JP2022523742A5 - - Google Patents
Info
- Publication number
- JP2022523742A5 JP2022523742A5 JP2021544801A JP2021544801A JP2022523742A5 JP 2022523742 A5 JP2022523742 A5 JP 2022523742A5 JP 2021544801 A JP2021544801 A JP 2021544801A JP 2021544801 A JP2021544801 A JP 2021544801A JP 2022523742 A5 JP2022523742 A5 JP 2022523742A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- deuterated
- hydrogen
- undeuterated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962800239P | 2019-02-01 | 2019-02-01 | |
| US62/800,239 | 2019-02-01 | ||
| PCT/US2020/016394 WO2020160537A1 (en) | 2019-02-01 | 2020-02-03 | Bicyclic pyridine compositions and methods of using the same for cancer therapy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022523742A JP2022523742A (ja) | 2022-04-26 |
| JP2022523742A5 true JP2022523742A5 (enExample) | 2023-02-13 |
| JP7628252B2 JP7628252B2 (ja) | 2025-02-10 |
Family
ID=71842384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021544801A Active JP7628252B2 (ja) | 2019-02-01 | 2020-02-03 | 二環式ピリジン組成物およびがんの治療にそれを使用する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11572369B2 (enExample) |
| EP (1) | EP3917523B1 (enExample) |
| JP (1) | JP7628252B2 (enExample) |
| CN (1) | CN113677341B (enExample) |
| AU (1) | AU2020216498B2 (enExample) |
| CA (1) | CA3128377A1 (enExample) |
| ES (1) | ES2991429T3 (enExample) |
| WO (1) | WO2020160537A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024193640A1 (zh) * | 2023-03-22 | 2024-09-26 | 上海齐鲁制药研究中心有限公司 | Cdk抑制剂 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4271723A (en) | 1976-11-19 | 1981-06-09 | Caterpillar Tractor Co. | Power train with an auxiliary creeper drive system |
| GB9402029D0 (en) | 1994-02-03 | 1994-03-30 | Smithkline Beecham Plc | Novel formulation |
| DE60325051D1 (de) | 2002-06-06 | 2009-01-15 | Boehringer Ingelheim Pharma | SUBSTITUIERTE 3-AMINO-THIENO(2,3-b)PYRIDINE-2-AMIDE UND HERSTELLUNGSVERFAHREN SOWIE DEREN VERWENDUNG |
| US7205308B2 (en) * | 2002-09-04 | 2007-04-17 | Schering Corporation | Trisubstituted 7-aminopyrazolopyrimidines as cyclin dependent kinase inhibitors |
| EP1764367A1 (en) * | 2004-04-12 | 2007-03-21 | Sankyo Company, Limited | Thienopyridine derivatives |
| US20070021927A1 (en) | 2005-07-21 | 2007-01-25 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Selective resonance of chemical structures |
| US20070207201A1 (en) | 2006-03-06 | 2007-09-06 | Wyeth | Liquid and Semi-Solid Pharmaceutical Formulations and Processes |
| JP2008260693A (ja) * | 2007-04-10 | 2008-10-30 | Daiichi Sankyo Co Ltd | チエノピリジン−２−カルボキサミド誘導体を含有する医薬組成物 |
| US8598344B2 (en) | 2009-11-30 | 2013-12-03 | Senex Biotechnology | CDKI pathway inhibitors and uses thereof |
| EP2489354A1 (en) | 2011-02-18 | 2012-08-22 | Vironova AB | Pharmaceutical formulation of B220 for topical treatment of herpes |
| EA027531B1 (ru) | 2011-09-13 | 2017-08-31 | Игорь Ронинсон | ЛЕЧЕНИЕ ЗАБОЛЕВАНИЙ И НАРУШЕНИЙ, ВЫЗВАННЫХ АКТИВНОСТЬЮ ТРАНСКРИПЦИОННОГО ФАКТОРА NF-κB |
| KR20150023223A (ko) | 2012-02-02 | 2015-03-05 | 세넥스 바이오테크놀러지 인코포레이티드 | Ｃｄｋ8/ｃｄｋ19 선택성 억제제 및 암에 대한 항-전이 및 화학예방 방법에서 이들의 용도 |
| KR20160014568A (ko) * | 2012-11-01 | 2016-02-11 | 유니버시티 오브 싸우스 캐롤라이나 | 전립선암을 치료하는 방법 |
| WO2014087240A2 (en) * | 2012-12-04 | 2014-06-12 | Dalhousie University | Compositions, methods and kits for preventing, reducing, and eliminating cancer metastasis |
| CN103012428A (zh) * | 2013-01-08 | 2013-04-03 | 中国药科大学 | 4-(五元杂环并嘧啶/吡啶取代)氨基-1H-3-吡唑甲酰胺类CDK/Aurora双重抑制剂及其用途 |
| WO2014134169A1 (en) * | 2013-02-26 | 2014-09-04 | Senex Biotechnology, Inc. | Inhibitors of cdk8/19 for use in treating estrogen receptor positive breast cancer |
| WO2014164543A1 (en) * | 2013-03-13 | 2014-10-09 | The Regents Of The University Of Michigan | Compositions comprising thienopyrimidine and thienopyridine compounds and methods of use thereof |
| WO2014194245A2 (en) | 2013-05-31 | 2014-12-04 | Nimbus Iris, Inc. | Cdk8 inhibitors and uses thereof |
| US9937153B2 (en) | 2013-08-30 | 2018-04-10 | Merck Sharp & Dohme Ltd. | Oral pharmaceutical formulation of omarigliptin |
| AU2014369834B2 (en) | 2013-12-24 | 2018-12-20 | President And Fellows Of Harvard College | Cortistatin analogues and syntheses and uses thereof |
| US9566280B2 (en) * | 2014-01-28 | 2017-02-14 | Massachusetts Institute Of Technology | Combination therapies and methods of use thereof for treating cancer |
| NZ722345A (en) * | 2014-02-14 | 2018-02-23 | Inception 2 Inc | Pyrazolone compounds and uses thereof |
| WO2016018511A2 (en) | 2014-06-10 | 2016-02-04 | University Of South Carolina | Methods and compositions for treatment of her-positive cancers |
| JP2017522324A (ja) * | 2014-07-17 | 2017-08-10 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | 新規ナフチリジン及びイソキノリンならびにｃｄｋ８／１９阻害剤としてのその使用 |
| WO2016041618A1 (en) * | 2014-09-15 | 2016-03-24 | Merck Patent Gmbh | Substituted indazoles and related heterocycles |
| US20210322651A1 (en) | 2014-12-18 | 2021-10-21 | Senex Biotechnology, Inc. | Suppression of neointimal formation following vascular surgeru using cdk8 inhibitors |
| AU2016348659B2 (en) * | 2015-11-03 | 2022-07-28 | Apriligen, Inc. | Compounds for treatment of hypoproliferative disorders |
| US11014906B2 (en) | 2018-08-21 | 2021-05-25 | University Of South Carolina | Quinoline-based compounds and methods of inhibiting CDK8/19 |
| WO2020237014A1 (en) * | 2019-05-21 | 2020-11-26 | University Of South Carolina | 3-amino-4-(4-(4 (dimethylcarbamoyl) phenyl)-1,4-diazepan-1-yl) thieno [2,3-b] pyridine-2-carboxamide for use in cancer therapy and formulations comprising the same |
-
2020
- 2020-02-03 CN CN202080026293.4A patent/CN113677341B/zh active Active
- 2020-02-03 AU AU2020216498A patent/AU2020216498B2/en active Active
- 2020-02-03 CA CA3128377A patent/CA3128377A1/en active Pending
- 2020-02-03 WO PCT/US2020/016394 patent/WO2020160537A1/en not_active Ceased
- 2020-02-03 ES ES20749196T patent/ES2991429T3/es active Active
- 2020-02-03 EP EP20749196.0A patent/EP3917523B1/en active Active
- 2020-02-03 JP JP2021544801A patent/JP7628252B2/ja active Active
- 2020-02-03 US US17/427,487 patent/US11572369B2/en active Active
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