方法
US20260120799A1 (en) * 2022-08-12 2026-04-30 Biontech Us Inc. Methods and systems for prediction of hla epitopes
WO2024192143A1 (en) * 2023-03-13 2024-09-19 Gritstone Bio, Inc. Epitope prediction via a learned genotype network across class ii mhc alleles
CN116469457B (zh) * 2023-06-14 2023-10-13 普瑞基准科技（北京）有限公司 Mhc与抗原多肽结合、呈递及免疫原性的预测模型训练方法和装置
CN117912568B (zh) * 2024-01-05 2024-08-06 中山大学 H9n2亚型禽流感毒株抗原性快速鉴别方法及装置
CN120089201B (zh) * 2025-04-30 2025-07-04 广东省农业科学院动物卫生研究所 一种基于深度学习的通用表位多肽筛选方法和系统
CN120600110B (zh) * 2025-08-06 2025-12-09 上海交通大学医学院附属仁济医院 基于人工智能的多变病原t细胞表位精准筛选方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014180490A1 (en) * 2013-05-10 2014-11-13 Biontech Ag Predicting immunogenicity of t cell epitopes
CA3017170C (en) * 2014-09-17 2021-03-23 The Johns Hopkins University Reagents and methods for identifying, enriching, and/or expanding antigen-specific t cells
ES2970865T3 (es) * 2015-12-16 2024-05-31 Gritstone Bio Inc Identificación, fabricación y uso de neoantígenos
WO2017194170A1 (en) * 2016-05-13 2017-11-16 Biontech Rna Pharmaceuticals Gmbh Methods for predicting the usefulness of proteins or protein fragments for immunotherapy
CA3060569A1 (en) * 2017-04-19 2018-10-25 Gritstone Oncology, Inc. Neoantigen identification, manufacture, and use
CN109145927A (zh) * 2017-06-16 2019-01-04 杭州海康威视数字技术股份有限公司 一种对形变图像的目标识别方法及装置

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